Ravindra Majeti

Ravindra Majeti

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Ravindra Majeti

Publications by authors named "Ravindra Majeti"

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Data mining for mutation-specific targets in acute myeloid leukemia.

Leukemia 2019 04 6;33(4):826-843. Epub 2019 Feb 6.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/articles/s41375-019-0387-y
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http://dx.doi.org/10.1038/s41375-019-0387-yDOI Listing
April 2019

Induced pluripotent stem cell modeling of malignant hematopoiesis.

Exp Hematol 2019 03 16;71:68-76. Epub 2019 Jan 16.

Department of Medicine, Division of Hematology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2019.01.002DOI Listing
March 2019

No Matter How You Splice It, RBM39 Inhibition Targets Spliceosome Mutant AML.

Cancer Cell 2019 Mar;35(3):337-339

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108193010
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http://dx.doi.org/10.1016/j.ccell.2019.02.013DOI Listing
March 2019

Targeting Cancer Stemness in the Clinic: From Hype to Hope.

Cell Stem Cell 2019 01 27;24(1):25-40. Epub 2018 Dec 27.

Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH 44192, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.11.017DOI Listing
January 2019

CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma.

N Engl J Med 2018 Nov;379(18):1711-1721

From Stanford University, Stanford (R.A., T.T., R.M., I.L.W.), City of Hope, Duarte (L.P.), and Forty Seven, Menlo Park (J.L., J.Y.C., J.-P.V., B.A., J.H., R.M., I.L.W., C.H.T., M.P.C.) - all in California; Sarah Cannon Research Institute-Tennessee Oncology, Nashville (I.F.); University of Alabama at Birmingham, Birmingham (A.F.); Washington University in St. Louis, St. Louis (N.L.B.); Levine Cancer Institute-Atrium Health, Charlotte, NC (N.G.); University of Chicago, Chicago (J.K., S.M.S.); National Cancer Institute, Rockville, MD (M.R.); Dana-Farber Cancer Institute, Boston (A.L.); and University of Oxford, Oxford, United Kingdom (G.P.C.).

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http://dx.doi.org/10.1056/NEJMoa1807315DOI Listing
November 2018

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

Cell 2018 05 26;173(6):1535-1548.e16. Epub 2018 Apr 26.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Applied Physics, Stanford University, Stanford, CA 94025, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989727PMC
May 2018

Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia.

Front Oncol 2017 6;7:263. Epub 2017 Nov 6.

Program in Cancer Biology, Cancer Institute, Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center, Stanford University School of Medicine, Stanford, CA, United States.

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http://journal.frontiersin.org/article/10.3389/fonc.2017.002
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http://dx.doi.org/10.3389/fonc.2017.00263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681525PMC
November 2017

Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.

Nat Protoc 2017 Oct 21;12(10):2169-2188. Epub 2017 Sep 21.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nprot.2017.088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898606PMC
October 2017

Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.

PLoS One 2016 18;11(7):e0159189. Epub 2016 Jul 18.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159189PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948781PMC
July 2017

Optimizing Next-Generation AML Therapy: Activity of Mutant IDH2 Inhibitor AG-221 in Preclinical Models.

Cancer Discov 2017 05;7(5):459-461

Division of Hematology, Department of Medicine, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456121PMC
May 2017

Biology and relevance of human acute myeloid leukemia stem cells.

Blood 2017 03 3;129(12):1577-1585. Epub 2017 Feb 3.

Division of Hematology, Department of Medicine, Cancer Institute and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1182/blood-2016-10-696054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364335PMC
March 2017

The role of mutations in the cohesin complex in acute myeloid leukemia.

Int J Hematol 2017 Jan 28;105(1):31-36. Epub 2016 Oct 28.

Division of Hematology, Department of Medicine, Cancer Institute, Stanford University School of Medicine, Stanford, USA.

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http://dx.doi.org/10.1007/s12185-016-2119-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516647PMC
January 2017

Sticking It to the Niche: CD98 Mediates Critical Adhesive Signals in AML.

Cancer Cell 2016 11;30(5):662-664

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.10.014DOI Listing
November 2016

SIRPα-Antibody Fusion Proteins Selectively Bind and Eliminate Dual Antigen-Expressing Tumor Cells.

Clin Cancer Res 2016 Oct 28;22(20):5109-5119. Epub 2016 Apr 28.

Division of Hematology, Department of Medicine, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2503DOI Listing
October 2016

Burning Fat Fuels Leukemic Stem Cell Heterogeneity.

Cell Stem Cell 2016 07;19(1):1-2

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.06.014DOI Listing
July 2016

A bispecific antibody targeting CD47 and CD20 selectively binds and eliminates dual antigen expressing lymphoma cells.

MAbs 2015 ;7(5):946-56

a Department of Medicine; Division of Hematology, Cancer Institute; and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University , Stanford , CA , USA.

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http://dx.doi.org/10.1080/19420862.2015.1062192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623422PMC
June 2016

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential.

PLoS One 2015 21;10(9):e0137345. Epub 2015 Sep 21.

Institute for Stem Cell Biology and Regenerative Medicine and the Ludwig Cancer Center, Stanford University School of Medicine, Stanford, California, United States of America; Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137345PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577081PMC
May 2016

Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia.

Exp Hematol 2015 Dec 9;43(12):989-92. Epub 2015 Oct 9.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical School, Stanford, California.

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http://dx.doi.org/10.1016/j.exphem.2015.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492948PMC
December 2015

Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.

Cell Stem Cell 2015 Dec 22;17(6):675-688. Epub 2015 Oct 22.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671831PMC
December 2015

An LSC epigenetic signature is largely mutation independent and implicates the HOXA cluster in AML pathogenesis.

Nat Commun 2015 Oct 7;6:8489. Epub 2015 Oct 7.

Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://www.nature.com/articles/ncomms9489
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http://dx.doi.org/10.1038/ncomms9489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633733PMC
October 2015

Clonal evolution of pre-leukemic hematopoietic stem cells precedes human acute myeloid leukemia.

Authors:
Ravindra Majeti

Best Pract Res Clin Haematol 2014 Sep-Dec;27(3-4):229-34. Epub 2014 Oct 15.

Department of Internal Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2014.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419218PMC
July 2015

Reply to Fišer et al.: Myeloid reprogramming of Ph+ B-ALL: A potential therapeutic strategy.

Proc Natl Acad Sci U S A 2015 Jul 11;112(27):E3456. Epub 2015 Jun 11.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1509027112
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http://dx.doi.org/10.1073/pnas.1509027112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500202PMC
July 2015

Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells.

Semin Hematol 2015 Jul 18;52(3):150-64. Epub 2015 Mar 18.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2015.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516648PMC
July 2015

Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands.

Cell 2015 Mar 26;160(6):1196-208. Epub 2015 Feb 26.

Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766813PMC
March 2015

Reprogramming of primary human Philadelphia chromosome-positive B cell acute lymphoblastic leukemia cells into nonleukemic macrophages.

Proc Natl Acad Sci U S A 2015 Mar 16;112(13):4074-9. Epub 2015 Mar 16.

Departments of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, and

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http://www.pnas.org/lookup/doi/10.1073/pnas.1413383112
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http://dx.doi.org/10.1073/pnas.1413383112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386392PMC
March 2015

Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia.

Nat Med 2015 Feb 19;21(2):178-84. Epub 2015 Jan 19.

1] Department of Medicine, Stanford University School of Medicine, Stanford, California, USA. [2] Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nm.3788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406275PMC
February 2015

Refractory warm IgM-mediated autoimmune hemolytic anemia associated with Churg-Strauss syndrome responsive to eculizumab and rituximab.

Am J Hematol 2015 Jan 11;90(1):78-81. Epub 2014 Jul 11.

Division of Hematology, Department of Medicine, Stanford University Medical Center, Stanford, California.

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http://dx.doi.org/10.1002/ajh.23791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435183PMC
January 2015

Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.

Blood 2015 Jan 14;125(2):316-26. Epub 2014 Nov 14.

Division of Hematology, Department of Medicine, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA;

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http://www.bloodjournal.org/content/bloodjournal/125/2/316.f
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-03-56
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http://dx.doi.org/10.1182/blood-2014-03-566018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287638PMC
January 2015

Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms.

PLoS One 2014 21;9(3):e92641. Epub 2014 Mar 21.

Department of Biology, Stanford University, Stanford, California, United States of America; Department of Genetics, Stanford School of Medicine, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092641PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962438PMC
November 2014

Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells.

Blood 2014 Jul 21;124(4):579-89. Epub 2014 May 21.

Department of Medicine, Stanford Cancer Institute, and.

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http://dx.doi.org/10.1182/blood-2013-12-544726DOI Listing
July 2014

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission.

Proc Natl Acad Sci U S A 2014 Feb 3;111(7):2548-53. Epub 2014 Feb 3.

Program in Cancer Biology, Ludwig Center, Cancer Institute, Institute for Stem Cell Biology and Regenerative Medicine, and Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1324297111
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http://dx.doi.org/10.1073/pnas.1324297111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932921PMC
February 2014

Role of DNMT3A, TET2, and IDH1/2 mutations in pre-leukemic stem cells in acute myeloid leukemia.

Int J Hematol 2013 Dec 15;98(6):648-57. Epub 2013 Aug 15.

Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Palo Alto, CA, 94305, USA.

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http://dx.doi.org/10.1007/s12185-013-1407-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542003PMC
December 2013

The cancer stem cell model: B cell acute lymphoblastic leukaemia breaks the mould.

EMBO Mol Med 2013 01 11;5(1):7-9. Epub 2012 Dec 11.

Department of Medicine, Division of Hematology, Institute for Stem Cell Biology and Regenerative Medicine, and Cancer Institute, Stanford University School of Medicine, Palo Alto, CA, USA.

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http://dx.doi.org/10.1002/emmm.201202207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569649PMC
January 2013

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

Sci Transl Med 2012 Aug;4(149):149ra118

Program in Cancer Biology, Cancer Institute, Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center, Stanford University School of Medicine, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1126/scitranslmed.3004315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045621PMC
August 2012

The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications.

Curr Opin Immunol 2012 Apr 4;24(2):225-32. Epub 2012 Feb 4.

Institute for Stem Cell Biology and Regenerative Medicine and Cancer Institute, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.coi.2012.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319521PMC
April 2012

Treatment advances have not improved the early death rate in acute promyelocytic leukemia.

Haematologica 2012 Jan 11;97(1):133-6. Epub 2011 Oct 11.

Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305-5821, USA.

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http://dx.doi.org/10.3324/haematol.2011.046490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248942PMC
January 2012

Programmed cell removal: a new obstacle in the road to developing cancer.

Nat Rev Cancer 2011 Dec 8;12(1):58-67. Epub 2011 Dec 8.

Institute for Stem Cell Biology and Regenerative Medicine and Cancer Institute, Division of Haematology, Stanford University School of Medicine, Lokey Stem Cell Research Building, 265 Campus Drive, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nrc3171DOI Listing
December 2011

Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy.

Blood 2011 Nov 9;118(18):4890-901. Epub 2011 Aug 9.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cancer Center, and Ludwig Center at Stanford, Stanford, CA, USA.

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http://dx.doi.org/10.1182/blood-2011-02-338020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208297PMC
November 2011

Surprise! HSC are aberrant in chronic lymphocytic leukemia.

Cancer Cell 2011 Aug;20(2):135-6

Institute for Stem Cell Biology and Regenerative Medicine, Cancer Institute, and Division of Hematology, Department of Internal Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.08.001DOI Listing
August 2011

Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.

Blood 2011 Apr 28;117(16):4226-33. Epub 2011 Feb 28.

Program in Immunology, Stanford University School of Medicine, Stanford, CA, USA; Baxter Laboratories for Stem Cell Biology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1182/blood-2010-07-298232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087474PMC
April 2011

Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker.

Proc Natl Acad Sci U S A 2011 Mar 7;108(12):5009-14. Epub 2011 Mar 7.

Program in Cancer Biology, Cancer Center, Institute for Stem Cell Biology and Regenerative Medicine, Department of Internal Medicine, Stanford University School of Medicine, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.1100551108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064328PMC
March 2011

Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.

Cancer Res 2011 Feb 21;71(4):1374-84. Epub 2010 Dec 21.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cancer Center, and Ludwig Center at Stanford, Palo Alto, California, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-10-2238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041855PMC
February 2011

Human acute myelogenous leukemia stem cells revisited: there's more than meets the eye.

Cancer Cell 2011 Jan;19(1):9-10

Department of Internal Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045274PMC
January 2011

Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.

JAMA 2010 Dec;304(24):2706-15

Department of Radiology, Lucas Center for MR Spectroscopy and Imaging, School of Medicine, Stanford University, Palo Alto, CA 94305, USA.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2010.1862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089862PMC
December 2010

Macrophages as mediators of tumor immunosurveillance.

Trends Immunol 2010 Jun 7;31(6):212-9. Epub 2010 May 7.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford Cancer Center, and Ludwig Center at Stanford, USA.

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http://www.cell.com/trends/immunology/pdf/S1471-4906(10)0005
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http://linkinghub.elsevier.com/retrieve/pii/S147149061000052
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http://dx.doi.org/10.1016/j.it.2010.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646798PMC
June 2010

Metastatic cancer stem cells: an opportunity for improving cancer treatment?

Cell Stem Cell 2010 Jun;6(6):502-3

Cancer Center, Stanford University School of Medicine, Palo Alto, CA 94305, USA.

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http://dx.doi.org/10.1016/j.stem.2010.05.001DOI Listing
June 2010

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.

Cell 2009 Jul;138(2):271-85

Ludwig Center at Stanford, Stanford Cancer Center, Department of Pathology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.cell.2009.05.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775564PMC
July 2009

In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood.

Nat Protoc 2008 ;3(12):1932-40

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 1050 Arastradero Road, Palo Alto, California 94304, USA.

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http://dx.doi.org/10.1038/nprot.2008.194DOI Listing
April 2009

The adhesion molecule esam1 is a novel hematopoietic stem cell marker.

Stem Cells 2009 Mar;27(3):653-61

Institute of Stem Cell Biology and Regenerative Medicine, Department of Pathology, Stanford University School of Medicine, California, USA.

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http://doi.wiley.com/10.1634/stemcells.2008-0824
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http://dx.doi.org/10.1634/stemcells.2008-0824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186794PMC
March 2009

Dysregulated gene expression networks in human acute myelogenous leukemia stem cells.

Proc Natl Acad Sci U S A 2009 Mar 13;106(9):3396-401. Epub 2009 Feb 13.

Institute for Stem Cell Biology and Regenerative Medicine and Department of Internal Medicine, Division of Hematology, Stanford University, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1073/pnas.0900089106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642659PMC
March 2009

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood.

Cell Stem Cell 2007 Dec;1(6):635-45

Department of Internal Medicine, Division of Hematology, Stanford University, Palo Alto, CA 94304, USA.

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http://dx.doi.org/10.1016/j.stem.2007.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292126PMC
December 2007

The juxtamembrane wedge negatively regulates CD45 function in B cells.

Immunity 2005 Dec;23(6):635-47

Department of Pediatrics, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1016/j.immuni.2005.11.001DOI Listing
December 2005

Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases.

J Clin Invest 2002 Jan;109(1):9-14

Department of Pediatrics, The Howard Hughes Medical Institute, University of California, San Francisco, California 94143-0795, USA.

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http://dx.doi.org/10.1172/JCI14794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150828PMC
January 2002