Rebecca A Betensky

Rebecca A Betensky

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Rebecca A Betensky

Rebecca A Betensky

Publications by authors named "Rebecca A Betensky"

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Transformation model estimation of survival under dependent truncation and independent censoring.

Stat Methods Med Res 2019 Dec 13;28(12):3785-3798. Epub 2018 Dec 13.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1177/0962280218817573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565507PMC
December 2019

The missing indicator approach for censored covariates subject to limit of detection in logistic regression models.

Ann Epidemiol 2019 Oct 13;38:57-64. Epub 2019 Aug 13.

Department of Biostatistics and Epidemiology, University of Massachusetts - Amherst, Amherst, MA. Electronic address:

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http://dx.doi.org/10.1016/j.annepidem.2019.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812630PMC
October 2019

New Guidelines for Statistical Reporting.

N Engl J Med 2019 10;381(16):1597

New School for Social Research, New York, NY.

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http://dx.doi.org/10.1056/NEJMc1911817DOI Listing
October 2019

Inverse probability weighting methods for Cox regression with right-truncated data.

Biometrics 2019 Oct 17. Epub 2019 Oct 17.

Department of Biostatistics, College of Global Public Health, New York, New York.

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http://dx.doi.org/10.1111/biom.13162DOI Listing
October 2019

Characteristics of Paid Malpractice Claims Among Resident Physicians From 2001-2015 in the United States.

Acad Med 2019 Oct 15. Epub 2019 Oct 15.

M. Glover is radiologist and assistant professor, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; ORCID: 0000-0002-5711-8937. G.W. McGee is a postdoctoral researcher, Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts; ORCID: 0000-0002-6133-9169. D.S. Wilkinson is a data scientist, National Practitioner Data Bank, Bureau of Health Workforce, Health Resources and Services Administration, Rockville, Maryland. H. Singh is the chief data and research officer, National Practitioner Data Bank, Bureau of Health Workforce, Health Resources and Services Administration, Rockville, Maryland. A. Bolick, was an MPH student at the Harvard T. H. Chan School of Public Health, Boston, Massachusetts, at the time this article was written. R.A. Betensky is professor, Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts. H.B. Harvey is a radiologist and assistant professor, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; ORCID: 0000-0001-9550-1876. D. Weinstein is vice president for graduate medical education, Partners Healthcare, and associate professor of medicine, Harvard Medical School, Boston, Massachusetts. A.C. Schaffer is associate physician, Department of Medicine, Brigham and Women's Hospital; assistant professor of medicine, Harvard Medical School; and senior clinical analytics specialist, Controlled Risk Insurance Company/Risk Management Foundation of the Harvard Medical Institutions, Boston, Massachusetts.

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http://dx.doi.org/10.1097/ACM.0000000000003039DOI Listing
October 2019

Serum Levels of 25-Hydroxyvitamin D at Diagnosis Are Not Associated with Overall Survival in Esophageal Adenocarcinoma.

Cancer Epidemiol Biomarkers Prev 2019 Aug 11;28(8):1379-1387. Epub 2019 Jun 11.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-1190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677623PMC
August 2019

Wide Range of Clinical Outcomes in Patients with Gliomatosis Cerebri Growth Pattern: A Clinical, Radiographic, and Histopathologic Study.

Oncologist 2019 Mar 10;24(3):402-413. Epub 2018 Aug 10.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA

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http://dx.doi.org/10.1634/theoncologist.2018-0086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519760PMC
March 2019

Targeted genotyping for the prediction of celiac disease autoimmunity development in patients with type 1 diabetes and their family members.

World J Diabetes 2019 Mar;10(3):189-199

Mucosal Immunology and Biology Research Center, Mass General Hospital for Children, Boston, MA 02115, United States.

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http://dx.doi.org/10.4239/wjd.v10.i3.189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422857PMC
March 2019

Opposing Roles of apolipoprotein E in aging and neurodegeneration.

Life Sci Alliance 2019 02 13;2(1). Epub 2019 Feb 13.

Alzheimer Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.26508/lsa.201900325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374993PMC
February 2019

Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms.

Alzheimers Dement 2019 01 19;15(1):65-75. Epub 2018 Sep 19.

Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Gerontology Research Unit, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435328PMC
January 2019

Threshold regression to accommodate a censored covariate.

Biometrics 2018 12 22;74(4):1261-1270. Epub 2018 Jun 22.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1111/biom.12922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321791PMC
December 2018

Correction: Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Mol Psychiatry 2018 Dec 11. Epub 2018 Dec 11.

Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41380-018-0323-yDOI Listing
December 2018

Permutation Tests for General Dependent Truncation.

Comput Stat Data Anal 2018 Dec 29;128:308-324. Epub 2018 Jul 29.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, U.S.A.

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http://dx.doi.org/10.1016/j.csda.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317381PMC
December 2018

Biomarker validation with an imperfect reference: Issues and bounds.

Stat Methods Med Res 2018 10 6;27(10):2933-2945. Epub 2017 Feb 6.

3 Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1177/0962280216689806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494007PMC
October 2018

PET staging of amyloidosis using striatum.

Alzheimers Dement 2018 10 21;14(10):1281-1292. Epub 2018 May 21.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, and the Martinos Center for Biomedical Imaging, Charlestown, MA, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jalz.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219621PMC
October 2018

Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain.

J Neurochem 2018 10 7;147(1):24-39. Epub 2018 Sep 7.

Alzheimer's disease Research Laboratory, Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1111/jnc.14469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181788PMC
October 2018

An optimal Wilcoxon-Mann-Whitney test of mortality and a continuous outcome.

Stat Methods Med Res 2018 08 29;27(8):2384-2400. Epub 2016 Dec 29.

4 Department of Biostatistics, Harvard T.H. Chan School of Public Health.

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http://dx.doi.org/10.1177/0962280216680524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393279PMC
August 2018

Multicrossover Randomized Controlled Trial Designs in Alzheimer Disease.

Ann Neurol 2018 08 29;84(2):168-175. Epub 2018 Aug 29.

Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA.

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http://dx.doi.org/10.1002/ana.25280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481185PMC
August 2018

Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Mol Psychiatry 2018 Aug 16. Epub 2018 Aug 16.

Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://www.nature.com/articles/s41380-018-0214-2
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http://dx.doi.org/10.1038/s41380-018-0214-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377864PMC
August 2018

Inverse probability weighted Cox regression for doubly truncated data.

Biometrics 2018 06 8;74(2):481-487. Epub 2017 Sep 8.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1111/biom.12771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843502PMC
June 2018

Integration of risk factors for Parkinson disease in 2 large longitudinal cohorts.

Neurology 2018 05 11;90(19):e1646-e1653. Epub 2018 Apr 11.

From the Departments of Epidemiology (I.Y.K., A.A.), Nutrition (É.J.O., K.C.H., A.A.), and Biostatistics (R.A.B.), Harvard T.H. Chan School of Public Health, Boston, MA; School of Public Health (É.J.O.), University College Cork, Ireland; Channing Division of Network Medicine (A.A.), Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Department of Nutritional Sciences (X.G.), The Pennsylvania State University, University Park; MassGeneral Institute for Neurodegenerative Disease (M.A.S.), Massachusetts General Hospital, Boston; The Institute for Aging Research (M.T.H.), Hebrew Senior Life, Boston; and Department of Medicine (M.T.H.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000005473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952970PMC
May 2018

Time-to-event data with time-varying biomarkers measured only at study entry, with applications to Alzheimer's disease.

Stat Med 2018 03 20;37(6):914-932. Epub 2017 Dec 20.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1002/sim.7547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801265PMC
March 2018

Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.

Proc Natl Acad Sci U S A 2018 02 22;115(6):E1289-E1298. Epub 2018 Jan 22.

Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129;

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http://dx.doi.org/10.1073/pnas.1710329115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819390PMC
February 2018

Association of cancer and Alzheimer's disease risk in a national cohort of veterans.

Alzheimers Dement 2017 Dec 12;13(12):1364-1370. Epub 2017 Jul 12.

Division of Aging, Brigham and Women's Hospital, Boston, MA, USA; Massachusetts Veterans Epidemiology and Resource Information Center (MAVERIC), VA Boston Healthcare System (VABHS), Jamaica Plain, MA, USA; Geriatric Research Education and Clinical Center, VABHS, Jamaica Plain, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743228PMC
December 2017

Correlation among baseline variables yields non-uniformity of p-values.

PLoS One 2017 8;12(9):e0184531. Epub 2017 Sep 8.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184531PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590981PMC
October 2017

Fluorodeoxyglucose metabolism associated with tau-amyloid interaction predicts memory decline.

Ann Neurol 2017 Apr 6;81(4):583-596. Epub 2017 Apr 6.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, and the Martinos Center for Biomedical Imaging, Charlestown, MA.

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http://dx.doi.org/10.1002/ana.24910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404378PMC
April 2017

Is this significant?

Ann Neurol 2017 03;81(3):344-347

Annals of Neurology.

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http://dx.doi.org/10.1002/ana.24868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983895PMC
March 2017

Decreased hippocampal metabolism in high-amyloid mild cognitive impairment.

Alzheimers Dement 2016 12 13;12(12):1288-1296. Epub 2016 Jul 13.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; The Martinos Center for Biomedical Imaging, Charlestown, MA, USA.

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http://dx.doi.org/10.1016/j.jalz.2016.06.2357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148703PMC
December 2016

A Concept-Wide Association Study of Clinical Notes to Discover New Predictors of Kidney Failure.

Clin J Am Soc Nephrol 2016 12 10;11(12):2150-2158. Epub 2016 Oct 10.

Department of Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.2215/CJN.02420316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142057PMC
December 2016

Comparison of Urine Output among Patients Treated with More Intensive Versus Less Intensive RRT: Results from the Acute Renal Failure Trial Network Study.

Clin J Am Soc Nephrol 2016 08 22;11(8):1335-42. Epub 2016 Jul 22.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.2215/CJN.10991015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974887PMC
August 2016

Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.

J Neuropathol Exp Neurol 2016 06 22;75(6):516-26. Epub 2016 Apr 22.

From the Department of Neurology of the University of Iowa Hospitals & Clinics, Iowa City, Iowa (AS-P); Department of Biostatistics and Epidemiology of the University of Massachusetts, Amherst, Massachusetts (JQ); Massachusetts General Hospital Biostatistics Center, Boston, Massachusetts (AM); Department of Biostatistics, University of Washington, Seattle, Washington (SEM); Department of Pathology, School of Medicine of the University of Washington, Seattle, Washington (TJM); C. S. Kubik Laboratory for Neuropathology of the Massachusetts General Hospital (MPF), Department of Neurology of the Massachusetts General Hospital, Boston, Massachusetts (BTH); Department of Biostatistics of the Harvard T. H. Chan School of Public Health, Boston, Massachusetts (RAB); and Massachusetts Alzheimer Disease Research Center, Charlestown, Massachusetts (MPF, RAB, BTH).

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http://dx.doi.org/10.1093/jnen/nlw026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250207PMC
June 2016

Linear Regression with a Randomly Censored Covariate: Application to an Alzheimer's Study.

J R Stat Soc Ser C Appl Stat 2017 27;66(2):313-328. Epub 2016 Jun 27.

Harvard T.H. Chan School of Public Health, Boston, USA.

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http://dx.doi.org/10.1111/rssc.12164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319605PMC
June 2016

Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.

Neurobiol Aging 2016 Apr 28;40:61-67. Epub 2015 Dec 28.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792089PMC
April 2016

Multiple Imputation of a Randomly Censored Covariate Improves Logistic Regression Analysis.

J Appl Stat 2016 16;43(15):2886-2896. Epub 2016 Mar 16.

Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047523PMC
http://dx.doi.org/10.1080/02664763.2016.1155110DOI Listing
March 2016

Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease.

Am J Pathol 2016 Feb 11;186(2):375-84. Epub 2015 Dec 11.

Massachusetts Alzheimer Disease Research Center, Massachusetts General Hospital, Charlestown, Massachusetts; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729270PMC
February 2016

Recognizing the problem of delayed entry in time-to-event studies: Better late than never for clinical neuroscientists.

Ann Neurol 2015 Dec 13;78(6):839-44. Epub 2015 Nov 13.

Department of Statistics, Hebrew University of Jerusalem, Jerusalem, Israel.

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http://doi.wiley.com/10.1002/ana.24538
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http://dx.doi.org/10.1002/ana.24538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502209PMC
December 2015

Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy.

Neurobiol Aging 2015 Nov 16;36(11):2963-2971. Epub 2015 Jul 16.

Department of Neurology, Alzheimer Research Unit, Massachusetts General Hospital, Charlestown, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609585PMC
November 2015

Research participant compensation: A matter of statistical inference as well as ethics.

Contemp Clin Trials 2015 Nov 31;45(Pt B):265-269. Epub 2015 Aug 31.

Department of Biostatistics, Harvard School of Public Health, 655 Huntington Ave., Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15517144153007
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http://dx.doi.org/10.1016/j.cct.2015.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674311PMC
November 2015

A Pairwise Naïve Bayes Approach to Bayesian Classification.

Intern J Pattern Recognit Artif Intell 2015 Oct 28;29(7). Epub 2015 Jul 28.

Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Building 2, 4th Floor, Boston, MA 02115, USA,

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http://dx.doi.org/10.1142/S0218001415500238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832935PMC
October 2015

Measures of follow-up in time-to-event studies: Why provide them and what should they be?

Clin Trials 2015 Aug 29;12(4):403-8. Epub 2015 May 29.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA

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http://dx.doi.org/10.1177/1740774515586176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506242PMC
August 2015

Computationally simple analysis of matched, outcome-based studies of ordinal disease states.

Stat Med 2015 Jul 22;34(17):2514-27. Epub 2015 Apr 22.

Brain Tumor Center, Massachusetts General Hospital, Boston, MA, U.S.A.

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http://dx.doi.org/10.1002/sim.6503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490001PMC
July 2015

Accuracy of digital versus conventional implant impressions.

Clin Oral Implants Res 2015 Jun 10;26(6):715-9. Epub 2014 Apr 10.

Department of Restorative Dentistry and Biomaterials Sciences, Harvard School of Dental Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1111/clr.12375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428303PMC
June 2015

APOEε2 is associated with milder clinical and pathological Alzheimer disease.

Ann Neurol 2015 Jun;77(6):917-29

Department of Neurology, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1002/ana.24369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447539PMC
June 2015

Power and sample size calculations for the Wilcoxon-Mann-Whitney test in the presence of death-censored observations.

Stat Med 2015 Feb 13;34(3):406-31. Epub 2014 Nov 13.

Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, U.S.A.

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http://dx.doi.org/10.1002/sim.6355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289456PMC
February 2015

Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma.

J Neurooncol 2015 Feb 20;121(3):557-63. Epub 2014 Nov 20.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Division of Hematology/Oncology, Department of Neurology, Massachusetts General Hospital Cancer Center, 55 Fruit Street, Yawkey 9E, Boston, MA, 02114, USA,

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http://link.springer.com/content/pdf/10.1007%2Fs11060-014-16
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http://link.springer.com/10.1007/s11060-014-1667-z
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http://dx.doi.org/10.1007/s11060-014-1667-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323868PMC
February 2015

Vandetanib plus sirolimus in adults with recurrent glioblastoma: results of a phase I and dose expansion cohort study.

J Neurooncol 2015 Feb 13;121(3):627-34. Epub 2014 Dec 13.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, Yawkey 9 East, 55 Fruit Street, Boston, MA, 02114, USA,

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http://dx.doi.org/10.1007/s11060-014-1680-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324090PMC
February 2015

Reductions in red blood cell 2,3-diphosphoglycerate concentration during continuous renal replacment therapy.

Clin J Am Soc Nephrol 2015 Jan 23;10(1):74-9. Epub 2014 Dec 23.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts;

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http://dx.doi.org/10.2215/CJN.02160214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284404PMC
January 2015

Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy.

PLoS One 2013 20;8(11):e80834. Epub 2013 Nov 20.

Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, Massachusetts, United States of America ; MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080834PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835324PMC
December 2014

Vandetanib plus sirolimus in adults with recurrent glioblastoma: results of a phase I and dose expansion cohort study.

J Neurooncol 2015 Feb 13;121(3):627-34. Epub 2014 Dec 13.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, Yawkey 9 East, 55 Fruit Street, Boston, MA, 02114, USA,

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http://dx.doi.org/10.1007/s11060-014-1680-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324090PMC
February 2015

Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals.

JAMA Neurol 2014 Nov;71(11):1379-85

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston4Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston5Center for Alzheimer Research and Treatment, Department of Neurology, Brigham a.

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http://dx.doi.org/10.1001/jamaneurol.2014.2031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293023PMC
November 2014

Hospital acquired pneumonia is linked to right hemispheric peri-insular stroke.

PLoS One 2013 7;8(8):e71141. Epub 2013 Aug 7.

Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737185PMC
August 2014

Computationally simple estimation and improved efficiency for special cases of double truncation.

Lifetime Data Anal 2014 Jul 18;20(3):335-54. Epub 2013 Dec 18.

Department of Biostatistics, Harvard School of Public Health, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s10985-013-9287-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058384PMC
July 2014

Tau pathology does not affect experience-driven single-neuron and network-wide Arc/Arg3.1 responses.

Acta Neuropathol Commun 2014 Jun 10;2:63. Epub 2014 Jun 10.

Alzheimer's Disease Research Laboratory, Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, MA, USA.

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http://dx.doi.org/10.1186/2051-5960-2-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229905PMC
June 2014

Eliminating bias due to censoring in Kendall's tau estimators for quasi-independence of truncation and failure.

Comput Stat Data Anal 2014 May;73:16-26

Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115.

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http://dx.doi.org/10.1016/j.csda.2013.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912250PMC
May 2014

Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease.

Neurology 2014 May 18;82(20):1760-7. Epub 2014 Apr 18.

From the Departments of Neurology (E.C.M., A.P.S., D.M.R., K.A.J., R.A.S.), Radiology (T.H., A.P.S., K.A.J., R.A.S.), and Psychiatry (A.P.S., A.W.), and the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology (K.A.J.), Massachusetts General Hospital, Harvard Medical School; the Department of Biostatistics (R.A.B.), Harvard School of Public Health, Boston; the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (T.H.), Massachusetts General Hospital, Charleston; and the Center for Alzheimer Research and Treatment, Department of Neurology (A.W., W.H., D.M.R., K.A.J., R.A.S.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000000431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035706PMC
May 2014

Mild to moderate Alzheimer dementia with insufficient neuropathological changes.

Ann Neurol 2014 Apr 8;75(4):597-601. Epub 2014 Apr 8.

Massachusetts Alzheimer Disease Research Center, Charlestown, MA; Department of Neurology, Massachusetts General Hospital, Boston, MA; Department of Neurology, University of Iowa Hospitals & Clinics, Iowa city, IA.

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http://dx.doi.org/10.1002/ana.24125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016558PMC
April 2014

Anatomic pattern of intracerebral hemorrhage expansion: relation to CT angiography spot sign and hematoma center.

Stroke 2014 Apr 6;45(4):1154-6. Epub 2014 Mar 6.

From the Hemorrhagic Stroke Research Program, Department of Neurology (G.B., A.D., H.B.B., P.F., A. Vashkevich, A.A., K.S., A. Viswanathan, M.E.G., S.M.G.), Division of Neuroradiology, Department of Radiology (J.M.R.), Department of Emergency Medicine (J.N.G.), and Division of Neurocritical Care and Emergency Neurology (J.R.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; Department of Biostatistics, Harvard School of Public Health, Boston, MA (R.A.B.); and Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Alberta, Canada (E.E.S.).

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http://dx.doi.org/10.1161/STROKEAHA.114.004844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984947PMC
April 2014

Assumptions regarding right censoring in the presence of left truncation.

Stat Probab Lett 2014 Apr;87:12-17

Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, U.S.A.

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http://dx.doi.org/10.1016/j.spl.2013.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964676PMC
April 2014

Variable selection and prediction using a nested, matched case-control study: Application to hospital acquired pneumonia in stroke patients.

Biometrics 2014 Mar 9;70(1):153-63. Epub 2013 Dec 9.

Division of Biostatistics and Epidemiology, University of Massachusetts, Amherst, Massachusetts 01003, U.S.A.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, U.S.A.

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http://dx.doi.org/10.1111/biom.12113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954429PMC
March 2014

Improved design of prodromal Alzheimer's disease trials through cohort enrichment and surrogate endpoints.

J Alzheimers Dis 2013 ;36(3):475-86

MGH BiostatisticsCenter, Massachusetts General Hospital, 50 Staniford St., Boston, MA 02114, USA.

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http://dx.doi.org/10.3233/JAD-122212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779898PMC
February 2014

Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center.

J Neuropathol Exp Neurol 2013 Dec;72(12):1182-92

From the Massachusetts Alzheimer Disease Research Center, Massachusetts General Hospital (AS-P, MPF, BTH); and Department of Biostatistics, Harvard School of Public Health (JQ, RAB), Boston; and Division of Biostatistics and Epidemiology, University of Massachusetts, Amherst (JQ), Massachusetts; and National Alzheimer Coordinating Center and Department of Epidemiology, University of Washington, Seattle, Washington (SEM).

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http://dx.doi.org/10.1097/NEN.0000000000000016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962953PMC
December 2013

Estimating the effect of emergency care on early survival after traffic crashes.

Accid Anal Prev 2013 Nov 2;60:141-7. Epub 2013 Sep 2.

Maine Medical Center, Department of Surgery, 887 Congress Street, Suite 210, Portland, ME 04102, United States; Maine Medical Center, Center for Outcomes Research and Evaluation, Portland, ME, United States; Harvard School of Public Health, Harvard Injury Control Research Center, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.aap.2013.08.019DOI Listing
November 2013

Primary leptomeningeal lymphoma: International Primary CNS Lymphoma Collaborative Group report.

Neurology 2013 Nov 9;81(19):1690-6. Epub 2013 Oct 9.

From the Massachusetts General Hospital (J.W.T., T.B., R.A.B.), Boston; Mayo Clinic (E.P.F., B.P.O.), Rochester, MN; Hadassah Hebrew University Medical Center (T.S.), Jerusalem, Israel; Memorial Sloan-Kettering (A.O., L.D.), New York, NY; Yale University (J.B.), New Haven, CT; Saitama Medical University (R.N.), Japan; Kings College Hospital (F.P.), London, UK; University of Washington (M.C.), Seattle; LOC National Expert Center (K.H.-X., A.G.-A.), APHP, UPMC, Pitie-Salpetriere, Paris; Centre Leon Berard (J.-Y.B.), Lyon, France; Campus Benjamin Franklin (A.K.), Charite Universitätsmedizin Berlin, Germany; Department of Biostatistics (R.A.B.), Harvard School of Public Health, Boston, MA; and University of Virginia (M.-B.S.L., D.S.), Charlottesville.

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http://dx.doi.org/10.1212/01.wnl.0000435302.02895.f3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812109PMC
November 2013

Molecular evolution of human adenoviruses.

Sci Rep 2013 ;3:1812

Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/srep01812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648800PMC
October 2013

Imperfect gold standards for biomarker evaluation.

Clin Trials 2013 Oct 3;10(5):696-700. Epub 2013 Sep 3.

aRenal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/1740774513497540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800226PMC
October 2013

Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models.

Acta Neuropathol 2013 Sep 2;126(3):353-64. Epub 2013 Jul 2.

Alzheimer Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 114, 16th St., Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1007/s00401-013-1145-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810119PMC
September 2013

Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease.

J Neuropathol Exp Neurol 2013 Jun;72(6):462-71

Mass General Institute for Neurodegenerative Disease, Massachusetts General Hospital, Massachusetts Alzheimer Disease Research Center, and Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1097/NEN.0b013e3182933788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661683PMC
June 2013

Calcineurin activation causes retinal ganglion cell degeneration.

Mol Vis 2012 29;18:2828-38. Epub 2012 Nov 29.

Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519372PMC
May 2013

Patients with celiac disease have a lower prevalence of non-insulin-dependent diabetes mellitus and metabolic syndrome.

Gastroenterology 2013 May 24;144(5):912-917.e1. Epub 2013 Jan 24.

Celiac Center, Department of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1053/j.gastro.2013.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755346PMC
May 2013

An analysis of adaptive design variations on the sequential parallel comparison design for clinical trials.

Clin Trials 2013 Apr 2;10(2):207-15. Epub 2013 Jan 2.

Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Harvard University, Boston, MA, USA.

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http://journals.sagepub.com/doi/10.1177/1740774512468806
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http://dx.doi.org/10.1177/1740774512468806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612388PMC
April 2013

Estimating time to disease progression comparing transition models and survival methods--an analysis of multiple sclerosis data.

Biometrics 2013 Mar 14;69(1):225-34. Epub 2013 Feb 14.

Department of Statistics, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1111/biom.12002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909474PMC
March 2013

Hazard regression models of early mortality in trauma centers.

J Am Coll Surg 2012 Dec 1;215(6):841-9. Epub 2012 Oct 1.

Department of Surgery, Maine Medical Center, 887 Congress St., Portland, ME 04102, USA.

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http://dx.doi.org/10.1016/j.jamcollsurg.2012.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790585PMC
December 2012

Orchestrated experience-driven Arc responses are disrupted in a mouse model of Alzheimer's disease.

Nat Neurosci 2012 Oct 26;15(10):1422-9. Epub 2012 Aug 26.

Alzheimer's Disease Research Laboratory, Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1038/nn.3199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458168PMC
October 2012

Identification of tissue contamination by polymorphic deletion probe fluorescence in situ hybridization.

Am J Surg Pathol 2012 Oct;36(10):1464-71

Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Harvard School of Public Health, Boston, MA 02114, USA.

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http://dx.doi.org/10.1097/PAS.0b013e31826247a2DOI Listing
October 2012

Corelease of dopamine and GABA by a retinal dopaminergic neuron.

J Neurosci 2012 Sep;32(38):13281-91

Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2213-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489011PMC
September 2012

Stable size distribution of amyloid plaques over the course of Alzheimer disease.

J Neuropathol Exp Neurol 2012 Aug;71(8):694-701

MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1097/NEN.0b013e31825e77deDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407299PMC
August 2012