Publications by authors named "Reiner Aichholz"

18Publications

Discovery and profiling of a selective and efficacious Syk inhibitor.

J Med Chem 2015 Feb 9;58(4):1950-63. Epub 2015 Feb 9.

Global Discovery Chemistry, ‡Analytical Sciences & Imaging, §Autoimmunity, Transplantation and Inflammation Research, Novartis Institutes for Biomedical Research , 4056 Basel, Switzerland.

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February 2015

The kinetic deuterium isotope effect as applied to metabolic deactivation of imatinib to the des-methyl metabolite, CGP74588.

Bioorg Med Chem 2013 Jun 1;21(11):3231-9. Epub 2013 Apr 1.

Disease Area Oncology, Novartis Institutes for Biomedical Research, CH-4002 Basel, Switzerland.

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June 2013

Biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589).

Drug Metab Dispos 2012 May 16;40(5):1041-50. Epub 2012 Feb 16.

Global Ciscovery Chemistry, Novartis Institutes for BioMedical Research, WKL-122.P.37, CH-4002 Basel, Switzerland.

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May 2012

Dipeptide nitrile inhibitors of cathepsin K.

Bioorg Med Chem Lett 2006 May 9;16(9):2549-54. Epub 2006 Feb 9.

Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.

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May 2006