Publications by authors named "Reiko Nishihara"

100Publications

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.

Nat Commun 2020 07 20;11(1):3644. Epub 2020 Jul 20.

Public Health Sciences Division, Fred Hutchinson Cancer Research Centre, 1100 Fairview Ave N, Seattle, WA, 98109, USA.

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http://dx.doi.org/10.1038/s41467-020-17386-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371703PMC
July 2020

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma.

Nat Commun 2019 07 2;10(1):2910. Epub 2019 Jul 2.

Molecular Neurosurgery Laboratory and the Brain Tumor Research Center and Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, MA, USA.

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http://dx.doi.org/10.1038/s41467-019-10993-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606647PMC
July 2019

Calcium intake and colon cancer risk subtypes by tumor molecular characteristics.

Cancer Causes Control 2019 Jun 8;30(6):637-649. Epub 2019 Apr 8.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s10552-019-01165-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546870PMC
June 2019

Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial.

Eur J Cancer 2019 04 1;111:82-93. Epub 2019 Mar 1.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436990PMC
April 2019

The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome.

Am J Pathol 2018 12 20;188(12):2839-2852. Epub 2018 Sep 20.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284552PMC
December 2018

Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour.

Eur J Cancer 2018 11 13;103:98-107. Epub 2018 Sep 13.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183110
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http://dx.doi.org/10.1016/j.ejca.2018.07.130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195453PMC
November 2018

Insights into Pathogenic Interactions Among Environment, Host, and Tumor at the Crossroads of Molecular Pathology and Epidemiology.

Annu Rev Pathol 2019 01 20;14:83-103. Epub 2018 Aug 20.

Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts 02215, USA; email: , ,

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http://dx.doi.org/10.1146/annurev-pathmechdis-012418-012818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345592PMC
January 2019

Diets That Promote Colon Inflammation Associate With Risk of Colorectal Carcinomas That Contain Fusobacterium nucleatum.

Clin Gastroenterol Hepatol 2018 10 24;16(10):1622-1631.e3. Epub 2018 Apr 24.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.cgh.2018.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151288PMC
October 2018

Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma.

Clin Cancer Res 2018 06 6;24(11):2574-2584. Epub 2018 Mar 6.

Harvey W. Cushing Neuro-oncology Laboratories (HCNL), Department of Neurosurgery, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800093PMC
June 2018

Inherited DNA-Repair Defects in Colorectal Cancer.

Am J Hum Genet 2018 03 22;102(3):401-414. Epub 2018 Feb 22.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985280PMC
March 2018

Utility of inverse probability weighting in molecular pathological epidemiology.

Eur J Epidemiol 2018 04 20;33(4):381-392. Epub 2017 Dec 20.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s10654-017-0346-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948129PMC
April 2018

Cell Cycle Protein Expression in Neuroendocrine Tumors: Association of CDK4/CDK6, CCND1, and Phosphorylated Retinoblastoma Protein With Proliferative Index.

Pancreas 2017 Nov/Dec;46(10):1347-1353

From the *Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA; †Medical Oncology Department 2, Chinese PLA General Hospital, Beijing, China; ‡Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA; §Collaborative Innovation Center of Tianjin for Medical Epigenetic, Key Laboratory of Hormone and Development (Ministry of Health), Metabolic Disease Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin; ∥College of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, China; ¶Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA; #Department of Epidemiology and Biostatistics, and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Huazhong University of Science and Technology, Wuhan, China; **Department of Epidemiology, Harvard T.H. Chan School of Public Health; ††Department of Biostatistics, Harvard T.H. Chan School of Public Health; ‡‡Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School; §§Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; ∥∥Yale Cancer Center; ¶¶Department of Medicine, Yale University School of Medicine; and ##Smilow Cancer Hospital, New Haven, CT.

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http://Insights.ovid.com/crossref?an=00006676-201711000-0001
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http://dx.doi.org/10.1097/MPA.0000000000000944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645256PMC
June 2018

Association Between Inflammatory Diet Pattern and Risk of Colorectal Carcinoma Subtypes Classified by Immune Responses to Tumor.

Gastroenterology 2017 12 1;153(6):1517-1530.e14. Epub 2017 Sep 1.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.08.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705461PMC
December 2017

The competing risks Cox model with auxiliary case covariates under weaker missing-at-random cause of failure.

Lifetime Data Anal 2018 07 4;24(3):425-442. Epub 2017 Aug 4.

Departments of Biostatistics and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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http://link.springer.com/10.1007/s10985-017-9401-8
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http://dx.doi.org/10.1007/s10985-017-9401-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797530PMC
July 2018

Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?

J Diabetes Complications 2017 Jul 13;31(7):1228-1236. Epub 2017 Apr 13.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Ave., Boston, MA 02215. Electronic address:

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http://dx.doi.org/10.1016/j.jdiacomp.2017.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501176PMC
July 2017

Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.

J Clin Oncol 2017 Jun 13;35(16):1836-1844. Epub 2017 Apr 13.

Tsuyoshi Hamada, Zhi Rong Qian, Yohei Masugi, Juhong Yang, Kosuke Mima, Keisuke Kosumi, Li Liu, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, Jeffrey A. Meyerhardt, Marios Giannakis, Scott J. Rodig, Gordon J. Freeman, Charles S. Fuchs, Reiko Nishihara, and Shuji Ogino, Dana-Farber Cancer Institute and Harvard Medical School; Yin Cao, Mingyang Song, and Andrew T. Chan, Massachusetts General Hospital and Harvard Medical School; Yin Cao, Mingyang Song, Li Liu, NaNa Keum, Kana Wu, Edward L. Giovannucci, Daniel Nevo, Molin Wang, Reiko Nishihara, and Shuji Ogino, Harvard T.H. Chan School of Public Health; Jonathan A. Nowak, Xuehong Zhang, Edward L. Giovannucci, Marios Giannakis, Gordon J. Freeman, Molin Wang, Andrew T. Chan, Charles S. Fuchs, and Shuji Ogino, Brigham and Women's Hospital and Harvard Medical School, Boston; Marios Giannakis and Andrew T. Chan, Broad Institute of MIT and Harvard University, Cambridge, MA; Li Liu, Huazhong University of Science and Technology, Wuhan; Yan Shi, Chinese People's Liberation Army General Hospital, Beijing; and Mancang Gu, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.

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http://dx.doi.org/10.1200/JCO.2016.70.7547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455595PMC
June 2017

Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.

Oncoimmunology 2017 31;6(3):e1284720. Epub 2017 Jan 31.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1080/2162402X.2017.1284720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384412PMC
January 2017

Post-colonoscopy colorectal cancer: the key role of molecular pathological epidemiology.

Transl Gastroenterol Hepatol 2017 15;2. Epub 2017 Feb 15.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; ; Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA;; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.21037/tgh.2017.01.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334563PMC
February 2017

Dietary Patterns and Risk of Colorectal Cancer: Analysis by Tumor Location and Molecular Subtypes.

Gastroenterology 2017 06 27;152(8):1944-1953.e1. Epub 2017 Feb 27.

Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447483PMC
June 2017

Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue.

JAMA Oncol 2017 Jul;3(7):921-927

Division of MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts4Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts7Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts9Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts13Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2016.6374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502000PMC
July 2017

A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers.

Am J Gastroenterol 2017 03 24;112(3):493-501. Epub 2017 Jan 24.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ajg.2016.589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342916PMC
March 2017

Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors.

Pancreas 2016 11;45(10):1386-1393

From the *Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; †Department of Geriatric Gastroenterology, Chinese PLA General Hospital, Beijing, China; ‡Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA; §Collaborative Innovation Center of Tianjin for Medical Epigenetics, Key Laboratory of Hormone and Development (Ministry of Health), Metabolic Disease Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China; ∥IPSEN Bioscience Inc, Global Drug Discovery Department, Cambridge, MA; ¶IPSEN Innovation, Global Drug Discovery Department, Les Ulis, France; Departments of #Biostatistics, and **Epidemiology, Harvard T.H. Chan School of Public Health, ††Massachusetts General Hospital, ‡‡Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, §§Department of Radiology, Massachusetts General Hospital, and ∥∥Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://pdfs.journals.lww.com/pancreasjournal/2016/11000/Asso
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067972PMC
http://dx.doi.org/10.1097/MPA.0000000000000700DOI Listing
November 2016

Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis.

J Gastroenterol 2017 Mar 13;52(3):265-275. Epub 2016 Oct 13.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Ave., Room SM1036, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s00535-016-1272-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325774PMC
March 2017

Regular Aspirin Use Associates With Lower Risk of Colorectal Cancers With Low Numbers of Tumor-Infiltrating Lymphocytes.

Gastroenterology 2016 11 27;151(5):879-892.e4. Epub 2016 Jul 27.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.07.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159194PMC
November 2016

All Biomedical and Health Science Researchers, Including Laboratory Physicians and Scientists, Need Adequate Education and Training in Study Design and Statistics.

Clin Chem 2016 07;62(7):1039-40

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Departments of Epidemiology, Nutrition, and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA.

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http://dx.doi.org/10.1373/clinchem.2016.257873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930005PMC
July 2016

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Cell Rep 2016 Apr 14;15(4):857-865. Epub 2016 Apr 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850357PMC
April 2016

Marine ω-3 Polyunsaturated Fatty Acid Intake and Risk of Colorectal Cancer Characterized by Tumor-Infiltrating T Cells.

JAMA Oncol 2016 Sep;2(9):1197-206

Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston2Division of Gastroenterology, Massachusetts General Hospital, Boston12Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts13Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge.

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http://dx.doi.org/10.1001/jamaoncol.2016.0605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016204PMC
September 2016

MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival.

Clin Cancer Res 2016 08 8;22(15):3841-8. Epub 2016 Mar 8.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970894PMC
August 2016

Population-wide Impact of Long-term Use of Aspirin and the Risk for Cancer.

JAMA Oncol 2016 Jun;2(6):762-9

Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston3Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston8Channing Division of Network Medicine, Brigham.

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http://dx.doi.org/10.1001/jamaoncol.2015.6396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900902PMC
June 2016

Review Article: The Role of Molecular Pathological Epidemiology in the Study of Neoplastic and Non-neoplastic Diseases in the Era of Precision Medicine.

Epidemiology 2016 07;27(4):602-11

From the aDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; bDivision of MPE Molecular Pathological Epidemiology, Brigham and Women's Hospital, Boston, MA; cDepartment of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; dDepartment of Medical Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA; eDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA; fDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA; gYale Institute for Network Science, Yale University, New Haven, CT; hInstitute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom; iDivision of Gastroenterology, Massachusetts General Hospital, Boston, MA; jChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; kDepartment of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN; lDivision of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; mDepartment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; nDivision of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, MA; and oDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1097/EDE.0000000000000471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892980PMC
July 2016

Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis.

Br J Cancer 2016 Jan 7;114(2):199-206. Epub 2016 Jan 7.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue M420, Boston, MA 02215, USA.

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http://dx.doi.org/10.1038/bjc.2015.347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815802PMC
January 2016

Integration of molecular pathology, epidemiology and social science for global precision medicine.

Expert Rev Mol Diagn 2016 4;16(1):11-23. Epub 2015 Dec 4.

c Department of Pathology , Brigham and Women's Hospital and Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1586/14737159.2016.1115346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713314PMC
October 2016

Prediagnosis Plasma Adiponectin in Relation to Colorectal Cancer Risk According to KRAS Mutation Status.

J Natl Cancer Inst 2016 Apr 23;108(4). Epub 2015 Nov 23.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (KI, RN, MY, PL, ZRQ, SAK, KM, YS, YI, CSF, SO); Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD (KI, CCH); Division of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan (KI); Department of Nutrition (MS, RN, EG, KW), Department of Epidemiology (MS, EG, SO), and Department of Biostatistics (RN), Harvard T. H. Chan School of Public Health, Boston, MA; Channing Division of Network Medicine, Department of Medicine (SJ, XZ, EG, CSF, EC, ATC) and Department of Pathology (SO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Division of Gastroenterology, Massachusetts General Hospital, Boston, MA (PL, ATC); Department of Oncology, McGill University, Montreal, Quebec, Canada (MNP); Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (CSM); Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA (CSM); Department of Dermatology, Warren Alpert Medical School of Brown University, Province, RI (EC).

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http://jnci.oxfordjournals.org/content/108/4/djv363.full.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv36
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http://dx.doi.org/10.1093/jnci/djv363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668768PMC
April 2016

Molecular pathological epidemiology gives clues to paradoxical findings.

Eur J Epidemiol 2015 Oct 7;30(10):1129-35. Epub 2015 Oct 7.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave., Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s10654-015-0088-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639412PMC
October 2015

Postdiagnostic intake of one-carbon nutrients and alcohol in relation to colorectal cancer survival.

Am J Clin Nutr 2015 Nov 30;102(5):1134-41. Epub 2015 Sep 30.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA; Department of Pathology, Brigham and Women's Hospital, Boston, MA

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http://dx.doi.org/10.3945/ajcn.115.115162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625593PMC
November 2015

MicroRNA MIR21 and T Cells in Colorectal Cancer.

Cancer Immunol Res 2016 Jan 29;4(1):33-40. Epub 2015 Sep 29.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703429PMC
January 2016

A longitudinal twin study on Tojikomori and depressive symptoms in Japanese elderly.

Psychogeriatrics 2016 Jul 29;16(4):255-62. Epub 2015 Sep 29.

Center for Twin Research, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1111/psyg.12157DOI Listing
July 2016

Fusobacterium nucleatum and T Cells in Colorectal Carcinoma.

JAMA Oncol 2015 Aug;1(5):653-61

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts3Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts5Department of Pathology, Brigham and Women's Hospital.

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http://dx.doi.org/10.1001/jamaoncol.2015.1377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537376PMC
August 2015

Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer.

Carcinogenesis 2015 Sep 12;36(9):999-1007. Epub 2015 Jun 12.

Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA, Department of Epidemiology, Indiana University School of Public Health, Indianapolis, IN, USA,

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http://carcin.oxfordjournals.org/content/early/2015/07/07/ca
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573660PMC
September 2015

Association Between Plasma Levels of Macrophage Inhibitory Cytokine-1 Before Diagnosis of Colorectal Cancer and Mortality.

Gastroenterology 2015 Sep 27;149(3):614-22. Epub 2015 May 27.

Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.05.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550565PMC
September 2015

LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.

Genes Dev 2015 May 8;29(10):1074-86. Epub 2015 May 8.

Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts 02115, USA; Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA; Harvard Stem Cell Institute, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Boston, Massachusetts 02138, USA

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http://dx.doi.org/10.1101/gad.256693.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441054PMC
May 2015

Marine ω-3 polyunsaturated fatty acids and risk of colorectal cancer according to microsatellite instability.

J Natl Cancer Inst 2015 Apr 25;107(4). Epub 2015 Mar 25.

Department of Nutrition (MS, RN, KW, ELG) and Department of Epidemiology (MS, ELG, SO), Harvard School of Public Health, Boston, MA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (RN, ZRQ, SAK, YS, KM, AM, JY, CSF, SO); Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD (KI); Channing Division of Network Medicine, Department of Medicine (CSF, ELG, SO, ATC) and Department of Pathology (SO), Harvard Medical School, Brigham and Women's Hospital, Boston, MA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (ATC).

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http://jnci.oxfordjournals.org/content/107/4/djv007.full.pdf
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djv007
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http://dx.doi.org/10.1093/jnci/djv007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402363PMC
April 2015

Lifecourse epidemiology and molecular pathological epidemiology.

Am J Prev Med 2015 Jan;48(1):116-9

Department of Epidemiology, Harvard School of Public Health; Department of Medical Oncology, Harvard Medical School, Harvard University, Boston, Massachusetts; Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts; Department of Pathology, Harvard Medical School, Harvard University, Boston, Massachusetts; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.amepre.2014.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274745PMC
January 2015

Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region.

Am J Clin Nutr 2014 Dec 8;100(6):1479-88. Epub 2014 Oct 8.

From the Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (RN, ZRQ, MY, KM, YS, SAK, KI, CSF, and SO); the Departments of Nutrition (RN, KW, and ELG), Epidemiology (MW, ELG, SO, and ESS), and Biostatistics (MW), Harvard School of Public Health, Boston, MA; the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (MW, XZ, KW, ELG, ATC, CSF, and ESS); the Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan (YB); the Division of Gastroenterology, Massachusetts General Hospital, Boston, MA (ATC); and Applied Cancer Research-Institution for Translational Research Vienna, Vienna, Austria (ESS).

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http://dx.doi.org/10.3945/ajcn.114.095539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232016PMC
December 2014

RNF43 is frequently mutated in colorectal and endometrial cancers.

Nat Genet 2014 Dec 26;46(12):1264-6. Epub 2014 Oct 26.

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [3] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283570PMC
December 2014

Tumor LINE-1 methylation level and microsatellite instability in relation to colorectal cancer prognosis.

J Natl Cancer Inst 2014 Sep 4;106(9). Epub 2014 Sep 4.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (KI, MY, RN, PL, ZRQ, AK, SAK, KM, YS, JAM, CSF, SO); Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD (KI, CCH); Department of Nutrition, Harvard School of Public Health, Boston, MA (RN, AK, KW); Gastrointestinal Research Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK (PL); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA (SJ, XZ, EC, ATC, CSF); Department of Dermatology, The Warren Alpert Medical School of Brown University, Province, RI (EC); Division of Gastroenterology, Massachusetts General Hospital, Boston, MA (ATC); Department of Epidemiology, Harvard School of Public Health, Boston, MA (SO); Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA (SO).

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http://dx.doi.org/10.1093/jnci/dju195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161997PMC
September 2014

Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions.

Am J Gastroenterol 2014 Aug 17;109(8):1205-14. Epub 2014 Jun 17.

1] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA [2] Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA [3] Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ajg.2014.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125459PMC
August 2014

Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression.

Mod Pathol 2015 Jan 13;28(1):14-29. Epub 2014 Jun 13.

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA [2] Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA [3] Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2014.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265316PMC
January 2015

Reply: To PMID 24047059.

Gastroenterology 2014 Jul 24;147(1):246-7. Epub 2014 May 24.

Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1053/j.gastro.2014.05.018DOI Listing
July 2014

Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD).

Sci Transl Med 2014 Apr;6(233):233re2

Department of Medicine and Case Comprehensive Cancer Center, Case Western Reserve University and University Hospitals Case Medical Center, 10900 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1126/scitranslmed.3008481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030641PMC
April 2014