Publications by authors named "Regina Feederle"

76Publications

Loss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice.

Int J Cancer 2020 Dec 26;147(11):3224-3235. Epub 2020 Aug 26.

Laboratory of Biochemistry and Molecular Biology, Department of Medical Technology, Faculty of Medicine, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1002/ijc.33262DOI Listing
December 2020

Spt6 is a maintenance factor for centromeric CENP-A.

Nat Commun 2020 06 10;11(1):2919. Epub 2020 Jun 10.

Wellcome Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, EH9 3BF, UK.

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http://dx.doi.org/10.1038/s41467-020-16695-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287101PMC
June 2020

A family of hyperpolarization-activated channels selective for protons.

Proc Natl Acad Sci U S A 2020 06 28;117(24):13783-13791. Epub 2020 May 28.

Department of Molecular Sensory Systems, Research Center Caesar, 53175 Bonn, Germany;

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http://dx.doi.org/10.1073/pnas.2001214117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306766PMC
June 2020

Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.

EMBO Rep 2019 03 7;20(3):e46451. Epub 2019 Feb 7.

Institute for Metabolic Biochemistry, Biomedical Center (BMC), Ludwig-Maximilians University Munich, Munich, Germany.

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http://dx.doi.org/10.15252/embr.201846451DOI Listing
March 2019

Aβ43-producing PS1 FAD mutants cause altered substrate interactions and respond to γ-secretase modulation.

EMBO Rep 2020 01 25;21(1):e47996. Epub 2019 Nov 25.

Biomedical Center (BMC), Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.15252/embr.201947996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945062PMC
January 2020

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells.

Cell Rep 2019 10;29(4):873-888.e10

Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology, Helmholtz-Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.09.040DOI Listing
October 2019

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.

PLoS Biol 2019 01 29;17(1):e2006767. Epub 2019 Jan 29.

Vertebrate DNA Replication Lab, Centre for Medical Biotechnology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1371/journal.pbio.2006767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377148PMC
January 2019

Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes.

Cell Rep 2018 12;25(13):3618-3630.e6

Institute of Human Genetics, Universitätsklinikum Heinrich-Heine-Universität Düsseldorf, Universität Str. 1, 40225 Düsseldorf, Germany; Center for Molecular Medicine Cologne, University of Cologne, Robert-Koch-Str. 21, 50931 Cologne, Germany; IUF-Leibniz-Institut für umweltmedizinische Forschung gGmbH, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183190
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http://dx.doi.org/10.1016/j.celrep.2018.11.102DOI Listing
December 2018

Determination of enrichment factors for modified RNA in MeRIP experiments.

Methods 2019 03 28;156:102-109. Epub 2018 Oct 28.

Institute of Pharmacy and Biochemistry, Johannes Gutenberg-University Mainz, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10462023183030
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http://dx.doi.org/10.1016/j.ymeth.2018.10.020DOI Listing
March 2019

Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes.

Cell Rep 2018 09;24(12):3339-3352

Institute for Molecular Biology and Tumor Research (IMT), Philipps-University Marburg, Hans-Meerwein-Strasse 2, BMFZ, 35043 Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.08.052DOI Listing
September 2018

Interactions, localization, and phosphorylation of the mA generating METTL3-METTL14-WTAP complex.

RNA 2018 04 18;24(4):499-512. Epub 2018 Jan 18.

Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1261/rna.064063.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855951PMC
April 2018

Double-Cone Localization and Seasonal Expression Pattern Suggest a Role in Magnetoreception for European Robin Cryptochrome 4.

Curr Biol 2018 01 4;28(2):211-223.e4. Epub 2018 Jan 4.

Institut für Biologie und Umweltwissenschaften, Carl-von-Ossietzky-Universität Oldenburg, Carl-von-Ossietzky-Strasse 9-11, 26129 Oldenburg, Germany; Research Centre for Neurosensory Sciences, Carl-von-Ossietzky-Universität Oldenburg, Carl-von-Ossietzky-Strasse 9-11, 26129 Oldenburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.12.003DOI Listing
January 2018

T cell specific Cxcr5 deficiency prevents rheumatoid arthritis.

Sci Rep 2017 08 21;7(1):8933. Epub 2017 Aug 21.

Institute of Immunology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1038/s41598-017-08935-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567121PMC
August 2017

Antibodies specific for nucleic acid modifications.

RNA Biol 2017 09 23;14(9):1089-1098. Epub 2017 Feb 23.

a Monoclonal Antibody Core Facility and Research Group, Institute for Diabetes and Obesity , Helmholtz Zentrum München, German Research Center for Environmental Health GmbH , München , Germany.

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http://dx.doi.org/10.1080/15476286.2017.1295905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699546PMC
September 2017

Generation of Pax1/PAX1-Specific Monoclonal Antibodies.

Monoclon Antib Immunodiagn Immunother 2016 10 5;35(5):259-262. Epub 2016 Oct 5.

3 Institute of Genetic Medicine, Newcastle University , International Centre for Life, Newcastle upon Tyne, United Kingdom .

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http://dx.doi.org/10.1089/mab.2016.0029DOI Listing
October 2016

Immunological Characterization of Intraocular Lymphoid Follicles in a Spontaneous Recurrent Uveitis Model.

Invest Ophthalmol Vis Sci 2016 08;57(10):4504-11

Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munich, München, Germany 5Experimental Ophthalmology, Philipps University of Marburg, Marburg, Germany.

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http://dx.doi.org/10.1167/iovs.16-19787DOI Listing
August 2016

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.

EMBO Mol Med 2016 09 1;8(9):992-1004. Epub 2016 Sep 1.

Biomedical Center (BMC), Biochemistry, Ludwig-Maximilians-University Munich, Munich, Germany Munich Cluster for Systems Neurology (SyNergy), Munich, Germany German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany

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http://embomolmed.embopress.org/lookup/doi/10.15252/emmm.201
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http://dx.doi.org/10.15252/emmm.201606370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009806PMC
September 2016

A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog.

PLoS Pathog 2016 Jan 22;12(1):e1005405. Epub 2016 Jan 22.

Pathogenesis of Virus Associated Tumors, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1005405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723338PMC
January 2016

The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation.

Nucleic Acids Res 2016 Feb 3;44(3):1326-41. Epub 2015 Dec 3.

Pathogenesis of Virus Associated Tumors, German Cancer Research Center, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany Inserm unit U1074, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1093/nar/gkv1330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756819PMC
February 2016

Epstein-Barr Virus: From the Detection of Sequence Polymorphisms to the Recognition of Viral Types.

Curr Top Microbiol Immunol 2015 ;390(Pt 1):119-48

Unit F100, Inserm unit U1074, DKFZ, German Cancer Research Centre (DKFZ), 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-3-319-22822-8_7DOI Listing
March 2016

Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4+ T cells.

Blood 2015 Mar 7;125(10):1601-10. Epub 2015 Jan 7.

German Cancer Research Centre (DKFZ) Unit F100, Heidelberg, Germany; Institut National de la Santé et de la Recherche Médicale Unit U1074, Heidelberg, Germany; German Centre for Infection Research (DZIF), Heidelberg, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-07-59
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http://dx.doi.org/10.1182/blood-2014-07-591412DOI Listing
March 2015

Genetics of Epstein-Barr virus microRNAs.

Semin Cancer Biol 2014 Jun 3;26:52-9. Epub 2014 Mar 3.

German Cancer Research Centre (DKFZ), Unit F100, 69120 Heidelberg, Germany; Inserm Unit U1074, DKFZ, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2014.02.002DOI Listing
June 2014

Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas.

Cell Rep 2013 Oct 10;5(2):458-70. Epub 2013 Oct 10.

German Cancer Research Centre (DKFZ), Unit F100, 69120 Heidelberg, Germany; Inserm Unit U1074, DKFZ, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.celrep.2013.09.012DOI Listing
October 2013

The viral and cellular microRNA targetome in lymphoblastoid cell lines.

PLoS Pathog 2012 Jan 26;8(1):e1002484. Epub 2012 Jan 26.

Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266933PMC
January 2012

Epstein-Barr virus genetics: talking about the BAC generation.

Herpesviridae 2010 Dec 7;1(1). Epub 2010 Dec 7.

German Cancer Research Centre, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.

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http://herpesviridae.biomedcentral.com/articles/10.1186/2042
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http://dx.doi.org/10.1186/2042-4280-1-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063228PMC
December 2010

Epstein-Barr viruses that express a CD21 antibody provide evidence that gp350's functions extend beyond B-cell surface binding.

J Virol 2010 Jan 4;84(2):1139-47. Epub 2009 Nov 4.

German Cancer Research Center, ATV-F100, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1128/JVI.01953-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798361PMC
January 2010

Expression and processing of a small nucleolar RNA from the Epstein-Barr virus genome.

PLoS Pathog 2009 Aug 14;5(8):e1000547. Epub 2009 Aug 14.

Innsbruck Biocenter, Division of Genomics and RNomics, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1371/journal.ppat.1000547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718842PMC
August 2009

Contribution of viral recombinants to the study of the immune response against the Epstein-Barr virus.

Semin Cancer Biol 2008 Dec 30;18(6):409-15. Epub 2008 Sep 30.

German Cancer Research Center, Department of Virus Associated Tumours, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2008.09.001DOI Listing
December 2008

Standardized and highly efficient expansion of Epstein-Barr virus-specific CD4+ T cells by using virus-like particles.

J Virol 2008 Apr 13;82(8):3903-11. Epub 2008 Feb 13.

Children's Hospital, University of Technology, Kölner Platz 1, D-80804 Munich, Germany.

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http://dx.doi.org/10.1128/JVI.02227-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2293016PMC
April 2008

Epstein-Barr virus-induced B-cell transformation: quantitating events from virus binding to cell outgrowth.

J Gen Virol 2005 Nov;86(Pt 11):3009-3019

German Cancer Centre, Department of Virus Associated Tumours, Im Neuenheimer Feld 242, D-69120 Heidelberg, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.81153-0DOI Listing
November 2005

Efficient somatic gene targeting in the lymphoid human cell line DG75.

Gene 2004 Dec;343(1):91-7

Department of Gene Vectors, GSF-National Research Center for Environment and Health, Marchioninistr. 25, Munich D-81377, Germany.

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http://dx.doi.org/10.1016/j.gene.2004.08.005DOI Listing
December 2004

The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold.

Proc Natl Acad Sci U S A 2003 Sep 28;100(19):10989-94. Epub 2003 Aug 28.

Department of Gene Vectors, GSF-National Research Center for Environment and Health, Marchioninistrasse 25, 81377 Munich, Germany.

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http://dx.doi.org/10.1073/pnas.1832776100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC196914PMC
September 2003