Publications by authors named "Rebecca S Levin"

Publications

Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells.

Authors:
Garry L Coles Sandra Cristea James T Webber Rebecca S Levin Steven M Moss Andy He Jaya Sangodkar Yeonjoo C Hwang Julia Arand Alexandros P Drainas Nancie A Mooney Janos Demeter Jessica N Spradlin Brandon Mauch Vicky Le Yan Ting Shue Julie H Ko Myung Chang Lee Christina Kong Daniel K Nomura Michael Ohlmeyer Danielle L Swaney Nevan J Krogan Peter K Jackson Goutham Narla John D Gordan Kevan M Shokat Julien Sage

Cancer Cell 2020 Jul 11;38(1):129-143.e7. Epub 2020 Jun 11.

Department of Pediatrics, Stanford University, 265 Campus Drive, Stanford, CA 94305-5457, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address:

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July 2020

Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex.

Authors:
Sara Hernández-Ortega Abril Sánchez-Botet Eva Quandt Núria Masip Laura Gasa Gaetano Verde Javier Jiménez Rebecca S Levin Florentine U Rutaganira Alma L Burlingame Don Wolfgeher Mariana P C Ribeiro Stephen J Kron Kevan M Shokat Josep Clotet

Exp Mol Med 2019 04 16;51(4):1-17. Epub 2019 Apr 16.

Faculty of Medicine and Health Sciences, International University of Catalonia, 08195, Sant Cugat del Vallès, Barcelona, Spain.

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April 2019

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer.

Authors:
Hayley J Donnella James T Webber Rebecca S Levin Roman Camarda Olga Momcilovic Nora Bayani Khyati N Shah James E Korkola Kevan M Shokat Andrei Goga John D Gordan Sourav Bandyopadhyay

Nat Chem Biol 2018 08 25;14(8):768-777. Epub 2018 Jun 25.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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August 2018

An Optimized Chromatographic Strategy for Multiplexing In Parallel Reaction Monitoring Mass Spectrometry: Insights from Quantitation of Activated Kinases.

Authors:
Anatoly Urisman Rebecca S Levin John D Gordan James T Webber Hilda Hernandez Yasushi Ishihama Kevan M Shokat Alma L Burlingame

Mol Cell Proteomics 2017 02 11;16(2):265-277. Epub 2016 Dec 11.

§Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California.

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February 2017

Discovery of new substrates of the elongation factor-2 kinase suggests a broader role in the cellular nutrient response.

Authors:
Michael B Lazarus Rebecca S Levin Kevan M Shokat

Cell Signal 2017 01 17;29:78-83. Epub 2016 Oct 17.

Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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January 2017

Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen.

Authors:
Rebecca S Levin Nicholas T Hertz Alma L Burlingame Kevan M Shokat Shaeri Mukherjee

Proc Natl Acad Sci U S A 2016 08 1;113(33):E4776-83. Epub 2016 Aug 1.

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143

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August 2016

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib.

Authors:
Rowan E Miller Rachel Brough Ilirjana Bajrami Chris T Williamson Simon McDade James Campbell Asha Kigozi Rumana Rafiq Helen Pemberton Rachel Natrajan Josephine Joel Holly Astley Claire Mahoney Jonathan D Moore Chris Torrance John D Gordan James T Webber Rebecca S Levin Kevan M Shokat Sourav Bandyopadhyay Christopher J Lord Alan Ashworth

Mol Cancer Ther 2016 07 30;15(7):1472-84. Epub 2016 Jun 30.

The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, United Kingdom. Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom.

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July 2016

Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma.

Authors:
Supriya K Saha John D Gordan Benjamin P Kleinstiver Phuong Vu Mortada S Najem Jia-Chi Yeo Lei Shi Yasutaka Kato Rebecca S Levin James T Webber Leah J Damon Regina K Egan Patricia Greninger Ultan McDermott Mathew J Garnett Roger L Jenkins Kimberly M Rieger-Christ Travis B Sullivan Aram F Hezel Andrew S Liss Yusuke Mizukami Lipika Goyal Cristina R Ferrone Andrew X Zhu J Keith Joung Kevan M Shokat Cyril H Benes Nabeel Bardeesy

Cancer Discov 2016 07 26;6(7):727-39. Epub 2016 May 26.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts.

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July 2016

P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.

Authors:
Miriam Sansó Rebecca S Levin Jesse J Lipp Vivien Ya-Fan Wang Ann Katrin Greifenberg Elizabeth M Quezada Akbar Ali Animesh Ghosh Stéphane Larochelle Tariq M Rana Matthias Geyer Liang Tong Kevan M Shokat Robert P Fisher

Genes Dev 2016 Jan;30(1):117-31

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;

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January 2016

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.

Authors:
Bethany E Schaffer Rebecca S Levin Nicholas T Hertz Travis J Maures Michael L Schoof Pablo E Hollstein Bérénice A Benayoun Max R Banko Reuben J Shaw Kevan M Shokat Anne Brunet

Cell Metab 2015 Nov 8;22(5):907-21. Epub 2015 Oct 8.

Cancer Biology Program, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford, CA 94305, USA. Electronic address:

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November 2015

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Authors:
Maria M Martins Alicia Y Zhou Alexandra Corella Dai Horiuchi Christina Yau Taha Rakhshandehroo John D Gordan Rebecca S Levin Jeff Johnson John Jascur Mike Shales Antonio Sorrentino Jaime Cheah Paul A Clemons Alykhan F Shamji Stuart L Schreiber Nevan J Krogan Kevan M Shokat Frank McCormick Andrei Goga Sourav Bandyopadhyay

Cancer Discov 2015 02 12;5(2):154-67. Epub 2014 Dec 12.

University of California, San Francisco, San Francisco, California.

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February 2015

Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.

Authors:
Martin L Sos Rebecca S Levin John D Gordan Juan A Oses-Prieto James T Webber Megan Salt Byron Hann Alma L Burlingame Frank McCormick Sourav Bandyopadhyay Kevan M Shokat

Cell Rep 2014 Aug 7;8(4):1037-48. Epub 2014 Aug 7.

Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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August 2014

Global turnover of histone post-translational modifications and variants in human cells.

Authors:
Barry M Zee Rebecca S Levin Peter A DiMaggio Benjamin A Garcia

Epigenetics Chromatin 2010 Dec 6;3(1):22. Epub 2010 Dec 6.

Department of Molecular Biology, Princeton University, Princeton NJ, 08544, USA.

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December 2010

In vivo residue-specific histone methylation dynamics.

Authors:
Barry M Zee Rebecca S Levin Bo Xu Gary LeRoy Ned S Wingreen Benjamin A Garcia

J Biol Chem 2010 Jan 23;285(5):3341-50. Epub 2009 Nov 23.

Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.

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January 2010