Raquel Almansa

Raquel Almansa

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Raquel Almansa

Raquel Almansa

Publications by authors named "Raquel Almansa"

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Simultaneous Depression of Immunological Synapse and Endothelial Injury is Associated with Organ Dysfunction in Community-Acquired Pneumonia.

J Clin Med 2019 Sep 6;8(9). Epub 2019 Sep 6.

Centro de Investigación Biomédica En Red-Enfermedades Respiratorias (CibeRes, 58 CB06/06/0028), Instituto de salud Carlos III (ISCIII), Av. de Monforte de Lemos, 5, 59 28029 Madrid, Spain.

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https://www.mdpi.com/2077-0383/8/9/1404
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http://dx.doi.org/10.3390/jcm8091404DOI Listing
September 2019

Composed endotypes to guide antibiotic discontinuation in sepsis.

Crit Care 2019 Apr 24;23(1):140. Epub 2019 Apr 24.

Group for Biomedical Research in Sepsis (BioSepsis), Hospital Clínico Universitario de Valladolid/IECSCYL, Av. Ramón y Cajal, 3, 47003, Valladolid, Spain.

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http://dx.doi.org/10.1186/s13054-019-2439-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482544PMC
April 2019

Shared Features of Endothelial Dysfunction between Sepsis and Its Preceding Risk Factors (Aging and Chronic Disease).

J Clin Med 2018 Oct 30;7(11). Epub 2018 Oct 30.

Group for Biomedical Research in Sepsis (Bio∙Sepsis), Hospital Clínico Universitario de Valladolid/IECSCYL, Av. Ramón y Cajal, 3, 47003 Valladolid, Spain.

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http://dx.doi.org/10.3390/jcm7110400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262336PMC
October 2018

Gene expression analysis identify a metabolic and cell function alterations as a hallmark of obesity without metabolic syndrome in peripheral blood, a pilot study.

Clin Nutr 2018 08 10;37(4):1348-1353. Epub 2017 Jun 10.

Center of Investigation of Endocrinology and Nutrition, Medicine School and Dpt. of Endocrinology and Nutrition, University of Valladolid, Valladolid, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S02615614173021
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http://dx.doi.org/10.1016/j.clnu.2017.06.006DOI Listing
August 2018

New Organ Failure as an Alternative Endpoint to Develop Diagnostic Criteria for Sepsis.

Chest 2018 05;153(5):1278

Servei de Medicina Intensiva, Hospital de Mataró, Mataró, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.chest.2017.11.046DOI Listing
May 2018

Pre-sepsis: A necessary concept to complete the SEPSIS-3 picture?

J Crit Care 2018 04 29;44:148. Epub 2017 Oct 29.

Group for Biomedical research in Sepsis (Bio Sepsis), Hospital Clínico Universitario de Valladolid/IECSCYL, Av. Ramón y Cajal, 3, 47003 Valladolid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2017.10.041DOI Listing
April 2018

IL-6 rs1800795 polymorphism is associated with septic shock-related death in patients who underwent major surgery: a preliminary retrospective study.

Ann Intensive Care 2017 Dec 28;7(1):22. Epub 2017 Feb 28.

Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología, Instituto de Salud Carlos III (Campus Majadahonda), Carretera Majadahonda- Pozuelo, Km 2.2, 28220, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1186/s13613-017-0247-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331026PMC
December 2017

Immunological profiling to assess disease severity and prognosis in community-acquired pneumonia.

Lancet Respir Med 2017 12;5(12):e35-e36

Department of Pneumology, Institut Clinic del Tórax, Hospital Clinic of Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona-SGR 911- Ciber de Enfermedades Respiratorias (Ciberes), Barcelona, Spain.

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http://dx.doi.org/10.1016/S2213-2600(17)30444-7DOI Listing
December 2017

Lymphopenic Community Acquired Pneumonia (L-CAP), an Immunological Phenotype Associated with Higher Risk of Mortality.

EBioMedicine 2017 Oct 21;24:231-236. Epub 2017 Sep 21.

Pulmonology Service, University and Polytechnic Hospital La Fe, Ciber de Enfermedades Respiratorias (Ciberes), Avinguda de Fernando Abril Martorell, 106, 46026 València, Spain.

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http://dx.doi.org/10.1016/j.ebiom.2017.09.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652132PMC
October 2017

Pulmonary transcriptomic responses indicate a dual role of inflammation in pneumonia development and viral clearance during 2009 pandemic influenza infection.

PeerJ 2017 11;5:e3915. Epub 2017 Oct 11.

Laboratory of Biomedical Research in Sepsis (BIOSEPSIS), Hospital Clínico Universitario de Valladolid, Instituto de Estudios de Ciencias de la Salud de Castilla y León (IECSCYL), Valladolid, Spain.

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http://dx.doi.org/10.7717/peerj.3915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640978PMC
October 2017

Characterizing Systemic Immune Dysfunction Syndrome to Fill in the Gaps of SEPSIS-2 and SEPSIS-3 Definitions.

Chest 2017 02;151(2):518-519

Grupo de Investigación Clínica en Infección e Inmunidad, Hospital Clínico Universitario/IECSCYL, Valladolid, Spain.

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http://dx.doi.org/10.1016/j.chest.2016.11.047DOI Listing
February 2017

IL-1B rs16944 polymorphism is related to septic shock and death.

Eur J Clin Invest 2017 Jan 7;47(1):53-62. Epub 2016 Dec 7.

Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain.

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http://dx.doi.org/10.1111/eci.12702DOI Listing
January 2017

Defining immunological dysfunction in sepsis: A requisite tool for precision medicine.

J Infect 2016 May 3;72(5):525-36. Epub 2016 Feb 3.

Grupo de Investigación Biomédica en Cuidados Críticos (BioCritic), Hospital Clínico Universitario de Valladolid, Avenida Ramón y Cajal, 3, 47005 Valladolid, Spain; Servicio de Anestesiología y Reanimación, Hospital Clínico Universitario de Valladolid, SACYL, Avenida Ramón y Cajal, 3, 47005 Valladolid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01634453160002
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http://dx.doi.org/10.1016/j.jinf.2016.01.010DOI Listing
May 2016

Preventing sepsis.

Lancet Infect Dis 2015 Nov;15(11):1259-60

Grupo de Investigación Biomédica en Cuidados Críticos (BioCritic), Hospital Clínico Universitario de Valladolid, SACYL & IECSCYL, 47005 Valladolid, Spain; Servicio de Anestesiología y Reanimación, Hospital Clínico Universitario de Valladolid, SACYL, Valladolid, Spain.

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http://dx.doi.org/10.1016/S1473-3099(15)00374-6DOI Listing
November 2015

Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses.

PLoS Pathog 2015 Oct 8;11(10):e1005173. Epub 2015 Oct 8.

Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Immune Diagnostics & Research, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.ppat.1005173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598190PMC
October 2015

Transcriptomic correlates of organ failure extent in sepsis.

J Infect 2015 May 31;70(5):445-56. Epub 2014 Dec 31.

Grupo de Investigación Biomédica en Cuidados Críticos (BioCritic), Hospital Clínico Universitario de Valladolid, SACYL/IECSYL, Avenida Ramón y Cajal, 3, 47005 Valladolid, Spain; Servicio de Anestesiología, Hospital Clínico Universitario de Valladolid, SACYL, Avenida Ramón y Cajal, 3, 47005 Valladolid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2014.12.010DOI Listing
May 2015

Immunoinformatics and systems biology in personalized medicine.

Methods Mol Biol 2014 ;1184:457-75

Health and Biomedical Informatics Centre, The University of Melbourne, Level 1, 202 Berkeley Street, Parkville, VIC, 3010, Australia.

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http://dx.doi.org/10.1007/978-1-4939-1115-8_25DOI Listing
March 2015

The original sins of clinical trials with intravenous immunoglobulins in sepsis.

Crit Care 2015 Feb 26;19:90. Epub 2015 Feb 26.

Group of Biomedical Research in Critical Care Medicine (BioCritic), Hospital Clínico Universitario de Valladolid, Avda. Ramón y Cajal, 3. 47005, Valladolid, Spain.

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http://dx.doi.org/10.1186/s13054-015-0793-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343266PMC
February 2015

Hyperimmune serum from healthy vaccinated individuals for Ebola virus disease?

Lancet Glob Health 2014 Dec 30;2(12):e686. Epub 2014 Oct 30.

Hospital Clínico Universitario de Valladolid, SACYL/IECSYL, 47005 Valladolid, Spain. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(14)70341-9DOI Listing
December 2014

Cytokine profiles linked to fatal outcome in infective prosthetic valve endocarditis.

APMIS 2014 Jun 30;122(6):526-9. Epub 2013 Sep 30.

Department of Cardiovascular Surgery, Hospital Universitario de La Princesa, Madrid, Spain; Grupo de Investigación en Sepsis, Valladolid, Spain.

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http://dx.doi.org/10.1111/apm.12189DOI Listing
June 2014

Transcriptomic evidence of impaired immunoglobulin G production in fatal septic shock.

J Crit Care 2014 Apr 2;29(2):307-9. Epub 2013 Dec 2.

Laboratorio de Ciencias Biomédicas en Investigación Clínica (CBIC), Hospital Clínico Universitario de Valladolid, IECSCYL-SACYL, Valladolid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2013.11.020DOI Listing
April 2014

Eosinophil as a protective cell in S. aureus ventilator-associated pneumonia.

Mediators Inflamm 2013 3;2013:152943. Epub 2013 Sep 3.

Microbiology Service, Clinical University Hospital-SACYL, Avda Ramón y Cajal 3, 47005 Valladolid, Spain.

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http://dx.doi.org/10.1155/2013/152943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776384PMC
February 2014

IgA level in plasma as a differential factor for influenza infection in severe viral pneumonia.

J Clin Virol 2014 Feb 12;59(2):135-6. Epub 2013 Dec 12.

Unidad de Investigación Biomédica, Hospital Clínico Universitario de Valladolid (ibC), SACYL/IECSCYL, Avda Ramón y Cajal 3, 47005 Valladolid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2013.12.003DOI Listing
February 2014

Beneficial role of endogenous immunoglobulin subclasses and isotypes in septic shock.

J Crit Care 2012 Dec 22;27(6):616-22. Epub 2012 Oct 22.

Anesthesiology and Reanimation Service, Hospital Clínico Universitario-SACYL, 47005 Valladolid, Spain.

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http://dx.doi.org/10.1016/j.jcrc.2012.08.004DOI Listing
December 2012

MCP-1 in urine as biomarker of disease activity in Systemic Lupus Erythematosus.

Cytokine 2012 Nov 3;60(2):583-6. Epub 2012 Aug 3.

Autoimmunity Unit, Internal Medicine Service, Hospital Clínico Universitario de Valladolid-SACYL, Ramón y Cajal 3, 47005 Valladolid, Spain.

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http://dx.doi.org/10.1016/j.cyto.2012.07.009DOI Listing
November 2012

Immunopathogenesis of 2009 pandemic influenza.

Enferm Infecc Microbiol Clin 2012 Oct;30 Suppl 4:18-24

Unidad de Investigación Médica en Infección e Inmunidad (IMI), Investigación Biomédica del Clínico (ibC), Hospital Clínico Universitario, Valladolid, Spain.

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http://dx.doi.org/10.1016/S0213-005X(12)70100-3DOI Listing
October 2012

A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis.

Cytokine 2012 Mar 23;57(3):332-6. Epub 2011 Dec 23.

Critical Care Medicine Service, Hospital Clínico Universitario-SACYL/SEMICYUC, Avda Ramón y Cajal 3, 47005 Valladolid, Spain.

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http://dx.doi.org/10.1016/j.cyto.2011.12.002DOI Listing
March 2012

[Gene expression profiling in the first twelve weeks of treatment in chronic hepatitis C patients].

Enferm Infecc Microbiol Clin 2011 Oct 30;29(8):573-80. Epub 2011 Jun 30.

Unidad de Investigación en Infección e Inmunidad, Servicio de Microbiología, Hospital Clínico Universitario, IECSCYL, Valladolid, España.

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http://dx.doi.org/10.1016/j.eimc.2011.04.006DOI Listing
October 2011

Pro- and anti-inflammatory responses are regulated simultaneously from the first moments of septic shock.

Eur Cytokine Netw 2011 Jun;22(2):82-7

Anesthesiology and Reanimation Service, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

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http://dx.doi.org/10.1684/ecn.2011.0281DOI Listing
June 2011

Host response cytokine signatures in viral and nonviral acute exacerbations of chronic obstructive pulmonary disease.

J Interferon Cytokine Res 2011 May 15;31(5):409-13. Epub 2011 Jan 15.

Translational Medicine Program, Infection and Immunity Unit, Microbiology Service, Hospital Clínico Universitario-IECSCYL, Valladolid, Spain.

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http://dx.doi.org/10.1089/jir.2010.0131DOI Listing
May 2011

Prolonged standard treatment for systemic lupus erythematosus fails to normalize the secretion of innate immunity-related chemokines.

Eur Cytokine Netw 2010 Mar;21(1):71-6

Unidad de Enfermedades Autoinmunes, Servicio de Medicina Interna, Hospital Clínico Universitario, Valladolid, Spain.

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http://dx.doi.org/10.1684/ecn.2009.0176DOI Listing
March 2010