Publications by authors named "Reinhard Seger"

56Publications

Lentiviral gene therapy vector with UCOE stably restores function in iPSC-derived neutrophils of a CDG patient.

Matters (Zur) 2018 23;2018. Epub 2018 May 23.

Systems and Cell Biology of Neurodegeneration, University of Zurich, James Martin Stem Cell Facility, University of Oxford, Division of Immunology, University Children's Hospital Zurich, Div. of Immunology, University Children's Hospital Zurich, Children's Research Center, Associated Group Institute for Regenerative Medicine, Department of Psychiatry, Sir William Dunn School of Pathology, University of Oxford, Icahn School of Medicine at Mount Sinai, HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA, James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford, Professor emeritus University Children's Hospital Zürich, Division of Immunology, Professor emeritus Children's Research Center, Div. of Immunology, University Children's Hospital Zurich, Children's Research Center, Associated Group Institute for Regenerative Medicine, University of Zürich, Center for Applied Biotechnology and Molecular Medicine, University of Zürich, Div. of Immunology, University Children's Hospital Zürich, Children's Research Center, Associated Group Institute for Regenerative Medicine, University of Zürich.

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May 2018

Modern management of primary T-cell immunodeficiencies.

Pediatr Allergy Immunol 2014 Jun 3;25(4):300-13. Epub 2014 Jan 3.

Division of Immunology, Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Switzerland.

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June 2014

In memory of Prof. Dr. med Walter H. Hitzig: A pioneer of paediatrics and paediatric immunology.

Eur J Pediatr 2013 Mar 22;172(3):287-8. Epub 2012 Dec 22.

University Children's Hospital, Steinwiesstr. 75, CH-8032, Zürich, Switzerland,

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March 2013

Gene therapy for primary immunodeficiencies: Part 2.

Curr Opin Immunol 2012 Oct 18;24(5):585-91. Epub 2012 Aug 18.

San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Division of Regenerative Medicine, San Raffaele Scientific Institute, Milan, Italy.

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October 2012

Modern management of primary B-cell immunodeficiencies.

Pediatr Allergy Immunol 2011 Dec;22(8):758-69

Division of Immunology, Haematology and BMT, Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, University Children's Hospital Zurich, Zürich, Switzerland.

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December 2011

Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.

J Exp Med 2011 Aug 4;208(8):1635-48. Epub 2011 Jul 4.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Medical School, Institut National de la Santé et de la Recherche Médicale U980 and University Paris Descartes, 75015 Paris, France.

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August 2011

Advances in the diagnosis and treatment of chronic granulomatous disease.

Authors:
Reinhard A Seger

Curr Opin Hematol 2011 Jan;18(1):36-41

University Children's Hospital, Zürich, Switzerland.

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January 2011

Gene therapy of chronic granulomatous disease: the engraftment dilemma.

Mol Ther 2011 Jan 2;19(1):28-35. Epub 2010 Nov 2.

Institute for Biomedical Research, Georg-Speyer-Haus, Frankfurt, Germany.

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January 2011

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease.

Blood 2010 Sep 21;116(9):1570-3. Epub 2010 May 21.

Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Berlin, Germany.

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September 2010

Indications for hemopoietic stem cell transplantation.

Immunol Allergy Clin North Am 2010 May;30(2):261-2

Division of Immunology & Allergy, The Canadian Centre for Primary Immunodeficiency, The Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

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May 2010

Hematopoietic stem cell transplantation for chronic granulomatous disease.

Authors:
Reinhard A Seger

Immunol Allergy Clin North Am 2010 May;30(2):195-208

Division of Immunology/Hematology/BMT, University Children's Hospital, Steinwiesstrasse 75, Zürich 8032, Switzerland.

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May 2010

MHC class II molecules enhance Toll-like receptor mediated innate immune responses.

PLoS One 2010 Jan 20;5(1):e8808. Epub 2010 Jan 20.

Division of Immunology/Allergology, University of Zurich, Children's Hospital, Zurich, Switzerland.

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January 2010

Primary immunodeficiencies: 2009 update.

J Allergy Clin Immunol 2009 Dec;124(6):1161-78

Division of Immunology, Children's Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

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December 2009

Restoration of NET formation by gene therapy in CGD controls aspergillosis.

Blood 2009 Sep 18;114(13):2619-22. Epub 2009 Jun 18.

Division of Immunology/Haematology/BMT, University Children's Hospital Zurich, Zurich, Switzerland.

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September 2009

Modern management of chronic granulomatous disease.

Authors:
Reinhard A Seger

Br J Haematol 2008 Feb;140(3):255-66

Division Immunology/Haematology, University Children's Hospital of Zurich, Zurich, Switzerland.

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February 2008

Advances in the treatment of Chronic Granulomatous Disease by gene therapy.

Curr Gene Ther 2007 Jun;7(3):155-61

Department of Internal Medicine II, Hematology/Oncology, University Medical School Frankfurt, Theodor-Stern-Kai 7, 60596 Frankfurt, Germany.

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June 2007

Factors influencing the efficacy of intra-articular steroid injections in patients with juvenile idiopathic arthritis.

Eur J Pediatr 2008 Apr 12;167(4):425-30. Epub 2007 Jun 12.

Department of Paediatrics, University Children's Hospital, Zurich, Switzerland.

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April 2008

Gene therapy for chronic granulomatous disease.

Curr Opin Mol Ther 2006 Oct;8(5):415-22

Institute for Biomedical Research, Georg-Speyer-Haus, Paul-Ehrlich-Strasse 42-44, 60596 Frankfurt, Germany.

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October 2006

Characterization of 17 new cases of X-linked chronic granulomatous disease with seven novel mutations in the CYBB gene.

Exp Hematol 2006 Apr;34(4):528-35

University Children's Hospital, Division of Immunology/Hematology/BMT, Zurich, Switzerland.

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April 2006

Successful low toxicity hematopoietic stem cell transplantation for high-risk adult chronic granulomatous disease patients.

Transplantation 2005 Jun;79(11):1596-606

Division of Immunology/Hematology/BMT, University Children's Hospital, CH-8032 Zurich, Switzerland.

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June 2005

The chronicles of chronic granulomatous disease.

Clin Immunol 2005 Aug;116(2):99-100

Allergy and Immunology, The Children's Hospital of Philadelphia, Civic Center, Philadelphia, PA, USA.

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August 2005

Primary immunodeficiency diseases: an update.

J Allergy Clin Immunol 2004 Sep;114(3):677-87

Department of Pediatrics, University of Brescia Spedali Civili, Brescia, Italy.

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September 2004

Gene therapy of hematopoietic stem cells: strategies for improvement.

News Physiol Sci 2002 Jun;17:87-92

Division of Immunology/Hematology/Oncology, University-Children's Hospital Zurich, CH-8032 Zurich, Switzerland.

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June 2002