Publications by authors named "Raul D Santos"

100Publications

Coronary Artery Calcification in Familial Hypercholesterolemia: An Opportunity for Risk Assessment and Shared Decision Making With the Power of Zero?

Circulation 2020 Oct 12;142(15):1405-1407. Epub 2020 Oct 12.

Hospital Israelita Albert Einstein, Sao Paulo, Brazil (R.D.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.049057DOI Listing
October 2020

Cardiovascular Risk and Statin Eligibility in Primary Prevention: A Comparison between the Brazilian and the AHA/ACC Guidelines.

Arq Bras Cardiol 2020 Sep;115(3):440-449

Hospital Israelita Albert Einstein, São Paulo, SP - Brasil.

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http://dx.doi.org/10.36660/abc.20190519DOI Listing
September 2020

Advances with lipid-lowering drugs for pediatric patients with familial hypercholesterolemia.

Expert Opin Pharmacother 2020 Oct 5. Epub 2020 Oct 5.

Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital , São Paulo, Brazil.

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http://dx.doi.org/10.1080/14656566.2020.1832991DOI Listing
October 2020

Differences in HDL particle size in the presence of subclinical thyroid dysfunctions: The ELSA-Brasil study.

Atherosclerosis 2020 Sep 11;312:60-65. Epub 2020 Sep 11.

Center for Clinical and Epidemiological Research, Hospital Universitário, Universidade de Sao Paulo, Sao Paulo, SP, Brazil; Department of Internal Medicine, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.08.021DOI Listing
September 2020

From the President of the International Atherosclerosis Society.

Authors:
Raul D Santos

J Clin Lipidol 2020 Aug 28. Epub 2020 Aug 28.

Lipid Clinic, Heart Institute (InCor), University of Sao Paulo Medical School Hospital, São Paulo, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2020.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455145PMC
August 2020

Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia.

N Engl J Med 2020 10 29;383(14):1317-1327. Epub 2020 Aug 29.

From the Lipid Clinic Heart Institute, University of São Paulo Medical School Hospital and Hospital Israelita Albert Einstein, São Paulo (R.D.S.); Amgen, Thousand Oaks, CA (A.R., C.E.K, A.H.); the Departments of Vascular Medicine (G.K.H., J.J.P.K.) and Pediatrics (A.W., I.L.), Amsterdam UMC, Amsterdam; the Cardiology Department, Geneva University Hospital, Geneva (F.M.); the Biostatistics Department, Amgen, Cambridge (I.B.), and the Department of Clinical Inherited Metabolic Disorders, Birmingham Children's Hospital, Birmingham (S.S.) - both in the United Kingdom; the Rare Diseases and Clinical Genetics Unit, Academic Pediatric Department, Bambino Gesù Children's Hospital (A.B.), and the Department of Molecular Medicine, Umberto I Hospital, Sapienza University of Rome (C.S.), Rome; the Lipid Clinic, Department of Medicine, Centre Hospitalier Universitaire de Québec-Université Laval, Quebec (J.B.), and the Clinical Lipidology and Rare Lipid Disorders Unit, Community Genomic Medicine Centre and ECOGENE-21, Department of Medicine, Université de Montréal, Chicoutimi, QC (D.G.) - both in Canada; the 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary (T.S.); the Department of Internal Medicine, Centres Hospitaliers Jolimont, La Louvière, Belgium (O.S.D.); and the Division of Pediatric Pulmonology, Allergology, and Endocrinology, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna (S.G.-P.).

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http://dx.doi.org/10.1056/NEJMoa2019910DOI Listing
October 2020

The Role of Statins in Current Guidelines.

Curr Atheroscler Rep 2020 Aug 8;22(9):50. Epub 2020 Aug 8.

Heart Institute-InCor, University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil.

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http://dx.doi.org/10.1007/s11883-020-00861-9DOI Listing
August 2020

Prognostic utility of triglyceride-rich lipoprotein-related markers in patients with coronary artery disease.

J Lipid Res 2020 Sep 8;61(9):1254-1262. Epub 2020 Jul 8.

State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China

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http://dx.doi.org/10.1194/jlr.RA120000746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469882PMC
September 2020

Association of Omnivorous and Vegetarian Diets With Antioxidant Defense Mechanisms in Men.

J Am Heart Assoc 2020 Jun 9;9(12):e015576. Epub 2020 Jun 9.

Institute of Biosciences São Paulo State University - IBB/UNESP Botucatu, São Paulo Brazil.

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http://dx.doi.org/10.1161/JAHA.119.015576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429062PMC
June 2020

Does physical activity influence the association between depressive symptoms and low-grade inflammation in adults? A study of 8,048 adults.

Physiol Behav 2020 09 29;223:112967. Epub 2020 May 29.

Hospital Israelita Albert Einstein, Sao Paulo, Brazil; Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, Brazil.; Center for Clinical and Epidemiological Research, University Hospital, University of Sao Paulo, Sao Paulo, Brazil.

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http://dx.doi.org/10.1016/j.physbeh.2020.112967DOI Listing
September 2020

Self-initiated changes in physical activity and incidence of Metabolic Syndrome: A longitudinal follow-up study.

Diabetes Res Clin Pract 2020 Jul 28;165:108224. Epub 2020 May 28.

Hospital Israelita Albert Einstein, Sao Paulo, Brazil; Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, Brazil.

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http://dx.doi.org/10.1016/j.diabres.2020.108224DOI Listing
July 2020

EUROASPIRE V and uncontrolled risk factors in primary prevention: Atherosclerotic cardiovascular disease in the making.

Authors:
Raul D Santos

Eur J Prev Cardiol 2020 Apr 1:2047487320915662. Epub 2020 Apr 1.

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Brazil.

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http://dx.doi.org/10.1177/2047487320915662DOI Listing
April 2020

Long-Term Evolocumab in Patients With Familial Hypercholesterolemia.

J Am Coll Cardiol 2020 02;75(6):565-574

Carbohydrate and Lipid Metabolism Research Unit, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1016/j.jacc.2019.12.020DOI Listing
February 2020

Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care.

Nat Rev Cardiol 2020 06 23;17(6):360-377. Epub 2020 Jan 23.

Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41569-019-0325-8DOI Listing
June 2020

Absence of coronary artery calcification and low rates not only of coronary and cardiovascular mortality: Can the power of zero be expanded beyond the vessels?

Authors:
Raul D Santos

Atherosclerosis 2020 02 25;294:44-45. Epub 2019 Dec 25.

Heart Institute (InCor) University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.12.019DOI Listing
February 2020

Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action.

JAMA Cardiol 2020 Feb;5(2):217-229

Familial Hypercholesterolemia Foundation, Pasadena, California.

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http://dx.doi.org/10.1001/jamacardio.2019.5173DOI Listing
February 2020

Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes.

Atherosclerosis 2020 01 28;293:49-56. Epub 2019 Nov 28.

L'institut Du Thorax, INSERM, CNRS, UNIV Nantes, Nantes, France; L'institut Du Thorax, Department of Endocrinology, CIC 1413 INSERM, CHU Nantes, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.11.027DOI Listing
January 2020

Very high LDL cholesterol: The power of zero passes another test.

Atherosclerosis 2020 01 17;292:207-208. Epub 2019 Nov 17.

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.11.019DOI Listing
January 2020

Lomitapide and Mipomersen-Inhibiting Microsomal Triglyceride Transfer Protein (MTP) and apoB100 Synthesis.

Curr Atheroscler Rep 2019 11 19;21(12):48. Epub 2019 Nov 19.

Division of Chemical Pathology, University of Cape Town Health Science Faculty, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s11883-019-0809-3DOI Listing
November 2019

Vascular age derived from coronary artery calcium score on the risk stratification of individuals with heterozygous familial hypercholesterolaemia.

Eur Heart J Cardiovasc Imaging 2020 Mar;21(3):251-257

Heart Institute (InCor), University of São Paulo Medical School Hospital, Av. Dr Eneas C Aguiar 44, 05403900, São Paulo, Brazil.

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http://dx.doi.org/10.1093/ehjci/jez280DOI Listing
March 2020

High-density Lipoprotein-cholesterol Subfractions and Coronary Artery Calcium: The ELSA-Brasil Study.

Arch Med Res 2019 08 31;50(6):362-367. Epub 2019 Oct 31.

Instituto do Coracao, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil; Center for Clinical and Epidemiological Research, University Hospital, University of Sao Paulo, Sao Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.arcmed.2019.10.006DOI Listing
August 2019

Reducing cardiovascular risk in patients with familial hypercholesterolemia: Risk prediction and lipid management.

Prog Cardiovasc Dis 2019 Sep - Oct;62(5):414-422. Epub 2019 Oct 25.

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.pcad.2019.10.003DOI Listing
January 2020

Predicting intention to participate in self-management behaviors in patients with Familial Hypercholesterolemia: A cross-national study.

Soc Sci Med 2019 12 7;242:112591. Epub 2019 Oct 7.

School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia; Lipid Disorders Clinic, Cardiometabolic Service, Department of Cardiology, Royal Perth Hospital, Perth, Australia.

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http://dx.doi.org/10.1016/j.socscimed.2019.112591DOI Listing
December 2019

Plasma proprotein convertase subtilisin/kexin type 9 concentration and recurrent cardiovascular events in patients with familial hypercholesterolemia.

Eur J Prev Cardiol 2019 Oct 11:2047487319880985. Epub 2019 Oct 11.

State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital and National Center for Cardiovascular Diseases, China.

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http://dx.doi.org/10.1177/2047487319880985DOI Listing
October 2019

SPPARM alpha: the Lazarus effect.

Curr Opin Lipidol 2019 12;30(6):419-427

Hospital Israelita Albert Einstein.

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http://dx.doi.org/10.1097/MOL.0000000000000640DOI Listing
December 2019

Bringing interleukin-6 complexity to preventive cardiology practice?

Eur J Prev Cardiol 2020 01 19;27(2):119-121. Epub 2019 Sep 19.

Heart Institute InCor, University of São Paulo Medical School Hospital, Brazil.

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http://dx.doi.org/10.1177/2047487319876765DOI Listing
January 2020

Update on genetics and molecular biology.

Curr Opin Lipidol 2019 10;30(5):414-416

Heart Institute (InCor), University of São Paulo Medical School Hospital.

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http://dx.doi.org/10.1097/MOL.0000000000000633DOI Listing
October 2019

Residual vascular risk in diabetes - Will the SPPARM alpha concept hold the key?

Diabetes Metab Syndr 2019 Jul - Aug;13(4):2723-2725. Epub 2019 May 30.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.dsx.2019.05.034DOI Listing
February 2020

Screening and management of familial hypercholesterolemia.

Authors:
Raul D Santos

Curr Opin Cardiol 2019 09;34(5):526-530

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital.

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http://dx.doi.org/10.1097/HCO.0000000000000660DOI Listing
September 2019

Impact of improved low-density lipoprotein cholesterol assessment on guideline classification in the modern treatment era-Results from a racially diverse Brazilian cross-sectional study.

J Clin Lipidol 2019 Sep - Oct;13(5):804-811.e2. Epub 2019 Jul 9.

Ciccarone Center for the Prevention of Cardiovascular Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2019.07.002DOI Listing
July 2020

Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement.

Lancet Diabetes Endocrinol 2019 09 10;7(9):715-725. Epub 2019 Jul 10.

Division of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, CO, USA.

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http://dx.doi.org/10.1016/S2213-8587(19)30084-1DOI Listing
September 2019

Low-density lipoprotein cholesterol goal achievement in patients with familial hypercholesterolemia in countries outside Western Europe: The International ChoLesterol management Practice Study.

J Clin Lipidol 2019 Jul - Aug;13(4):594-600. Epub 2019 May 14.

Lipid Clinic, Heart Institute (InCor), University of Sao Paulo Medical School Hospital and Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1016/j.jacl.2019.05.004DOI Listing
June 2020

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Cardiovasc Diabetol 2019 06 4;18(1):71. Epub 2019 Jun 4.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12933-019-0864-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549355PMC
June 2019

HDL-cholesterol level and mortality occurrence in the elderly: is the good cholesterol always good?

J Clin Endocrinol Metab 2019 May 16. Epub 2019 May 16.

Lipid Clinic Heart Institute (InCor) University of Sao Paulo Medical School Hospital and Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1210/jc.2019-00845DOI Listing
May 2019

Distinct phospholipid and sphingolipid species are linked to altered HDL function in apolipoprotein A-I deficiency.

J Clin Lipidol 2019 May - Jun;13(3):468-480.e8. Epub 2019 Feb 25.

UMR-ICAN 1166, National Institute for Health and Medical Research (INSERM), Sorbonne University, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2019.02.004DOI Listing
May 2020

Baseline LDL-C levels and risk of cardiovascular events: is there any room for questions?

Int J Cardiol 2019 07 29;286:166-167. Epub 2019 Mar 29.

Lipid Clinic Heart Institute (InCor)-University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1016/j.ijcard.2019.03.058DOI Listing
July 2019

Case report: The efficacy and safety of lomitapide in a homozygous familial hypercholesterolemic child.

J Clin Lipidol 2019 May - Jun;13(3):397-401. Epub 2019 Mar 11.

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19332874193004
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http://dx.doi.org/10.1016/j.jacl.2019.03.001DOI Listing
May 2020

Comparative aspects of the care of familial hypercholesterolemia in the "Ten Countries Study".

J Clin Lipidol 2019 Mar - Apr;13(2):287-300. Epub 2019 Jan 25.

School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia; Department of Cardiology, Lipid Disorders Clinic, Cardiometabolic Services, Royal Perth Hospital, Perth, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2019.01.009DOI Listing
April 2020

Inadequate control of atherosclerotic cardiovascular disease risk factors in Europe: EUROASPIRE repeats itself.

Authors:
Raul D Santos

Eur J Prev Cardiol 2019 05 20;26(8):820-823. Epub 2019 Feb 20.

1 Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Brazil.

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http://journals.sagepub.com/doi/10.1177/2047487319831476
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http://dx.doi.org/10.1177/2047487319831476DOI Listing
May 2019

Does nonalcoholic fatty liver disease cause cardiovascular disease? Current knowledge and gaps.

Atherosclerosis 2019 03 30;282:110-120. Epub 2019 Jan 30.

Department of Molecular and Clinical Medicine Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.01.029DOI Listing
March 2019

Simon Broome confirms that the IAS definition of severe familial hypercholesterolemia predicts coronary mortality in patients with FH.

Atherosclerosis 2019 02 22;281:145-147. Epub 2018 Dec 22.

School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia; Lipid Disorders Clinic, Cardiometabolic Service, Department of Cardiology, Royal Perth Hospital, Perth, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.12.013DOI Listing
February 2019

Safety and efficacy of mipomersen in patients with heterozygous familial hypercholesterolemia.

Atherosclerosis 2019 01 10;280:109-117. Epub 2018 Nov 10.

Sections of Cardiology and Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.11.017DOI Listing
January 2019

Coronary Artery Calcium and Cardiovascular Events in Patients With Familial Hypercholesterolemia Receiving Standard Lipid-Lowering Therapy.

JACC Cardiovasc Imaging 2019 09 15;12(9):1797-1804. Epub 2018 Nov 15.

Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address:

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http://imaging.onlinejacc.org/content/early/recent
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https://linkinghub.elsevier.com/retrieve/pii/S1936878X183093
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http://dx.doi.org/10.1016/j.jcmg.2018.09.019DOI Listing
September 2019

Mendelian randomization causally link lipoproteins to systemic atherosclerosis and help design clinical trials for the future of lipidology.

Curr Opin Lipidol 2018 12;29(6):482-483

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital.

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http://dx.doi.org/10.1097/MOL.0000000000000557DOI Listing
December 2018

Beware of early drug intolerance in secondary prevention of cardiovascular disease.

Authors:
Raul D Santos

Eur Heart J Cardiovasc Pharmacother 2018 10;4(4):202-204

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil.

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https://academic.oup.com/ehjcvp/article/4/4/202/5059516
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http://dx.doi.org/10.1093/ehjcvp/pvy023DOI Listing
October 2018

Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia.

Atherosclerosis 2018 10;277:493-501

School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia; Lipid Disorders Clinic, Cardiometabolic Service, Department of Cardiology, Royal Perth Hospital, Perth, Australia.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.06.010DOI Listing
October 2018

Heterozygous familial hypercholesterolaemia in specialist centres in South Africa, Australia and Brazil: Importance of early detection and lifestyle advice.

Atherosclerosis 2018 10;277:470-476

School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia; Lipid Disorders Clinic, Cardiometabolic Services, Department of Cardiology, Royal Perth Hospital, Perth, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.06.822DOI Listing
October 2018

Health related quality of life in individuals at high risk for familial hypercholesterolemia undergoing genetic cascade screening in Brazil.

Atherosclerosis 2018 10;277:464-469

Heart Institute (InCor) University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil; Hospital Israelita Albert Einstein, Sao Paulo, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183027
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http://dx.doi.org/10.1016/j.atherosclerosis.2018.05.036DOI Listing
October 2018

Familial hypercholesterolemia prevalence in an admixed racial society: Sex and race matter. The ELSA-Brasil.

Atherosclerosis 2018 10;277:273-277

Center for Clinical and Epidemiological Research, University Hospital, University of Sao Paulo, 2565 Prof. Lineu Prestes Avenue, Sao Paulo, 05508-000, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.08.021DOI Listing
October 2018

Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC).

Atherosclerosis 2018 10;277:234-255

Imperial Centre for Cardiovascular Disease Prevention (ICCP), Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.08.051DOI Listing
October 2018

Epicardial adipose tissue thickness and type 2 diabetes risk according to the FINDRISC modified for Latin America.

Clin Investig Arterioscler 2019 Jan - Feb;31(1):15-22. Epub 2018 Aug 27.

Division of Endocrinology, Department of Medicine, University of Miami Miller School of Medicine, Miami, USA.

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http://dx.doi.org/10.1016/j.arteri.2018.06.002DOI Listing
June 2019

Predictors of Family Enrollment in a Genetic Cascade Screening Program for Familial Hypercholesterolemia.

Arq Bras Cardiol 2018 Oct 23;111(4):578-584. Epub 2018 Aug 23.

Laboratório de Genética e Cardiologia Molecular do Instituto do Coração (InCor) da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brazil.

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http://dx.doi.org/10.5935/abc.20180156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199512PMC
October 2018

Association between high-density lipoprotein subfractions and low-grade inflammation, insulin resistance, and metabolic syndrome components: The ELSA-Brasil study.

J Clin Lipidol 2018 Sep - Oct;12(5):1290-1297.e1. Epub 2018 May 26.

Center for Clinical and Epidemiological Research, University Hospital, University of São Paulo, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2018.05.003DOI Listing
October 2019

Estimated costs of hospitalization due to coronary artery disease attributable to familial hypercholesterolemia in the Brazilian public health system.

Arch Endocrinol Metab 2018 Jun 17;62(3):303-308. Epub 2018 May 17.

Departamento de Medicina Interna, Universidade do Estado do Rio de Janeiro (UERJ); Instituto de Avaliação de Tecnologia em Saúde (IATS), Rio de Janeiro, RJ, Brasil.

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http://dx.doi.org/10.20945/2359-3997000000030DOI Listing
June 2018

Cholesterol and inflammation: The lesser the better in atherothrombosis.

Eur J Prev Cardiol 2018 06 14;25(9):944-947. Epub 2018 May 14.

1 Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Brazil.

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http://dx.doi.org/10.1177/2047487318772936DOI Listing
June 2018

Statin Eligibility in Primary Prevention: From a Risk-Based Strategy to a Personalized Approach Based on the Predicted Benefit.

Am J Cardiol 2018 06 1;121(11):1315-1320. Epub 2018 Mar 1.

Preventive Medicine Center, Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil; Division of Internal Medicine, University Hospital, University of São Paulo, São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1016/j.amjcard.2018.02.011DOI Listing
June 2018

Prevalence, management, and outcomes of familial hypercholesterolemia in patients with acute coronary syndromes in the Arabian Gulf.

J Clin Lipidol 2018 May - Jun;12(3):685-692.e2. Epub 2018 Feb 14.

Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait city, Kuwait.

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http://dx.doi.org/10.1016/j.jacl.2018.02.003DOI Listing
September 2019

Self-initiated physical activity is associated with high sensitivity C-reactive protein: A longitudinal study in 5,030 adults.

Atherosclerosis 2018 06 8;273:131-135. Epub 2018 Feb 8.

Hospital Israelita Albert Einstein, Sao Paulo, Brazil; Faculdade Israelita de Ciências da Saúde Albert Einstein, Sao Paulo, Brazil.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183007
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http://dx.doi.org/10.1016/j.atherosclerosis.2018.02.011DOI Listing
June 2018

Expression of LDLRs (Low-Density Lipoprotein Receptors), Dyslipidemia Severity, and Response to PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Inhibition in Homozygous Familial Hypercholesterolemia: Connecting the Dots.

Authors:
Raul D Santos

Arterioscler Thromb Vasc Biol 2018 03;38(3):481-483

From the Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital, Brazil; and Preventive Medicine Centre and Cardiology Program, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1161/ATVBAHA.117.310675DOI Listing
March 2018

Safety of statin treatment in children with familial hypercholesterolemia: Filling the gaps.

J Clin Lipidol 2018 Jan - Feb;12(1):12-15. Epub 2017 Dec 7.

Lipid Clinic Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2017.11.007DOI Listing
April 2019

Familial hypercholesterolaemia.

Nat Rev Dis Primers 2017 Dec 7;3:17093. Epub 2017 Dec 7.

Metabolic Medicine and Chemical Pathology, Guy's and St. Thomas' Hospitals, London, UK.

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http://www.nature.com/articles/nrdp201793
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http://dx.doi.org/10.1038/nrdp.2017.93DOI Listing
December 2017

Genetics and molecular biology controversies on Mendelian randomization and proprotein convertase subtilisin-kexin type 9 inhibitor clinical trials: more data still necessary.

Authors:
Raul D Santos

Curr Opin Lipidol 2017 12;28(6):522-523

aLipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital bPreventive Medicine Center, Cardiology Program, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1097/MOL.0000000000000460DOI Listing
December 2017

Better health literacy can make the difference when control of risk factors for cardiovascular disease and quality of life are concerned.

Authors:
Raul D Santos

Eur J Prev Cardiol 2017 11 3;24(17):1878-1879. Epub 2017 Oct 3.

Lipid Clinic Heart Institute (InCor), University of Sao Paulo Medical School Hospital and Preventive Medicine Centre and Cardiology Program, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

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http://dx.doi.org/10.1177/2047487317735721DOI Listing
November 2017

Computed tomography angiography defined vulnerable plaque in a patient with low high-density lipoprotein cholesterol and subsequent myocardial infarction.

Coron Artery Dis 2017 12;28(8):712-714

aDepartment of Cardiology, Heart Institute (InCor), School of Medicine from University of São Paulo bDepartment of Cardiology, Hospital Israelita Albert Einstein, São Paulo, Brazil.

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http://dx.doi.org/10.1097/MCA.0000000000000524DOI Listing
December 2017