Publications by authors named "Reinoud Gosens"

134Publications

Rejuvenating old lungs: Ain't no tonic like a drop of retinoic.

Authors:
Reinoud Gosens John-Poul Ng-Blichfeldt

Thorax 2021 Jan 21. Epub 2021 Jan 21.

MRC Laboratory of Molecular Biology, Cambridge, UK.

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January 2021

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung.

Authors:
Thomas M Conlon Gerrit John-Schuster Danijela Heide Dominik Pfister Mareike Lehmann Yan Hu Zeynep Ertüz Martin A Lopez Meshal Ansari Maximilian Strunz Christoph Mayr Ilias Angelidis Chiara Ciminieri Rita Costa Marlene Sophia Kohlhepp Adrien Guillot Gizem Günes Aicha Jeridi Maja C Funk Giorgi Beroshvili Sandra Prokosch Jenny Hetzer Stijn E Verleden Hani Alsafadi Michael Lindner Gerald Burgstaller Lore Becker Martin Irmler Michael Dudek Jakob Janzen Eric Goffin Reinoud Gosens Percy Knolle Bernard Pirotte Tobias Stoeger Johannes Beckers Darcy Wagner Indrabahadur Singh Fabian J Theis Martin Hrabé de Angelis Tracy O'Connor Frank Tacke Michael Boutros Emmanuel Dejardin Oliver Eickelberg Herbert B Schiller Melanie Königshoff Mathias Heikenwalder Ali Önder Yildirim

Nature 2021 Jan;589(7842):E6

Comprehensive Pneumology Center (CPC), Institute of Lung Biology and Disease, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Neuherberg, Germany.

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January 2021

Two-Year Outcomes for the Double-Blind, Randomized, Sham-Controlled Study of Targeted Lung Denervation in Patients with Moderate to Severe COPD: AIRFLOW-2.

Authors:
Arschang Valipour Pallav L Shah Felix J Herth Christophe Pison Christian Schumann Ralf-Harto Hübner Peter I Bonta Romain Kessler Wolfgang Gesierich Kaid Darwiche Bernd Lamprecht Thierry Perez Dirk Skowasch Gaetan Deslee Armelle Marceau Frank C Sciurba Reinoud Gosens Jorine E Hartman Francesca Conway Marina Duller Martin Mayse Holly S Norman Dirk-Jan Slebos

Int J Chron Obstruct Pulmon Dis 2020 5;15:2807-2816. Epub 2020 Nov 5.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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November 2020

Prostaglandin D: the end of a story or just the beginning?

Authors:
Huib A M Kerstjens Reinoud Gosens

Lancet Respir Med 2021 01 5;9(1):2-3. Epub 2020 Nov 5.

University of Groningen and University Medical Center Groningen, and Department of Molecular Pharmacology, University of Groningen, Groningen, Netherlands; Groningen Research Institute for Asthma and COPD, Groningen, Netherlands.

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January 2021

Inhibition of LTβR signalling activates WNT-induced regeneration in lung.

Authors:
Thomas M Conlon Gerrit John-Schuster Danijela Heide Dominik Pfister Mareike Lehmann Yan Hu Zeynep Ertüz Martin A Lopez Meshal Ansari Maximilian Strunz Christoph Mayr Ilias Angelidis Chiara Ciminieri Rita Costa Marlene Sophia Kohlhepp Adrien Guillot Gizem Günes Aicha Jeridi Maja C Funk Giorgi Beroshvili Sandra Prokosch Jenny Hetzer Stijn E Verleden Hani Alsafadi Michael Lindner Gerald Burgstaller Lore Becker Martin Irmler Michael Dudek Jakob Janzen Eric Goffin Reinoud Gosens Percy Knolle Bernard Pirotte Tobias Stoeger Johannes Beckers Darcy Wagner Indrabahadur Singh Fabian J Theis Martin Hrabé de Angelis Tracy O'Connor Frank Tacke Michael Boutros Emmanuel Dejardin Oliver Eickelberg Herbert B Schiller Melanie Königshoff Mathias Heikenwalder Ali Önder Yildirim

Nature 2020 12 4;588(7836):151-156. Epub 2020 Nov 4.

Comprehensive Pneumology Center (CPC), Institute of Lung Biology and Disease, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Neuherberg, Germany.

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December 2020

The genetics of asthma and the promise of genomics-guided drug target discovery.

Authors:
Zaid W El-Husseini Reinoud Gosens Frank Dekker Gerard H Koppelman

Lancet Respir Med 2020 10 7;8(10):1045-1056. Epub 2020 Sep 7.

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, Netherlands. Electronic address:

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October 2020

Reduced vitamin K status as a potentially modifiable risk factor of severe COVID-19.

Authors:
Anton S M Dofferhoff Ianthe Piscaer Leon J Schurgers Margot P J Visser Jody M W van den Ouweland Pim A de Jong Reinoud Gosens Tilman M Hackeng Henny van Daal Petra Lux Cecile Maassen Esther G A Karssemeijer Cees Vermeer Emiel F M Wouters Loes E M Kistemaker Jona Walk Rob Janssen

Clin Infect Dis 2020 Aug 27. Epub 2020 Aug 27.

Department of Pulmonary Medicine, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.

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August 2020

Advanced Modeling of Peripheral Neuro-Effector Communication and -Plasticity.

Authors:
Pien A Goldsteen Amalia M Dolga Reinoud Gosens

Physiology (Bethesda) 2020 09;35(5):348-357

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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September 2020

Wnt-5A/B Signaling in Hematopoiesis throughout Life.

Authors:
Marina Mastelaro de Rezende Giselle Zenker Justo Edgar Julian Paredes-Gamero Reinoud Gosens

Cells 2020 07 29;9(8). Epub 2020 Jul 29.

Department of Molecular Pharmacology, University of Groningen, Groningen 9713 AV, The Netherlands.

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July 2020

Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema.

Authors:
Yan Hu John-Poul Ng-Blichfeldt Chiharu Ota Chiara Ciminieri Wenhua Ren Pieter S Hiemstra Jan Stolk Reinoud Gosens Melanie Königshoff

Stem Cells 2020 Nov 18;38(11):1467-1478. Epub 2020 Jun 18.

Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Aurora, Colorado, USA.

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November 2020

A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-β Signaling and Activation of cAMP/PKA Signaling.

Authors:
Katarzyna Wójcik-Pszczoła Grażyna Chłoń-Rzepa Agnieszka Jankowska Marietta Ślusarczyk Paweł E Ferdek Agnieszka A Kusiak Artur Świerczek Krzysztof Pociecha Paulina Koczurkiewicz-Adamczyk Elżbieta Wyska Elżbieta Pękala Reinoud Gosens

Int J Mol Sci 2020 Jun 3;21(11). Epub 2020 Jun 3.

Department of Molecular Pharmacology, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.

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June 2020

Withdrawn: The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs.

Authors:
Mariska van den Berg Susan Nijboer-Brinksma Sophie Bos Maarten van den Berge David Lamb Martijn van Faassen Ido Kema Reinoud Gosens Loes Kistemaker

Br J Pharmacol 2020 Oct;177(20):4809

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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October 2020

Host-microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease.

Authors:
Reinoud Gosens Pieter S Hiemstra Ian M Adcock Ken R Bracke Robert P Dickson Philip M Hansbro Susanne Krauss-Etschmann Hermelijn H Smits Frank R M Stassen Sabine Bartel

Eur Respir J 2020 08 20;56(2). Epub 2020 Aug 20.

Early Life Origins of Chronic Lung Disease, Research Center Borstel, Leibniz Lung Center, Airway Research Center North, Member of the German Center for Lung Research (DZL), Borstel, Germany

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August 2020

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation.

Authors:
Tim Koopmans Laura Hesse Martijn C Nawijn Kuldeep Kumawat Mark H Menzen I Sophie T Bos Ron Smits Elvira R M Bakker Maarten van den Berge Gerard H Koppelman Victor Guryev Reinoud Gosens

Sci Rep 2020 04 21;10(1):6754. Epub 2020 Apr 21.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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April 2020

Cholinergic neuroplasticity in asthma driven by TrkB signaling.

Authors:
Guilherme Dragunas Manon E Woest Susan Nijboer Sophie T Bos Janet van Asselt Anne P de Groot Eva Vohlídalová Corneel J Vermeulen Benedikt Ditz Judith M Vonk Gerard H Koppelman Maarten van den Berge Nick H T Ten Hacken Wim Timens Carolina D Munhoz Y S Prakash Reinoud Gosens Loes E M Kistemaker

FASEB J 2020 06 11;34(6):7703-7717. Epub 2020 Apr 11.

Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands.

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June 2020

Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation.

Authors:
Marina Mastelaro de Rezende John-Poul Ng-Blichfeldt Giselle Zenker Justo Edgar Julian Paredes-Gamero Reinoud Gosens

Cell Signal 2020 03 17;67:109507. Epub 2019 Dec 17.

Department of Molecular Pharmacology, University of Groningen, Groningen 9713AV, Netherlands. Electronic address:

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March 2020

Hot off the press: downregulation of PRMT1 for long-lasting effects of bronchial thermoplasty.

Authors:
Siti Farah Rahmawati Reinoud Gosens

Eur Respir J 2019 12 4;54(6). Epub 2019 Dec 4.

Dept of Molecular Pharmacology and GRIAC Research Institute, University of Groningen, Groningen, The Netherlands

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December 2019

Novel phosphodiesterases inhibitors from the group of purine-2,6-dione derivatives as potent modulators of airway smooth muscle cell remodelling.

Authors:
Katarzyna Wójcik-Pszczoła Grażyna Chłoń-Rzepa Agnieszka Jankowska Eugenie Ellen Artur Świerczek Krzysztof Pociecha Paulina Koczurkiewicz Kamil Piska Anna Gawędzka Elżbieta Wyska Małgorzata Knapik-Czajka Elżbieta Pękala Reinoud Gosens

Eur J Pharmacol 2019 Dec 6;865:172779. Epub 2019 Nov 6.

Department of Molecular Pharmacology, University of Groningen, Antonius Deusinglaan 1, 9713, AV, Groningen, the Netherlands.

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December 2019

Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors.

Authors:
Xinhui Wu Eline M van Dijk John-Poul Ng-Blichfeldt I Sophie T Bos Chiara Ciminieri Melanie Königshoff Loes E M Kistemaker Reinoud Gosens

Cells 2019 09 25;8(10). Epub 2019 Sep 25.

Department of Molecular Pharmacology, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713AV Groningen, The Netherlands.

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September 2019

The Enhanced Adhesion of Eosinophils Is Associated with Their Prolonged Viability and Pro-Proliferative Effect in Asthma.

Authors:
Andrius Januskevicius Ieva Janulaityte Virginija Kalinauskaite-Zukauske Reinoud Gosens Kestutis Malakauskas

J Clin Med 2019 Aug 22;8(9). Epub 2019 Aug 22.

Department of Pulmonology, Lithuanian University of Health Sciences, LT-44307 Kaunas, Lithuania.

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August 2019