Publications by authors named "Rathi Ravindrarajah"

20Publications

Importance of Frailty for Association of Antipsychotic Drug Use With Risk of Fracture: Cohort Study Using Electronic Health Records.

J Am Med Dir Assoc 2019 12 1;20(12):1495-1501.e1. Epub 2019 Jul 1.

School of Population Health and Environmental Sciences, King's College London, London, United Kingdom; NIHR Biomedical Research Centre at Guy's and St Thomas' Hospitals London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2019.05.009DOI Listing
December 2019

Frailty: from clinical syndrome to epidemiological construct?

Lancet Public Health 2018 07 14;3(7):e305-e306. Epub 2018 Jun 14.

Centre for Primary Care, Division of Population Health, Health Services Research and Primary Care, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1016/S2468-2667(18)30112-9DOI Listing
July 2018

Inception and deprescribing of statins in people aged over 80 years: cohort study.

Age Ageing 2017 11;46(6):1001-1005

King's College London, Department of Primary Care and Public Health Sciences, London, UK.

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http://dx.doi.org/10.1093/ageing/afx100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669477PMC
November 2017

"Progressive dwindling" or "terminal decline" and end of life care.

BMJ 2017 10 19;359:j4772. Epub 2017 Oct 19.

King's College London, School of Population Health Sciences, London WC2R 2LS, UK.

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http://dx.doi.org/10.1136/bmj.j4772DOI Listing
October 2017

Trajectory of Total Cholesterol in the Last Years of Life Over Age 80 Years: Cohort Study of 99,758 Participants.

J Gerontol A Biol Sci Med Sci 2018 07;73(8):1083-1089

Department of Primary Care and Public Health Sciences, King's College London, UK.

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http://dx.doi.org/10.1093/gerona/glx184DOI Listing
July 2018

Declining blood pressure and intensification of blood pressure management among people over 80 years: cohort study using electronic health records.

J Hypertens 2017 06;35(6):1276-1282

aDepartment of Primary Care and Public Health Sciences, Kings College LondonbNational Institute for Health Research Biomedical Research Centre at Guy's and St Thomas' National Health Service Foundation TrustcDepartment of Clinical Gerontology, King's College London, London, UK.

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http://dx.doi.org/10.1097/HJH.0000000000001291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404403PMC
June 2017

Systolic Blood Pressure Trajectory, Frailty, and All-Cause Mortality >80 Years of Age: Cohort Study Using Electronic Health Records.

Circulation 2017 Jun 21;135(24):2357-2368. Epub 2017 Apr 21.

From Department of Primary Care and Public Health Sciences (R.R., N.C.H., S.H., J.C., A.D., M.C.G.), Department of Clinical Gerontology (J.C., S.H.D.J.), King's College London, UK; Research Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan (S.H.); and National Institute for Health Research Biomedical Research Centre at Guy's and St Thomas' National Health Service Foundation Trust, London, UK (A.D., M.C.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472195PMC
June 2017

Frailty and bone health in European men.

Age Ageing 2017 07;46(4):635-641

Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal & Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/ageing/afw205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859977PMC
July 2017

Longitudinal Trends in Hypertension Management and Mortality Among Octogenarians: Prospective Cohort Study.

Hypertension 2016 07 9;68(1):97-105. Epub 2016 May 9.

From the Department of Primary Care and Public Health (A.D., R.R., N.H., S.H., M.C.G.), National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' National Health Service Foundation Trust (A.D., M.C.G.), and Department of Clinical Gerontology (S.H.D.J.), King's College London, London, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900418PMC
July 2016

Chronic widespread pain is associated with worsening frailty in European men.

Age Ageing 2016 Mar 17;45(2):268-74. Epub 2015 Dec 17.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust-Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/ageing/afv170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776622PMC
March 2016

Low testosterone in ageing men: a modifiable risk factor for frailty?

Trends Endocrinol Metab 2011 Dec 4;22(12):491-8. Epub 2011 Oct 4.

Andrology Research Unit, Developmental and Regenerative Biomedicine Research Group, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester Royal Infirmary, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1016/j.tem.2011.08.003DOI Listing
December 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

Linkage of monogenic infantile hypertrophic pyloric stenosis to chromosome 16p12-p13 and evidence for genetic heterogeneity.

Am J Hum Genet 2006 Aug 7;79(2):378-82. Epub 2006 Jun 7.

Department of Paediatrics and Child Health, The Rayne Building, University College London, WC1E 6JJ London, UK.

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http://dx.doi.org/10.1086/505952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559485PMC
August 2006