Ravindra Uppaluri

Ravindra Uppaluri

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Ravindra Uppaluri

Ravindra Uppaluri

Publications by authors named "Ravindra Uppaluri"

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55Publications

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Neoadjuvant PD-1 Immune Checkpoint Blockade Reverses Functional Immunodominance among Tumor Antigen-Specific T Cells.

Clin Cancer Res 2020 Feb 23;26(3):679-689. Epub 2019 Oct 23.

Translational Tumor Immunology Program, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-2209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002203PMC
February 2020

Targeting EZH2 Enhances Antigen Presentation, Antitumor Immunity, and Circumvents Anti-PD-1 Resistance in Head and Neck Cancer.

Clin Cancer Res 2020 Jan 27;26(1):290-300. Epub 2019 Sep 27.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942613PMC
January 2020

Disparities in Oral Cancer Screening Among Dental Professionals: NHANES 2011-2016.

Am J Prev Med 2019 Oct 20;57(4):447-457. Epub 2019 Aug 20.

Division of Oral Medicine, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.amepre.2019.04.026DOI Listing
October 2019

Radiologic predictors of immune checkpoint inhibitor response in advanced head and neck squamous cell carcinoma.

Oral Oncol 2018 10 17;85:29-34. Epub 2018 Aug 17.

Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA 703-389-1895, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13688375183029
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http://dx.doi.org/10.1016/j.oraloncology.2018.08.005DOI Listing
October 2018

Oral Cavity Squamous Cell Carcinoma Xenografts Retain Complex Genotypes and Intertumor Molecular Heterogeneity.

Cell Rep 2018 08;24(8):2167-2178

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA; Department of Medicine, Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63108, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183116
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http://dx.doi.org/10.1016/j.celrep.2018.07.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417872PMC
August 2018

CD271 Confers an Invasive and Metastatic Phenotype of Head and Neck Squamous Cell Carcinoma through the Upregulation of Slug.

Clin Cancer Res 2018 02 5;24(3):674-683. Epub 2017 Dec 5.

Division of Head and Neck Surgery, Department of Otolaryngology, Stanford Cancer Institute, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713647PMC
February 2018

Rationale for neoadjuvant immunotherapy in head and neck squamous cell carcinoma.

Oral Oncol 2017 10 17;73:65-69. Epub 2017 Aug 17.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Division of Otolaryngology-Head & Neck Surgery, Brigham & Women's Hospital, 75 Francis Street, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2017.08.008DOI Listing
October 2017

Checkpoint immunotherapy in head and neck cancers.

Cancer Metastasis Rev 2017 09;36(3):475-489

Brigham and Women's Hospital and Dana-Farber Cancer Institute, 45 Francis Street, Boston, MA, 02215, USA.

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http://link.springer.com/10.1007/s10555-017-9694-9
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http://dx.doi.org/10.1007/s10555-017-9694-9DOI Listing
September 2017

Neoantigens in immunotherapy and personalized vaccines: Implications for head and neck squamous cell carcinoma.

Oral Oncol 2017 08 14;71:169-176. Epub 2016 Oct 14.

Department of Otolaryngology, Washington University School of Medicine, St. Louis, United States; Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2016.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423853PMC
August 2017

Retropharyngeal Mass.

JAMA Otolaryngol Head Neck Surg 2017 04;143(4):421-422

Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoto.2016.3008DOI Listing
April 2017

nab-Paclitaxel, cisplatin, and 5-fluorouracil followed by concurrent cisplatin and radiation for head and neck squamous cell carcinoma.

Oral Oncol 2016 10 29;61:1-7. Epub 2016 Jul 29.

Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, United States; Department of Otolaryngology, Washington University School of Medicine, St. Louis, MO, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2016.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105832PMC
October 2016

Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers.

Cancer Immunol Res 2016 07 13;4(7):611-20. Epub 2016 Apr 13.

Tumor Biology Section, Head and Neck Surgery Branch, National Institutes of Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930724PMC
July 2016

Head and neck cancer immunology and immunotherapeutics: Basic concepts to clinical translational approaches.

Oral Oncol 2016 07 26;58:49-51. Epub 2016 May 26.

Division of Head and Neck Surgery, Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2016.05.004DOI Listing
July 2016

mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer.

Oncotarget 2015 Nov;6(34):36400-17

Tumor Biology Section, Head and Neck Surgery Branch, National Institutes of Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.18632/oncotarget.5063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742185PMC
November 2015

Ethmoid sinus mass. Sinonasal teratocarcinosarcoma.

JAMA Otolaryngol Head Neck Surg 2015 Apr;141(4):389-90

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri3Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.

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http://dx.doi.org/10.1001/jamaoto.2015.22DOI Listing
April 2015

Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer.

Genom Data 2015 Mar;3:61-62

Department of Otolaryngology and The Genome Institute, Washington University in Saint Louis School of Medicine, Department of Otolaryngology.

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https://linkinghub.elsevier.com/retrieve/pii/S22135960140011
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http://dx.doi.org/10.1016/j.gdata.2014.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340082PMC
March 2015

CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.

Oncotarget 2014 Aug;5(16):6854-66

Division of Head and Neck Surgery, Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA. Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA. Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196168PMC
http://dx.doi.org/10.18632/oncotarget.2269DOI Listing
August 2014

A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.

Clin Cancer Res 2014 Jun 25;20(11):2873-84. Epub 2014 Mar 25.

Authors' Affiliations: Departments of Cell Biology and Physiology, Otolaryngology, Genetics, Pathology and Immunology, and Neurosurgery; The Genome Institute, Washington University School of Medicine; and John Cochran VA Medical Center, St. Louis, MissouriAuthors' Affiliations: Departments of Cell Biology and Physiology, Otolaryngology, Genetics, Pathology and Immunology, and Neurosurgery; The Genome Institute, Washington University School of Medicine; and John Cochran VA Medical Center, St. Louis, Missouri

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096804PMC
June 2014

Emerging insights into head and neck cancer metastasis.

Head Neck 2013 Nov 22;35(11):1669-78. Epub 2012 Dec 22.

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1002/hed.23202DOI Listing
November 2013

Comparative analysis of tumor-infiltrating lymphocytes in a syngeneic mouse model of oral cancer.

Otolaryngol Head Neck Surg 2012 Sep 19;147(3):493-500. Epub 2012 Mar 19.

Department of Otolaryngology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1177/0194599812442037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346425PMC
September 2012

ERK1/2 regulation of CD44 modulates oral cancer aggressiveness.

Cancer Res 2012 Jan 15;72(1):365-74. Epub 2011 Nov 15.

Department of Otolaryngology and John Cochran VA Medical Center, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286642PMC
January 2012

The clinical implications of antitumor immunity in head and neck cancer.

Laryngoscope 2012 Jan;122(1):144-57

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/lary.21913DOI Listing
January 2012

Endoscopic surgical management of vidian nerve schwannoma.

Laryngoscope 2011 Feb 13;121(2):241-4. Epub 2011 Jan 13.

Department of Otolaryngology/Head and Neck Surgery, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1002/lary.21285DOI Listing
February 2011

Novel application of the palatal island flap for endoscopic skull base reconstruction.

Laryngoscope 2009 Aug;119(8):1463-6

Department of Otolaryngology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/lary.20298DOI Listing
August 2009

Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in head and neck cancers.

Cancer Immun 2008 Dec 4;8:16. Epub 2008 Dec 4.

Department of Otolaryngology/Head and Neck Surgery and John Cochran VA Medical Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935779PMC
December 2008

Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody.

Transplantation 2008 Jul;86(1):137-47

Department of Otolaryngology, Washington University School of Medicine and John Cochran VA Medical Center, St. Louis, MO, USA.

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http://dx.doi.org/10.1097/TP.0b013e31817b8e4bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140461PMC
July 2008

Pathology quiz case 2. Atypical meningioma with clear cell features (World Health Organization [WHO] grade II).

Arch Otolaryngol Head Neck Surg 2008 Apr;134(4):447-9

Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1001/archotol.134.4.447DOI Listing
April 2008

Spontaneous regression of cutaneous head and neck melanoma: implications for the immunologic control of neoplasia.

Head Neck 2008 Feb;30(2):267-72

Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/hed.20701DOI Listing
February 2008

Mycotic pseudoaneurysm of the internal maxillary artery: case report and review of the literature.

Arch Otolaryngol Head Neck Surg 2007 Apr;133(4):402-6

Medical Scientist Training Program, Washington University School of Medicine, St Louis, MO, USA.

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http://archotol.ama-assn.org/cgi/reprint/133/4/402.pdf
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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archotol.133.4.402DOI Listing
April 2007

Comparative analysis of regulatory and effector T cells in progressively growing versus rejecting tumors of similar origins.

Cancer Res 2006 Jul;66(14):7301-9

Center for Immunology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0556DOI Listing
July 2006

Association of reflux with otitis media in children.

Otolaryngol Head Neck Surg 2005 Sep;133(3):357-61

Department of Otolaryngology--Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.otohns.2005.05.654DOI Listing
September 2005

A critical function for type I interferons in cancer immunoediting.

Nat Immunol 2005 Jul 12;6(7):722-9. Epub 2005 Jun 12.

Department of Pathology and Immunology, Center for Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/ni1213DOI Listing
July 2005

IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation.

J Immunol 2002 Dec;169(11):6079-83

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.169.11.6079DOI Listing
December 2002