Reecha Sofat

Reecha Sofat

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Reecha Sofat

Reecha Sofat

Publications by authors named "Reecha Sofat"

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Drug and therapeutics committees as guardians of safe and rational medicines use.

Br J Clin Pharmacol 2019 Oct 18. Epub 2019 Oct 18.

Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1111/bcp.14088DOI Listing
October 2019

A novel approach to support implementation of biosimilars within a UK tertiary hospital.

Br J Clin Pharmacol 2019 Oct 29. Epub 2019 Oct 29.

University College London Hospital, London, UK.

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http://dx.doi.org/10.1111/bcp.14150DOI Listing
October 2019

24-Hour vs. Spot Urinary Sodium and Potassium Measurements in Adult Hypertensive Patients: A Cohort Validation Study.

Am J Hypertens 2019 Sep;32(10):983-991

Complex Hypertension Service, UCL Department of Renal Medicine, University College London, London, UK.

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http://dx.doi.org/10.1093/ajh/hpz104DOI Listing
September 2019

Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study.

Lancet 2019 08 25;394(10199):663-671. Epub 2019 Jul 25.

Department of Non-Communicable Diseases Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Health Data Research UK, London, UK.

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http://dx.doi.org/10.1016/S0140-6736(19)31359-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717081PMC
August 2019

Resistant Hypertension: Trials and Tribulations.

Hypertension 2018 05 2;71(5):772-780. Epub 2018 Apr 2.

From the Department of Clinical Pharmacology, University College London Hospital NHS Foundation Trust, United Kingdom (M.J.G., R.S., J.M., A.H.); Centre for Molecular Medicine, University College London, United Kingdom (D.J.B.M.); Nephrology, Royal Free London NHS Foundation Trust, United Kingdom (T.R.); Silver Creek Pharmaceuticals, San Francisco, CA (R.B.); Dorset County Hospital, Dorchester, United Kingdom (R.M.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom (R.M.T.); Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (J.A.S.); Hadassah-Hebrew University Medical Center, Mount-Scopus, Jerusalem, Israel (M.B.); Department of Nephrology, Galway University Hospitals, Ireland (D.L.); and University Paris Descartes, AP-HP, Hypertension Unit, Hospital European Georges Pompidou, France (M.B.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.10864DOI Listing
May 2018

Association of C-Reactive Protein Genetic Polymorphisms With Late Age-Related Macular Degeneration.

JAMA Ophthalmol 2017 09;135(9):909-916

Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, England.

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http://dx.doi.org/10.1001/jamaophthalmol.2017.2191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710541PMC
September 2017

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

Circulation 2017 Jun 12;135(24):2373-2388. Epub 2017 May 12.

From Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, United Kingdom (C.E.D., G.F., D.P.-M., A.D.H., J.P.C.); Department of Mathematics and Statistics, Lancaster University, United Kingdom (T.M.P.); UCLGenetics Institute, University College London, United Kingdom (J.W.); Applied Statistical Methods in Medical Research Group, Universidad Catolica de San Antonio de Murcia, Spain (D.P.-M.); Social Genetic & Developmental Psychiatry, King's College London, United Kingdom (D.Z.); Institute of Cardiovascular Science, University College London, United Kingdom (J.E.L.E., T.S., A.D.H., S.E.H.); MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom (A.W., D.K.); Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (S.M., J.F.P.); Department of Cardiology, Leiden University Medical Center, The Netherlands (S.T., W.J.); South Australian Health and Medical Research Institute, Adelaide (M.M., E.H.); EMBL Australia, Adelaide (M.M.); School of Social and Community Medicine, University of Bristol, United Kingdom (R.W.M., T.R.G., Y.B.-S., D.A.L., G.D.S.); Centre for Clinical Pharmacology, University College London, United Kingdom (R.S.); Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom (M.K.); Centre for Population Health Research, School of Health Sciences and Sansom Institute, University of South Australia, Adelaide (E.H., A.Z.); Population, Policy & Practice, UCL Great Ormond Street Institute of Child Health, London, United Kingdom (E.H., C.P.); Department of Primary Care & Population Health, University College London, Royal Free Campus, United Kingdom (B.J.J.); MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (T.R.G., D.A.L., G.D.S.); Department of Women's Cancer, Institute for Women's Health, UCL, London, United Kingdom (A.G.-M., A.R., U.M.); Department of Clinical Epidemiology, Leiden University Medical Center, The Netherlands (R.d.M., D.O.M.-K.); Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands (R.N., S.T.); Interuniversity Cardiology Institute Netherlands, Utrecht (W.J.); Departments of Neurology and Public Health Sciences, University of Virginia, Charlottesville (B.B.W.); Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands (D.O.M.-K.); BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, United Kingdom (N.S.); Department of Epidemiology and Public Health, University College London, United Kingdom (M.K.); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom (F.D.); Department of Health Sciences, University of Leicester, United Kingdom (F.D.); Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute Building, University of Oxford, United Kingdom (M.V.H.); Medical Research Council Population Health Research Unit at the University of Oxford, United Kingdom (M.V.H.); and National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals, United Kingdom (M.V.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515354PMC
June 2017

Cross-talk between iNKT cells and monocytes triggers an atheroprotective immune response in SLE patients with asymptomatic plaque.

Sci Immunol 2016 Dec;1(6)

Centre for Rheumatology Research, Department of Medicine, University College London, Rayne Building, London W1CE 6JF, U.K.

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http://dx.doi.org/10.1126/sciimmunol.aah4081DOI Listing
December 2016

Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies.

PLoS Med 2016 Oct 18;13(10):e1002146. Epub 2016 Oct 18.

Farr Institute of Health Informatics, Faculty of Population Health Sciences, University College London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068709PMC
October 2016

Mendelian randomization of blood lipids for coronary heart disease.

Eur Heart J 2015 Mar 27;36(9):539-50. Epub 2014 Jan 27.

Genetic Epidemiology Group, Institute of Cardiovacular Science, Faculty of Population Healh Sciences, University College London, 1-19 Torrington Place, London WC1E 6BT, UK Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

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https://eurheartj.oxfordjournals.org/content/ehj/36/9/539.fu
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http://eurheartj.oxfordjournals.org/cgi/doi/10.1093/eurheart
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http://dx.doi.org/10.1093/eurheartj/eht571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344957PMC
March 2015

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Authors:
Daniel I Swerdlow David Preiss Karoline B Kuchenbaecker Michael V Holmes Jorgen E L Engmann Tina Shah Reecha Sofat Stefan Stender Paul C D Johnson Robert A Scott Maarten Leusink Niek Verweij Stephen J Sharp Yiran Guo Claudia Giambartolomei Christina Chung Anne Peasey Antoinette Amuzu KaWah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos Yun R Li Gordon Lowe John Gallacher Marlene C W Stewart Ioanna Tzoulaki Sarah G Buxbaum Daphne L van der A Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Urszula Stepaniak Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Fabrizio Veglia Ian Ford J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Pim A de Jong Ale Algra Wilko Spiering Anke H Maitland-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Charles B Eaton Jennifer G Robinson David Duggan John Kjekshus John R Downs Antonio M Gotto Anthony C Keech Roberto Marchioli Gianni Tognoni Peter S Sever Neil R Poulter David D Waters Terje R Pedersen Pierre Amarenco Haruo Nakamura John J V McMurray James D Lewsey Daniel I Chasman Paul M Ridker Aldo P Maggioni Luigi Tavazzi Kausik K Ray Sreenivasa Rao Kondapally Seshasai JoAnn E Manson Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Pamela J Schreiner Myriam Fornage David S Siscovick Mary Cushman Meena Kumari Nick J Wareham W M Monique Verschuren Susan Redline Sanjay R Patel John C Whittaker Anders Hamsten Joseph A Delaney Caroline Dale Tom R Gaunt Andrew Wong Diana Kuh Rebecca Hardy Sekar Kathiresan Berta A Castillo Pim van der Harst Eric J Brunner Anne Tybjaerg-Hansen Michael G Marmot Ronald M Krauss Michael Tsai Josef Coresh Ronald C Hoogeveen Bruce M Psaty Leslie A Lange Hakon Hakonarson Frank Dudbridge Steve E Humphries Philippa J Talmud Mika Kivimäki Nicholas J Timpson Claudia Langenberg Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Alex P Reiner Brendan J Keating Aroon D Hingorani Naveed Sattar

Lancet 2015 Jan 24;385(9965):351-61. Epub 2014 Sep 24.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1016/S0140-6736(14)61183-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322187PMC
January 2015

Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials.

Br J Clin Pharmacol 2013 Nov;76(5):649-67

Genetic Epidemiology Group, Department of Epidemiology & Public Health, Division of Population Health, University College London, London, WC1E 6BT, UK; Department of Pharmacy, Royal National Orthopaedic Hospital, Middlesex, HA7 4LP, UK.

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http://dx.doi.org/10.1111/bcp.12083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853525PMC
November 2013

Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.

Neurology 2013 Jun;80(23):2154-65

Department of Brain Repair and Rehabilitation, Institute of Neurology, Centre for Clinical Pharmacology, University College London, London, UK.

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http://dx.doi.org/10.1212/WNL.0b013e318295d751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716358PMC
June 2013

Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay.

J Immunol Methods 2013 Apr 30;390(1-2):63-73. Epub 2013 Jan 30.

Centre for Clinical Pharmacology, Division of Medicine, University College London, Rayne Building, 5 University Street, London, WC1E 6JJ, UK.

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http://dx.doi.org/10.1016/j.jim.2013.01.009DOI Listing
April 2013

Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.

Circ Cardiovasc Genet 2013 Apr 16;6(2):163-70. Epub 2013 Mar 16.

Genetic Epidemiology Group, Research Department of Epidemiology and Public Health, UCL Institute of Epidemiology & Health Care, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGENETICS.112.964254DOI Listing
April 2013

Complex disease genetics: present and future translational applications.

Genome Med 2009 5;1(11):104. Epub 2009 Nov 5.

Centre for Clinical Pharmacology, Division of Medicine, University College London, Rayne Institute, 5 University Street, London, WC1E 6JJ, UK.

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http://dx.doi.org/10.1186/gm104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808739PMC
October 2012

Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease?

Eur Heart J 2012 Sep 5;33(18):2258-64. Epub 2012 Jul 5.

Genetic Epidemiology Group, Research Department of Epidemiology and Public Health, Division of Population Health, University College London, Torrington Place, London WC1E 6BT, UK.

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http://dx.doi.org/10.1093/eurheartj/ehs168DOI Listing
September 2012

Association of a sequence variant in DAB2IP with coronary heart disease.

Eur Heart J 2012 Apr 28;33(7):881-8. Epub 2011 Mar 28.

BHF Laboratories, Department of Medicine, Centre for Cardiovascular Genetics, University College London (UCL), The Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://eurheartj.oxfordjournals.org/content/ehj/early/2011/0
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http://eurheartj.oxfordjournals.org/cgi/doi/10.1093/eurheart
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http://dx.doi.org/10.1093/eurheartj/ehr075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345557PMC
April 2012

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:
Daniel I Swerdlow Michael V Holmes Karoline B Kuchenbaecker Jorgen E L Engmann Tina Shah Reecha Sofat Yiran Guo Christina Chung Anne Peasey Roman Pfister Simon P Mooijaart Helen A Ireland Maarten Leusink Claudia Langenberg Ka Wah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos John Hardy Michael A Nalls Yun Rose Li Gordon Lowe Marlene Stewart Suzette J Bielinski Julian Peto Nicholas J Timpson John Gallacher Malcolm Dunlop Richard Houlston Ian Tomlinson Ioanna Tzoulaki Jian'an Luan Jolanda M A Boer Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Luigi Ferrucci Stefania Bandenelli Toshiko Tanaka James F Meschia Andrew Singleton Gerjan Navis Irene Mateo Leach Stephan J L Bakker Ron T Gansevoort Ian Ford Stephen E Epstein Mary Susan Burnett Joe M Devaney J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Yolanda van der Graaf Pim A de Jong Anke-Hilse Mailand-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Jeffrey W Stephens Charles B Eaton Jennifer G Robinson JoAnn E Manson F Gerry Fowkes Timonthy M Frayling Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Susan Redline Leslie A Lange Meena Kumari Nick J Wareham W M Monique Verschuren Emelia J Benjamin John C Whittaker Anders Hamsten Frank Dudbridge J A Chris Delaney Andrew Wong Diana Kuh Rebecca Hardy Berta Almoguera Castillo John J Connolly Pim van der Harst Eric J Brunner Michael G Marmot Christina L Wassel Steve E Humphries Philippa J Talmud Mika Kivimaki Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Hakon Hakonarson Alex P Reiner Brendan J Keating Naveed Sattar Aroon D Hingorani Juan Pablo Casas

Lancet 2012 Mar 14;379(9822):1214-24. Epub 2012 Mar 14.

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http://dx.doi.org/10.1016/S0140-6736(12)60110-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316968PMC
March 2012

Could NICE guidance on the choice of blood pressure lowering drugs be simplified?

BMJ 2012 Jan 13;344:d8078. Epub 2012 Jan 13.

Centre for Clinical Pharmacology, University College London, London WC1E 6JJ, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957318PMC
http://dx.doi.org/10.1136/bmj.d8078DOI Listing
January 2012

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.

Atherosclerosis 2010 Nov 29;213(1):184-90. Epub 2010 Jul 29.

Centre for Clinical Pharmacology, Division of Medicine, University College London, Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.07.021DOI Listing
November 2010

Translating genomics into improved healthcare.

BMJ 2010 Nov 5;341:c5945. Epub 2010 Nov 5.

Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957319PMC
http://dx.doi.org/10.1136/bmj.c5945DOI Listing
November 2010

An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism.

Invest Ophthalmol Vis Sci 2010 May 30;51(5):2393-402. Epub 2009 Dec 30.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.09-4228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868481PMC
May 2010

A report on the Genetics of Complex Diseases meeting of the British Atherosclerosis Society, Cambridge, UK, 17-18 September 2009.

Atherosclerosis 2010 Feb 26;208(2):599-602. Epub 2009 Nov 26.

Genetic Epidemiology Research Group, UCL Research Department of Epidemiology and Public Health, University College London, 1 - 19 Torrington Place, London, WC1E 6BT, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.11.034DOI Listing
February 2010