Raymond A Dwek

Raymond A Dwek

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Raymond A Dwek

Raymond A Dwek

Publications by authors named "Raymond A Dwek"

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Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model.

PLoS One 2016 23;11(11):e0167018. Epub 2016 Nov 23.

Antiviral Research Unit, Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167018PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120828PMC
June 2017

Iminosugar antivirals: the therapeutic sweet spot.

Biochem Soc Trans 2017 04;45(2):571-582

Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K.

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http://dx.doi.org/10.1042/BST20160182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390498PMC
April 2017

Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids.

Innate Immun 2015 Feb 3;21(2):175-93. Epub 2014 Mar 3.

Department of Integrative Structural and Computational Biology, and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, USA

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http://dx.doi.org/10.1177/1753425914524077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392886PMC
February 2015

Journeys in science: glycobiology and other paths.

Authors:
Raymond A Dwek

Annu Rev Biochem 2014 15;83:1-44. Epub 2014 Jan 15.

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom; email:

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http://dx.doi.org/10.1146/annurev-biochem-041612-095236DOI Listing
January 2015

Emerging principles for the therapeutic exploitation of glycosylation.

Science 2014 Jan;343(6166):1235681

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://dx.doi.org/10.1126/science.1235681DOI Listing
January 2014

Directing stem cell differentiation with antibodies.

Proc Natl Acad Sci U S A 2013 Oct 18;110(44):17608-9. Epub 2013 Oct 18.

Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1317614110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816410PMC
October 2013

Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.

Cell Mol Life Sci 2013 Aug 16;70(15):2799-814. Epub 2013 Mar 16.

Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.

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http://link.springer.com/10.1007/s00018-013-1304-6
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http://dx.doi.org/10.1007/s00018-013-1304-6DOI Listing
August 2013

Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.

PLoS One 2012 26;7(6):e39603. Epub 2012 Jun 26.

Oxford Antiviral Drug Discovery Unit, Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039603PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383672PMC
March 2013

Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase.

Biochem J 2011 Aug;438(1):133-42

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://biochemj.org/lookup/doi/10.1042/BJ20110186
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http://dx.doi.org/10.1042/BJ20110186DOI Listing
August 2011

New approaches for biomarker discovery: the search for liver fibrosis markers in hepatitis C patients.

J Proteome Res 2011 May 30;10(5):2643-50. Epub 2011 Mar 30.

Oxford Antiviral Drug Discovery Unit, Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1021/pr101077cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089987PMC
May 2011

Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells.

Proc Natl Acad Sci U S A 2010 Oct 20;107(40):17176-81. Epub 2010 Sep 20.

Oxford Antiviral Drug Discovery Unit, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1009445107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951407PMC
October 2010

The N-glycosylation of classical swine fever virus E2 glycoprotein extracellular domain expressed in the milk of goat.

Arch Biochem Biophys 2010 Aug 10;500(2):169-80. Epub 2010 May 10.

Department of Carbohydrate Chemistry, Center for Genetic Engineering and Biotechnology, Havana, Cuba.

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https://linkinghub.elsevier.com/retrieve/pii/S00039861100017
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http://dx.doi.org/10.1016/j.abb.2010.05.006DOI Listing
August 2010

Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

Proc Natl Acad Sci U S A 2010 Aug 19;107(31):13800-5. Epub 2010 Jul 19.

Department of Immunology and Microbial Science and International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.1006498107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922250PMC
August 2010

Uptake and trafficking of liposomes to the endoplasmic reticulum.

FASEB J 2010 Jun 22;24(6):1866-78. Epub 2010 Jan 22.

Oxford Antiviral Drug Discovery Unit, Department of Biochemistry, University of Oxford, Oxford, UK.

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http://www.fasebj.org/doi/10.1096/fj.09-145755
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http://dx.doi.org/10.1096/fj.09-145755DOI Listing
June 2010

Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants.

Anal Biochem 2010 May 28;400(2):173-83. Epub 2010 Jan 28.

Department of Carbohydrate Chemistry, Center for Genetic Engineering and Biotechnology, Havana, Cuba.

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http://dx.doi.org/10.1016/j.ab.2010.01.027DOI Listing
May 2010

Fragmentation of negative ions from N-linked carbohydrates, part 4. Fragmentation of complex glycans lacking substitution on the 6-antenna.

J Mass Spectrom 2010 May;45(5):528-35

Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.

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http://dx.doi.org/10.1002/jms.1736DOI Listing
May 2010

Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein.

Virology 2010 Apr 2;399(2):257-69. Epub 2010 Feb 2.

Oxford Glycobiology Institute, Department of Biochemistry, South Parks Road, Oxford OX1 3QU, UK.

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http://dx.doi.org/10.1016/j.virol.2009.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412594PMC
April 2010

Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.

Glycoconj J 2010 Apr 26;27(3):297-308. Epub 2010 Feb 26.

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.

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http://dx.doi.org/10.1007/s10719-010-9278-1DOI Listing
April 2010

Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected].

Proc Natl Acad Sci U S A 2010 Feb 28;107(7):3052-7. Epub 2010 Jan 28.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0915056107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840327PMC
February 2010

Identification of high-mannose and multiantennary complex-type N-linked glycans containing alpha-galactose epitopes from Nurse shark IgM heavy chain.

Glycoconj J 2009 Nov;26(8):1055-64

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://dx.doi.org/10.1007/s10719-008-9226-5DOI Listing
November 2009

A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus.

J Biol Chem 2009 Aug 22;284(32):21684-95. Epub 2009 May 22.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M109.006254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755891PMC
August 2009

The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.

Proc Natl Acad Sci U S A 2009 Aug 9;106(31):12712-6. Epub 2009 Jul 9.

Department of Biochemistry and Oxford Glycobiology Institute, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0905966106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722341PMC
August 2009

Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.

Proteomics 2009 Aug;9(15):3796-801

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, UK.

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http://dx.doi.org/10.1002/pmic.200900096DOI Listing
August 2009

Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation.

Biochem Biophys Res Commun 2009 Jul 8;384(4):436-43. Epub 2009 May 8.

Glycobiology Institute, Biochemistry Department, University of Oxford, South Parks Road, OX1, 3QU, United Kingdom.

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http://dx.doi.org/10.1016/j.bbrc.2009.04.159DOI Listing
July 2009

N-glycosylation pattern of E2 glycoprotein from classical swine fever virus.

J Proteome Res 2009 Feb;8(2):546-55

Department of Carbohydrate Chemistry, Center for Genetic Engineering and Biotechnology, Havana 10600, Cuba.

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http://dx.doi.org/10.1021/pr800725vDOI Listing
February 2009

Development of a single column method for the separation of lipid- and protein-derived oligosaccharides.

J Proteome Res 2009 Feb;8(2):681-7

Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://pubs.acs.org/doi/abs/10.1021/pr800704t
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http://dx.doi.org/10.1021/pr800704tDOI Listing
February 2009

Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.

Dis Markers 2008 ;25(4-5):219-32

Dublin-Oxford Glycobiology Laboratory, NIBRT, Conway Institute, UCD, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827796PMC
http://dx.doi.org/10.1155/2008/601583DOI Listing
February 2009

Proteomic analysis of HepaRG cells: a novel cell line that supports hepatitis B virus infection.

J Proteome Res 2009 Jan;8(1):118-22

Oxford Antiviral Drug Discovery Unit, Oxford, OX1 3QU, UK.

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http://dx.doi.org/10.1021/pr800562jDOI Listing
January 2009

Glycan structures of ocular surface mucins in man, rabbit and dog display species differences.

Glycoconj J 2008 Nov 9;25(8):763-73. Epub 2008 May 9.

Department of Biochemistry, Glycobiology Institute, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.

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http://dx.doi.org/10.1007/s10719-008-9136-6DOI Listing
November 2008

Structural characterization of the 1918 influenza virus H1N1 neuraminidase.

J Virol 2008 Nov 20;82(21):10493-501. Epub 2008 Aug 20.

Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00959-08
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http://dx.doi.org/10.1128/JVI.00959-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573172PMC
November 2008

N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.

AIDS 2008 Oct;22(15):1961-9

Oxford Antiviral Drug Discovery Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK.

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https://insights.ovid.com/crossref?an=00002030-200810010-000
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http://dx.doi.org/10.1097/QAD.0b013e32830efd96DOI Listing
October 2008

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.

AIDS 2008 Oct;22(16):2214-7

Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1097/QAD.0b013e328314b5dfDOI Listing
October 2008

Plant N-glycan profiling of minute amounts of material.

Anal Biochem 2008 Aug 25;379(1):66-72. Epub 2008 Apr 25.

CNRS-FRE 3090, IFRMP 23, Université de Rouen, 76821 Mont Saint Aignan Cédex, France; Medicago Inc., Québec, QC G1V 3V9, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00032697080026
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http://dx.doi.org/10.1016/j.ab.2008.04.034DOI Listing
August 2008

The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum.

Glycobiology 2008 Jun 10;18(6):456-62. Epub 2008 Mar 10.

Tumour Immunology Group, University of Nottingham, Division of Breast Surgery, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK.

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http://dx.doi.org/10.1093/glycob/cwn022DOI Listing
June 2008

Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis.

Mol Genet Metab 2008 Jun 1;94(2):204-11. Epub 2008 Apr 1.

Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S109671920800050
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http://dx.doi.org/10.1016/j.ymgme.2008.02.005DOI Listing
June 2008

Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry.

Anal Biochem 2008 May 31;376(1):44-60. Epub 2008 Jan 31.

Oxford Glycobiology Institute, Department of Biochemistry, South Parks Road, Oxford OX1 3QU, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S000326970800041
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http://dx.doi.org/10.1016/j.ab.2008.01.025DOI Listing
May 2008

GlycoBase and autoGU: tools for HPLC-based glycan analysis.

Bioinformatics 2008 May 14;24(9):1214-6. Epub 2008 Mar 14.

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://bioinformatics.oxfordjournals.org/content/24/9/1214.f
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http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/btn090DOI Listing
May 2008

Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma.

Mol Immunol 2008 Mar 19;45(6):1567-72. Epub 2007 Nov 19.

Genetic Vaccine Group, Cancer Sciences Division, University of Southampton School of Medicine, Southampton, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900700803
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http://dx.doi.org/10.1016/j.molimm.2007.10.009DOI Listing
March 2008

Making autoantibodies safe.

Proc Natl Acad Sci U S A 2008 Mar 14;105(11):4081-2. Epub 2008 Mar 14.

Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0801192105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2393817PMC
March 2008

High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads.

Chem Biol 2008 Mar;15(3):215-23

Interdisciplinary Program for Biochemical Engineering and Biotechnology, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1016/j.chembiol.2008.02.009DOI Listing
March 2008

Increased levels of galactose-deficient anti-Gal immunoglobulin G in the sera of hepatitis C virus-infected individuals with fibrosis and cirrhosis.

J Virol 2008 Feb 28;82(3):1259-70. Epub 2007 Nov 28.

Drexel University College of Medicine and Department of Microbiology and Immunology and Drexel Institute for Biotechnology and Virology, Doylestown, PA 18901, USA.

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http://dx.doi.org/10.1128/JVI.01600-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224448PMC
February 2008

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum alpha-glucosidase inhibition.

Biochem J 2008 Jan;409(2):571-80

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://dx.doi.org/10.1042/BJ20070748DOI Listing
January 2008

Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.

Glycobiology 2007 Dec 20;17(12):1344-56. Epub 2007 Sep 20.

Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/glycob/cwm100DOI Listing
December 2007

Changes of serum glycans during sepsis and acute pancreatitis.

Glycobiology 2007 Dec 15;17(12):1321-32. Epub 2007 Oct 15.

Department of Biochemistry and Molecular Biology, University of Zagreb Faculty of Pharmacy and Biochemistry, 10000, Zagreb, Croatia.

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http://dx.doi.org/10.1093/glycob/cwm106DOI Listing
December 2007

Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis.

J Biol Chem 2007 Nov 11;282(45):32655-64. Epub 2007 Sep 11.

Departments of Biochemistry and Pharmacology, University of Oxford, Mansfield Road, Oxford, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M702387200DOI Listing
November 2007

Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity.

Antiviral Res 2007 Oct 22;76(1):30-7. Epub 2007 May 22.

Institute of Biochemistry, Splaiul Independentei, 296, Sector 6, Bucharest 77700, Romania.

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http://dx.doi.org/10.1016/j.antiviral.2007.04.004DOI Listing
October 2007

Novel serum biomarker candidates for liver fibrosis in hepatitis C patients.

Clin Chem 2007 Oct 16;53(10):1792-9. Epub 2007 Aug 16.

Oxford Antiviral Drug Discovery Unit, Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1373/clinchem.2007.089144DOI Listing
October 2007

Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus.

Hepatology 2007 Aug;46(2):330-8

Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hep.21686DOI Listing
August 2007

Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum.

J Proteome Res 2007 Jul 1;6(7):2802-11. Epub 2007 Jun 1.

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom.

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http://pubs.acs.org/doi/abs/10.1021/pr070021t
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http://dx.doi.org/10.1021/pr070021tDOI Listing
July 2007

The impact of glycosylation on the biological function and structure of human immunoglobulins.

Annu Rev Immunol 2007 ;25:21-50

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom.

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http://dx.doi.org/10.1146/annurev.immunol.25.022106.141702DOI Listing
June 2007

Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation.

FEBS Lett 2007 May 20;581(10):1963-8. Epub 2007 Apr 20.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK.

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http://doi.wiley.com/10.1016/j.febslet.2007.04.020
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http://dx.doi.org/10.1016/j.febslet.2007.04.020DOI Listing
May 2007

Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.

Glycobiology 2007 Apr 17;17(4):388-400. Epub 2007 Jan 17.

Unitat de Bioquímica i Biologia Molecular, Departament de Biologia, Universitat de Girona, Campus de Montilivi, Girona 17071, Spain.

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http://dx.doi.org/10.1093/glycob/cwm002DOI Listing
April 2007

Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.

Proc Natl Acad Sci U S A 2007 Apr 26;104(14):5983-8. Epub 2007 Mar 26.

Cancer Sciences Division, School of Medicine, Southampton General Hospital, University of Southampton, Tremona Road, Southampton SO16 6YD, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0701307104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851603PMC
April 2007

Proteomics in uveal melanoma research: opportunities and challenges in biomarker discovery.

Expert Rev Proteomics 2007 Apr;4(2):273-86

Universidad de Santiago de Compostela, Laboratorio de Endocrinología Molecular, Departamento de Medicina, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.

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http://dx.doi.org/10.1586/14789450.4.2.273DOI Listing
April 2007

Exploiting the defensive sugars of HIV-1 for drug and vaccine design.

Nature 2007 Apr;446(7139):1038-45

Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

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http://www.nature.com/doifinder/10.1038/nature05818
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http://dx.doi.org/10.1038/nature05818DOI Listing
April 2007

Glycoprotein structural genomics: solving the glycosylation problem.

Structure 2007 Mar;15(3):267-73

Nuffield Department of Clinical Medicine and MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1016/j.str.2007.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885966PMC
March 2007

Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.

Mol Biochem Parasitol 2007 Feb 27;151(2):148-61. Epub 2006 Nov 27.

Department of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.molbiopara.2006.10.019DOI Listing
February 2007

Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions.

Methods Mol Biol 2006 ;347:125-43

Department of Biochemistry, Glycobiology Institute, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1385/1-59745-167-3:125DOI Listing
January 2007

Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.

Biochemistry 2006 Dec 6;45(51):15249-58. Epub 2006 Dec 6.

Glycobiology Institute, Department of Biochemistry, University of Oxford, UK.

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http://dx.doi.org/10.1021/bi061254lDOI Listing
December 2006

Oligosaccharides modulate the apoptotic activity of glycodelin.

Glycobiology 2006 Nov 19;16(11):1052-63. Epub 2006 Jul 19.

Department of Biochemistry, Indian Institute of Science, Balgalore 560012, India.

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http://dx.doi.org/10.1093/glycob/cwl024DOI Listing
November 2006

Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.

Biochim Biophys Acta 2006 Nov 16;1764(11):1757-66. Epub 2006 Sep 16.

MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, England, UK.

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November 2006

Structural aspects of glycomes with a focus on N-glycosylation and glycoprotein folding.

Curr Opin Struct Biol 2006 Oct 30;16(5):600-7. Epub 2006 Aug 30.

Institute of Biochemistry, Splaiul Independenţei 296, 060031 Bucharest 17, Romania.

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October 2006

Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals.

Curr Opin Struct Biol 2006 Oct 11;16(5):576-83. Epub 2006 Sep 11.

CNRS-UMR 6037, GDR G3, IFRMP 23, Université de Rouen, 76821 Mont Saint Aignan Cédex, France.

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http://dx.doi.org/10.1016/j.sbi.2006.08.009DOI Listing
October 2006

Immunology. Sugar determines antibody activity.

Science 2006 Aug;313(5787):627-8

Department of Immunology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/science.1131712DOI Listing
August 2006

Determining the structure of oligosaccharides N- and O-linked to glycoproteins.

Curr Protoc Protein Sci 2006 Mar;Chapter 12:Unit 12.6

University of Oxford, Oxford, United Kingdom.

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March 2006

Determining the structure of glycan moieties by mass spectrometry.

Curr Protoc Protein Sci 2006 Mar;Chapter 12:Unit 12.7

University of Oxford, Oxford, United Kingdom.

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March 2006