Reika Iwakawa

Reika Iwakawa

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Reika Iwakawa

Reika Iwakawa

Publications by authors named "Reika Iwakawa"

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26Publications

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Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.

Int J Oncol 2015 3;46(6):2389-98. Epub 2015 Apr 3.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.3892/ijo.2015.2951DOI Listing
January 2016

KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.

Cancer Res 2015 Sep 24;75(18):3936-45. Epub 2015 Jul 24.

Cancer Epigenetics Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain. Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain. Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3702DOI Listing
September 2015

Comprehensive genomic profiles of small cell lung cancer.

Nature 2015 Aug 13;524(7563):47-53. Epub 2015 Jul 13.

1] Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany. [2] Department of Pathology, University Hospital Cologne, 50937 Cologne, Germany.

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http://dx.doi.org/10.1038/nature14664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861069PMC
August 2015

Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing.

Carcinogenesis 2015 Jun 11;36(6):616-21. Epub 2015 Apr 11.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan, Cancer Genome Biology Group, Institute of Predictive and Personalized Medicine of Cancer, 08916 Barcelona, Spain

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http://dx.doi.org/10.1093/carcin/bgv026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462675PMC
June 2015

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.

J Thorac Oncol 2014 Sep;9(9):1324-31

*Division of Thoracic Oncology, National Cancer Center Hospital East; †Exploratory Oncology Research and Clinical Trial Center, National Cancer Center; ‡Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East; §Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan; and ‖Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154841PMC
September 2014

ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma.

Cancer Sci 2014 Apr 19;105(4):490-7. Epub 2014 Mar 19.

Department of Pathology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.

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http://doi.wiley.com/10.1111/cas.12363
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http://dx.doi.org/10.1111/cas.12363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317802PMC
April 2014

TSPAN2 is involved in cell invasion and motility during lung cancer progression.

Cell Rep 2014 Apr 13;7(2):527-538. Epub 2014 Apr 13.

Division of Refractory Cancer Research, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.027DOI Listing
April 2014

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.

Cancer Discov 2014 Mar 20;4(3):292-303. Epub 2013 Dec 20.

1Genes and Cancer Group, Cancer Epigenetics and Biology Program (PEBC); 2Translational Research Laboratory, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona; 3Instituto de Biomedicina de Sevilla (IBiS), 4Department of Pathology, Hospital Universitario Virgen del Rocío, Consejo Superior de Investigaciones Cientificas (CSIC), Universidad de Sevilla, Seville; 5Division of Oncology, Centro para la Investigación Medica Aplicada (CIMA), University of Navarre, Pamplona, Spain; 6MRC-Holland, Amsterdam, the Netherlands; and 7Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0799DOI Listing
March 2014

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer.

Genes Chromosomes Cancer 2013 Sep 28;52(9):802-16. Epub 2013 May 28.

Division of Multistep Carcinogenesis, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1002/gcc.22076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806277PMC
September 2013

Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer.

Cancer Genet 2013 Mar 9;206(3):73-80. Epub 2013 Mar 9.

Department of Medical Biology, School of Medicine, Pamukkale University, Denizli, Turkey.

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http://dx.doi.org/10.1016/j.cancergen.2013.01.005DOI Listing
March 2013

Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma.

Genes Chromosomes Cancer 2012 May 3;51(5):462-72. Epub 2012 Feb 3.

Division of Multistep Carcinogenesis, National Cancer Center Research Institute, Tokyo, Japan.

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http://doi.wiley.com/10.1002/gcc.21933
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http://dx.doi.org/10.1002/gcc.21933DOI Listing
May 2012

MYC amplification as a prognostic marker of early-stage lung adenocarcinoma identified by whole genome copy number analysis.

Clin Cancer Res 2011 Mar 10;17(6):1481-9. Epub 2010 Dec 10.

Biology Division, National Cancer Center Research Institute; Cancer Genomics Project, The University of Tokyo, Tokyo, Japan.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-10-2484DOI Listing
March 2011

Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of human lung cancer cells.

Lung Cancer 2010 Nov 5;70(2):136-45. Epub 2010 Mar 5.

Biology Division, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2010.02.004DOI Listing
November 2010

Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.

Cancer Sci 2010 Aug 19;101(8):1891-6. Epub 2010 May 19.

Division of Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01622.xDOI Listing
August 2010

A gene-alteration profile of human lung cancer cell lines.

Hum Mutat 2009 Aug;30(8):1199-206

Lung Cancer Group, Molecular Pathology Programme, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.

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http://dx.doi.org/10.1002/humu.21028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900846PMC
August 2009

Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas.

Cancer Res 2009 Feb 3;69(4):1615-23. Epub 2009 Feb 3.

Biology Division, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3218DOI Listing
February 2009

Frequent EGFR mutations in brain metastases of lung adenocarcinoma.

Int J Cancer 2006 Sep;119(6):1491-4

Biology Division, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1002/ijc.21940DOI Listing
September 2006

Frequent EGFR mutations in noninvasive bronchioloalveolar carcinoma.

Int J Cancer 2006 May;118(10):2498-504

Biology Division, National Cancer Center Research Institute, Tokyo, and Division of Medical Oncology and Molecular Respirology, Faculty of Medicine, Tottori University, Japan.

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http://dx.doi.org/10.1002/ijc.21670DOI Listing
May 2006