Remko Hersmus

Remko Hersmus

UNVERIFIED PROFILE

Are you Remko Hersmus?   Register this Author

Register author
Remko Hersmus

Remko Hersmus

Publications by authors named "Remko Hersmus"

Are you Remko Hersmus?   Register this Author

33Publications

675Reads

5Profile Views

Histological Assessment of Gonads in DSD: Relevance for Clinical Management.

Sex Dev 2018 3;12(1-3):106-122. Epub 2017 Nov 3.

Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000481757DOI Listing
November 2018

The biology of germ cell tumors in disorders of sex development.

Clin Genet 2017 02 24;91(2):292-301. Epub 2016 Nov 24.

Department of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cge.12882DOI Listing
February 2017

Hormonal evaluation in relation to phenotype and genotype in 286 patients with a disorder of sex development from Indonesia.

Clin Endocrinol (Oxf) 2016 08 4;85(2):247-57. Epub 2016 Apr 4.

Department of Paediatrics, Division of Endocrinology, Sophia Children's Hospital, Erasmus University Medical Centre, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cen.13051DOI Listing
August 2016

SRY mutation analysis by next generation (deep) sequencing in a cohort of chromosomal Disorders of Sex Development (DSD) patients with a mosaic karyotype.

BMC Med Genet 2012 Nov 16;13:108. Epub 2012 Nov 16.

Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2350-13-108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538515PMC
November 2012

Application of the new classification on patients with a disorder of sex development in indonesia.

Int J Endocrinol 2012 29;2012:237084. Epub 2011 Dec 29.

Department of Human Genetics, Center for Biomedical Research, Faculty of Medicine Diponegoro University (FMDU), Semarang 50321, Indonesia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2012/237084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255103PMC
August 2012

Delayed Recognition of Disorders of Sex Development (DSD): A Missed Opportunity for Early Diagnosis of Malignant Germ Cell Tumors.

Int J Endocrinol 2012 19;2012:671209. Epub 2012 Jan 19.

Department of Pathology, Erasmus MC-University Medical Center Rotterdam, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2012/671209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272341PMC
August 2012

Gonadal tumours and DSD.

Best Pract Res Clin Endocrinol Metab 2010 Apr;24(2):291-310

Department of Pathology, Erasmus MC-University Medical Center Rotterdam, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.beem.2009.10.002DOI Listing
April 2010

Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.

J Biol Chem 2010 Feb 10;285(7):5097-105. Epub 2009 Dec 10.

Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.039958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836112PMC
February 2010

A novel SRY missense mutation affecting nuclear import in a 46,XY female patient with bilateral gonadoblastoma.

Eur J Hum Genet 2009 Dec 10;17(12):1642-9. Epub 2009 Jun 10.

Department of Pathology, Erasmus MC-University Medical Center Rotterdam, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2009.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987026PMC
December 2009

Recent developments in testicular germ cell tumor research.

Birth Defects Res C Embryo Today 2009 Mar;87(1):96-113

Department of Pathology, Erasmus MC, Erasmus University Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdrc.20140DOI Listing
March 2009

New insights into type II germ cell tumor pathogenesis based on studies of patients with various forms of disorders of sex development (DSD).

Mol Cell Endocrinol 2008 Sep 4;291(1-2):1-10. Epub 2008 Mar 4.

Department of Pathology, Erasmus MC-University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mce.2008.02.028DOI Listing
September 2008

Further characterization of the first seminoma cell line TCam-2.

Genes Chromosomes Cancer 2008 Mar;47(3):185-96

Department of Pathology, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Erasmus MC-University Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20520DOI Listing
March 2008

Chromosomes and expression in human testicular germ-cell tumors: insight into their cell of origin and pathogenesis.

Ann N Y Acad Sci 2007 Dec 2;1120:187-214. Epub 2007 Oct 2.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC-University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1196/annals.1411.000DOI Listing
December 2007

Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines.

Genes Chromosomes Cancer 2007 Oct;46(10):895-908

Department of Pathology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20475DOI Listing
October 2007

Tumor risk in disorders of sex development (DSD).

Best Pract Res Clin Endocrinol Metab 2007 Sep;21(3):480-95

Department of Pathology, Erasmus MC - University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Building Be, Room 430b, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S1521690X0700038
Publisher Site
http://dx.doi.org/10.1016/j.beem.2007.05.001DOI Listing
September 2007

Genomic and expression profiling of human spermatocytic seminomas: pathogenetic implications.

Int J Androl 2007 Aug 15;30(4):328-35; discussion 335-6. Epub 2007 Jun 15.

Department of Pathology, Erasmus MC - University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2605.2007.00779.xDOI Listing
August 2007

Androgen receptor ligand-binding domain interaction and nuclear receptor specificity of FXXLF and LXXLL motifs as determined by L/F swapping.

Mol Endocrinol 2006 Aug 20;20(8):1742-55. Epub 2006 Apr 20.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2005-0348DOI Listing
August 2006

Novel FXXFF and FXXMF motifs in androgen receptor cofactors mediate high affinity and specific interactions with the ligand-binding domain.

J Biol Chem 2006 Jul 11;281(28):19407-16. Epub 2006 May 11.

Department of Urology, Josephine Nefkens Institute, Erasmus MC, P. O. Box 1738, 3000 DR Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M602567200DOI Listing
July 2006

Antiandrogens prevent stable DNA-binding of the androgen receptor.

J Cell Sci 2005 Sep 1;118(Pt 18):4187-98. Epub 2005 Sep 1.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.02546DOI Listing
September 2005

Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptor.

Mol Endocrinol 2004 Sep 3;18(9):2132-50. Epub 2004 Jun 3.

Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2003-0375DOI Listing
September 2004

The androgen receptor ligand-binding domain stabilizes DNA binding in living cells.

J Struct Biol 2004 Jul;147(1):50-61

Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsb.2004.01.002DOI Listing
July 2004