Rays H Y Jiang

Rays H Y Jiang

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Rays H Y Jiang

Rays H Y Jiang

Publications by authors named "Rays H Y Jiang"

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An adaptable soft-mold embossing process for fabricating optically-accessible, microfeature-based culture systems and application toward liver stage antimalarial compound testing.

Lab Chip 2020 Mar;20(6):1124-1139

Center for Global Health and Infectious Diseases Research, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, USA. and Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA.

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http://dx.doi.org/10.1039/c9lc00921cDOI Listing
March 2020

A SLC6 transporter cloned from the lion's mane jellyfish (Cnidaria, Scyphozoa) is expressed in neurons.

PLoS One 2019 24;14(6):e0218806. Epub 2019 Jun 24.

Global and Planetary Health, College of Public Health, University of South Florida USF Genomics Program, Tampa, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218806PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590891PMC
February 2020

5-Aminolevulinate synthase catalysis: The catcher in heme biosynthesis.

Mol Genet Metab 2019 11 13;128(3):178-189. Epub 2019 Jun 13.

Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA; Department of Global Health, College of Public Health, University of South Florida, Tampa, FL 33612, USA; Department of Chemistry, College of Arts and Sciences, University of South Florida, Tampa, FL 33612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2019.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908770PMC
November 2019

Plasmodium vivax readiness to transmit: implication for malaria eradication.

BMC Syst Biol 2019 01 11;13(1). Epub 2019 Jan 11.

Department of Global Health (GH) & Center for Drug Discovery and Innovation (CDDI), College of Public Health, University of South Florida, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1186/s12918-018-0669-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330404PMC
January 2019

GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors.

Nat Commun 2018 12 4;9(1):5154. Epub 2018 Dec 4.

Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1038/s41467-018-07644-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279809PMC
December 2018

Altered expression of K13 disrupts DNA replication and repair in Plasmodium falciparum.

BMC Genomics 2018 Nov 29;19(1):849. Epub 2018 Nov 29.

Center for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, USA.

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http://dx.doi.org/10.1186/s12864-018-5207-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263542PMC
November 2018

In-depth phenotypic characterization of reticulocyte maturation using mass cytometry.

Blood Cells Mol Dis 2018 09 4;72:22-33. Epub 2018 Jul 4.

Center for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097872PMC
September 2018

Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host.

Sci Rep 2018 08 15;8(1):12183. Epub 2018 Aug 15.

Center for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, Florida, USA.

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http://dx.doi.org/10.1038/s41598-018-30713-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093925PMC
August 2018

Uncovering the essential genes of the human malaria parasite by saturation mutagenesis.

Science 2018 05;360(6388)

Center for Global Health and Infectious Diseases, Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Suite 404, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1126/science.aap7847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360947PMC
May 2018

Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum.

Cell 2017 Dec 9;171(7):1532-1544.e15. Epub 2017 Nov 9.

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK; Harvard T.H. Chan School of Public Health, Department of Immunology and Infectious Diseases, Boston, MA 02155, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733390PMC
December 2017

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony.

Nat Microbiol 2017 Feb 17;2:17017. Epub 2017 Feb 17.

Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 651 Huntington Avenue, FXB, Room 202, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nmicrobiol.2017.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328244PMC
February 2017

Subcellular and in-vivo Nano-Endoscopy.

Sci Rep 2016 10 3;6:34400. Epub 2016 Oct 3.

IBIS Lab, Department of Chemical and Biomedical Engineering, University of South Florida, Tampa, FL 33647, USA.

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http://dx.doi.org/10.1038/srep34400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046067PMC
October 2016

Phenotypic Screens Identify Parasite Genetic Factors Associated with Malarial Fever Response in Mutants.

mSphere 2016 Sep-Oct;1(5). Epub 2016 Oct 26.

Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, USA.

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http://dx.doi.org/10.1128/mSphere.00273-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082630PMC
October 2016

Punctuated chromatin states regulate Plasmodium falciparum antigenic variation at the intron and 2 kb upstream regions.

BMC Genomics 2016 08 18;17:652. Epub 2016 Aug 18.

Department of Global Health (GH) & Center for Drug Discovery and Innovation (CDDI), College of Public Health, University of South Florida, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1186/s12864-016-3005-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990864PMC
August 2016

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants.

Genome Res 2016 07 10;26(7):980-9. Epub 2016 May 10.

Malaria Programme, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire CB10 1SA, United Kingdom;

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http://dx.doi.org/10.1101/gr.200279.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937560PMC
July 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Phenotypic and molecular analysis of the effect of 20-hydroxyecdysone on the human filarial parasite Brugia malayi.

Int J Parasitol 2016 05 16;46(5-6):333-41. Epub 2016 Feb 16.

Department of Global Health, College of Public Health, University of South Florida, Tampa, FL 33612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpara.2016.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936774PMC
May 2016

Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite.

Nat Commun 2016 Apr 4;7:11187. Epub 2016 Apr 4.

Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ncomms11187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822025PMC
April 2016

Functional analysis of sirtuin genes in multiple Plasmodium falciparum strains.

PLoS One 2015 17;10(3):e0118865. Epub 2015 Mar 17.

Department of Immunology & Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118865PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364008PMC
February 2016

Shared elements of host-targeting pathways among apicomplexan parasites of differing lifestyles.

Cell Microbiol 2015 Nov 7;17(11):1618-39. Epub 2015 Jul 7.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1111/cmi.12460DOI Listing
November 2015

Parasite Calcineurin Regulates Host Cell Recognition and Attachment by Apicomplexans.

Cell Host Microbe 2015 Jul 25;18(1):49-60. Epub 2015 Jun 25.

Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506782PMC
July 2015

Mechanisms and evolution of virulence in oomycetes.

Annu Rev Phytopathol 2012 ;50:295-318

The Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1146/annurev-phyto-081211-172912DOI Listing
August 2014

Eukaryotic virulence determinants utilize phosphoinositides at the ER and host cell surface.

Trends Microbiol 2013 Mar 30;21(3):145-56. Epub 2013 Jan 30.

Department of Infectious Diseases and Immunology, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.tim.2012.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595378PMC
March 2013

Massively parallel sequencing technology in pathogenic microbes.

Methods Mol Biol 2012 ;835:271-94

Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.

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http://dx.doi.org/10.1007/978-1-61779-501-5_17DOI Listing
April 2012

A PIP Gets the plasmodium protein export pathway going.

Cell Host Microbe 2012 Feb;11(2):99-100

The Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S19313128120003
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http://dx.doi.org/10.1016/j.chom.2012.01.011DOI Listing
February 2012

Recognition of Phytophthora infestans Avr4 by potato R4 is triggered by C-terminal domains comprising W motifs.

Mol Plant Pathol 2009 Sep;10(5):611-20

Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.

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http://dx.doi.org/10.1111/j.1364-3703.2009.00556.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640270PMC
September 2009

Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans.

Authors:
Brian J Haas Sophien Kamoun Michael C Zody Rays H Y Jiang Robert E Handsaker Liliana M Cano Manfred Grabherr Chinnappa D Kodira Sylvain Raffaele Trudy Torto-Alalibo Tolga O Bozkurt Audrey M V Ah-Fong Lucia Alvarado Vicky L Anderson Miles R Armstrong Anna Avrova Laura Baxter Jim Beynon Petra C Boevink Stephanie R Bollmann Jorunn I B Bos Vincent Bulone Guohong Cai Cahid Cakir James C Carrington Megan Chawner Lucio Conti Stefano Costanzo Richard Ewan Noah Fahlgren Michael A Fischbach Johanna Fugelstad Eleanor M Gilroy Sante Gnerre Pamela J Green Laura J Grenville-Briggs John Griffith Niklaus J Grünwald Karolyn Horn Neil R Horner Chia-Hui Hu Edgar Huitema Dong-Hoon Jeong Alexandra M E Jones Jonathan D G Jones Richard W Jones Elinor K Karlsson Sridhara G Kunjeti Kurt Lamour Zhenyu Liu Lijun Ma Daniel Maclean Marcus C Chibucos Hayes McDonald Jessica McWalters Harold J G Meijer William Morgan Paul F Morris Carol A Munro Keith O'Neill Manuel Ospina-Giraldo Andrés Pinzón Leighton Pritchard Bernard Ramsahoye Qinghu Ren Silvia Restrepo Sourav Roy Ari Sadanandom Alon Savidor Sebastian Schornack David C Schwartz Ulrike D Schumann Ben Schwessinger Lauren Seyer Ted Sharpe Cristina Silvar Jing Song David J Studholme Sean Sykes Marco Thines Peter J I van de Vondervoort Vipaporn Phuntumart Stephan Wawra Rob Weide Joe Win Carolyn Young Shiguo Zhou William Fry Blake C Meyers Pieter van West Jean Ristaino Francine Govers Paul R J Birch Stephen C Whisson Howard S Judelson Chad Nusbaum

Nature 2009 Sep 9;461(7262):393-8. Epub 2009 Sep 9.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, USA.

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http://dx.doi.org/10.1038/nature08358DOI Listing
September 2009

RXLR-mediated entry of Phytophthora sojae effector Avr1b into soybean cells does not require pathogen-encoded machinery.

Plant Cell 2008 Jul 11;20(7):1930-47. Epub 2008 Jul 11.

Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

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http://www.plantcell.org/cgi/doi/10.1105/tpc.107.056093
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http://dx.doi.org/10.1105/tpc.107.056093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518231PMC
July 2008

RXLR effector reservoir in two Phytophthora species is dominated by a single rapidly evolving superfamily with more than 700 members.

Proc Natl Acad Sci U S A 2008 Mar 14;105(12):4874-9. Epub 2008 Mar 14.

Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1073/pnas.0709303105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290801PMC
March 2008

An integrated BAC and genome sequence physical map of Phytophthora sojae.

Mol Plant Microbe Interact 2006 Dec;19(12):1302-10

Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0477, USA.

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http://dx.doi.org/10.1094/MPMI-19-1302DOI Listing
December 2006

Comparative analysis of Phytophthora genes encoding secreted proteins reveals conserved synteny and lineage-specific gene duplications and deletions.

Mol Plant Microbe Interact 2006 Dec;19(12):1311-21

Laboratory of Phytopathology, Plant Sciences Group, Wageningen University, Binnenhaven 5, NL-6709 PD Wageningen, The Netherlands.

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http://dx.doi.org/10.1094/MPMI-19-1311DOI Listing
December 2006

Nonneutral GC3 and retroelement codon mimicry in Phytophthora.

J Mol Evol 2006 Oct 4;63(4):458-72. Epub 2006 Sep 4.

Laboratory of Phytopathology, Plant Sciences Group, and Graduate School of Experimental Plant Sciences, Wageningen University, Binnenhaven 5, NL-6709 PD, Wageningen, The Netherlands.

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http://dx.doi.org/10.1007/s00239-005-0211-3DOI Listing
October 2006

Amplification generates modular diversity at an avirulence locus in the pathogen Phytophthora.

Genome Res 2006 Jul;16(7):827-40

Laboratory of Phytopathology, Plant Sciences Group, Wageningen University, NL-5-6709 PD Wageningen and Graduate School Experimental Plant Sciences, The Netherlands.

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http://www.genome.org/cgi/doi/10.1101/gr.5193806
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http://dx.doi.org/10.1101/gr.5193806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1484450PMC
July 2006

Ancient origin of elicitin gene clusters in Phytophthora genomes.

Mol Biol Evol 2006 Feb 19;23(2):338-51. Epub 2005 Oct 19.

Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands.

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http://mbe.oxfordjournals.org/content/early/2005/10/19/molbe
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http://mbe.oxfordjournals.org/cgi/doi/10.1093/molbev/msj039
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http://dx.doi.org/10.1093/molbev/msj039DOI Listing
February 2006

A cDNA-AFLP based strategy to identify transcripts associated with avirulence in Phytophthora infestans.

Fungal Genet Biol 2006 Feb 7;43(2):111-23. Epub 2006 Feb 7.

Plant Sciences Group, Laboratory of Phytopathology, Wageningen University, Binnenhaven 5, NL-6709 PD Wageningen, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S108718450500169
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http://dx.doi.org/10.1016/j.fgb.2005.11.001DOI Listing
February 2006

Elicitin genes in Phytophthora infestans are clustered and interspersed with various transposon-like elements.

Mol Genet Genomics 2005 Mar 9;273(1):20-32. Epub 2005 Feb 9.

Plant Sciences Group, Laboratory of Phytopathology, Graduate School of Experimental Plant Sciences, Wageningen University, Binnenhaven 5, 6709 PD, Wageningen, The Netherlands.

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http://dx.doi.org/10.1007/s00438-005-1114-0DOI Listing
March 2005

Downstream targets of the Phytophthora infestans Galpha subunit PiGPA1 revealed by cDNA-AFLP.

Mol Plant Pathol 2004 Sep;5(5):483-94

Laboratory of Phytopathology, Wageningen University, Binnenhaven 5, NL-6709 PD Wageningen and Graduate School Experimental Plant Sciences, The Netherlands.

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http://dx.doi.org/10.1111/j.1364-3703.2004.00247.xDOI Listing
September 2004