Raymond C Trievel

Raymond C Trievel

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Raymond C Trievel

Raymond C Trievel

Publications by authors named "Raymond C Trievel"

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An H3K9 methylation dependent protein interaction regulates the non-enzymatic function of a putative histone demethylase.

Elife 2020 Mar 20;9. Epub 2020 Mar 20.

Department of Biological Chemistry, University of Michigan, Ann Arbor, United States.

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http://dx.doi.org/10.7554/eLife.53155DOI Listing
March 2020

Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.

Biochemistry 2019 04 8;58(16):2152-2159. Epub 2019 Apr 8.

Department of Biological Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acs.biochem.8b01141DOI Listing
April 2019

Reply to 'Misreading chaperone-substrate complexes from random noise'.

Nat Struct Mol Biol 2018 11;25(11):990-991

Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41594-018-0145-2DOI Listing
November 2018

Crystallographic and Computational Characterization of Methyl Tetrel Bonding in S-Adenosylmethionine-Dependent Methyltransferases.

Molecules 2018 Nov 13;23(11). Epub 2018 Nov 13.

Department of Chemistry and Biochemistry, Utah State University, Logan, UT 84322, USA.

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http://dx.doi.org/10.3390/molecules23112965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278250PMC
November 2018

Structure, mechanism, and regulation of polycomb-repressive complex 2.

J Biol Chem 2018 09 14;293(36):13805-13814. Epub 2017 Sep 14.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109

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http://dx.doi.org/10.1074/jbc.R117.800367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130931PMC
September 2018

Water-Mediated Carbon-Oxygen Hydrogen Bonding Facilitates S-Adenosylmethionine Recognition in the Reactivation Domain of Cobalamin-Dependent Methionine Synthase.

Biochemistry 2018 07 21;57(26):3733-3740. Epub 2018 May 21.

Department of Biological Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acs.biochem.8b00375DOI Listing
July 2018

Measuring the Kinetics of Molecular Association by Isothermal Titration Calorimetry.

Methods Enzymol 2016 9;567:181-213. Epub 2015 Oct 9.

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2015.08.012DOI Listing
October 2016

Visualizing chaperone-assisted protein folding.

Nat Struct Mol Biol 2016 07 30;23(7):691-7. Epub 2016 May 30.

Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/nsmb.3237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937829PMC
July 2016

Sulfur-Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9.

ACS Chem Biol 2016 Mar 12;11(3):748-54. Epub 2016 Jan 12.

Department of Chemistry and Biochemistry, Utah State University , Logan, Utah 84322, United States.

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http://dx.doi.org/10.1021/acschembio.5b00852DOI Listing
March 2016

7 Non-histone protein lysine methyltransferases: Structure and catalytic roles.

Enzymes 2006 4;24:179-228. Epub 2007 Jun 4.

Department of Horticulture University of Kentucky 407 Plant Science Building Lexington, KY 40546, USA.

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http://dx.doi.org/10.1016/S1874-6047(06)80009-0DOI Listing
January 2016

Frequent side chain methyl carbon-oxygen hydrogen bonding in proteins revealed by computational and stereochemical analysis of neutron structures.

Proteins 2015 Mar 21;83(3):403-410. Epub 2015 Jan 21.

Department of Biological Chemistry, Howard Hughes Medical Institute, University of Michigan, Ann Arbor MI 48109 USA.

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http://dx.doi.org/10.1002/prot.24724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747036PMC
March 2015

Molecular basis for substrate recognition by lysine methyltransferases and demethylases.

Biochim Biophys Acta 2014 Dec 17;1839(12):1404-15. Epub 2014 Jun 17.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2014.06.008DOI Listing
December 2014

Crystal structure of Saccharomyces cerevisiae Aro8, a putative α-aminoadipate aminotransferase.

Protein Sci 2013 Oct 28;22(10):1417-24. Epub 2013 Aug 28.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, 48109.

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http://dx.doi.org/10.1002/pro.2315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795499PMC
October 2013

Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.

J Am Chem Soc 2013 Oct 7;135(41):15536-48. Epub 2013 Oct 7.

Howard Hughes Medical Institute , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/ja407140kDOI Listing
October 2013

An overview of chromatin modifications.

Biopolymers 2013 Feb;99(2):95-7

Department of Biological Chemistry, University of Michigan, Ann Arbor MI, 48109.

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http://dx.doi.org/10.1002/bip.22158DOI Listing
February 2013

Structural and functional analysis of JMJD2D reveals molecular basis for site-specific demethylation among JMJD2 demethylases.

Structure 2013 Jan 6;21(1):98-108. Epub 2012 Dec 6.

Department of Biological Chemistry, 1150 West Medical Center Drive, 5301 Medical Science Research Building III, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2012.10.018DOI Listing
January 2013

Carbon-oxygen hydrogen bonding in biological structure and function.

J Biol Chem 2012 Dec 9;287(50):41576-82. Epub 2012 Oct 9.

Department of Biophysics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.R112.418574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516709PMC
December 2012

Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function.

Mol Cell Biol 2012 Oct 30;32(19):4044-52. Epub 2012 Jul 30.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1128/MCB.00513-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457536PMC
October 2012

Crystal structure of homoisocitrate dehydrogenase from Schizosaccharomyces pombe.

Proteins 2012 Feb 22;80(2):661-6. Epub 2011 Nov 22.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109.

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http://dx.doi.org/10.1002/prot.23231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332711PMC
February 2012

Purification and assay protocols for obtaining highly active Jumonji C demethylases.

Anal Biochem 2012 Jan 26;420(1):48-53. Epub 2011 Aug 26.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.ab.2011.08.034DOI Listing
January 2012

Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human.

Proc Natl Acad Sci U S A 2011 Dec 7;108(51):20526-31. Epub 2011 Dec 7.

Stowers Institute for Medical Research, Kansas City, MO 64110, USA.

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http://dx.doi.org/10.1073/pnas.1109360108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251153PMC
December 2011

Substrate and product specificities of SET domain methyltransferases.

Epigenetics 2011 Sep 1;6(9):1059-67. Epub 2011 Sep 1.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.4161/epi.6.9.16069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225744PMC
September 2011

Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9.

J Biol Chem 2011 May 18;286(21):18658-63. Epub 2011 Mar 18.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.M111.232876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099682PMC
May 2011

Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase.

Anal Biochem 2011 Mar 10;410(1):133-40. Epub 2010 Nov 10.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.ab.2010.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115995PMC
March 2011

Structure and function of histone H3 lysine 9 methyltransferases and demethylases.

Chembiochem 2011 Jan 5;12(2):254-63. Epub 2011 Jan 5.

University of Michigan Medical School, Department of Biological Chemistry, Ann Arbor, MI 48109, USA.

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http://doi.wiley.com/10.1002/cbic.201000545
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http://dx.doi.org/10.1002/cbic.201000545DOI Listing
January 2011

Calmodulin methyltransferase is an evolutionarily conserved enzyme that trimethylates Lys-115 in calmodulin.

Nat Commun 2010 Jul 27;1:43. Epub 2010 Jul 27.

Department of Horticulture, Plant Physiology/Biochemistry/Molecular Biology Program, University of Kentucky, Lexington, Kentucky 40546, USA.

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http://dx.doi.org/10.1038/ncomms1044DOI Listing
July 2010

Structural basis for L-lysine feedback inhibition of homocitrate synthase.

J Biol Chem 2010 Apr 19;285(14):10446-53. Epub 2010 Jan 19.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.M109.094383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856251PMC
April 2010

Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis.

J Biol Chem 2009 Dec;284(51):35769-80

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.M109.046821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791007PMC
December 2009

WDR5, a complexed protein.

Nat Struct Mol Biol 2009 Jul;16(7):678-80

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/nsmb0709-678DOI Listing
July 2009

Rubisco in complex with Rubisco large subunit methyltransferase.

Proc Natl Acad Sci U S A 2009 Mar 10;106(9):3160-5. Epub 2009 Feb 10.

Department of Cell Biology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0810563106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638739PMC
March 2009

Histone modifying enzymes: structures, mechanisms, and specificities.

Biochim Biophys Acta 2009 Jan 3;1789(1):58-68. Epub 2008 Aug 3.

Program in Gene Expression and Regulation, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2008.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059211PMC
January 2009

Structural origins for the product specificity of SET domain protein methyltransferases.

Proc Natl Acad Sci U S A 2008 Dec 16;105(52):20659-64. Epub 2008 Dec 16.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.0806712105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634886PMC
December 2008

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.

Nat Struct Mol Biol 2007 Aug 24;14(8):689-95. Epub 2007 Jun 24.

Department of Biological Chemistry, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109-0606, USA.

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http://dx.doi.org/10.1038/nsmb1273DOI Listing
August 2007

Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3.

FEBS Lett 2007 Jul 21;581(17):3289-96. Epub 2007 Jun 21.

University of Southern California Keck School of Medicine, Department of Biochemistry and Molecular Biology, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/j.febslet.2007.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045647PMC
July 2007

Kinetic manifestation of processivity during multiple methylations catalyzed by SET domain protein methyltransferases.

Biochemistry 2007 Mar 6;46(12):3905-15. Epub 2007 Mar 6.

Department of Horticulture, Plant Physiology/Biochemistry/Molecular Biology Program, 401D Plant Science Building, University of Kentucky, Lexington, Kentucky 40546-0312, USA.

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http://dx.doi.org/10.1021/bi6023644DOI Listing
March 2007

Histone-modifying enzymes: encrypting an enigmatic epigenetic code.

Curr Opin Struct Biol 2006 Dec 27;16(6):753-60. Epub 2006 Oct 27.

Department of Biological Chemistry, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI 48109-0606, USA.

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http://dx.doi.org/10.1016/j.sbi.2006.10.002DOI Listing
December 2006

Molecular recognition of histone H3 by the WD40 protein WDR5.

Nat Struct Mol Biol 2006 Aug 9;13(8):698-703. Epub 2006 Jul 9.

Department of Biological Chemistry, University of Michigan, 1301 Catherine Road, Ann Arbor, Michigan 48109-0606, USA.

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http://dx.doi.org/10.1038/nsmb1116DOI Listing
August 2006

The SET-domain protein superfamily: protein lysine methyltransferases.

Genome Biol 2005 2;6(8):227. Epub 2005 Aug 2.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1186/gb-2005-6-8-227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1273623PMC
July 2006

Catalytic roles for carbon-oxygen hydrogen bonding in SET domain lysine methyltransferases.

J Biol Chem 2006 Jul 8;281(28):19280-7. Epub 2006 May 8.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1074/jbc.M602257200DOI Listing
July 2006

Structural basis for the methylation site specificity of SET7/9.

Nat Struct Mol Biol 2006 Feb 15;13(2):140-6. Epub 2006 Jan 15.

Department of Biological Chemistry, University of Michigan, 1301 Catherine Road, Ann Arbor, Michigan 48109-0606, USA.

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http://dx.doi.org/10.1038/nsmb1045DOI Listing
February 2006

A coupled fluorescent assay for histone methyltransferases.

Anal Biochem 2005 Jul;342(1):86-92

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109-0606, USA.

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http://dx.doi.org/10.1016/j.ab.2005.04.007DOI Listing
July 2005

Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase.

Genes Dev 2005 Jun 2;19(12):1455-65. Epub 2005 Jun 2.

Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1101/gad.1318405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151662PMC
June 2005

Structure and function of histone methyltransferases.

Crit Rev Eukaryot Gene Expr 2004 ;14(3):147-69

University of Michigan Medical School, Department of Biological Chemistry, Ann Arbor, MI 48109-0606, USA.

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http://dx.doi.org/10.1615/critreveukaryotgeneexpr.v14.i3.10DOI Listing
May 2005

Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT.

Nat Struct Biol 2003 Jul;10(7):545-52

Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nsb946DOI Listing
July 2003

Structure and catalytic mechanism of a SET domain protein methyltransferase.

Cell 2002 Oct;111(1):91-103

Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/s0092-8674(02)01000-0DOI Listing
October 2002