Reijo Sironen

Reijo Sironen

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Reijo Sironen

Reijo Sironen

Publications by authors named "Reijo Sironen"

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Topical cis-urocanic acid prevents ocular surface irritation in both IgE -independent and -mediated rat model.

Graefes Arch Clin Exp Ophthalmol 2017 Dec 24;255(12):2357-2362. Epub 2017 Aug 24.

BioCis Pharma Ltd, Turku, Finland.

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http://dx.doi.org/10.1007/s00417-017-3781-zDOI Listing
December 2017

Incidentally detected enhancing lesions found in breast MRI: analysis of apparent diffusion coefficient and T2 signal intensity significantly improves specificity.

Eur Radiol 2016 Dec 25;26(12):4361-4370. Epub 2016 Apr 25.

Kuopio University Hospital, Diagnostic Imaging Centre, Department of Clinical Radiology, Kuopio University Hospital, PO Box 1777, Puijonlaaksontie 2, 70210, Kuopio, Finland.

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http://dx.doi.org/10.1007/s00330-016-4326-2DOI Listing
December 2016

Mesotheliomas show higher hyaluronan positivity around tumor cells than metastatic pulmonary adenocarcinomas.

Histol Histopathol 2016 Oct 25;31(10):1113-22. Epub 2016 Feb 25.

Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.14670/HH-11-740DOI Listing
October 2016

Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis.

Biogerontology 2016 08 28;17(4):749-61. Epub 2016 Apr 28.

Department of Ophthalmology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1007/s10522-016-9647-7DOI Listing
August 2016

Diffusion-Weighted Imaging in 3.0 Tesla Breast MRI: Diagnostic Performance and Tumor Characterization Using Small Subregions vs. Whole Tumor Regions of Interest.

PLoS One 2015 12;10(10):e0138702. Epub 2015 Oct 12.

Kuopio University Hospital, Diagnostic Imaging Centre, Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland; University of Eastern Finland, Institute of Clinical Medicine, School of Medicine, Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland; University of Eastern Finland, Cancer Center of Eastern Finland, Kuopio, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138702PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601774PMC
June 2016

Low numbers of tryptase+ and chymase+ mast cells associated with reduced survival and advanced tumor stage in melanoma.

Melanoma Res 2015 Dec;25(6):479-85

aDepartment of Dermatology bInstitute of Biomedicine/Anatomy cInstitute of Clinical Medicine/Clinical Pathology dCancer Center of Eastern Finland, University of Eastern Finland eCancer Center fDepartment of Clinical Pathology gDepartment of Dermatology, Kuopio University Hospital, Kuopio, Finland.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CMR.0000000000000192DOI Listing
December 2015

Contrast-enhanced ultrasound -guided axillary lymph node core biopsy: Diagnostic accuracy in preoperative staging of invasive breast cancer.

Eur J Radiol 2015 Nov 18;84(11):2130-6. Epub 2015 Aug 18.

Department of Clinical Radiology, Kuopio University Hospital, Kuopio, P.O. Box 100, Puijonlaaksontie 2, 70029 KYS, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X153007
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http://dx.doi.org/10.1016/j.ejrad.2015.08.006DOI Listing
November 2015

SIP1 predicts progression and poor prognosis in pharyngeal squamous cell carcinoma.

Histol Histopathol 2015 May 21;30(5):569-79. Epub 2014 Nov 21.

Department of Otorhinolaryngology- Head and Neck Surgery, Kuopio University Hospital, and Institute of Clinical Medicine, Otorhinolaryngology- Head and Neck Surgery, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.14670/HH-30.569DOI Listing
May 2015

Decreased hyaluronidase 1 expression is associated with early disease recurrence in human endometrial cancer.

Gynecol Oncol 2015 Apr 10;137(1):152-9. Epub 2015 Jan 10.

Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland; Biocenter Kuopio and Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland; Imaging Center, Clinical Pathology, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1016/j.ygyno.2015.01.525DOI Listing
April 2015

Enhanced polyamine catabolism disturbs hematopoietic lineage commitment and leads to a myeloproliferative disease in mice overexpressing spermidine/spermine N¹-acetyltransferase.

Amino Acids 2014 Mar 9;46(3):689-700. Epub 2013 Jul 9.

Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, Biocenter Kuopio, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland.

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http://dx.doi.org/10.1007/s00726-013-1546-5DOI Listing
March 2014

Systemic overexpression of antizyme 1 in mouse reduces ornithine decarboxylase activity without major changes in tissue polyamine homeostasis.

Transgenic Res 2014 Feb 31;23(1):153-63. Epub 2013 Oct 31.

Institute of Biomedicine, University of Eastern Finland, P.O.B 1627, 70211, Kuopio, Finland,

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http://link.springer.com/10.1007/s11248-013-9763-y
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http://dx.doi.org/10.1007/s11248-013-9763-yDOI Listing
February 2014

Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival.

Breast Cancer Res Treat 2014 Jan 14;143(2):277-86. Epub 2013 Dec 14.

Department of Oncology, Cancer Center, Kuopio University Hospital, P.O. Box 100, 70029, Kuopio, Finland,

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http://dx.doi.org/10.1007/s10549-013-2804-7DOI Listing
January 2014

Matriptase-2 gene (TMPRSS6) variants associate with breast cancer survival, and reduced expression is related to triple-negative breast cancer.

Int J Cancer 2013 Nov 4;133(10):2334-40. Epub 2013 Jun 4.

Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland; Biocenter Kuopio and Cancer Center of Easter Finland, University of Eastern Finland, Kuopio, Finland; Imaging Center, Clinical Pathology, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1002/ijc.28254DOI Listing
November 2013

Axillary lymph node biopsy in newly diagnosed invasive breast cancer: comparative accuracy of fine-needle aspiration biopsy versus core-needle biopsy.

Radiology 2013 Oct 14;269(1):54-60. Epub 2013 Jun 14.

Departments of Clinical Radiology, Surgery, and Clinical Pathology, Kuopio University Hospital, PO Box 1777, Puijonlaaksontie 2, 70210 Kuopio, Finland; Units of Radiology and Pathology and Forensic Medicine at Institute of Clinical Medicine, Biocenter Kuopio, and Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1148/radiol.13122637DOI Listing
October 2013

Increased hyaluronan content and stromal cell CD44 associate with HER2 positivity and poor prognosis in human breast cancer.

Int J Cancer 2013 Feb 20;132(3):531-9. Epub 2012 Jul 20.

Department of Oncology, Cancer Center, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1002/ijc.27707DOI Listing
February 2013

Lipopolysaccharide-induced anti-inflammatory acute phase response is enhanced in spermidine/spermine N1-acetyltransferase (SSAT) overexpressing mice.

Amino Acids 2012 Feb 4;42(2-3):473-84. Epub 2011 Aug 4.

Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, Biocenter Kuopio, University of Eastern Finland, P. O. Box 1627, 70211, Kuopio, Finland.

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http://link.springer.com/10.1007/s00726-011-1026-8
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http://dx.doi.org/10.1007/s00726-011-1026-8DOI Listing
February 2012

Overexpression of spermidine/spermine N1-acetyltransferase or treatment with N1-N11-diethylnorspermine attenuates the severity of zinc-induced pancreatitis in mouse.

Amino Acids 2012 Feb 4;42(2-3):461-71. Epub 2011 Aug 4.

Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, Biocenter Kuopio, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.

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http://link.springer.com/10.1007/s00726-011-1025-9
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http://dx.doi.org/10.1007/s00726-011-1025-9DOI Listing
February 2012

Transcription factor snail1 expression and poor survival in pharyngeal squamous cell carcinoma.

Histol Histopathol 2011 04;26(4):443-9

Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.14670/HH-26.443DOI Listing
April 2011

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.

Authors:
Xiaohong R Yang Jenny Chang-Claude Ellen L Goode Fergus J Couch Heli Nevanlinna Roger L Milne Mia Gaudet Marjanka K Schmidt Annegien Broeks Angela Cox Peter A Fasching Rebecca Hein Amanda B Spurdle Fiona Blows Kristy Driver Dieter Flesch-Janys Judith Heinz Peter Sinn Alina Vrieling Tuomas Heikkinen Kristiina Aittomäki Päivi Heikkilä Carl Blomqvist Jolanta Lissowska Beata Peplonska Stephen Chanock Jonine Figueroa Louise Brinton Per Hall Kamila Czene Keith Humphreys Hatef Darabi Jianjun Liu Laura J Van 't Veer Flora E van Leeuwen Irene L Andrulis Gord Glendon Julia A Knight Anna Marie Mulligan Frances P O'Malley Nayana Weerasooriya Esther M John Matthias W Beckmann Arndt Hartmann Sebastian B Weihbrecht David L Wachter Sebastian M Jud Christian R Loehberg Laura Baglietto Dallas R English Graham G Giles Catriona A McLean Gianluca Severi Diether Lambrechts Thijs Vandorpe Caroline Weltens Robert Paridaens Ann Smeets Patrick Neven Hans Wildiers Xianshu Wang Janet E Olson Victoria Cafourek Zachary Fredericksen Matthew Kosel Celine Vachon Helen E Cramp Daniel Connley Simon S Cross Sabapathy P Balasubramanian Malcolm W R Reed Thilo Dörk Michael Bremer Andreas Meyer Johann H Karstens Aysun Ay Tjoung-Won Park-Simon Peter Hillemanns Jose Ignacio Arias Pérez Primitiva Menéndez Rodríguez Pilar Zamora Javier Benítez Yon-Dschun Ko Hans-Peter Fischer Ute Hamann Beate Pesch Thomas Brüning Christina Justenhoven Hiltrud Brauch Diana M Eccles William J Tapper Sue M Gerty Elinor J Sawyer Ian P Tomlinson Angela Jones Michael Kerin Nicola Miller Niall McInerney Hoda Anton-Culver Argyrios Ziogas Chen-Yang Shen Chia-Ni Hsiung Pei-Ei Wu Show-Lin Yang Jyh-Cherng Yu Shou-Tung Chen Giu-Cheng Hsu Christopher A Haiman Brian E Henderson Loic Le Marchand Laurence N Kolonel Annika Lindblom Sara Margolin Anna Jakubowska Jan Lubiński Tomasz Huzarski Tomasz Byrski Bohdan Górski Jacek Gronwald Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Agnes Jager Mieke Kriege Madeleine M A Tilanus-Linthorst Margriet Collée Shan Wang-Gohrke Katri Pylkäs Arja Jukkola-Vuorinen Kari Mononen Mervi Grip Pasi Hirvikoski Robert Winqvist Arto Mannermaa Veli-Matti Kosma Jaana Kauppinen Vesa Kataja Päivi Auvinen Ylermi Soini Reijo Sironen Stig E Bojesen David Dynnes Ørsted Diljit Kaur-Knudsen Henrik Flyger Børge G Nordestgaard Helene Holland Georgia Chenevix-Trench Siranoush Manoukian Monica Barile Paolo Radice Susan E Hankinson David J Hunter Rulla Tamimi Suleeporn Sangrajrang Paul Brennan James McKay Fabrice Odefrey Valerie Gaborieau Peter Devilee P E A Huijts R A E M Tollenaar C Seynaeve Gillian S Dite Carmel Apicella John L Hopper Fleur Hammet Helen Tsimiklis Letitia D Smith Melissa C Southey Manjeet K Humphreys Douglas Easton Paul Pharoah Mark E Sherman Montserrat Garcia-Closas

J Natl Cancer Inst 2011 Feb 29;103(3):250-63. Epub 2010 Dec 29.

Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Sciences, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1093/jnci/djq526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107570PMC
February 2011

Transcription factors zeb1, twist and snai1 in breast carcinoma.

BMC Cancer 2011 Feb 16;11:73. Epub 2011 Feb 16.

Department of Pathology and Forensic Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, School of Medicine, University of Eastern Finland, Cancer Center of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland.

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http://dx.doi.org/10.1186/1471-2407-11-73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055233PMC
February 2011

ST14 gene variant and decreased matriptase protein expression predict poor breast cancer survival.

Cancer Epidemiol Biomarkers Prev 2010 Sep 17;19(9):2133-42. Epub 2010 Aug 17.

Department of Pathology, Institute of Clinical Medicine, School of Medicine, University of Eastern Finland and Kuopio University Hospital, Biocenter Kuopio, Finland.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-0418DOI Listing
September 2010

Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma.

BMC Cancer 2010 Sep 27;10:512. Epub 2010 Sep 27.

Institute of Clinical Medicine, Department of Pathology and Forensic Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1186/1471-2407-10-512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956733PMC
September 2010

Prognostic significance of matrix metalloproteinase-7 in epithelial ovarian cancer and its relation to beta-catenin expression.

Int J Cancer 2006 Oct;119(8):1792-9

Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Kuopio, Kuopio, Finland.

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http://dx.doi.org/10.1002/ijc.22067DOI Listing
October 2006

Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells.

Brain Res Mol Brain Res 2005 Jun 7;137(1-2):126-31. Epub 2005 Apr 7.

Department of Ophthalmology, University of Kuopio, P.O. BOX 1627, 70211 Kuopio, Finland.

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http://dx.doi.org/10.1016/j.molbrainres.2005.02.027DOI Listing
June 2005

High hydrostatic pressure inhibits the biosynthesis of eukaryotic elongation factor-2.

J Cell Biochem 2005 Feb;94(3):497-507

Department of Anatomy, University of Kuopio, 70211 Kuopio, Finland.

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http://dx.doi.org/10.1002/jcb.20333DOI Listing
February 2005

Hydrostatic pressure-induced changes in cellular protein synthesis.

Biorheology 2004 ;41(3-4):309-13

Department of Anatomy, University of Kuopio, Kuopio, Finland.

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December 2004

Reticulon 4 in chondrocytic cells: barosensitivity and intracellular localization.

Int J Biochem Cell Biol 2004 Aug;36(8):1521-31

Department of Anatomy, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.

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http://dx.doi.org/10.1016/j.biocel.2004.01.001DOI Listing
August 2004

Stress responses of mammalian cells to high hydrostatic pressure.

Biorheology 2003 ;40(1-3):87-92

Department of Anatomy, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.

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March 2003

Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study.

Biorheology 2003 ;40(1-3):93-100

Department of Anatomy, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.

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March 2003

Specific induction of heat shock protein 90beta by high hydrostatic pressure.

Biorheology 2003 ;40(1-3):141-6

Department of Anatomy, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.

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March 2003

High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis.

Biorheology 2002 ;39(1-2):111-7

Department of Anatomy, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.

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October 2002

cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure.

Biochim Biophys Acta 2002 Aug;1591(1-3):45-54

Department of Anatomy, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.

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http://dx.doi.org/10.1016/s0167-4889(02)00247-1DOI Listing
August 2002