Publications by authors named "Rebecca Howard"

45Publications

Shared structural mechanisms of general anaesthetics and benzodiazepines.

Nature 2020 09 2;585(7824):303-308. Epub 2020 Sep 2.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1038/s41586-020-2654-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486282PMC
September 2020

Imprecision nutrition? Different simultaneous continuous glucose monitors provide discordant meal rankings for incremental postprandial glucose in subjects without diabetes.

Am J Clin Nutr 2020 Aug 7. Epub 2020 Aug 7.

National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.

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http://dx.doi.org/10.1093/ajcn/nqaa198DOI Listing
August 2020

Rape Kit Notification: Recommendations and Barriers to Reconnecting with Survivors.

J Trauma Dissociation 2020 Jul-Sep;21(4):419-436

Department of Psychology, California State University at Long Beach ., Long Beach, California, USA.

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http://dx.doi.org/10.1080/15299732.2020.1770911DOI Listing
June 2020

Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.

Proc Natl Acad Sci U S A 2020 06 1;117(24):13437-13446. Epub 2020 Jun 1.

Unité Dynamique Structurale des Macromolécules, Institut Pasteur, UMR 3528, CNRS, 75015 Paris, France;

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http://dx.doi.org/10.1073/pnas.1922701117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306758PMC
June 2020

Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor.

Neuron 2019 11 2;104(3):501-511.e6. Epub 2019 Sep 2.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.07.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842111PMC
November 2019

Online Machine Learning Audiometry.

Ear Hear 2019 Jul/Aug;40(4):918-926

Laboratory of Sensory Neuroscience and Neuroengineering, Department of Biomedical Engineering, Washington University in St. Louis, Missouri, USA.

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http://Insights.ovid.com/crossref?an=00003446-900000000-9886
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http://dx.doi.org/10.1097/AUD.0000000000000669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476703PMC
January 2020

Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity.

Proc Natl Acad Sci U S A 2018 10 1;115(42):10672-10677. Epub 2018 Oct 1.

Department of Biochemistry and Biophysics, Stockholm University, 11419 Stockholm, Sweden;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1809650115
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http://dx.doi.org/10.1073/pnas.1809650115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196478PMC
October 2018

Sexual violence victimization among community college students.

J Am Coll Health 2019 Oct 26;67(7):674-687. Epub 2018 Sep 26.

Prevention Innovations Research Center, University of New Hampshire , Durham , New Hampshire , USA.

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https://www.tandfonline.com/doi/full/10.1080/07448481.2018.1
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http://dx.doi.org/10.1080/07448481.2018.1500474DOI Listing
October 2019

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.

Cell Rep 2018 04;23(4):993-1004

Unit of Structural Dynamics of Macromolecules, Institut Pasteur and UMR 3528 du CNRS, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.108DOI Listing
April 2018

Long-term impacts of college sexual assaults on women survivors' educational and career attainments.

J Am Coll Health 2018 Aug-Sep;66(6):496-507. Epub 2018 Mar 30.

a Prevention Innovations Research Center, University of New Hampshire , Durham , New Hampshire , USA.

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http://dx.doi.org/10.1080/07448481.2018.1440574DOI Listing
September 2019

Evolution of IgE responses to multiple allergen components throughout childhood.

J Allergy Clin Immunol 2018 10 9;142(4):1322-1330. Epub 2018 Feb 9.

Section of Paediatrics, Department of Medicine, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170973PMC
October 2018

A feasible model for early intervention for high-risk substance use in the emergency department setting.

Aust Health Rev 2019 Apr;43(2):188-193

Department of Addiction Medicine, St Vincent's Hospital Melbourne, 41 Victoria Parade, Fitzroy, Vic. 3065, Australia.

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http://dx.doi.org/10.1071/AH17148DOI Listing
April 2019

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.

Biochim Biophys Acta Biomembr 2018 Apr 16;1860(4):927-942. Epub 2017 Dec 16.

Department of Medical Genetics and Molecular Biochemistry, Temple University Lewis Katz School of Medicine, Philadelphia, PA 19140, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2017.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317864PMC
April 2018

Distinguishing Asthma Phenotypes Using Machine Learning Approaches.

Curr Allergy Asthma Rep 2015 Jul;15(7):38

Centre for Health Informatics, Institute of Population Health, University of Manchester, Manchester, UK.

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http://link.springer.com/content/pdf/10.1007/s11882-015-0542
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http://link.springer.com/10.1007/s11882-015-0542-0
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http://dx.doi.org/10.1007/s11882-015-0542-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586004PMC
July 2015

Synthesis and use of universal sequence probes in fluorogenic multi-strand hybridisation complexes for economical nucleic acid testing.

Mol Cell Probes 2015 Aug 14;29(4):228-36. Epub 2015 May 14.

LGC, Queens Road, Teddington TW11 0LY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mcp.2015.05.007DOI Listing
August 2015

Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors.

Alcohol Clin Exp Res 2015 Jun 14;39(6):962-8. Epub 2015 May 14.

Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas.

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http://dx.doi.org/10.1111/acer.12735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452391PMC
June 2015

Factors associated with re-presentation to emergency departments in elderly people with pain.

Aust Health Rev 2014 Sep;38(4):461-6

Emergency Practice Innovation Centre (EPIC), St Vincent's Hospital Melbourne, 41 Victoria Parade, Fitzroy, Vic. 3065, Australia.

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http://dx.doi.org/10.1071/AH13233DOI Listing
September 2014

Effects of disturbance associated with seismic exploration for oil and gas reserves in coastal marshes.

Environ Manage 2014 Jul 1;54(1):30-50. Epub 2014 May 1.

U.S. Geological Survey, National Wetlands Research Center, 700 Cajundome Blvd., Lafayette, LA, 70506, USA,

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http://dx.doi.org/10.1007/s00267-014-0274-2DOI Listing
July 2014

Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics.

Pharmacol Rev 2014 10;66(2):396-412. Epub 2014 Feb 10.

Department of Chemistry, Skidmore College, Saratoga Springs, NY 12866.

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http://dx.doi.org/10.1124/pr.113.007468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973611PMC
December 2014

Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels.

Mol Pharmacol 2013 Nov 15;84(5):670-8. Epub 2013 Aug 15.

Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland (S.A.H.); Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas (R.J.H., C.M.B., M.A.C., U.S.L., R.A.H.); Science for Life Laboratory, KTH Royal Institute of Technology and Stockholm University, Stockholm, Sweden (T.B., E.L.); and Department of Biochemistry and Biophysics, Center for Biomembrane Research, Science for Life Laboratory, Stockholm University, Stockholm, Sweden (J.C.).

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http://dx.doi.org/10.1124/mol.113.087692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807073PMC
November 2013

Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites.

Structure 2013 Aug 25;21(8):1307-16. Epub 2013 Jul 25.

Science for Life Laboratory, KTH Royal Institute of Technology & Stockholm University, 17121 Solna, Sweden.

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http://dx.doi.org/10.1016/j.str.2013.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787718PMC
August 2013

Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).

J Biol Chem 2013 Mar 30;288(12):8355-64. Epub 2013 Jan 30.

Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, PB 601, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1074/jbc.M112.424507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605653PMC
March 2013

Molecular mechanism for the dual alcohol modulation of Cys-loop receptors.

PLoS Comput Biol 2012 4;8(10):e1002710. Epub 2012 Oct 4.

Science for Life Laboratory, KTH Royal Institute of Technology & Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pcbi.1002710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464191PMC
May 2013

The TM2 6' position of GABA(A) receptors mediates alcohol inhibition.

J Pharmacol Exp Ther 2012 Feb 9;340(2):445-56. Epub 2011 Nov 9.

Waggoner Center for Alcohol and Addiction Research, University of Texas, 1 University Station A4800, Austin, TX 78712-05159, USA.

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http://dx.doi.org/10.1124/jpet.111.188037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263960PMC
February 2012

Structural basis for alcohol modulation of a pentameric ligand-gated ion channel.

Proc Natl Acad Sci U S A 2011 Jul 5;108(29):12149-54. Epub 2011 Jul 5.

Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1104480108
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http://dx.doi.org/10.1073/pnas.1104480108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141919PMC
July 2011

Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution.

Alcohol Clin Exp Res 2011 Sep 15;35(9):1561-73. Epub 2011 Jun 15.

Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Texas 77812, USA.

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http://dx.doi.org/10.1111/j.1530-0277.2011.01502.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201783PMC
September 2011

Rapid typing of STRs in the human genome by HyBeacon melting.

Org Biomol Chem 2008 Dec 30;6(24):4553-9. Epub 2008 Oct 30.

School of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK.

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http://www.rsc.org/suppdata/ob/b8/b813431f/b813431f.pdf
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http://xlink.rsc.org/?DOI=b813431f
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http://dx.doi.org/10.1039/b813431fDOI Listing
December 2008

Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation.

BMC Cell Biol 2007 Jul 30;8:32. Epub 2007 Jul 30.

Department of Biological Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, USA.

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http://dx.doi.org/10.1186/1471-2121-8-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952058PMC
July 2007

Structural insight into KCNQ (Kv7) channel assembly and channelopathy.

Neuron 2007 Mar;53(5):663-75

Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, CA 94158-2330, USA.

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http://dx.doi.org/10.1016/j.neuron.2007.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011230PMC
March 2007

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.

Mol Cell 2003 Dec;12(6):1427-37

Departments of Structural Biology and Genetics/Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/s1097-2765(03)00452-0DOI Listing
December 2003

Pelvic umbrella pack for refractory obstetric hemorrhage secondary to posterior uterine rupture.

Obstet Gynecol 2002 Nov;100(5 Pt 2):1061-3

Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA.

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http://dx.doi.org/10.1016/s0029-7844(02)02016-1DOI Listing
November 2002