Publications by authors named "Raoul J de Groot"

45Publications

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity.

Proc Natl Acad Sci U S A 2020 10 29;117(41):25759-25770. Epub 2020 Sep 29.

Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands;

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October 2020

Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.

Nat Commun 2020 09 16;11(1):4646. Epub 2020 Sep 16.

Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CH, Utrecht, The Netherlands.

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September 2020

Essential Role of Enterovirus 2A Protease in Counteracting Stress Granule Formation and the Induction of Type I Interferon.

J Virol 2019 05 1;93(10). Epub 2019 May 1.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands

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May 2019

Human coronaviruses OC43 and HKU1 bind to 9--acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.

Proc Natl Acad Sci U S A 2019 02 24;116(7):2681-2690. Epub 2019 Jan 24.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands;

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February 2019

Small molecule ISRIB suppresses the integrated stress response within a defined window of activation.

Proc Natl Acad Sci U S A 2019 02 23;116(6):2097-2102. Epub 2019 Jan 23.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands;

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February 2019

Foot-and-Mouth Disease Virus Leader Protease Cleaves G3BP1 and G3BP2 and Inhibits Stress Granule Formation.

J Virol 2019 01 4;93(2). Epub 2019 Jan 4.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands

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January 2019

Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.

Cell Host Microbe 2017 Mar;21(3):356-366

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, the Netherlands. Electronic address:

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March 2017

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses.

PLoS Pathog 2016 Oct 26;12(10):e1005982. Epub 2016 Oct 26.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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October 2016

Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.

Proc Natl Acad Sci U S A 2016 May 16;113(22):E3111-9. Epub 2016 May 16.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands;

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May 2016

Bitter-sweet symphony: glycan-lectin interactions in virus biology.

FEMS Microbiol Rev 2014 Jul 6;38(4):598-632. Epub 2013 Dec 6.

Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

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July 2014

Quantum dot nanometal surface energy transfer based biosensing of sialic acid compositions and linkages in biological samples.

Anal Chem 2013 Apr 2;85(8):3864-70. Epub 2013 Apr 2.

Glycobiology Research and Training Center, Department of Medicine, University of California, San Diego, La Jolla, California, United States.

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April 2013

The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture.

PLoS Pathog 2012 Jan 26;8(1):e1002492. Epub 2012 Jan 26.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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January 2012

Attachment of mouse hepatitis virus to O-acetylated sialic acid is mediated by hemagglutinin-esterase and not by the spike protein.

J Virol 2010 Sep 10;84(17):8970-4. Epub 2010 Jun 10.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, Netherlands.

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September 2010

The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity.

Virology 2010 Jul 2;403(1):17-25. Epub 2010 May 2.

Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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July 2010

Feline infectious peritonitis: insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene.

J Gen Virol 2010 Feb 4;91(Pt 2):415-20. Epub 2009 Nov 4.

Virology Division, Department of Infectious Diseases and Immunology, Veterinary Faculty, Utrecht University, Utrecht, The Netherlands.

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February 2010

Experimental infection with neuropathogenic equid herpesvirus type 1 (EHV-1) in adult horses.

Vet J 2010 Nov 1;186(2):180-7. Epub 2009 Sep 1.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, Colorado 80523, USA.

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November 2010

Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases.

Proc Natl Acad Sci U S A 2009 Sep 31;106(37):15897-902. Epub 2009 Aug 31.

Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands.

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September 2009

Gain, preservation, and loss of a group 1a coronavirus accessory glycoprotein.

J Virol 2008 Oct 30;82(20):10312-7. Epub 2008 Jul 30.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.

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October 2008

Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution.

Proc Natl Acad Sci U S A 2008 Jul 11;105(26):9065-9. Epub 2008 Jun 11.

Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Sciences, Utrecht University, 3584 CL, Utrecht, The Netherlands.

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July 2008

Structure, function and evolution of the hemagglutinin-esterase proteins of corona- and toroviruses.

Authors:
Raoul J de Groot

Glycoconj J 2006 Feb;23(1-2):59-72

Virology Section, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.

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February 2006

Characterization of a torovirus main proteinase.

J Virol 2006 Apr;80(8):4157-67

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.

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April 2006

Expression of hemagglutinin esterase protein from recombinant mouse hepatitis virus enhances neurovirulence.

J Virol 2005 Dec;79(24):15064-73

Department of Microbiology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6076, USA.

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December 2005

Torovirus non-discontinuous transcription: mutational analysis of a subgenomic mRNA promoter.

J Virol 2005 Jul;79(13):8275-81

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.

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July 2005

Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS).

Int J Antimicrob Agents 2005 May;25(5):419-26

Eijkman-Winkler Center, Hp G04.614, University Medical Center Utrecht, Heidelberglaan 100, NL-3584 CX Utrecht, The Netherlands.

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May 2005

Natural history of a recurrent feline coronavirus infection and the role of cellular immunity in survival and disease.

J Virol 2005 Jan;79(2):1036-44

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.

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January 2005

Nidovirus sialate-O-acetylesterases: evolution and substrate specificity of coronaviral and toroviral receptor-destroying enzymes.

J Biol Chem 2005 Feb 26;280(8):6933-41. Epub 2004 Oct 26.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.

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February 2005

Three-color flow cytometry detection of virus-specific CD4+ and CD8+ T cells in the cat.

J Immunol Methods 2004 Feb;285(1):41-54

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.

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February 2004

The Genome Organization of the Nidovirales: Similarities and Differences between Arteri-, Toro-, and Coronaviruses.

Semin Virol 1997 Feb 25;8(1):33-47. Epub 2002 May 25.

Virology Unit, Department of Infectious Diseases and Immunology, Veterinary Faculty, Utrecht University, Yalelaan 1, 3584 CL, Utrecht, The Netherlands.

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February 1997