Raphael Métivier

Raphael Métivier

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Raphael Métivier

Raphael Métivier

Publications by authors named "Raphael Métivier"

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Lymphatic Vasculature Requires Estrogen Receptor-α Signaling to Protect From Lymphedema.

Arterioscler Thromb Vasc Biol 2018 06 12;38(6):1346-1357. Epub 2018 Apr 12.

From the Institute of Metabolic and Cardiovascular Diseases of Toulouse, Université de Toulouse (F.M., F.T., F.P., A.C.G., F.D.T., F.B., E.L., A.C.P., F.L., B.G.-S.)

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http://dx.doi.org/10.1161/ATVBAHA.118.310997DOI Listing
June 2018

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications.

Physiol Rev 2017 07;97(3):1045-1087

I2MC, Institut National de la Santé et de la Recherche Médicale (INSERM) U 1048, Université de Toulouse 3 and CHU de Toulouse, Toulouse, France; Equipe SP@RTE UMR 6290 CNRS, Institut de Genétique et Développement de Rennes, Université de Rennes 1, Campus de Beaulieu, Rennes, France; Université de Rennes 1, Institut de Recherche en Santé, Environnement et Travail (Irest-INSERM UMR 1085), Equipe TREC, Rennes, France; Unité Mixte de Recherche 6214, Centre National de la Recherche Scientifique, Angers, France; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Collège de France, Université de Strasbourg, Illkirch, France; Departments of Physiology and Cell Biology and of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.

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http://dx.doi.org/10.1152/physrev.00024.2016DOI Listing
July 2017

Cytosine modifications modulate the chromatin architecture of transcriptional enhancers.

Genome Res 2017 06 10;27(6):947-958. Epub 2017 Apr 10.

CNRS UMR6290, Equipe SP@RTE, Institut de Génétique et Développement de Rennes, Campus de Beaulieu, 35042 Rennes Cedex, France.

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http://dx.doi.org/10.1101/gr.211466.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453328PMC
June 2017

Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment.

Mol Endocrinol 2016 Jul 10;30(7):709-32. Epub 2016 May 10.

Equipe Spatio-Temporal Regulation of Transcription in Eukaryotes (SP@RTE) (G.P., C.L.P., S.A., G.S., R.M.), Unité Mixte de Recherche 6290 Centre National de la Recherche Scientifique (Institut de Genétique et Développement de Rennes), Université de Rennes 1, Campus de Beaulieu, and Equipe Transcription, Environment and Cancer (TREC) (G.F.), Inserm U1085-Institut de Recherche en Santé, Environnement et Travail, Rennes 35042 Cedex, France; and Equipe 9 "Estrogen Receptor: In Vivo Dissection and Modulation" (A.F., R.S., F.L., C.F., J.-F.A.), Inserm Unité 1048 (Institut des Maladies Métaboliques et Cardiovasculaires), Toulouse 31432 Cedex 4, France.

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http://dx.doi.org/10.1210/me.2015-1311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426578PMC
July 2016

Coxsackie and adenovirus receptor is a target and a mediator of estrogen action in breast cancer.

Endocr Relat Cancer 2011 Jun 2;18(3):311-21. Epub 2011 Apr 2.

INSERM, U844, Hôpital Saint Eloi, Montpellier F-34091, France.

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http://dx.doi.org/10.1530/ERC-10-0230DOI Listing
June 2011

Repression of the estrogen receptor-alpha transcriptional activity by the Rho/megakaryoblastic leukemia 1 signaling pathway.

J Biol Chem 2009 Dec 13;284(49):33729-39. Epub 2009 Oct 13.

Equipe Récepteurs des Estrogènes et Destinée Cellulaire, UMR CNRS 6026, Université de Rennes I, Campus de Beaulieu, 35042 Rennes Cedex, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.045534
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http://dx.doi.org/10.1074/jbc.M109.045534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797142PMC
December 2009

Defining specificity of transcription factor regulatory activities.

J Cell Sci 2009 Nov;122(Pt 22):4027-34

Université de Rennes I, CNRS, UMR 6026, Equipe SPARTE, 35042 Rennes Cedex, France.

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http://jcs.biologists.org/content/joces/122/22/4027.full.pdf
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http://jcs.biologists.org/cgi/doi/10.1242/jcs.054916
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http://dx.doi.org/10.1242/jcs.054916DOI Listing
November 2009

Functional connection between deimination and deacetylation of histones.

Mol Cell Biol 2009 Sep 6;29(18):4982-93. Epub 2009 Jul 6.

Free University of Brussels, Faculty of Medicine, Laboratory of Cancer Epigenetics, Brussels, Belgium.

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http://dx.doi.org/10.1128/MCB.00285-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738279PMC
September 2009

New stably transfected bioluminescent cells expressing FLAG epitope-tagged estrogen receptors to study their chromatin recruitment.

BMC Biotechnol 2009 Sep 9;9:77. Epub 2009 Sep 9.

IRCM, Institut de Recherche en Cancérologie de Montpellier, F-34298; INSERM, U896, F-34298; Université Montpellier1, F-34298; CRLC Val d'Aurelle Paul Lamarque, Montpellier, F-34298, France.

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http://dx.doi.org/10.1186/1472-6750-9-77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749030PMC
September 2009

Marking time: the dynamic role of chromatin and covalent modification in transcription.

Int J Biochem Cell Biol 2009 Jan 2;41(1):155-63. Epub 2008 Sep 2.

European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.biocel.2008.08.028DOI Listing
January 2009

COUP-TFI modulates estrogen signaling and influences proliferation, survival and migration of breast cancer cells.

Breast Cancer Res Treat 2008 Jul 3;110(1):69-83. Epub 2007 Aug 3.

Endocrinologie Moléculaire de la Reproduction, UMR CNRS 6026-Interactions Cellulaires et Moléculaires, Université de Rennes 1, Campus de Beaulieu, 35042, Rennes cedex, France.

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http://dx.doi.org/10.1007/s10549-007-9693-6DOI Listing
July 2008

Cyclical DNA methylation of a transcriptionally active promoter.

Nature 2008 Mar;452(7183):45-50

Université de Rennes I, CNRS, UMR 6026 Equipe SPARTE, IFR 140 GFAS, Campus de Beaulieu, 35042 Rennes cedex, France.

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http://dx.doi.org/10.1038/nature06544DOI Listing
March 2008

Transient cyclical methylation of promoter DNA.

Nature 2008 Mar;452(7183):112-5

European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature06640DOI Listing
March 2008

CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.

Mol Endocrinol 2008 Feb 11;22(2):263-72. Epub 2007 Oct 11.

Department of Cancer Biology, The Scripps Research Institute, Jupiter, FL 33458, USA.

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http://dx.doi.org/10.1210/me.2007-0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234588PMC
February 2008

Deoxyribonucleic acid methyl transferases 3a and 3b associate with the nuclear orphan receptor COUP-TFI during gene activation.

Mol Endocrinol 2007 Sep 19;21(9):2085-98. Epub 2007 Jun 19.

Unité Mixte de Recherche 6026, Centre National de la Recherche Scientifique, Université Rennes I, Institut Fédératif de Recherche 140 Génomique Fonctionnelle Agronomie Santé, Equipe Information et Programmation Cellulaire, France.

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http://dx.doi.org/10.1210/me.2006-0490DOI Listing
September 2007

Sequential recruitment and combinatorial assembling of multiprotein complexes in transcriptional activation.

Phys Rev Lett 2006 May 18;96(19):198102. Epub 2006 May 18.

Centre for Nonlinear Dynamics, McGill University, Canada.

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http://dx.doi.org/10.1103/PhysRevLett.96.198102DOI Listing
May 2006

Transcription in four dimensions: nuclear receptor-directed initiation of gene expression.

EMBO Rep 2006 Feb;7(2):161-7

UMR CNRS 6026 (ICM), Equipe EMR, Université de Rennes I, Campus de Beaulieu, 35042 Rennes Cedex, France.

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http://dx.doi.org/10.1038/sj.embor.7400626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369254PMC
February 2006

The human estrogen receptor-alpha isoform hERalpha46 antagonizes the proliferative influence of hERalpha66 in MCF7 breast cancer cells.

Endocrinology 2005 Dec 8;146(12):5474-84. Epub 2005 Sep 8.

Equipe d'Endocrinologie Moléculaire de la Reproduction, Unité Mixte de Recherche Centre National de la Recherche Scientifique 6026, Rennes, France.

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http://dx.doi.org/10.1210/en.2005-0866DOI Listing
December 2005

Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus.

Mol Cell Biol 2005 Jul;25(13):5417-28

Department of Physiology, 1300 University Ave., 120 SMI, University of Wisconsin--Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1128/MCB.25.13.5417-5428.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156995PMC
July 2005

Genome-wide identification of high-affinity estrogen response elements in human and mouse.

Mol Endocrinol 2004 Jun 4;18(6):1411-27. Epub 2004 Mar 4.

Département de Biochimie, Université de Montréal, Montréal, Québec, Canada H3C 3J7.

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http://dx.doi.org/10.1210/me.2003-0441DOI Listing
June 2004

The relative contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha transcriptional activity depends upon the differentiation stage of the cell.

J Biol Chem 2004 Jun 12;279(25):26184-91. Epub 2004 Apr 12.

Endocrinologie Moleculaire de la Reproduction, UMR CNRS 6026, Universite de Rennes I, 35042 Rennes cedex, France.

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http://dx.doi.org/10.1074/jbc.M402148200DOI Listing
June 2004

[Activation of gene transcription].

Med Sci (Paris) 2004 Apr;20(4):391-3

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http://dx.doi.org/10.1051/medsci/2004204391DOI Listing
April 2004

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter.

Cell 2003 Dec;115(6):751-63

European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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http://dx.doi.org/10.1016/s0092-8674(03)00934-6DOI Listing
December 2003

Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.

EMBO J 2002 Jul;21(13):3443-53

Equipe d'Endocrinologie Moléculaire de la Reproduction, UMR CNRS 6026, Université de Rennes I, 35042 Rennes Cedex, France.

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http://dx.doi.org/10.1093/emboj/cdf344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126093PMC
July 2002

Multiple phosphorylation events control chicken ovalbumin upstream promoter transcription factor I orphan nuclear receptor activity.

Mol Endocrinol 2002 Jun;16(6):1332-51

Equipe Information et Programmation Cellulaire, Unité Mixte de Recherche 6026 Centre National de la Recherche Scientifique, Université de Rennes I, Campus de Beaulieu, 35042 Rennes Cedex, France.

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http://dx.doi.org/10.1210/mend.16.6.0840DOI Listing
June 2002