Renan P Souza

Renan P Souza

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Renan P Souza

Publications by authors named "Renan P Souza"

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DNA damage after chronic oxytocin administration in rats: a safety yellow light?

Metab Brain Dis 2017 02 3;32(1):51-55. Epub 2016 Aug 3.

Laboratório de Biologia Celular e Molecular, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense (UNESC), Avenida Universitaria, 1105 Bloco S, Criciuma, SC, 88806-100, Brazil.

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http://dx.doi.org/10.1007/s11011-016-9885-zDOI Listing
February 2017

Meta-analysis of dopamine receptor D1 rs4532 polymorphism and susceptibility to antipsychotic treatment response.

Psychiatry Res 2015 Sep 21;229(1-2):586-8. Epub 2015 Jul 21.

Grupo de Pesquisa em Bioestatística e Epidemiologia Molecular, Departamento de Biologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Programa de Pós-graduação em Genética, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2015.07.054DOI Listing
September 2015

Investigation of melanocortin system gene variants in antipsychotic-induced weight gain.

World J Biol Psychiatry 2014 Apr 24;15(3):251-8. Epub 2014 Feb 24.

Neurogenetics Section, Neuroscience Department, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , Toronto, ON , Canada.

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http://dx.doi.org/10.3109/15622975.2013.858827DOI Listing
April 2014

Investigation of melanocortin system gene variants in antipsychotic-induced weight gain.

World J Biol Psychiatry 2014 Apr 24;15(3):251-8. Epub 2014 Feb 24.

Neurogenetics Section, Neuroscience Department, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , Toronto, ON , Canada.

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http://dx.doi.org/10.3109/15622975.2013.858827DOI Listing
April 2014

Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D.

PLoS One 2013 6;8(2):e55239. Epub 2013 Feb 6.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055239PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566192PMC
December 2013

Chronic exposure to cigarette smoke during gestation results in altered cholinesterase enzyme activity and behavioral deficits in adult rat offspring: potential relevance to schizophrenia.

J Psychiatr Res 2013 Jun 6;47(6):740-6. Epub 2013 Mar 6.

Laboratório de Neurociências, Instituto Nacional de Ciência e Tecnologia Translacional em Medicina (INCT-TM), and Núcleo de Excelência em Neurociências Aplicadas de Santa Catarina (NENASC), Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, 88806-000 Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.jpsychires.2013.02.001DOI Listing
June 2013

Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment.

Pharmacogenet Genomics 2013 Feb;23(2):69-77

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298-0581, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835ca260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922978PMC
February 2013

The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain.

Prog Neuropsychopharmacol Biol Psychiatry 2012 Oct 27;39(1):96-101. Epub 2012 May 27.

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.pnpbp.2012.05.014DOI Listing
October 2012

Association study of GRIK1 gene polymorphisms in schizophrenia: case-control and family-based studies.

Hum Psychopharmacol 2012 Jul 22;27(4):345-51. Epub 2012 Jun 22.

Neurogenetics Section, Center for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hup.2233DOI Listing
July 2012

Dopamine D4 and D5 receptor gene variant effects on clozapine response in schizophrenia: replication and exploration.

Prog Neuropsychopharmacol Biol Psychiatry 2012 Apr 8;37(1):62-75. Epub 2011 Dec 8.

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.pnpbp.2011.11.018DOI Listing
April 2012

Association study between variants of AMP-activated protein kinase catalytic and regulatory subunit genes with antipsychotic-induced weight gain.

J Psychiatr Res 2012 Apr 2;46(4):462-8. Epub 2012 Feb 2.

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.jpsychires.2012.01.010DOI Listing
April 2012

Prolactin as a biomarker for treatment response and tardive dyskinesia in schizophrenia subjects: old thoughts revisited from a genetic perspective.

Hum Psychopharmacol 2011 Jan;26(1):21-7

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/hup.1161
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http://dx.doi.org/10.1002/hup.1161DOI Listing
January 2011

Genetic interactions in the adrenergic system genes: analysis of antipsychotic-induced weight gain.

Hum Psychopharmacol 2011 Aug 8;26(6):386-91. Epub 2011 Aug 8.

Neurogenetics Section, Centre for Addictions and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/hup.1219DOI Listing
August 2011

Lack of association of NALCN genetic variants with schizophrenia.

Psychiatry Res 2011 Feb 31;185(3):450-2. Epub 2010 Jul 31.

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.psychres.2010.07.009DOI Listing
February 2011

Prolactin as a biomarker for treatment response and tardive dyskinesia in schizophrenia subjects: old thoughts revisited from a genetic perspective.

Hum Psychopharmacol 2011 Jan;26(1):21-7

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/hup.1161
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http://dx.doi.org/10.1002/hup.1161DOI Listing
January 2011

Gene-gene interaction analyses between NMDA receptor subunit and dopamine receptor gene variants and clozapine response.

Pharmacogenomics 2011 Feb;12(2):277-91

Neurogenetics Section, Centre for Addiction & Mental Health, 250 College Street, Toronto, Ontario, 5T1R8, Canada.

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http://dx.doi.org/10.2217/pgs.10.182DOI Listing
February 2011

Prolactin as a biomarker for treatment response and tardive dyskinesia in schizophrenia subjects: old thoughts revisited from a genetic perspective.

Hum Psychopharmacol 2011 Jan;26(1):21-7

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/hup.1161
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http://dx.doi.org/10.1002/hup.1161DOI Listing
January 2011

Influence of neurexin 1 (NRXN1) polymorphisms in clozapine response.

Hum Psychopharmacol 2010 Nov 22;25(7-8):582-5. Epub 2010 Sep 22.

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/hup.1146DOI Listing
November 2010

Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis.

Pharmacogenomics 2010 Nov;11(11):1561-71

Neurogenetics Section, Centre for Addiction & Mental Health, 250 College Street, Toronto, ON, M5T 1R8, Canada.

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http://dx.doi.org/10.2217/pgs.10.123DOI Listing
November 2010

Association study of the GSK-3B gene with tardive dyskinesia in European Caucasians.

Eur Neuropsychopharmacol 2010 Oct 3;20(10):688-94. Epub 2010 Jun 3.

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.euroneuro.2010.05.002DOI Listing
October 2010

Phosphodiesterase 4B genetic variants are not associated with antipsychotic-induced tardive dyskinesia.

Int Clin Psychopharmacol 2010 Sep;25(5):264-9

Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/YIC.0b013e32833a5ff9DOI Listing
September 2010

Association of functional variants in the dopamine D2-like receptors with risk for gambling behaviour in healthy Caucasian subjects.

Biol Psychol 2010 Sep 7;85(1):33-7. Epub 2010 May 7.

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.biopsycho.2010.04.008DOI Listing
September 2010

Genetic association of the GDNF alpha-receptor genes with schizophrenia and clozapine response.

J Psychiatr Res 2010 Aug 29;44(11):700-6. Epub 2010 Jan 29.

Laboratorio de Neurociencia, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

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http://dx.doi.org/10.1016/j.jpsychires.2010.01.002DOI Listing
August 2010

Cocaine and amphetamine regulated transcript (CART) gene in the comorbidity of schizophrenia with alcohol use disorders and nicotine dependence.

Prog Neuropsychopharmacol Biol Psychiatry 2010 Aug 30;34(6):834-6. Epub 2010 Mar 30.

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.pnpbp.2010.03.030DOI Listing
August 2010

Variants in the oxytocin gene and risk for schizophrenia.

Schizophr Res 2010 Aug 23;121(1-3):279-80. Epub 2010 May 23.

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http://dx.doi.org/10.1016/j.schres.2010.04.019DOI Listing
August 2010

Schizophrenia severity and clozapine treatment outcome association with oxytocinergic genes.

Int J Neuropsychopharmacol 2010 Jul 3;13(6):793-8. Epub 2010 Mar 3.

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1017/S1461145710000167DOI Listing
July 2010

Inhibitory avoidance task does not change NCS-1 level in rat brain.

Brain Res Bull 2010 Jul 20;82(5-6):289-92. Epub 2010 May 20.

Laboratório de Neurociência e Instituto Nacional de Ciência e Tecnologia de Medicina Molecular, Departamento de Saúde Mental, Faculdade de Medicina da Universidade Federal de Minas Gerais, Av Alfredo Balena, 190 sl 114, Belo Horizonte 30130-100, MG, Brazil.

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http://dx.doi.org/10.1016/j.brainresbull.2010.04.014DOI Listing
July 2010

Glial cell line-derived neurotrophic factor receptor alpha 2 (GFRA2) gene is associated with tardive dyskinesia.

Psychopharmacology (Berl) 2010 Jun 6;210(3):347-54. Epub 2010 Apr 6.

Neurogenetics Section, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s00213-010-1829-4DOI Listing
June 2010

Lack of effects of typical and atypical antipsychotics in DARPP-32 and NCS-1 levels in PC12 cells overexpressing NCS-1.

J Negat Results Biomed 2010 Jun 19;9. Epub 2010 Jun 19.

Laboratório de Neurociências, Departamento de Saúde Mental, Faculdade de Medicina, Universidade Federal de Minas Gerais, Av Alfredo Balena 190, Belo Horizonte, MG, Brazil.

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http://dx.doi.org/10.1186/1477-5751-9-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912242PMC
June 2010

Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia.

Pharmacogenet Genomics 2010 Apr;20(4):274-6

Neurogenetics Section, Department of Neuroscience, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/FPC.0b013e328337ce3eDOI Listing
April 2010

Diurnal differences in memory and learning in young and adult rats treated with methylphenidate.

J Neural Transm (Vienna) 2010 Apr 6;117(4):457-62. Epub 2010 Mar 6.

Laboratory of Neuroscience, National Institute of Translational Science and Technology in Medicine, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, 88806-000 Criciúma, SC, Brazil.

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http://dx.doi.org/10.1007/s00702-010-0385-8DOI Listing
April 2010

Lack of association of GPX1 and MnSOD genes with symptom severity and response to clozapine treatment in schizophrenia subjects.

Hum Psychopharmacol 2009 Dec;24(8):676-9

Neurogenetics Section, CAMH and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/hup.1076DOI Listing
December 2009

Chronic methylphenidate-effects over circadian cycle of young and adult rats submitted to open-field and object recognition tests.

Curr Neurovasc Res 2009 Nov;6(4):259-66

Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.

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November 2009

Glutathione s-transferase variants in a brazilian population.

Pharmacology 2009 4;83(4):231-6. Epub 2009 Mar 4.

Laboratório de Farmacogenômica e Epidemiologia Molecular, Universidade Estadual de Santa Cruz, Ilhéus, Brazil.

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http://dx.doi.org/10.1159/000205823DOI Listing
June 2009

Pharmacogenetics of anxiolytic drugs.

J Neural Transm (Vienna) 2009 Jun 12;116(6):667-77. Epub 2009 May 12.

Neurogenetics Section, Centre for Addiction and Mental Health, 250 College Street, R-30, Toronto ONM5T1R8, Canada.

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http://link.springer.com/10.1007/s00702-009-0229-6
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http://dx.doi.org/10.1007/s00702-009-0229-6DOI Listing
June 2009

Cerebral DARPP-32 expression after methylphenidate administration in young and adult rats.

Int J Dev Neurosci 2009 Feb 8;27(1):1-7. Epub 2008 Nov 8.

Laboratório de Neurociência, Departamento de Saúde Mental, Faculdade de Medicina da Universidade Federal de Minas Gerais, Av Alfredo Balena, 190, Belo Horizonte, 30130-100 - MG, Brazil.

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http://dx.doi.org/10.1016/j.ijdevneu.2008.11.001DOI Listing
February 2009

Association of antipsychotic induced weight gain and body mass index with GNB3 gene: a meta-analysis.

Prog Neuropsychopharmacol Biol Psychiatry 2008 Dec 28;32(8):1848-53. Epub 2008 Aug 28.

Neurogenetics Section, Centre for Addiction and Mental Health, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.pnpbp.2008.08.014DOI Listing
December 2008

DARPP-32 expression in rat brain after an inhibitory avoidance task.

Neurochem Res 2008 Nov 16;33(11):2257-62. Epub 2008 Apr 16.

Laboratório de Neurociência e Departamento de Saúde Mental, Faculdade de Medicina da Universidade Federal de Minas Gerais, Av Alfredo Balena, 190 sl 325, Belo Horizonte, 30130-100, MG, Brazil.

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http://dx.doi.org/10.1007/s11064-008-9706-9DOI Listing
November 2008

Association study of GSK3 gene polymorphisms with schizophrenia and clozapine response.

Psychopharmacology (Berl) 2008 Oct 26;200(2):177-86. Epub 2008 May 26.

Grupo de Pesquisa em Neuropsiquiatria Clínica e Molecular, UFMG, Belo Horizonte, Brazil.

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http://dx.doi.org/10.1007/s00213-008-1193-9DOI Listing
October 2008

Association of antipsychotic induced weight gain and body mass index with GNB3 gene: a meta-analysis.

Prog Neuropsychopharmacol Biol Psychiatry 2008 Dec 28;32(8):1848-53. Epub 2008 Aug 28.

Neurogenetics Section, Centre for Addiction and Mental Health, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.pnpbp.2008.08.014DOI Listing
December 2008

Methylphenidate alters NCS-1 expression in rat brain.

Neurochem Int 2008 Jul 26;53(1-2):12-6. Epub 2008 Apr 26.

Grupo de Pesquisa em Neuropsiquiatria Clínica e Molecular, Universidade Federal de Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.

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http://dx.doi.org/10.1016/j.neuint.2008.04.007DOI Listing
July 2008

Is DARPP-32 a potential therapeutic target?

Expert Opin Ther Targets 2007 Dec;11(12):1649-61

Universidade Federal de Minas Gerais, Departamento de Farmacologia, Av Antonio Carlos, 6627 - Belo Horizonte-MG, 31270-901, Brazil.

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http://dx.doi.org/10.1517/14728222.11.12.1649 DOI Listing
December 2007

DARPP-32 expression in rat brain after electroconvulsive stimulation.

Brain Res 2007 Nov 25;1179:35-41. Epub 2007 Aug 25.

Grupo de Pesquisa em Neuropsiquiatria Clínica e Molecular, Universidade Federal de Minas Gerais, Av Antonio Carlos 6627, Belo Horizonte 31270-901, Minas Gerais, Brazil.

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http://dx.doi.org/10.1016/j.brainres.2007.08.043DOI Listing
November 2007

NCS-1 expression in rat brain after electroconvulsive stimulation.

Neurochem Res 2007 Jan 9;32(1):81-5. Epub 2006 Dec 9.

Grupo de Pesquisa em Neuropsiquiatria Clínica e Molecular, ICB, Universidade Federal de Minas Gerais, Av Antonio Carlos - 6627, Belo Horizonte 31270-901, MG, Brazil.

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http://dx.doi.org/10.1007/s11064-006-9228-2DOI Listing
January 2007

Dopaminergic intracellular signal integrating proteins: relevance to schizophrenia.

Dialogues Clin Neurosci 2006 ;8(1):95-100

Departamento de Farmacologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181764PMC
June 2006