Rasika A Mathias

Rasika A Mathias

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Rasika A Mathias

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The relationship of family history and risk of type 2 diabetes differs by ancestry.

Diabetes Metab 2019 06 21;45(3):261-267. Epub 2018 May 21.

The Johns Hopkins GeneSTAR Research Program, Department of Medicine, The Johns Hopkins Medical Institutions, 1830, East Monument Street, Room 8023, 21287 Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.diabet.2018.05.004DOI Listing
June 2019

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families.

Platelets 2019 19;30(3):380-386. Epub 2018 Mar 19.

a GeneSTAR Research Program Department of Medicine, Division of General Internal Medicine , Johns Hopkins University School of Medicine , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/09537104.2018.1447659DOI Listing
April 2019

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

J Allergy Clin Immunol 2019 Mar 7;143(3):957-969. Epub 2018 Sep 7.

Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, Calif; Department of Medicine, University of California, San Francisco, San Francisco, Calif.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183127
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http://dx.doi.org/10.1016/j.jaci.2016.08.057DOI Listing
March 2019

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 02 20;10(1):880. Epub 2019 Feb 20.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-08469-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382865PMC
February 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.

Stroke 2018 08;49(8):1812-1819

From the Institute of Molecular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston (M.F., X.J.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202149PMC
August 2018

Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression.

PLoS One 2018 28;13(3):e0194610. Epub 2018 Mar 28.

Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194610PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874031PMC
July 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

The role of ST2 and ST2 genetic variants in schistosomiasis.

J Allergy Clin Immunol 2017 Nov 9;140(5):1416-1422.e6. Epub 2017 Feb 9.

Division of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.12.969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550370PMC
November 2017

Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases.

Nutrients 2017 Oct 25;9(11). Epub 2017 Oct 25.

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

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http://www.mdpi.com/2072-6643/9/11/1165
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http://dx.doi.org/10.3390/nu9111165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707637PMC
October 2017

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation.

Thromb Haemost 2017 06 16;117(6):1083-1092. Epub 2017 Mar 16.

Andrew D. Johnson, Tenure Track Investigator, Population Sciences Branch, National Heart, Lung, and Blood Institute, The Framingham Heart Study, 73 Mt. Wayte Ave. Suite #2, Framingham, MA 01702, USA, Tel.: +1 508 663 4082, E-mail:

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http://dx.doi.org/10.1160/TH16-09-0677DOI Listing
June 2017

Effect of polymorphisms on TGFB1 on allergic asthma and helminth infection in an African admixed population.

Ann Allergy Asthma Immunol 2017 04 9;118(4):483-488.e1. Epub 2017 Mar 9.

Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, Maryland; Department of Medicine, University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.anai.2017.01.028DOI Listing
April 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.3787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326681PMC
March 2017

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a).

Circ Cardiovasc Genet 2016 Oct 20;9(5):408-418. Epub 2016 Sep 20.

From the Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD (X.Y., L.R.Y., D.M.B., R.A.M., L.C.B.); Lipoprotein Metabolism Section, Pulmonary and Vascular Medicine Branch, NHLBI, National Institutes of Health, Bethesda, MD (A.S., C.K., A.T.R.); and Copenhagen University Hospital, Faculty of Health Sciences, University of Copenhagen, Denmark (B.G.N., A.T.-H.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001402DOI Listing
October 2016

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Authors:
Nathalie Chami Ming-Huei Chen Andrew J Slater John D Eicher Evangelos Evangelou Salman M Tajuddin Latisha Love-Gregory Tim Kacprowski Ursula M Schick Akihiro Nomura Ayush Giri Samuel Lessard Jennifer A Brody Claudia Schurmann Nathan Pankratz Lisa R Yanek Ani Manichaikul Raha Pazoki Evelin Mihailov W David Hill Laura M Raffield Amber Burt Traci M Bartz Diane M Becker Lewis C Becker Eric Boerwinkle Jette Bork-Jensen Erwin P Bottinger Michelle L O'Donoghue David R Crosslin Simon de Denus Marie-Pierre Dubé Paul Elliott Gunnar Engström Michele K Evans James S Floyd Myriam Fornage He Gao Andreas Greinacher Vilmundur Gudnason Torben Hansen Tamara B Harris Caroline Hayward Jussi Hernesniemi Heather M Highland Joel N Hirschhorn Albert Hofman Marguerite R Irvin Mika Kähönen Ethan Lange Lenore J Launer Terho Lehtimäki Jin Li David C M Liewald Allan Linneberg Yongmei Liu Yingchang Lu Leo-Pekka Lyytikäinen Reedik Mägi Rasika A Mathias Olle Melander Andres Metspalu Nina Mononen Mike A Nalls Deborah A Nickerson Kjell Nikus Chris J O'Donnell Marju Orho-Melander Oluf Pedersen Astrid Petersmann Linda Polfus Bruce M Psaty Olli T Raitakari Emma Raitoharju Melissa Richard Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Frank Schmidt Albert Vernon Smith John M Starr Kent D Taylor Alexander Teumer Betina H Thuesen Eric S Torstenson Russell P Tracy Ioanna Tzoulaki Neil A Zakai Caterina Vacchi-Suzzi Cornelia M van Duijn Frank J A van Rooij Mary Cushman Ian J Deary Digna R Velez Edwards Anne-Claire Vergnaud Lars Wallentin Dawn M Waterworth Harvey D White James G Wilson Alan B Zonderman Sekar Kathiresan Niels Grarup Tõnu Esko Ruth J F Loos Leslie A Lange Nauder Faraday Nada A Abumrad Todd L Edwards Santhi K Ganesh Paul L Auer Andrew D Johnson Alexander P Reiner Guillaume Lettre

Am J Hum Genet 2016 Jul 23;99(1):8-21. Epub 2016 Jun 23.

Department of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada; Montreal Heart Institute, Montréal, QC H1T 1C8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005438PMC
July 2016

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Authors:
John D Eicher Nathalie Chami Tim Kacprowski Akihiro Nomura Ming-Huei Chen Lisa R Yanek Salman M Tajuddin Ursula M Schick Andrew J Slater Nathan Pankratz Linda Polfus Claudia Schurmann Ayush Giri Jennifer A Brody Leslie A Lange Ani Manichaikul W David Hill Raha Pazoki Paul Elliot Evangelos Evangelou Ioanna Tzoulaki He Gao Anne-Claire Vergnaud Rasika A Mathias Diane M Becker Lewis C Becker Amber Burt David R Crosslin Leo-Pekka Lyytikäinen Kjell Nikus Jussi Hernesniemi Mika Kähönen Emma Raitoharju Nina Mononen Olli T Raitakari Terho Lehtimäki Mary Cushman Neil A Zakai Deborah A Nickerson Laura M Raffield Rakale Quarells Cristen J Willer Gina M Peloso Goncalo R Abecasis Dajiang J Liu Panos Deloukas Nilesh J Samani Heribert Schunkert Jeanette Erdmann Myriam Fornage Melissa Richard Jean-Claude Tardif John D Rioux Marie-Pierre Dube Simon de Denus Yingchang Lu Erwin P Bottinger Ruth J F Loos Albert Vernon Smith Tamara B Harris Lenore J Launer Vilmundur Gudnason Digna R Velez Edwards Eric S Torstenson Yongmei Liu Russell P Tracy Jerome I Rotter Stephen S Rich Heather M Highland Eric Boerwinkle Jin Li Ethan Lange James G Wilson Evelin Mihailov Reedik Mägi Joel Hirschhorn Andres Metspalu Tõnu Esko Caterina Vacchi-Suzzi Mike A Nalls Alan B Zonderman Michele K Evans Gunnar Engström Marju Orho-Melander Olle Melander Michelle L O'Donoghue Dawn M Waterworth Lars Wallentin Harvey D White James S Floyd Traci M Bartz Kenneth M Rice Bruce M Psaty J M Starr David C M Liewald Caroline Hayward Ian J Deary Andreas Greinacher Uwe Völker Thomas Thiele Henry Völzke Frank J A van Rooij André G Uitterlinden Oscar H Franco Abbas Dehghan Todd L Edwards Santhi K Ganesh Sekar Kathiresan Nauder Faraday Paul L Auer Alex P Reiner Guillaume Lettre Andrew D Johnson

Am J Hum Genet 2016 Jul 23;99(1):40-55. Epub 2016 Jun 23.

Population Sciences Branch, National Heart Lung and Blood Institute, The Framingham Heart Study, Framingham, MA 01702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005441PMC
July 2016

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.

Authors:
Salman M Tajuddin Ursula M Schick John D Eicher Nathalie Chami Ayush Giri Jennifer A Brody W David Hill Tim Kacprowski Jin Li Leo-Pekka Lyytikäinen Ani Manichaikul Evelin Mihailov Michelle L O'Donoghue Nathan Pankratz Raha Pazoki Linda M Polfus Albert Vernon Smith Claudia Schurmann Caterina Vacchi-Suzzi Dawn M Waterworth Evangelos Evangelou Lisa R Yanek Amber Burt Ming-Huei Chen Frank J A van Rooij James S Floyd Andreas Greinacher Tamara B Harris Heather M Highland Leslie A Lange Yongmei Liu Reedik Mägi Mike A Nalls Rasika A Mathias Deborah A Nickerson Kjell Nikus John M Starr Jean-Claude Tardif Ioanna Tzoulaki Digna R Velez Edwards Lars Wallentin Traci M Bartz Lewis C Becker Joshua C Denny Laura M Raffield John D Rioux Nele Friedrich Myriam Fornage He Gao Joel N Hirschhorn David C M Liewald Stephen S Rich Andre Uitterlinden Lisa Bastarache Diane M Becker Eric Boerwinkle Simon de Denus Erwin P Bottinger Caroline Hayward Albert Hofman Georg Homuth Ethan Lange Lenore J Launer Terho Lehtimäki Yingchang Lu Andres Metspalu Chris J O'Donnell Rakale C Quarells Melissa Richard Eric S Torstenson Kent D Taylor Anne-Claire Vergnaud Alan B Zonderman David R Crosslin Ian J Deary Marcus Dörr Paul Elliott Michele K Evans Vilmundur Gudnason Mika Kähönen Bruce M Psaty Jerome I Rotter Andrew J Slater Abbas Dehghan Harvey D White Santhi K Ganesh Ruth J F Loos Tõnu Esko Nauder Faraday James G Wilson Mary Cushman Andrew D Johnson Todd L Edwards Neil A Zakai Guillaume Lettre Alex P Reiner Paul L Auer

Am J Hum Genet 2016 Jul 23;99(1):22-39. Epub 2016 Jun 23.

Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005433PMC
July 2016

Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans.

Br J Nutr 2016 Jan 30;115(2):251-61. Epub 2015 Nov 30.

1Center for Botanical Lipids and Inflammatory Disease Prevention,Wake Forest School of Medicine,Medical Center Blvd,Winston-Salem,NC 27157,USA.

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http://dx.doi.org/10.1017/S0007114515004341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697295PMC
January 2016

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

PLoS One 2014 1;9(7):e100776. Epub 2014 Jul 1.

Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America; Department of Health Care Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, New York, United States of America.

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http://repub.eur.nl/pub/55346/journal.pone.0100776.pdf
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http://dx.plos.org/10.1371/journal.pone.0100776
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077649PMC
November 2015

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.

Blood 2015 Sep 23;126(11):e19-29. Epub 2015 Jun 23.

Department of Epidemiology, and Group Health Research Institute, Group Health Cooperative, Seattle, WA; Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development, Seattle, WA.

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http://dx.doi.org/10.1182/blood-2015-02-624551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566813PMC
September 2015

Directional dominance on stature and cognition in diverse human populations.

Authors:
Peter K Joshi Tonu Esko Hannele Mattsson Niina Eklund Ilaria Gandin Teresa Nutile Anne U Jackson Claudia Schurmann Albert V Smith Weihua Zhang Yukinori Okada Alena Stančáková Jessica D Faul Wei Zhao Traci M Bartz Maria Pina Concas Nora Franceschini Stefan Enroth Veronique Vitart Stella Trompet Xiuqing Guo Daniel I Chasman Jeffery R O'Connel Tanguy Corre Suraj S Nongmaithem Yuning Chen Massimo Mangino Daniela Ruggiero Michela Traglia Aliki-Eleni Farmaki Tim Kacprowski Andrew Bjonnes Ashley van der Spek Ying Wu Anil K Giri Lisa R Yanek Lihua Wang Edith Hofer Cornelius A Rietveld Olga McLeod Marilyn C Cornelis Cristian Pattaro Niek Verweij Clemens Baumbach Abdel Abdellaoui Helen R Warren Dragana Vuckovic Hao Mei Claude Bouchard John R B Perry Stefania Cappellani Saira S Mirza Miles C Benton Ulrich Broeckel Sarah E Medland Penelope A Lind Giovanni Malerba Alexander Drong Loic Yengo Lawrence F Bielak Degui Zhi Peter J van der Most Daniel Shriner Reedik Mägi Gibran Hemani Tugce Karaderi Zhaoming Wang Tian Liu Ilja Demuth Jing Hua Zhao Weihua Meng Lazaros Lataniotis Sander W van der Laan Jonathan P Bradfield Andrew R Wood Amelie Bonnefond Tarunveer S Ahluwalia Leanne M Hall Erika Salvi Seyhan Yazar Lisbeth Carstensen Hugoline G de Haan Mark Abney Uzma Afzal Matthew A Allison Najaf Amin Folkert W Asselbergs Stephan J L Bakker R Graham Barr Sebastian E Baumeister Daniel J Benjamin Sven Bergmann Eric Boerwinkle Erwin P Bottinger Archie Campbell Aravinda Chakravarti Yingleong Chan Stephen J Chanock Constance Chen Y-D Ida Chen Francis S Collins John Connell Adolfo Correa L Adrienne Cupples George Davey Smith Gail Davies Marcus Dörr Georg Ehret Stephen B Ellis Bjarke Feenstra Mary F Feitosa Ian Ford Caroline S Fox Timothy M Frayling Nele Friedrich Frank Geller Generation Scotland Irina Gillham-Nasenya Omri Gottesman Misa Graff Francine Grodstein Charles Gu Chris Haley Christopher J Hammond Sarah E Harris Tamara B Harris Nicholas D Hastie Nancy L Heard-Costa Kauko Heikkilä Lynne J Hocking Georg Homuth Jouke-Jan Hottenga Jinyan Huang Jennifer E Huffman Pirro G Hysi M Arfan Ikram Erik Ingelsson Anni Joensuu Åsa Johansson Pekka Jousilahti J Wouter Jukema Mika Kähönen Yoichiro Kamatani Stavroula Kanoni Shona M Kerr Nazir M Khan Philipp Koellinger Heikki A Koistinen Manraj K Kooner Michiaki Kubo Johanna Kuusisto Jari Lahti Lenore J Launer Rodney A Lea Benjamin Lehne Terho Lehtimäki David C M Liewald Lars Lind Marie Loh Marja-Liisa Lokki Stephanie J London Stephanie J Loomis Anu Loukola Yingchang Lu Thomas Lumley Annamari Lundqvist Satu Männistö Pedro Marques-Vidal Corrado Masciullo Angela Matchan Rasika A Mathias Koichi Matsuda James B Meigs Christa Meisinger Thomas Meitinger Cristina Menni Frank D Mentch Evelin Mihailov Lili Milani May E Montasser Grant W Montgomery Alanna Morrison Richard H Myers Rajiv Nadukuru Pau Navarro Mari Nelis Markku S Nieminen Ilja M Nolte George T O'Connor Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas James S Pankow Inga Patarcic Francesca Pavani Patricia A Peyser Kirsi Pietilainen Neil Poulter Inga Prokopenko Sarju Ralhan Paul Redmond Stephen S Rich Harri Rissanen Antonietta Robino Lynda M Rose Richard Rose Cinzia Sala Babatunde Salako Veikko Salomaa Antti-Pekka Sarin Richa Saxena Helena Schmidt Laura J Scott William R Scott Bengt Sennblad Sudha Seshadri Peter Sever Smeeta Shrestha Blair H Smith Jennifer A Smith Nicole Soranzo Nona Sotoodehnia Lorraine Southam Alice V Stanton Maria G Stathopoulou Konstantin Strauch Rona J Strawbridge Matthew J Suderman Nikhil Tandon Sian-Tsun Tang Kent D Taylor Bamidele O Tayo Anna Maria Töglhofer Maciej Tomaszewski Natalia Tšernikova Jaakko Tuomilehto Andre G Uitterlinden Dhananjay Vaidya Astrid van Hylckama Vlieg Jessica van Setten Tuula Vasankari Sailaja Vedantam Efthymia Vlachopoulou Diego Vozzi Eero Vuoksimaa Melanie Waldenberger Erin B Ware William Wentworth-Shields John B Whitfield Sarah Wild Gonneke Willemsen Chittaranjan S Yajnik Jie Yao Gianluigi Zaza Xiaofeng Zhu The BioBank Japan Project Rany M Salem Mads Melbye Hans Bisgaard Nilesh J Samani Daniele Cusi David A Mackey Richard S Cooper Philippe Froguel Gerard Pasterkamp Struan F A Grant Hakon Hakonarson Luigi Ferrucci Robert A Scott Andrew D Morris Colin N A Palmer George Dedoussis Panos Deloukas Lars Bertram Ulman Lindenberger Sonja I Berndt Cecilia M Lindgren Nicholas J Timpson Anke Tönjes Patricia B Munroe Thorkild I A Sørensen Charles N Rotimi Donna K Arnett Albertine J Oldehinkel Sharon L R Kardia Beverley Balkau Giovanni Gambaro Andrew P Morris Johan G Eriksson Margie J Wright Nicholas G Martin Steven C Hunt John M Starr Ian J Deary Lyn R Griffiths Henning Tiemeier Nicola Pirastu Jaakko Kaprio Nicholas J Wareham Louis Pérusse James G Wilson Giorgia Girotto Mark J Caulfield Olli Raitakari Dorret I Boomsma Christian Gieger Pim van der Harst Andrew A Hicks Peter Kraft Juha Sinisalo Paul Knekt Magnus Johannesson Patrik K E Magnusson Anders Hamsten Reinhold Schmidt Ingrid B Borecki Erkki Vartiainen Diane M Becker Dwaipayan Bharadwaj Karen L Mohlke Michael Boehnke Cornelia M van Duijn Dharambir K Sanghera Alexander Teumer Eleftheria Zeggini Andres Metspalu Paolo Gasparini Sheila Ulivi Carole Ober Daniela Toniolo Igor Rudan David J Porteous Marina Ciullo Tim D Spector Caroline Hayward Josée Dupuis Ruth J F Loos Alan F Wright Giriraj R Chandak Peter Vollenweider Alan Shuldiner Paul M Ridker Jerome I Rotter Naveed Sattar Ulf Gyllensten Kari E North Mario Pirastu Bruce M Psaty David R Weir Markku Laakso Vilmundur Gudnason Atsushi Takahashi John C Chambers Jaspal S Kooner David P Strachan Harry Campbell Joel N Hirschhorn Markus Perola Ozren Polašek James F Wilson

Nature 2015 Jul 1;523(7561):459-462. Epub 2015 Jul 1.

Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.

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July 2015

Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

PLoS Genet 2015 Jun 5;11(6):e1005273. Epub 2015 Jun 5.

Department of Pediatrics, University of Washington, Seattle, Washington, United States of America; Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America; Division of Genetic Medicine, Seattle Children's Hospital, Seattle, Washington, United States of America.

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June 2015

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Authors:
Jennifer Wessel Audrey Y Chu Sara M Willems Shuai Wang Hanieh Yaghootkar Jennifer A Brody Marco Dauriz Marie-France Hivert Sridharan Raghavan Leonard Lipovich Bertha Hidalgo Keolu Fox Jennifer E Huffman Ping An Yingchang Lu Laura J Rasmussen-Torvik Niels Grarup Margaret G Ehm Li Li Abigail S Baldridge Alena Stančáková Ravinder Abrol Céline Besse Anne Boland Jette Bork-Jensen Myriam Fornage Daniel F Freitag Melissa E Garcia Xiuqing Guo Kazuo Hara Aaron Isaacs Johanna Jakobsdottir Leslie A Lange Jill C Layton Man Li Jing Hua Zhao Karina Meidtner Alanna C Morrison Mike A Nalls Marjolein J Peters Maria Sabater-Lleal Claudia Schurmann Angela Silveira Albert V Smith Lorraine Southam Marcus H Stoiber Rona J Strawbridge Kent D Taylor Tibor V Varga Kristine H Allin Najaf Amin Jennifer L Aponte Tin Aung Caterina Barbieri Nathan A Bihlmeyer Michael Boehnke Cristina Bombieri Donald W Bowden Sean M Burns Yuning Chen Yii-DerI Chen Ching-Yu Cheng Adolfo Correa Jacek Czajkowski Abbas Dehghan Georg B Ehret Gudny Eiriksdottir Stefan A Escher Aliki-Eleni Farmaki Mattias Frånberg Giovanni Gambaro Franco Giulianini William A Goddard Anuj Goel Omri Gottesman Megan L Grove Stefan Gustafsson Yang Hai Göran Hallmans Jiyoung Heo Per Hoffmann Mohammad K Ikram Richard A Jensen Marit E Jørgensen Torben Jørgensen Maria Karaleftheri Chiea C Khor Andrea Kirkpatrick Aldi T Kraja Johanna Kuusisto Ethan M Lange I T Lee Wen-Jane Lee Aaron Leong Jiemin Liao Chunyu Liu Yongmei Liu Cecilia M Lindgren Allan Linneberg Giovanni Malerba Vasiliki Mamakou Eirini Marouli Nisa M Maruthur Angela Matchan Roberta McKean-Cowdin Olga McLeod Ginger A Metcalf Karen L Mohlke Donna M Muzny Ioanna Ntalla Nicholette D Palmer Dorota Pasko Andreas Peter Nigel W Rayner Frida Renström Ken Rice Cinzia F Sala Bengt Sennblad Ioannis Serafetinidis Jennifer A Smith Nicole Soranzo Elizabeth K Speliotes Eli A Stahl Kathleen Stirrups Nikos Tentolouris Anastasia Thanopoulou Mina Torres Michela Traglia Emmanouil Tsafantakis Sundas Javad Lisa R Yanek Eleni Zengini Diane M Becker Joshua C Bis James B Brown L Adrienne Cupples Torben Hansen Erik Ingelsson Andrew J Karter Carlos Lorenzo Rasika A Mathias Jill M Norris Gina M Peloso Wayne H-H Sheu Daniela Toniolo Dhananjay Vaidya Rohit Varma Lynne E Wagenknecht Heiner Boeing Erwin P Bottinger George Dedoussis Panos Deloukas Ele Ferrannini Oscar H Franco Paul W Franks Richard A Gibbs Vilmundur Gudnason Anders Hamsten Tamara B Harris Andrew T Hattersley Caroline Hayward Albert Hofman Jan-Håkan Jansson Claudia Langenberg Lenore J Launer Daniel Levy Ben A Oostra Christopher J O'Donnell Stephen O'Rahilly Sandosh Padmanabhan James S Pankow Ozren Polasek Michael A Province Stephen S Rich Paul M Ridker Igor Rudan Matthias B Schulze Blair H Smith André G Uitterlinden Mark Walker Hugh Watkins Tien Y Wong Eleftheria Zeggini Markku Laakso Ingrid B Borecki Daniel I Chasman Oluf Pedersen Bruce M Psaty E Shyong Tai Cornelia M van Duijn Nicholas J Wareham Dawn M Waterworth Eric Boerwinkle W H Linda Kao Jose C Florez Ruth J F Loos James G Wilson Timothy M Frayling David S Siscovick Josée Dupuis Jerome I Rotter James B Meigs Robert A Scott Mark O Goodarzi

Nat Commun 2015 Jan 29;6:5897. Epub 2015 Jan 29.

1] Department of Medicine and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA [2] Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311266PMC
January 2015

DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.

PLoS One 2014 19;9(5):e97510. Epub 2014 May 19.

Department of Physiology/Pharmacology, Wake Forest Health Sciences, Winston-Salem, North Carolina, United States of America; Wake Forest Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026313PMC
December 2014

Admixture mapping identifies a quantitative trait locus associated with FEV1/FVC in the COPDGene Study.

Genet Epidemiol 2014 Nov 11;38(7):652-9. Epub 2014 Aug 11.

Department of Epidemiology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1002/gepi.21847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190160PMC
November 2014

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.

J Biol Chem 2014 Aug 24;289(32):22482-9. Epub 2014 Jun 24.

the Department of Physiology/Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Molecular Medicine and Translation Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157

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http://dx.doi.org/10.1074/jbc.M114.579557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139254PMC
August 2014

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.

PLoS Genet 2014 Aug 7;10(8):e1004517. Epub 2014 Aug 7.

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125087PMC
August 2014

Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake.

Curr Nutr Rep 2014 Jun;3(2):139-148

The Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest School of Medicine, Winston-Salem NC, 27157, USA ; Department of Physiology/Pharmacology, Wake Forest School of Medicine, Winston-Salem NC 27157, USA ; Molecular Medicine and Translational Sciences, Wake Forest School of Medicine, Winston-Salem NC 27157, USA.

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http://dx.doi.org/10.1007/s13668-014-0079-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070521PMC
June 2014

Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases.

Nutrients 2014 May 21;6(5):1993-2022. Epub 2014 May 21.

Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.3390/nu6051993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042578PMC
May 2014

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms.

Br J Med Med Res 2014 Mar;4(6):1413-1422

Johns Hopkins School of Medicine, Department of Medicine, Baltimore, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969754PMC
March 2014

On the threshold from genome-wide association studies to whole-genome sequencing. Looking for signal in all the right places.

Am J Respir Crit Care Med 2014 Feb;189(4):381-3

1 Johns Hopkins School of Medicine Baltimore, Maryland.

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February 2014

Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation.

PLoS One 2013 21;8(5):e64179. Epub 2013 May 21.

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660448PMC
December 2013

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.

Authors:
Sarah H Stephens Sarah M Hartz Nicole R Hoft Nancy L Saccone Robin C Corley John K Hewitt Christian J Hopfer Naomi Breslau Hilary Coon Xiangning Chen Francesca Ducci Nicole Dueker Nora Franceschini Josef Frank Younghun Han Nadia N Hansel Chenhui Jiang Tellervo Korhonen Penelope A Lind Jason Liu Leo-Pekka Lyytikäinen Martha Michel John R Shaffer Susan E Short Juzhong Sun Alexander Teumer John R Thompson Nicole Vogelzangs Jacqueline M Vink Angela Wenzlaff William Wheeler Bao-Zhu Yang Steven H Aggen Anthony J Balmforth Sebastian E Baumeister Terri H Beaty Daniel J Benjamin Andrew W Bergen Ulla Broms David Cesarini Nilanjan Chatterjee Jingchun Chen Yu-Ching Cheng Sven Cichon David Couper Francesco Cucca Danielle Dick Tatiana Foroud Helena Furberg Ina Giegling Nathan A Gillespie Fangyi Gu Alistair S Hall Jenni Hällfors Shizhong Han Annette M Hartmann Kauko Heikkilä Ian B Hickie Jouke Jan Hottenga Pekka Jousilahti Marika Kaakinen Mika Kähönen Philipp D Koellinger Stephen Kittner Bettina Konte Maria-Teresa Landi Tiina Laatikainen Mark Leppert Steven M Levy Rasika A Mathias Daniel W McNeil Sarah E Medland Grant W Montgomery Tanda Murray Matthias Nauck Kari E North Peter D Paré Michele Pergadia Ingo Ruczinski Veikko Salomaa Jorma Viikari Gonneke Willemsen Kathleen C Barnes Eric Boerwinkle Dorret I Boomsma Neil Caporaso Howard J Edenberg Clyde Francks Joel Gelernter Hans Jörgen Grabe Hyman Hops Marjo-Riitta Jarvelin Magnus Johannesson Kenneth S Kendler Terho Lehtimäki Patrik K E Magnusson Mary L Marazita Jonathan Marchini Braxton D Mitchell Markus M Nöthen Brenda W Penninx Olli Raitakari Marcella Rietschel Dan Rujescu Nilesh J Samani Ann G Schwartz Sanjay Shete Margaret Spitz Gary E Swan Henry Völzke Juha Veijola Qingyi Wei Chris Amos Dale S Cannon Richard Grucza Dorothy Hatsukami Andrew Heath Eric O Johnson Jaakko Kaprio Pamela Madden Nicholas G Martin Victoria L Stevens Robert B Weiss Peter Kraft Laura J Bierut Marissa A Ehringer

Genet Epidemiol 2013 Dec 1;37(8):846-59. Epub 2013 Nov 1.

Department of Epidemiology and Public Health, University of Maryland, Baltimore, Maryland, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947535PMC
December 2013

The robustness of generalized estimating equations for association tests in extended family data.

Hum Hered 2012 3;74(1):17-26. Epub 2012 Oct 3.

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736986PMC
April 2013

Adaptive evolution of the FADS gene cluster within Africa.

PLoS One 2012 19;7(9):e44926. Epub 2012 Sep 19.

Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446990PMC
March 2013

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Authors:
Sarah M Hartz Susan E Short Nancy L Saccone Robert Culverhouse LiShiun Chen Tae-Hwi Schwantes-An Hilary Coon Younghun Han Sarah H Stephens Juzhong Sun Xiangning Chen Francesca Ducci Nicole Dueker Nora Franceschini Josef Frank Frank Geller Daniel Gubjartsson Nadia N Hansel Chenhui Jiang Kaisu Keskitalo-Vuokko Zhen Liu Leo-Pekka Lyytikäinen Martha Michel Rajesh Rawal Albert Rosenberger Paul Scheet John R Shaffer Alexander Teumer John R Thompson Jacqueline M Vink Nicole Vogelzangs Angela S Wenzlaff William Wheeler Xiangjun Xiao Bao-Zhu Yang Steven H Aggen Anthony J Balmforth Sebastian E Baumeister Terri Beaty Siiri Bennett Andrew W Bergen Heather A Boyd Ulla Broms Harry Campbell Nilanjan Chatterjee Jingchun Chen Yu-Ching Cheng Sven Cichon David Couper Francesco Cucca Danielle M Dick Tatiana Foroud Helena Furberg Ina Giegling Fangyi Gu Alistair S Hall Jenni Hällfors Shizhong Han Annette M Hartmann Caroline Hayward Kauko Heikkilä John K Hewitt Jouke Jan Hottenga Majken K Jensen Pekka Jousilahti Marika Kaakinen Steven J Kittner Bettina Konte Tellervo Korhonen Maria-Teresa Landi Tiina Laatikainen Mark Leppert Steven M Levy Rasika A Mathias Daniel W McNeil Sarah E Medland Grant W Montgomery Thomas Muley Tanda Murray Matthias Nauck Kari North Michele Pergadia Ozren Polasek Erin M Ramos Samuli Ripatti Angela Risch Ingo Ruczinski Igor Rudan Veikko Salomaa David Schlessinger Unnur Styrkársdóttir Antonio Terracciano Manuela Uda Gonneke Willemsen Xifeng Wu Goncalo Abecasis Kathleen Barnes Heike Bickeböller Eric Boerwinkle Dorret I Boomsma Neil Caporaso Jubao Duan Howard J Edenberg Clyde Francks Pablo V Gejman Joel Gelernter Hans Jörgen Grabe Hyman Hops Marjo-Riitta Jarvelin Jorma Viikari Mika Kähönen Kenneth S Kendler Terho Lehtimäki Douglas F Levinson Mary L Marazita Jonathan Marchini Mads Melbye Braxton D Mitchell Jeffrey C Murray Markus M Nöthen Brenda W Penninx Olli Raitakari Marcella Rietschel Dan Rujescu Nilesh J Samani Alan R Sanders Ann G Schwartz Sanjay Shete Jianxin Shi Margaret Spitz Kari Stefansson Gary E Swan Thorgeir Thorgeirsson Henry Völzke Qingyi Wei H-Erich Wichmann Christopher I Amos Naomi Breslau Dale S Cannon Marissa Ehringer Richard Grucza Dorothy Hatsukami Andrew Heath Eric O Johnson Jaakko Kaprio Pamela Madden Nicholas G Martin Victoria L Stevens Jerry A Stitzel Robert B Weiss Peter Kraft Laura J Bierut

Arch Gen Psychiatry 2012 Aug;69(8):854-60

Washington University School of Medicine, St Louis, Missouri, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482121PMC
August 2012

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.

PLoS Genet 2011 Oct 6;7(10):e1002298. Epub 2011 Oct 6.

Montreal Heart Institute, Montréal, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188544PMC
October 2011

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

Nat Genet 2011 Jul 31;43(9):887-92. Epub 2011 Jul 31.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ng.888DOI Listing
July 2011

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.

Authors:
Themistocles L Assimes Hilma Hólm Sekar Kathiresan Muredach P Reilly Gudmar Thorleifsson Benjamin F Voight Jeanette Erdmann Christina Willenborg Dhananjay Vaidya Changchun Xie Chris C Patterson Thomas M Morgan Mary Susan Burnett Mingyao Li Mark A Hlatky Joshua W Knowles John R Thompson Devin Absher Carlos Iribarren Alan Go Stephen P Fortmann Stephen Sidney Neil Risch Hua Tang Richard M Myers Klaus Berger Monika Stoll Svati H Shah Gudmundur Thorgeirsson Karl Andersen Aki S Havulinna J Enrique Herrera Nauder Faraday Yoonhee Kim Brian G Kral Rasika A Mathias Ingo Ruczinski Bhoom Suktitipat Alexander F Wilson Lisa R Yanek Lewis C Becker Patrick Linsel-Nitschke Wolfgang Lieb Inke R König Christian Hengstenberg Marcus Fischer Klaus Stark Wibke Reinhard Janina Winogradow Martina Grassl Anika Grosshennig Michael Preuss Stefan Schreiber H-Erich Wichmann Christa Meisinger Jean Yee Yechiel Friedlander Ron Do James B Meigs Gordon Williams David M Nathan Calum A MacRae Liming Qu Robert L Wilensky William H Matthai Atif N Qasim Hakon Hakonarson Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Christopher W Knouff Dawn M Waterworth Max C Walker Vincent E Mooser Jaume Marrugat Gavin Lucas Isaac Subirana Joan Sala Rafael Ramos Nicola Martinelli Oliviero Olivieri Elisabetta Trabetti Giovanni Malerba Pier Franco Pignatti Candace Guiducci Daniel Mirel Melissa Parkin Joel N Hirschhorn Rosanna Asselta Stefano Duga Kiran Musunuru Mark J Daly Shaun Purcell Sandra Eifert Peter S Braund Benjamin J Wright Anthony J Balmforth Stephen G Ball Willem H Ouwehand Panos Deloukas Michael Scholz Francois Cambien Andreas Huge Thomas Scheffold Veikko Salomaa Domenico Girelli Christopher B Granger Leena Peltonen Pascal P McKeown David Altshuler Olle Melander Joseph M Devaney Stephen E Epstein Daniel J Rader Roberto Elosua James C Engert Sonia S Anand Alistair S Hall Andreas Ziegler Christopher J O'Donnell John A Spertus David Siscovick Stephen M Schwartz Diane Becker Unnur Thorsteinsdottir Kari Stefansson Heribert Schunkert Nilesh J Samani Thomas Quertermous

J Am Coll Cardiol 2010 Nov;56(19):1552-63

Department of Medicine, Stanford University School of Medicine, Stanford, California 94304-1334, USA.

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http://dx.doi.org/10.1016/j.jacc.2010.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084526PMC
November 2010

Independent metabolic syndrome variants predict new-onset coronary artery disease.

Diabetes Care 2010 Jun 18;33(6):1376-8. Epub 2010 Mar 18.

Department of Medicine, Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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http://dx.doi.org/10.2337/dc09-2211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875458PMC
June 2010

Evaluation of random forests performance for genome-wide association studies in the presence of interaction effects.

BMC Proc 2009 Dec 15;3 Suppl 7:S64. Epub 2009 Dec 15.

National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795965PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s64DOI Listing
December 2009

Heritability of quantitative traits associated with type 2 diabetes mellitus in large multiplex families from South India.

Metabolism 2009 Oct 1;58(10):1439-45. Epub 2009 Jul 1.

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.metabol.2009.04.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408214PMC
October 2009

Segregation analysis of restless legs syndrome: possible evidence for a major gene in a family study using blinded diagnoses.

Hum Hered 2006 24;62(3):157-64. Epub 2006 Oct 24.

Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD, USA.

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February 2007