Publications by authors named "Raymond W Lam"

99Publications

The Quality of Life in Bipolar Disorder (QoL.BD) questionnaire a decade on - A systematic review of the measurement of condition-specific aspects of quality of life in bipolar-disorder.

J Affect Disord 2020 Sep 7;278:33-45. Epub 2020 Sep 7.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.09.017DOI Listing
September 2020

Are There Therapeutic Benefits of Cannabinoid Products in Adult Mental Illness?

Can J Psychiatry 2020 Sep 11:706743720945525. Epub 2020 Sep 11.

Department of Psychiatry, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1177/0706743720945525DOI Listing
September 2020

Predictors of cognitive impairment in treatment-resistant depression.

J Affect Disord 2020 Sep 27;274:593-601. Epub 2020 May 27.

Non-Invasive Neurostimulation Therapies (NINET) Laboratory, Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.05.101DOI Listing
September 2020

Our Digital Moment: Innovations and Opportunities in Digital Mental Health Care.

Can J Psychiatry 2020 Jun 30:706743720937833. Epub 2020 Jun 30.

Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1177/0706743720937833DOI Listing
June 2020

Serum epidermal growth factor, clinical illness course, and limbic brain volumes in early-stage bipolar disorder.

J Affect Disord 2020 Jun 27;270:30-35. Epub 2020 Mar 27.

Mood Disorders Centre, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2020.03.055DOI Listing
June 2020

An investigation of cortical thickness and antidepressant response in major depressive disorder: A CAN-BIND study report.

Neuroimage Clin 2020 13;25:102178. Epub 2020 Jan 13.

Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Mood Disorders Program and Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2020.102178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011077PMC
January 2020

Lithium vs valproate in the maintenance treatment of bipolar I disorder: A post- hoc analysis of a randomized double-blind placebo-controlled trial.

Aust N Z J Psychiatry 2020 03 17;54(3):298-307. Epub 2019 Dec 17.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1177/0004867419894067DOI Listing
March 2020

Cannabidiol as a Treatment for Mood Disorders: A Systematic Review.

Can J Psychiatry 2020 04 13;65(4):213-227. Epub 2019 Dec 13.

Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1177/0706743719895195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385425PMC
April 2020

Light Therapy for Patients With Bipolar Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Can J Psychiatry 2020 May 12;65(5):290-300. Epub 2019 Dec 12.

Department of Psychiatry and Behavioral Sciences, Feinberg Faculty of Medicine, Northwestern University, Chicago, CA, USA.

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http://dx.doi.org/10.1177/0706743719892471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265610PMC
May 2020

Escitalopram ameliorates differences in neural activity between healthy comparison and major depressive disorder groups on an fMRI Emotional conflict task: A CAN-BIND-1 study.

J Affect Disord 2020 Mar 13;264:414-424. Epub 2019 Nov 13.

Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada; Department of Psychology Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.11.068DOI Listing
March 2020

White Matter Indices of Medication Response in Major Depression: A Diffusion Tensor Imaging Study.

Biol Psychiatry Cogn Neurosci Neuroimaging 2019 10 12;4(10):913-924. Epub 2019 Jun 12.

Department of Psychology, Neuroscience & Behavior, McMaster University, Hamilton, Ontario, Canada; Imaging Research Center, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bpsc.2019.05.016DOI Listing
October 2019

Reduced accuracy accompanied by reduced neural activity during the performance of an emotional conflict task by unmedicated patients with major depression: A CAN-BIND fMRI study.

J Affect Disord 2019 10 6;257:765-773. Epub 2019 Jul 6.

Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada; Department of Psychology Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.07.037DOI Listing
October 2019

Reduced accuracy accompanied by reduced neural activity during the performance of an emotional conflict task by unmedicated patients with major depression: A CAN-BIND fMRI study.

J Affect Disord 2019 10 6;257:765-773. Epub 2019 Jul 6.

Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada; Department of Psychology Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.07.037DOI Listing
October 2019

Functional disconnectivity of the hippocampal network and neural correlates of memory impairment in treatment-resistant depression.

J Affect Disord 2019 06 29;253:248-256. Epub 2019 Apr 29.

Non-Invasive Neurostimulation Therapies (NINET) Laboratory, Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.04.096DOI Listing
June 2019

Locating the Site of Neuropathic Pain Using MMP-12-Targeted Magnetic Nanoparticles.

Pain Res Manag 2019;2019:9394715. Epub 2019 Mar 6.

Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228.

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http://dx.doi.org/10.1155/2019/9394715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431387PMC
May 2019

The Canadian Biomarker Integration Network in Depression (CAN-BIND): magnetic resonance imaging protocols

J Psychiatry Neurosci 2019 07;44(4):223-236

From the Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, Alta., Canada (MacQueen, Hassel, Addington, Sharma); the Rotman Research Institute, Baycrest, and Department of Medical Biophysics, University of Toronto, Toronto, Ont., Canada (Arnott, Zamyadi, Strother); the Department of Psychology, Queen’s University, Kingston, Ont., Canada (Bowie, Harkness, Milev); the Department of Radiology, University of Calgary, Calgary, Alta., Canada (Bray, Lebel); the Alberta Children’s Hospital Research Institute, Calgary, Alta., Canada (Bray, Lebel); the Child and Adolescent Imaging Research (CAIR) Program, Calgary, Alta., Canada (Bray, Lebel); the Department of Psychology, Neuroscience and Behaviour, McMaster University, and St. Joseph’s Healthcare Hamilton, Hamilton, Ont., Canada (Hall); the Krembil Research Institute and Centre for Mental Health, University Health Network, Toronto, Ont., Canada (Downar); the Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada (Downar); the Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada (Downar, Müller, Rizvi, Rotzinger, Kennedy); the Department of Psychiatry, Krembil Research Centre, University Health Network, University of Toronto, Toronto, Ont., Canada (Foster, Rotzinger, Kennedy); the Department of Psychiatry and Behavioural Neurosciences, McMaster University, and St. Joseph’s Healthcare Hamilton, Hamilton, Ont., Canada (Foster, Frey); the Centre for Youth Bipolar Disorder, Sunnybrook Health Sciences Centre, Toronto, Ont., Canada (Goldstein); the Departments of Psychiatry and Pharmacology, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada (Goldstein); the Department of Computer Science, University of Alberta, Edmonton, Alta., Canada (Harris); the University of British Columbia and Vancouver Coastal Health Authority, Vancouver, B.C., Canada (Lam, Vila-Rodriguez); the Department of Psychiatry, Queen’s University and Providence Care Hospital, Kingston, Ont., Canada (Milev, Soares); the Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ont., Canada (Müller); the Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA (Parikh); the Arthur Sommer Rotenberg Suicide and Depression Studies Program, Li Ka Shing Knowledge Institute and St. Michael’s Hospital, Toronto, Ont., Canada (Rizvi); the Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada (Rizvi); the Department of Psychiatry, St. Michael’s Hospital, University of Toronto, Toronto, Ont., Canada (Rotzinger, Soares, Yu); McGill University, Montréal, Que., Canada (Turecki); the Douglas Mental Health University Institute, Frank B. Common, Montréal, Que., Canada (Turecki); and the Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ont., Canada (Kennedy).

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http://dx.doi.org/10.1503/jpn.180036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606427PMC
July 2019

Risperidone adjunctive therapy duration in the maintenance treatment of bipolar I disorder: A post hoc analysis.

J Affect Disord 2019 03 5;246:861-866. Epub 2019 Jan 5.

Department of Psychiatry, University of British Columbia; Mood Disorders Centre of Excellence, University of British Columbia, 2255, Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2019.01.003DOI Listing
March 2019

Trajectories of Response to Dorsolateral Prefrontal rTMS in Major Depression: A THREE-D Study.

Am J Psychiatry 2019 05 15;176(5):367-375. Epub 2019 Feb 15.

The Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto (Kaster, Knyahnytska, Daskalakis, Blumberger); the Department of Psychiatry (Kaster, Downar, Giacobbe, Kennedy, Daskalakis, Blumberger), the Institute of Medical Science (Downar, Giacobbe, Kennedy, Daskalakis, Blumberger), and the Dalla Lana School of Public Health (Thorpe), University of Toronto, Toronto; the MRI-Guided rTMS Clinic, Toronto Western Hospital, Toronto (Downar); the Krembil Research Institute, University Health Network, Toronto (Downar, Kennedy); the Department of Psychiatry, University of British Columbia, Vancouver (Vila-Rodriguez, Lam); the Non-Invasive Neurostimulation Therapies Laboratory, University of British Columbia, Vancouver (Vila-Rodriguez); the Shalvata Mental Health Center, Hod-Hasharon, Israel, and the Sackler School of Medicine, Tel Aviv University, Tel Aviv (Feffer); the Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo (Noda); the Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto (Giacobbe); and the Li Ka Shing Knowledge Institute, Saint Michael's Hospital, Toronto (Kennedy).

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2018.18
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http://dx.doi.org/10.1176/appi.ajp.2018.18091096DOI Listing
May 2019

Structural network integrity of the central executive network is associated with the therapeutic effect of rTMS in treatment resistant depression.

Prog Neuropsychopharmacol Biol Psychiatry 2019 06 25;92:217-225. Epub 2019 Jan 25.

Non-Invasive Neurostimulation Therapies (NINET) Laboratory, Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2019.01.012DOI Listing
June 2019

Relationship between work functioning and self-reported cognitive complaints in patients with major depressive disorder treated with desvenlafaxine.

Psychiatry Res 2019 02 10;272:144-148. Epub 2018 Dec 10.

Department of Psychiatry, University of British Columbia, Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183132
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http://dx.doi.org/10.1016/j.psychres.2018.12.062DOI Listing
February 2019

Inclusion of mental health in global economic development.

BJPsych Int 2018 Nov;15(4):74-76

Department of Psychiatry, University of British Columbia, Vancouver, Canada.

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https://www.cambridge.org/core/product/identifier/S205647401
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http://dx.doi.org/10.1192/bji.2017.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277955PMC
November 2018

Discrepancy between objective and subjective cognition in major depressive disorder.

Eur Neuropsychopharmacol 2019 01 28;29(1):46-56. Epub 2018 Nov 28.

Mental Health Department, Neuroscience and Mental Health Research Area, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, CIBERSAM, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2018.11.1104DOI Listing
January 2019

Weight gain as a predictor of frontal and temporal lobe volume loss in bipolar disorder: A prospective MRI study.

Bipolar Disord 2019 02 1;21(1):50-60. Epub 2018 Dec 1.

Mood Disorders Centre, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/bdi.12722DOI Listing
February 2019

Comparison of 21 Antidepressants.

Authors:
Raymond W Lam

Focus (Am Psychiatr Publ) 2018 Oct 18;16(4):4s. Epub 2018 Oct 18.

Dr. Lam is with the Department of Psychiatry, University of British Columbia, and the Mood Disorders Centre, Djavad Mowafaghian Centre for Brain Health, both in Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1176/appi.focus.164S04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493249PMC
October 2018

Early change in reward and punishment sensitivity as a predictor of response to antidepressant treatment for major depressive disorder: a CAN-BIND-1 report.

Psychol Med 2019 07 17;49(10):1629-1638. Epub 2018 Sep 17.

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health,Toronto, ON,Canada.

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http://dx.doi.org/10.1017/S0033291718002441DOI Listing
July 2019

Evidence for the Efficacy of Bright Light Therapy for Bipolar Depression.

Am J Psychiatry 2018 09;175(9):905-906

From the Psychiatry and Clinical Psychobiology Unit, Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy; Psychiatric Medicine Associates, the Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle; the Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Dresden, Germany; the Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine; the Department of Psychiatry, School of Medicine, Trakya University, Edirne, Turkey; the Department of Psychiatry and Psychology, Faculty of Medicine and Surgery, Catholic University of the Sacred Heart, Rome; the Department of Psychiatry, School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; the Section for Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, and the Division of Mental Health Care, Valen Hospital, Fonna Local Health Authority, Norway; the Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna; the Department of Psychiatry, Shiga University of Medical Science, Otsu, Japan; the Department of Psychiatry, University of British Columbia, Vancouver, Canada; Psychiatric Center Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen; University Center for Psychiatry, University Medical Center, Groningen, the Netherlands; the Departments of Psychophysiology and of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo; Psychiatrist Team Alkmaar West, Alkmaar, the Netherlands; the Department of Psychiatry, Nihon University School of Medicine, Tokyo; the Department of Affective Disorders, Institute of Psychiatry and Neurology, Warsaw; Maudsley Hospital and the Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London; the Department of Psychiatry, Marmara University Hospital, Istanbul, Turkey; and the Institute of Mental Health, Peking University, Beijing.

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http://dx.doi.org/10.1176/appi.ajp.2018.18020231DOI Listing
September 2018

Appetitive Symptoms Differentially Predict Treatment Response to Fluoxetine, Light, and Placebo in Nonseasonal Major Depression.

J Clin Psychiatry 2018 07 24;79(4). Epub 2018 Jul 24.

Department of Psychiatry, University of British Columbia; Mood Disorders Centre, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.4088/JCP.17m11856DOI Listing
July 2018

The association of duration and severity of disease with executive function: Differences between drug-naïve patients with bipolar and unipolar depression.

J Affect Disord 2018 10 29;238:412-417. Epub 2018 May 29.

Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine Shanghai 200030, PR China.; CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai 200030, PR China.; Shanghai Key Laboratory of Psychotic disorders, Shanghai 200030, PR China.. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2018.05.051DOI Listing
October 2018

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial.

Lancet 2018 04 26;391(10131):1683-1692. Epub 2018 Apr 26.

Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Centre for Mental Health, University Health Network, Toronto, ON, Canada; MRI-Guided rTMS Clinic, University Health Network, Toronto, ON, Canada; Krembil Research Institute, University Health Network, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183029
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http://dx.doi.org/10.1016/S0140-6736(18)30295-2DOI Listing
April 2018

Use of Placebo in Clinical Trials of Psychotropic Medication.

Can J Psychiatry 2018 05;63(5):338-341

5 Professor and BC Leadership Chair in Depression Research, Department of Psychiatry, University of British Columbia; Director, Mood Disorders Centre, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia.

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http://dx.doi.org/10.1177/0706743717752917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912304PMC
May 2018

Abnormal Functional Connectivity of Frontopolar Subregions in Treatment-Nonresponsive Major Depressive Disorder.

Biol Psychiatry Cogn Neurosci Neuroimaging 2018 04 27;3(4):337-347. Epub 2017 Dec 27.

Krembil Research Institute, University Health Network, Toronto, Canada; MRI-Guided rTMS Clinic, University Health Network, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bpsc.2017.12.003DOI Listing
April 2018

Cognitive Impairment in Major Depressive Disorder: A Case Discussion Illustrating Impact, Assessment, and Management.

J Clin Psychiatry 2018 Jan/Feb;79(1)

University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.4088/JCP.TK16043PD4CDOI Listing
June 2019

Implications of Cannabis Legalization on Youth and Young Adults.

Can J Psychiatry 2018 01;63(1):65-71

6 Professor, Department of Psychiatry and Adjunct Professor, Department of Medical Genetics, University of Alberta.

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http://dx.doi.org/10.1177/0706743718759031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788125PMC
January 2018

Impact of Cognitive Impairment on Functioning in Patients With Depression.

Authors:
Raymond W Lam

J Clin Psychiatry 2017 Nov/Dec;78(9):e1430

University of British Columbia and Mood Disorders Centre, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.4088/JCP.tk16043tx1cDOI Listing
April 2019

Cognitive Impairment in Patients With Depression: Awareness, Assessment, and Management.

J Clin Psychiatry 2017 Nov/Dec;78(9):1383-1394

Mood Disorders Psychopharmacology Unit, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.4088/JCP.tk16043ah5cDOI Listing
April 2019

Monitoring for antidepressant-associated adverse events in the treatment of patients with major depressive disorder: An international consensus statement.

World J Biol Psychiatry 2018 08 6;19(5):330-348. Epub 2017 Oct 6.

a School of Medicine, Barwon Health , Deakin University, IMPACT SRC (Innovation in Mental and Physical Health and Clinical Treatment - Strategic Research Centre) , Geelong , Australia.

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http://dx.doi.org/10.1080/15622975.2017.1379609DOI Listing
August 2018

The impact of fatigue and energy on work functioning and impairment in patients with major depressive disorder treated with desvenlafaxine.

Int Clin Psychopharmacol 2017 11;32(6):343-349

aDepartment of Psychiatry, University of British Columbia bMood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada cDepartment of Physical Medicine and Rehabilitation, Harvard Medical School, and Home Base, a Red Sox Foundation and Massachusetts General Hospital Program, Boston, Massachusetts, USA.

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http://Insights.ovid.com/crossref?an=00004850-201711000-0000
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http://dx.doi.org/10.1097/YIC.0000000000000192DOI Listing
November 2017

A sparse representation-based method for parcellation of the resting brain and its application to treatment-resistant major depressive disorder.

J Neurosci Methods 2017 Oct 22;290:57-68. Epub 2017 Jul 22.

Non-Invasive Neurostimulation Therapies (NINET) Laboratory, Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01650270173026
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http://dx.doi.org/10.1016/j.jneumeth.2017.07.017DOI Listing
October 2017

Subcortical structural volumes in recently remitted first episode mania.

J Affect Disord 2017 11 24;222:23-27. Epub 2017 Jun 24.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.jad.2017.06.051DOI Listing
November 2017

The Efficacy of Psychostimulants in Major Depressive Episodes: A Systematic Review and Meta-Analysis.

J Clin Psychopharmacol 2017 Aug;37(4):412-418

From the *Mood Disorder Psychopharmacology Unit, University Health Network; †Brain and Cognition Discovery Foundation, ‡Department of Psychiatry, §Department of Pharmacology, and ∥Institute of Medical Science, University of Toronto, Toronto, ON, Canada; ¶Department of Psychiatry, University of Saskatchewan, Saskatoon, SK, Canada; #Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; and **Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, Columbia, SC.

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http://dx.doi.org/10.1097/JCP.0000000000000723DOI Listing
August 2017

Adjunctive ketamine in electroconvulsive therapy: updated systematic review and meta-analysis.

Br J Psychiatry 2017 06 6;210(6):403-407. Epub 2017 Apr 6.

Alexander McGirr, MD, MSc, Department of Psychiatry, University of British Columbia, Vancouver; Marcelo T. Berlim, MD, MSc, Neuromodulation Research Clinic, Depressive Disorders Program, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada; David J. Bond, MD, PhD, Department of Psychiatry, University of Minnesota, Minneapolis, USA; Peter Y. Chan, MD, Department of Psychiatry, University of British Columbia, and Neurostimulation Service, Vancouver General Hospital, Vancouver; Lakshmi N. Yatham, MBBS, Raymond W. Lam, MD, Department of Psychiatry and Mood Disorders Centre of Excellence, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1192/bjp.bp.116.195826DOI Listing
June 2017

Lurasidone versus treatment as usual for cognitive impairment in euthymic patients with bipolar I disorder: a randomised, open-label, pilot study.

Lancet Psychiatry 2017 03 7;4(3):208-217. Epub 2017 Feb 7.

Mood Disorders Centre of Excellence, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/S2215-0366(17)30046-9DOI Listing
March 2017

Safety and efficacy of adjunctive second-generation antidepressant therapy with a mood stabiliser or an atypical antipsychotic in acute bipolar depression: a systematic review and meta-analysis of randomised placebo-controlled trials.

Lancet Psychiatry 2016 12 26;3(12):1138-1146. Epub 2016 Oct 26.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; Mood Disorders Centre of Excellence, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22150366163026
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http://dx.doi.org/10.1016/S2215-0366(16)30264-4DOI Listing
December 2016

The Depression Inventory Development Workgroup: A Collaborative, Empirically Driven Initiative to Develop a New Assessment Tool for Major Depressive Disorder.

Innov Clin Neurosci 2016 Sep-Oct;13(9-10):20-31. Epub 2016 Oct 1.

Dr. Vaccarino is with Indoc Research, Toronto, Ontario, Canada; Dr. Evans is with Indoc Research, Toronto, Ontario, Canada, and Department of Pathology and Molecular Medicine, Queen's University, Kingston, Ontario, Canada; Dr. Kalali is with Quintiles Inc, San Diego, California, USA, and Department of Psychiatry, University of California, San Diego, California, USA; Drs. Kennedy and Placenza are with University Health Network, Toronto, Ontario, Canada; Dr. Engelhardt is with Cronos Clinical Consulting Services, Lambertville, New Jersey, USA; Dr. Frey is with Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada, and Mood Disorders Program and Women's Health Concerns Clinic, St. Joseph's Healthcare, Hamilton, Ontario, Canada; Dr. Greist is with Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA; Dr. Kobak is with Center for Telepsychology, Madison, Wisconsin, USA; Dr. Lam is with Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada; Dr. MacQueen is with Mathison Centre for Mental Health Research and Education, Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada; Dr. Milev is with Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Dr. Ravindran is with Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada, and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Dr. Sheehan is with Department of Psychiatry and Behavioral Health, University of South Florida College of Medicine, Tampa, Florida, USA; Dr. Sills was with OCBN, Toronto, Ontario, Canada; Dr. Williams is with Columbia University, New York, New York, USA, and Medavante Inc., Trenton, New Jersey, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141593PMC
October 2016

The effect of remission status on work functioning in employed patients treated for major depressive disorder.

Ann Clin Psychiatry 2017 02;29(1):11-16

Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

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February 2017

S-adenosyl methionine (SAMe) for depression in adults.

Cochrane Database Syst Rev 2016 Oct 10;10:CD011286. Epub 2016 Oct 10.

Centre for Affective Disorders, King's College London, Institute of Psychiatry, De Crespigny Park, London, UK, SE5 8AF.

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http://dx.doi.org/10.1002/14651858.CD011286.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457972PMC
October 2016

Trajectories of body mass index change in first episode of mania: 3-year data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).

J Affect Disord 2017 Jan 11;208:291-297. Epub 2016 Oct 11.

Mood Disorders Centre of Excellence, University of British Columbia, 2255, Wesbrook Mall, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2016.08.048DOI Listing
January 2017

A Longitudinal Study of the Relationships Between Mood Symptoms, Body Mass Index, and Serum Adipokines in Bipolar Disorder.

J Clin Psychiatry 2017 Apr;78(4):441-448

Department of Psychiatry, University of British Columbia, Room 2C7-2255 Wesbrook Mall, Vancouver, BC, Canada V6T 2A1.

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http://dx.doi.org/10.4088/JCP.15m10189DOI Listing
April 2017

Structural brain changes in first episode mania with and without psychosis: Data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).

World J Biol Psychiatry 2018 8;19(sup2):S30-S40. Epub 2016 Dec 8.

a Department of Psychiatry , University of British Columbia , Vancouver , BC , Canada.

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http://dx.doi.org/10.1080/15622975.2016.1249950DOI Listing
May 2019

Ketamine: stimulating antidepressant treatment?

BJPsych Open 2016 May 11;2(3):e5-e9. Epub 2016 May 11.

, MD, Professor and Chairman of the Department of Psychiatry & Behavioural Sciences at the University of New Mexico, Albuquerque, NM, USA.

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http://dx.doi.org/10.1192/bjpo.bp.116.002923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995167PMC
May 2016

The effects of desvenlafaxine on neurocognitive and work functioning in employed outpatients with major depressive disorder.

J Affect Disord 2016 Oct 31;203:55-61. Epub 2016 May 31.

Department of Psychiatry, University of British Columbia, Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Canada.

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http://dx.doi.org/10.1016/j.jad.2016.05.074DOI Listing
October 2016

Selection of cognitive tests for trials of therapeutic agents.

Lancet Psychiatry 2016 06;3(6):499

Mood Disorders Psychopharmacology Unit, Toronto Western Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S2215-0366(16)30067-0DOI Listing
June 2016

The Effects of Newer Antidepressants on Occupational Impairment in Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

CNS Drugs 2016 May;30(5):405-17

Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada.

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http://dx.doi.org/10.1007/s40263-016-0334-7DOI Listing
May 2016

Cognitive Dysfunction in Major Depressive Disorder: Assessment, Impact, and Management.

Focus (Am Psychiatr Publ) 2016 Apr 7;14(2):194-206. Epub 2016 Apr 7.

The authors are with the Department of Psychiatry, University of British Columbia, and the Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada. Send correspondence to Dr. Lam (e-mail:

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http://dx.doi.org/10.1176/appi.focus.20150043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519654PMC
April 2016

From the Guest Editors.

Focus (Am Psychiatr Publ) 2016 Apr 7;14(2):155. Epub 2016 Apr 7.

Dr. Hadjipavlou and Dr. Lam are with the Department of Psychiatry, University of British Columbia, Vancouver, and the Mood Disorders Centre of Excellence, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada (e-mail:

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http://dx.doi.org/10.1176/appi.focus.20160002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519656PMC
April 2016

Heparin-Based Polyelectrolyte Complex Enhances the Therapeutic Efficacy of Bone Morphogenetic Protein-2 for Posterolateral Fusion in a Large Animal Model.

Spine (Phila Pa 1976) 2016 Aug;41(15):1199-207

*Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore †Institute of Medical Biology ‡Singapore Bioimaging Consortium §Institute of Materials Research and Engineering, A*STAR ¶Department of Bioengineering, Faculty of Engineering, National University of Singapore.

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http://dx.doi.org/10.1097/BRS.0000000000001543DOI Listing
August 2016

Sinus Tachycardia Induced by Methocarbamol and Repetitive Transcranial Magnetic Stimulation (rTMS).

Brain Stimul 2016 Jan-Feb;9(1):156-8. Epub 2015 Nov 24.

Non-Invasive Neurostimulation Therapies Lab at UBC, Department of Psychiatry, University of British Columbia, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2015.10.012DOI Listing
May 2016