Rebecca Fransson

Rebecca Fransson

UNVERIFIED PROFILE

Are you Rebecca Fransson?   Register this Author

Register author
Rebecca Fransson

Rebecca Fransson

Publications by authors named "Rebecca Fransson"

Are you Rebecca Fransson?   Register this Author

18Publications

141Reads

43Profile Views

Ranking in Vitro Dissolution of Inhaled Micronized Drug Powders including a Candidate Drug with Two Different Particle Sizes.

Mol Pharm 2018 11 22;15(11):5319-5326. Epub 2018 Oct 22.

Pharmaceutical Sciences, IMED , AstraZeneca R&D , Pepparedsleden 1 , Mölndal 43183 , Sweden.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.molpharmaceut.8b00796
Publisher Site
http://dx.doi.org/10.1021/acs.molpharmaceut.8b00796DOI Listing
November 2018

Bile salt enhancers for inhalation: Correlation between in vitro and in vivo lung effects.

Int J Pharm 2018 Oct 17;550(1-2):114-122. Epub 2018 Aug 17.

Early Product Development, Pharmaceutical Science, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpharm.2018.08.031DOI Listing
October 2018

An imidazole based H-Phe-Phe-NH peptidomimetic with anti-allodynic effect in spared nerve injury mice.

Bioorg Med Chem Lett 2018 08 15;28(14):2446-2450. Epub 2018 Jun 15.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden; The Beijer Laboratory, Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2018.06.009DOI Listing
August 2018

Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration.

Eur J Pharm Sci 2017 Nov 5;109:533-540. Epub 2017 Sep 5.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09280987173049
Publisher Site
http://dx.doi.org/10.1016/j.ejps.2017.09.007DOI Listing
November 2017

Importance of N- and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration.

Eur J Pharm Sci 2017 Aug 3;106:345-351. Epub 2017 Jun 3.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2017.06.004DOI Listing
August 2017

N-terminal truncations of substance P 1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats.

Eur J Pharmacol 2014 Sep 13;738:319-25. Epub 2014 Jun 13.

Department of Physiology and Pharmacology, Karolinska Institutet, Nanna Svartz väg 2, SE-171 77 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejphar.2014.05.060DOI Listing
September 2014

Aminocarbonylation of 4-iodo-1H-imidazoles with an amino acid amide nucleophile: synthesis of constrained H-Phe-Phe-NH2 analogues.

J Org Chem 2013 Dec 14;78(23):12251-6. Epub 2013 Nov 14.

Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala Biomedical Center, Uppsala University , P.O. Box 574, SE-751 23 Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo4020613DOI Listing
December 2013

Design, Synthesis, and Anti-leukemic Activity of Stereochemically Defined Constrained Analogs of FTY720 (Gilenya).

ACS Med Chem Lett 2013 Oct;4(10)

Department of Chemistry, Université de Montréal, PO Box 6128, Station Centre-Ville, Montréal, Que., H3C 3J7, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ml4002425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834958PMC
October 2013

Constrained H-Phe-Phe-NH2 analogues with high affinity to the substance P 1-7 binding site and with improved metabolic stability and cell permeability.

J Med Chem 2013 Jun 17;56(12):4953-65. Epub 2013 Jun 17.

Department of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm400209hDOI Listing
June 2013

The dipeptide Phe-Phe amide attenuates signs of hyperalgesia, allodynia and nociception in diabetic mice using a mechanism involving the sigma receptor system.

Mol Pain 2011 Oct 31;7:85. Epub 2011 Oct 31.

Department of Pathophysiology & Therapeutics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 4-41, Ebara 2-chome, Tokyo 142-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1744-8069-7-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225307PMC
October 2011

Microwave-assisted synthesis of Weinreb and MAP aryl amides via Pd-catalyzed Heck aminocarbonylation using Mo(CO)6 or W(CO)6.

J Org Chem 2011 Feb 13;76(3):978-81. Epub 2011 Jan 13.

Department of Medicinal Chemistry, Uppsala University, Sweden.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/jo102151u
Publisher Site
http://dx.doi.org/10.1021/jo102151uDOI Listing
February 2011

The effect of substance P1-7 amide on nociceptive threshold in diabetic mice.

Peptides 2011 Jan 8;32(1):93-8. Epub 2010 Oct 8.

Department of Pathophysiology & Therapeutics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 4-41, Ebara 2-chome, Shinagawa-ku, Tokyo 142-8501, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.peptides.2010.09.029DOI Listing
January 2011

Discovery of dipeptides with high affinity to the specific binding site for substance P1-7.

J Med Chem 2010 Mar;53(6):2383-9

Department of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm901352bDOI Listing
March 2010

The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.

Peptides 2009 Dec 15;30(12):2418-22. Epub 2009 Aug 15.

Department of Pharmaceutical Biosciences, Division of Biological Research on Drug Dependence, Uppsala University, S-751 24 Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.peptides.2009.08.009DOI Listing
December 2009

Small peptides mimicking substance P (1-7) and encompassing a C-terminal amide functionality.

Neuropeptides 2008 Feb;42(1):31-7

Department of Medicinal Chemistry, Uppsala University, P.O. Box 574, SE-751 23 Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.npep.2007.11.002DOI Listing
February 2008

Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.

Bioorg Med Chem 2007 Feb 6;15(3):1448-74. Epub 2006 Nov 6.

Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2006.11.003DOI Listing
February 2007