Publications by authors named "Raquel Granell"

63Publications

The effect of catch-up growth in the first year of life on later wheezing phenotypes.

Eur Respir J 2020 Jun 25. Epub 2020 Jun 25.

Department of Child Health, Cardiff University School of Medicine, Cardiff, UK

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http://dx.doi.org/10.1183/13993003.00884-2020DOI Listing
June 2020

Residential greenspace and lung function up to 24 years of age: The ALSPAC birth cohort.

Environ Int 2020 Jul 4;140:105749. Epub 2020 May 4.

National Heart and Lung Institute, Imperial College London, London, United Kingdom; MRC-PHE Centre for Environment & Health, Imperial College, London, United Kingdom.

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http://dx.doi.org/10.1016/j.envint.2020.105749DOI Listing
July 2020

Prenatal, Early-Life, and Childhood Exposure to Air Pollution and Lung Function: The ALSPAC Cohort.

Am J Respir Crit Care Med 2020 07;202(1):112-123

MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, and.

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http://dx.doi.org/10.1164/rccm.201902-0286OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328307PMC
July 2020

Confirmed causal effect of obesity on asthma and new insights on potential underlying shared genetic mechanisms.

J Allergy Clin Immunol 2020 02 6;145(2):484-486. Epub 2019 Dec 6.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2019.11.033DOI Listing
February 2020

Differential associations of allergic disease genetic variants with developmental profiles of eczema, wheeze and rhinitis.

Clin Exp Allergy 2019 11 15;49(11):1475-1486. Epub 2019 Oct 15.

MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1111/cea.13485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899469PMC
November 2019

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

Am J Hum Genet 2019 04 28;104(4):665-684. Epub 2019 Mar 28.

Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm 171 77, Sweden; Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm 171 76, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297193006
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http://dx.doi.org/10.1016/j.ajhg.2019.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451732PMC
April 2019

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation.

BMC Genet 2018 12 14;19(1):113. Epub 2018 Dec 14.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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https://bmcgenet.biomedcentral.com/articles/10.1186/s12863-0
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http://dx.doi.org/10.1186/s12863-018-0703-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295101PMC
December 2018

Causes of variability in latent phenotypes of childhood wheeze.

J Allergy Clin Immunol 2019 05 5;143(5):1783-1790.e11. Epub 2018 Dec 5.

Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183172
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http://dx.doi.org/10.1016/j.jaci.2018.10.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505513PMC
May 2019

The Simple 10-Item Predicting Asthma Risk in Children Tool to Predict Childhood Asthma-An External Validation.

J Allergy Clin Immunol Pract 2019 03 9;7(3):943-953.e4. Epub 2018 Oct 9.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183060
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http://dx.doi.org/10.1016/j.jaip.2018.09.032DOI Listing
March 2019

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0197-6DOI Listing
September 2018

Respiratory Phenotypes during Childhood and Early-Life Exposures.

Authors:
Raquel Granell

Am J Respir Crit Care Med 2019 01;199(1):7-9

1 Bristol Medical School University of Bristol Bristol, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201807-1359EDDOI Listing
January 2019

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0157-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068780PMC
August 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Temporal stability of multitrigger and episodic viral wheeze in early childhood.

Eur Respir J 2017 11 2;50(5). Epub 2017 Nov 2.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1183/13993003.00014-2017DOI Listing
November 2017

Sex discordance in asthma and wheeze prevalence in two longitudinal cohorts.

PLoS One 2017 25;12(4):e0176293. Epub 2017 Apr 25.

School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176293PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404857PMC
September 2017

TRPA1 gene polymorphisms and childhood asthma.

Pediatr Allergy Immunol 2017 03 8;28(2):191-198. Epub 2016 Dec 8.

Centre for Primary Care and Public Health, Barts and The London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1111/pai.12673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324656PMC
March 2017

Associations of wheezing phenotypes with late asthma outcomes in the Avon Longitudinal Study of Parents and Children: A population-based birth cohort.

J Allergy Clin Immunol 2016 10 20;138(4):1060-1070.e11. Epub 2016 Apr 20.

School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2016.01.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052126PMC
October 2016

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.

Nat Commun 2015 Dec 4;6:8658. Epub 2015 Dec 4.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ncomms9658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686825PMC
December 2015

Influence of childhood growth on asthma and lung function in adolescence.

J Allergy Clin Immunol 2015 Jun 8;135(6):1435-43.e7. Epub 2015 Jan 8.

School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.10.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452091PMC
June 2015

Developmental profiles of eczema, wheeze, and rhinitis: two population-based birth cohort studies.

PLoS Med 2014 Oct 21;11(10):e1001748. Epub 2014 Oct 21.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, United Kingdom.

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http://research.microsoft.com/en-us/um/people/cmbishop/downl
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http://dx.plos.org/10.1371/journal.pmed.1001748
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http://dx.doi.org/10.1371/journal.pmed.1001748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204810PMC
October 2014

Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study.

PLoS Med 2014 Jul 1;11(7):e1001669. Epub 2014 Jul 1.

School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077660PMC
July 2014

Validating childhood asthma in an epidemiological study using linked electronic patient records.

BMJ Open 2014 Apr 23;4(4):e005345. Epub 2014 Apr 23.

School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjopen-2014-005345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010849PMC
April 2014

Association of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood.

J Allergy Clin Immunol 2014 Jul 22;134(1):170-7. Epub 2014 Feb 22.

University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC Research Institute, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.12.1080DOI Listing
July 2014

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.

J Allergy Clin Immunol 2014 Mar 6;133(3):885-8. Epub 2013 Dec 6.

Department of Epidemiology, University of Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.08.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969577PMC
March 2014

Transient early wheeze and lung function in early childhood associated with chronic obstructive pulmonary disease genes.

J Allergy Clin Immunol 2014 Jan 22;133(1):68-76.e1-4. Epub 2013 Jul 22.

Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2013.06.004DOI Listing
January 2014

Prospective association of 25-hydroxyvitamin d3 and d2 with childhood lung function, asthma, wheezing, and flexural dermatitis.

Epidemiology 2013 Mar;24(2):310-9

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1097/EDE.obo13e318280dd5eDOI Listing
March 2013

Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort.

J Allergy Clin Immunol 2012 Aug;130(2):503-9.e7

School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2012.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871225PMC
August 2012

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Authors:
María Soler Artigas Daan W Loth Louise V Wain Sina A Gharib Ma'en Obeidat Wenbo Tang Guangju Zhai Jing Hua Zhao Albert Vernon Smith Jennifer E Huffman Eva Albrecht Catherine M Jackson David M Evans Gemma Cadby Myriam Fornage Ani Manichaikul Lorna M Lopez Toby Johnson Melinda C Aldrich Thor Aspelund Inês Barroso Harry Campbell Patricia A Cassano David J Couper Gudny Eiriksdottir Nora Franceschini Melissa Garcia Christian Gieger Gauti Kjartan Gislason Ivica Grkovic Christopher J Hammond Dana B Hancock Tamara B Harris Adaikalavan Ramasamy Susan R Heckbert Markku Heliövaara Georg Homuth Pirro G Hysi Alan L James Stipan Jankovic Bonnie R Joubert Stefan Karrasch Norman Klopp Beate Koch Stephen B Kritchevsky Lenore J Launer Yongmei Liu Laura R Loehr Kurt Lohman Ruth J F Loos Thomas Lumley Khalid A Al Balushi Wei Q Ang R Graham Barr John Beilby John D Blakey Mladen Boban Vesna Boraska Jonas Brisman John R Britton Guy G Brusselle Cyrus Cooper Ivan Curjuric Santosh Dahgam Ian J Deary Shah Ebrahim Mark Eijgelsheim Clyde Francks Darya Gaysina Raquel Granell Xiangjun Gu John L Hankinson Rebecca Hardy Sarah E Harris John Henderson Amanda Henry Aroon D Hingorani Albert Hofman Patrick G Holt Jennie Hui Michael L Hunter Medea Imboden Karen A Jameson Shona M Kerr Ivana Kolcic Florian Kronenberg Jason Z Liu Jonathan Marchini Tricia McKeever Andrew D Morris Anna-Carin Olin David J Porteous Dirkje S Postma Stephen S Rich Susan M Ring Fernando Rivadeneira Thierry Rochat Avan Aihie Sayer Ian Sayers Peter D Sly George Davey Smith Akshay Sood John M Starr André G Uitterlinden Judith M Vonk S Goya Wannamethee Peter H Whincup Cisca Wijmenga O Dale Williams Andrew Wong Massimo Mangino Kristin D Marciante Wendy L McArdle Bernd Meibohm Alanna C Morrison Kari E North Ernst Omenaas Lyle J Palmer Kirsi H Pietiläinen Isabelle Pin Ozren Pola Sbreve Ek Anneli Pouta Bruce M Psaty Anna-Liisa Hartikainen Taina Rantanen Samuli Ripatti Jerome I Rotter Igor Rudan Alicja R Rudnicka Holger Schulz So-Youn Shin Tim D Spector Ida Surakka Veronique Vitart Henry Völzke Nicholas J Wareham Nicole M Warrington H-Erich Wichmann Sarah H Wild Jemma B Wilk Matthias Wjst Alan F Wright Lina Zgaga Tatijana Zemunik Craig E Pennell Fredrik Nyberg Diana Kuh John W Holloway H Marike Boezen Debbie A Lawlor Richard W Morris Nicole Probst-Hensch Jaakko Kaprio James F Wilson Caroline Hayward Mika Kähönen Joachim Heinrich Arthur W Musk Deborah L Jarvis Sven Gläser Marjo-Riitta Järvelin Bruno H Ch Stricker Paul Elliott George T O'Connor David P Strachan Stephanie J London Ian P Hall Vilmundur Gudnason Martin D Tobin

Nat Genet 2011 Sep 25;43(11):1082-90. Epub 2011 Sep 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267376PMC
September 2011

Folic acid in pregnancy - is there a link with childhood asthma or wheeze?

Aust Fam Physician 2011 Jun;40(6):421-4

Discipline of General Practice, School of Primary, Aboriginal and Rural Health Care, University of Western Australia, Perth, Australia.

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June 2011

Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses.

Am J Epidemiol 2011 Jun 9;173(12):1392-403. Epub 2011 May 9.

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1093/aje/kwr026DOI Listing
June 2011

Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA.

J Allergy Clin Immunol 2011 Jun 16;127(6):1505-12.e14. Epub 2011 Mar 16.

Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2011.02.002DOI Listing
June 2011

Genome-wide association study identifies five loci associated with lung function.

Nat Genet 2010 Jan 13;42(1):36-44. Epub 2009 Dec 13.

Departments of Health Sciences and Genetics, Adrian Building, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/ng.501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862965PMC
January 2010

Mothers' anxiety during pregnancy is associated with asthma in their children.

J Allergy Clin Immunol 2009 Apr;123(4):847-53.e11

Department of Internal Medicine, Sir Charles Gairdner Hospital, Perth, Australia.

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http://dx.doi.org/10.1016/j.jaci.2009.01.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726292PMC
April 2009