Publications by authors named "Raphael Pelossof"

14Publications

A rectal cancer organoid platform to study individual responses to chemoradiation.

Authors:
Karuna Ganesh Chao Wu Kevin P O'Rourke Bryan C Szeglin Youyun Zheng Charles-Etienne Gabriel Sauvé Mohammad Adileh Isaac Wasserman Michael R Marco Amanda S Kim Maha Shady Francisco Sanchez-Vega Wouter R Karthaus Helen H Won Seo-Hyun Choi Raphael Pelossof Afsar Barlas Peter Ntiamoah Emmanouil Pappou Arthur Elghouayel James S Strong Chin-Tung Chen Jennifer W Harris Martin R Weiser Garrett M Nash Jose G Guillem Iris H Wei Richard N Kolesnick Harini Veeraraghavan Eduardo J Ortiz Iva Petkovska Andrea Cercek Katia O Manova-Todorova Leonard B Saltz Jessica A Lavery Ronald P DeMatteo Joan Massagué Philip B Paty Rona Yaeger Xi Chen Sujata Patil Hans Clevers Michael F Berger Scott W Lowe Jinru Shia Paul B Romesser Lukas E Dow Julio Garcia-Aguilar Charles L Sawyers J Joshua Smith

Nat Med 2019 10 7;25(10):1607-1614. Epub 2019 Oct 7.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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October 2019

Radiogenomics of rectal adenocarcinoma in the era of precision medicine: A pilot study of associations between qualitative and quantitative MRI imaging features and genetic mutations.

Authors:
Natally Horvat Harini Veeraraghavan Raphael A Pelossof Maria Clara Fernandes Arshi Arora Monika Khan Michael Marco Chin-Tung Cheng Mithat Gonen Jennifer S Golia Pernicka Marc J Gollub Julio Garcia-Aguillar Iva Petkovska

Eur J Radiol 2019 Apr 18;113:174-181. Epub 2019 Feb 18.

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

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April 2019

MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer.

Authors:
Ofra Novoplansky Matthew Fury Manu Prasad Ksenia Yegodayev Jonathan Zorea Limor Cohen Raphael Pelossof Liz Cohen Nora Katabi Fabiola Cecchi Ben-Zion Joshua Aron Popovtzer Jose Baselga Maurizio Scaltriti Moshe Elkabets

Int J Cancer 2019 08 11;145(3):748-762. Epub 2019 Feb 11.

The Shraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

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August 2019

Genomic Landscape of Pancreatic Adenocarcinoma in Younger versus Older Patients: Does Age Matter?

Authors:
Irit Ben-Aharon Moshe Elkabets Raphael Pelossof Kenneth H Yu Christine A Iacubuzio-Donahue Steven D Leach Maeve A Lowery Karyn A Goodman Eileen M O'Reilly

Clin Cancer Res 2019 04 7;25(7):2185-2193. Epub 2019 Jan 7.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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April 2019

Consolidation mFOLFOX6 Chemotherapy After Chemoradiotherapy Improves Survival in Patients With Locally Advanced Rectal Cancer: Final Results of a Multicenter Phase II Trial.

Authors:
Michael R Marco Lihong Zhou Sujata Patil Jorge E Marcet Madhulika G Varma Samuel Oommen Peter A Cataldo Steven R Hunt Anjali Kumar Daniel O Herzig Alessandro Fichera Blase N Polite Neil H Hyman Charles A Ternent Michael J Stamos Alessio Pigazzi David Dietz Yuliya Yakunina Raphael Pelossof Julio Garcia-Aguilar

Dis Colon Rectum 2018 Oct;61(10):1146-1155

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.

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October 2018

An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data.

Authors:
Mark Carty Lee Zamparo Merve Sahin Alvaro González Raphael Pelossof Olivier Elemento Christina S Leslie

Nat Commun 2017 05 17;8:15454. Epub 2017 May 17.

Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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May 2017

Prediction of potent shRNAs with a sequential classification algorithm.

Authors:
Raphael Pelossof Lauren Fairchild Chun-Hao Huang Christian Widmer Vipin T Sreedharan Nishi Sinha Dan-Yu Lai Yuanzhe Guan Prem K Premsrirut Darjus F Tschaharganeh Thomas Hoffmann Vishal Thapar Qing Xiang Ralph J Garippa Gunnar Rätsch Johannes Zuber Scott W Lowe Christina S Leslie Christof Fellmann

Nat Biotechnol 2017 04 6;35(4):350-353. Epub 2017 Mar 6.

Mirimus Inc., Woodbury, New York, USA.

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April 2017

KRAS and Combined KRAS/TP53 Mutations in Locally Advanced Rectal Cancer are Independently Associated with Decreased Response to Neoadjuvant Therapy.

Authors:
Oliver S Chow Deborah Kuk Metin Keskin J Joshua Smith Niedzica Camacho Raphael Pelossof Chin-Tung Chen Zhenbin Chen Karin Avila Martin R Weiser Michael F Berger Sujata Patil Emily Bergsland Julio Garcia-Aguilar

Ann Surg Oncol 2016 08 28;23(8):2548-55. Epub 2016 Mar 28.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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August 2016

Reply to Cristóbal and Co-authors' comment, deregulation of miR-92a in locally advanced rectal cancer.

Authors:
Raphael Pelossof Oliver Chow Julio Garcia-Aguilar

Genes Chromosomes Cancer 2016 07 2;55(7):613. Epub 2016 May 2.

Memorial Sloan Kettering Cancer Center, New York, NY.

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July 2016

Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer.

Authors:
Raphael Pelossof Oliver S Chow Lauren Fairchild J Joshua Smith Manu Setty Chin-Tung Chen Zhenbin Chen Fumiko Egawa Karin Avila Christina S Leslie Julio Garcia-Aguilar

Genes Chromosomes Cancer 2016 Apr;55(4):311-321

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.

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April 2016

Affinity regression predicts the recognition code of nucleic acid-binding proteins.

Authors:
Raphael Pelossof Irtisha Singh Julie L Yang Matthew T Weirauch Timothy R Hughes Christina S Leslie

Nat Biotechnol 2015 Dec 16;33(12):1242-1249. Epub 2015 Nov 16.

Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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December 2015

AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas.

Authors:
Moshe Elkabets Evangelos Pazarentzos Dejan Juric Qing Sheng Raphael A Pelossof Samuel Brook Ana Oaknin Benzaken Jordi Rodon Natasha Morse Jenny Jiacheng Yan Manway Liu Rita Das Yan Chen Angela Tam Huiqin Wang Jinsheng Liang Joseph M Gurski Darcy A Kerr Rafael Rosell Cristina Teixidó Alan Huang Ronald A Ghossein Neal Rosen Trever G Bivona Maurizio Scaltriti José Baselga

Cancer Cell 2015 Apr;27(4):533-46

Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA. Electronic address:

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April 2015

Linking signaling pathways to transcriptional programs in breast cancer.

Authors:
Hatice U Osmanbeyoglu Raphael Pelossof Jacqueline F Bromberg Christina S Leslie

Genome Res 2014 Nov 2;24(11):1869-80. Epub 2014 Sep 2.

Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA;

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November 2014

Impact of RNA-guided technologies for target identification and deconvolution.

Authors:
Myles Fennell Qing Xiang Alexia Hwang Chong Chen Chun-Hao Huang Chi-Chao Chen Raphael Pelossof Ralph J Garippa

J Biomol Screen 2014 Dec 27;19(10):1327-37. Epub 2014 Aug 27.

RNAi Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY, USA Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

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December 2014