Randall S Johnson

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Glycolytic Response to Inflammation Over Time: Role of Myeloid HIF-1alpha.

Front Physiol 2018 22;9:1624. Epub 2018 Nov 22.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.3389/fphys.2018.01624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262152PMC
November 2018

The role of Olfr78 in the breathing circuit of mice.

Nature 2018 09 26;561(7724):E33-E40. Epub 2018 Sep 26.

Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.

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http://dx.doi.org/10.1038/s41586-018-0545-9DOI Listing
September 2018

The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.

Cell Metab 2018 04;27(4):898-913.e7

Physiological Laboratory, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm SE-171 77, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183013
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http://dx.doi.org/10.1016/j.cmet.2018.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887987PMC
April 2018

HIF-2α is essential for carotid body development and function.

Elife 2018 04 19;7. Epub 2018 Apr 19.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.7554/eLife.34681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916566PMC
April 2018

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.

Cancer Cell 2017 11;32(5):669-683.e5

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK; Department of Cell and Molecular Biology, Karolinska Institute, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691891PMC
November 2017

Cardiovascular adaptation to hypoxia and the role of peripheral resistance.

Elife 2017 10 19;6. Epub 2017 Oct 19.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.7554/eLife.28755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648530PMC
October 2017

Lorenz Poellinger.

Exp Cell Res 2017 07;356(2):115

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http://dx.doi.org/10.1016/j.yexcr.2017.05.026DOI Listing
July 2017

Profile of William Kaelin, Peter Ratcliffe, and Greg Semenza, 2016 Albert Lasker Basic Medical Research Awardees.

Proc Natl Acad Sci U S A 2016 12 28;113(49):13938-13940. Epub 2016 Nov 28.

Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3EG, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1617222113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150394PMC
December 2016

To PFKFB3 or Not to PFKFB3, That Is the Question.

Cancer Cell 2016 12;30(6):831

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK; Department of Cell and Molecular Biology, The Karolinska Institute, Stockholm S-171 77, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.007DOI Listing
December 2016

Constitutive Glycolytic Metabolism Supports CD8 T Cell Effector Memory Differentiation during Viral Infection.

Immunity 2016 11 8;45(5):1024-1037. Epub 2016 Nov 8.

Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130099PMC
November 2016

Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell Behavior.

Front Cell Dev Biol 2016 21;4:99. Epub 2016 Sep 21.

Department of Physiology, Development and Neuroscience, University of CambridgeCambridge, UK; Department of Cell and Molecular Biology, Karolinska InstitutetStockholm, Sweden.

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http://dx.doi.org/10.3389/fcell.2016.00099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030275PMC
September 2016

HIF2α-arginase axis is essential for the development of pulmonary hypertension.

Proc Natl Acad Sci U S A 2016 08 18;113(31):8801-6. Epub 2016 Jul 18.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, United Kingdom; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm SE-171 77, Sweden

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http://dx.doi.org/10.1073/pnas.1602978113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978263PMC
August 2016

Diverse roles of cell-specific hypoxia-inducible factor 1 in cancer-associated hypercoagulation.

Blood 2016 Mar 23;127(10):1355-60. Epub 2015 Dec 23.

Department of Physiology, Development and Neuroscience and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1182/blood-2015-09-671982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343824PMC
March 2016

Cutaneous control of blood pressure.

Curr Opin Nephrol Hypertens 2016 Jan;25(1):11-5

aDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK bDivision of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA cInterdisciplinary Center for Clinical Research, Friedrich-Alexander-University, Erlangen-Nürnberg, Germany dUniversity Department of Dermatology, University of Edinburgh, Lauriston Building, Lauriston Place, Edinburgh, UK.

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http://dx.doi.org/10.1097/MNH.0000000000000188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432654PMC
January 2016

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells.

J Natl Cancer Inst 2015 Oct 21;107(10). Epub 2015 Aug 21.

Department of Medical Biochemistry and Biophysics, Division of Vascular Biology, Karolinska Institute, Stockholm, Sweden (JWH, TL, ML, YGI, HQ, MZ, MZA, IN, PR, GG); Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska University Hospital, Solna, Sweden (NPT, JP, JH, AÖ, JB); Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden (HR, RSJ); Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, UK (RSJ); Department of Molecular Medicine and Surgery, Urology Laboratory, Karolinska Institute, Stockholm, Sweden (MP); Department of Urology, Karolinska University Hospital, Solna, Sweden (MP).Current affiliation: Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland (HQ).

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http://dx.doi.org/10.1093/jnci/djv209DOI Listing
October 2015

Kidney injury is independent of endothelial HIF-1α.

J Mol Med (Berl) 2015 Aug 11;93(8):891-904. Epub 2015 Mar 11.

Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00109-015-1264-4DOI Listing
August 2015

Through a Clear Cell, Darkly: HIF2α/PLIN2-Maintained Fat Droplets Protect ccRCCs from ER Stress.

Cancer Discov 2015 Jun;5(6):584-5

Physiological Laboratory, University of Cambridge, Cambridge, United Kingdom.

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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-15-0480DOI Listing
June 2015

Suppression of erythropoiesis by dietary nitrate.

FASEB J 2015 Mar 24;29(3):1102-12. Epub 2014 Nov 24.

*Department of Physiology, Development, and Neuroscience and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom; and Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton, United Kingdom

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http://dx.doi.org/10.1096/fj.14-263004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422362PMC
March 2015

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.

Nat Commun 2015 Mar 20;6:6340. Epub 2015 Mar 20.

1] Cancer Immunology Branch, Department of System Cancer Science, National Cancer Center, 111 jungbalsan-ro, Kyunggi 410-769, Republic of Korea [2] Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 410-769, Republic of Korea.

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http://dx.doi.org/10.1038/ncomms7340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383004PMC
March 2015

WITHDRAWN: Loss of hepatic HIF-1α accelerates lipid accumulation by inhibiting peroxisomal fatty acid oxidation in nonalcoholic fatty liver disease.

J Hepatol 2015 Feb 10. Epub 2015 Feb 10.

Department of Life Sciences and Medical BioScience, Waseda University School of Advanced Science and Engineering, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.01.037DOI Listing
February 2015

HIF transcription factors, inflammation, and immunity.

Immunity 2014 Oct;41(4):518-28

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK; Department of Cell and Molecular Biology, Karolinska Institute, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346319PMC
October 2014

Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.

J Biol Chem 2014 Aug 25;289(32):22459-69. Epub 2014 Jun 25.

From the Department of Medical Biochemistry and Genetics, and MediCity Research Laboratory, University of Turku, 20520 Turku, Finland, the Department of Oncology, Turku University Hospital, 20520 Turku, Finland

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http://dx.doi.org/10.1074/jbc.M113.533497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139252PMC
August 2014

Gene-environment interaction demonstrates the vulnerability of the embryonic heart.

Dev Biol 2014 Jul 18;391(1):99-110. Epub 2014 Mar 18.

Developmental and Stem Cell Biology Division, Victor Chang Cardiac Research Institute, 405 Liverpool Street, Darlinghurst, Sydney, NSW 2010, Australia; St. Vincent׳s Clinical School, Faculty of Medicine, University of New South Wales, de Lacy Building, St. Vincent׳s Hospital, Darlinghurst, Sydney, NSW 2010, Australia; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2014.03.005DOI Listing
July 2014

A whiter shade of gray: HIF and coordination of angiogenesis with postnatal myelination.

Dev Cell 2014 Jul;30(2):116-7

Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.07.003DOI Listing
July 2014

Epidermal deletion of HIF-2α stimulates wound closure.

J Invest Dermatol 2014 Mar 13;134(3):801-808. Epub 2013 Sep 13.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877686PMC
March 2014

Endothelial hypoxic metabolism in carcinogenesis and dissemination: HIF-A isoforms are a NO metastatic phenomenon.

Oncotarget 2013 Dec;4(12):2567-76

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.

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http://www.oncotarget.com/fulltext/1461
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926849PMC
http://dx.doi.org/10.18632/oncotarget.1461DOI Listing
December 2013

Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy.

J Am Heart Assoc 2013 Dec 10;2(6):e000548. Epub 2013 Dec 10.

Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1161/JAHA.113.000548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886757PMC
December 2013

Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.

Nat Immunol 2013 Nov 29;14(11):1173-82. Epub 2013 Sep 29.

Division of Biological Sciences, Molecular Biology Section, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ni.2714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977965PMC
November 2013

HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination.

J Mol Med (Berl) 2013 Oct 19;91(10):1199-205. Epub 2013 May 19.

Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.

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http://link.springer.com/10.1007/s00109-013-1052-y
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http://dx.doi.org/10.1007/s00109-013-1052-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783576PMC
October 2013

HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.

Proc Natl Acad Sci U S A 2013 Oct 10;110(41):16568-73. Epub 2013 Sep 10.

Departments of Orthopedic Surgery, Integrated Bone Metabolism and Immunology, and Musculoskeletal Reconstruction and Regeneration Surgery, Keio Kanrinmaru Project, and Department of Dentistry and Oral Surgery, School of Medicine, Keio University, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1073/pnas.1308755110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799362PMC
October 2013

HIF isoforms in the skin differentially regulate systemic arterial pressure.

Proc Natl Acad Sci U S A 2013 Oct 7;110(43):17570-5. Epub 2013 Oct 7.

Departments of Physiology, Development and Neuroscience and Medicine, University of Cambridge CB2 3EG, Cambridge, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1306942110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808605PMC
October 2013

Hypoxia-inducible factor-1 is a determinant of lobular structure and oxygen consumption in the liver.

Microcirculation 2013 Jul;20(5):385-93

Department of Applied Physics and Physico-Informatics, Faculty of Science and Technology, Keio University, Kouhoku-ku, Yokohama, Japan.

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http://doi.wiley.com/10.1111/micc.12033
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http://dx.doi.org/10.1111/micc.12033DOI Listing
July 2013

Myeloid hypoxia-inducible factor-1α is essential for skeletal muscle regeneration in mice.

J Immunol 2013 Jul 31;191(1):407-14. Epub 2013 May 31.

Institut für Physiologie, Universität Duisburg-Essen, D-45122 Essen, Germany.

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http://dx.doi.org/10.4049/jimmunol.1103779DOI Listing
July 2013

Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.

Cell Stem Cell 2013 Jan;12(1):49-61

Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, Keio University School of Medicine, Shinano-machi, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.stem.2012.10.011DOI Listing
January 2013

Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α-dependent function.

Proc Natl Acad Sci U S A 2012 Oct 9;109(43):17478-83. Epub 2012 Oct 9.

Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1209281109
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http://dx.doi.org/10.1073/pnas.1209281109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491491PMC
October 2012

microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation.

Proc Natl Acad Sci U S A 2012 Aug 13;109(35):14030-4. Epub 2012 Aug 13.

Department of Dermatology, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1073/pnas.1111292109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435188PMC
August 2012

Loss of fibroblast HIF-1α accelerates tumorigenesis.

Cancer Res 2012 Jul 3;72(13):3187-95. Epub 2012 May 3.

Molecular Biology Section, Division of Biological Sciences, Department of Medicine, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089958PMC
July 2012

Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration.

Eur J Immunol 2012 May;42(5):1226-36

Molecular Immunology, IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.

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http://doi.wiley.com/10.1002/eji.201142053
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http://dx.doi.org/10.1002/eji.201142053DOI Listing
May 2012

HIF-mediated endothelial response during cancer progression.

Int J Hematol 2012 May 8;95(5):471-7. Epub 2012 May 8.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.

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http://link.springer.com/10.1007/s12185-012-1072-3
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http://dx.doi.org/10.1007/s12185-012-1072-3DOI Listing
May 2012

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression.

Nat Rev Cancer 2011 Dec 15;12(1):9-22. Epub 2011 Dec 15.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nrc3183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401912PMC
December 2011

Disruption of HIF-1α in hepatocytes impairs glucose metabolism in diet-induced obesity mice.

Biochem Biophys Res Commun 2011 Nov 22;415(3):445-9. Epub 2011 Oct 22.

Department of Obstetrics & Gynecology, School of Medicine, Keio University, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1101901
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http://dx.doi.org/10.1016/j.bbrc.2011.10.089DOI Listing
November 2011

Hypoxia and metastasis in breast cancer.

Curr Top Microbiol Immunol 2010 ;345:121-39

Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1007/82_2010_77DOI Listing
November 2010

O2 regulates stem cells through Wnt/β-catenin signalling.

Nat Cell Biol 2010 Oct 19;12(10):1007-13. Epub 2010 Sep 19.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://www.nature.com/articles/ncb2102
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http://dx.doi.org/10.1038/ncb2102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144143PMC
October 2010

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.

Cell Stem Cell 2010 Sep;7(3):391-402

Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.stem.2010.06.020DOI Listing
September 2010

Tumor vessels are Eph-ing complicated.

Cancer Cell 2010 Jun;17(6):533-4

Division of Biological Sciences, UC San Diego, La Jolla, CA 92093-0377, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15356108100020
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http://dx.doi.org/10.1016/j.ccr.2010.05.020DOI Listing
June 2010

VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis.

Am J Pathol 2010 May 9;176(5):2269-82. Epub 2010 Apr 9.

Department of Pathology and Laboratory Medicine, Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

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http://dx.doi.org/10.2353/ajpath.2010.090310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861092PMC
May 2010

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism.

Cell Metab 2010 May 15;11(5):364-78. Epub 2010 Apr 15.

Molecular Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.cmet.2010.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893150PMC
May 2010

Role of HIF-1alpha in skeletal development.

Ann N Y Acad Sci 2010 Mar;1192:322-6

Department of Orthopaedic Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05238.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047468PMC
March 2010

HIF-1alpha is necessary to support gluconeogenesis during liver regeneration.

Biochem Biophys Res Commun 2009 Oct 28;387(4):789-94. Epub 2009 Jul 28.

Department of Obstetrics & Gynecology, Keio University, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2009.07.115DOI Listing
October 2009

Interdependence of hypoxic and innate immune responses.

Nat Rev Immunol 2009 Sep;9(9):609-17

Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/nri2607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343208PMC
September 2009

Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia.

Blood 2009 Jul 19;114(4):844-59. Epub 2009 May 19.

Academic Unit of Inflammation and Tumour Targeting, Faculty of Medicine, Dentistry and Health,University of Sheffield, Beech Hill Road, Sheffield, United Kingdom.

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http://dx.doi.org/10.1182/blood-2008-12-195941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882173PMC
July 2009

You don't need a PHD to grow a tumor.

Dev Cell 2009 Jun;16(6):781-2

Molecular Biology Section, Division of Biological Sciences, University of California, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.devcel.2009.06.001DOI Listing
June 2009

Nonrenal regulation of EPO synthesis.

Kidney Int 2009 Apr 21;75(7):682-8. Epub 2009 Jan 21.

Division of Biology, University of California, San Diego, La Jolla, CA 92037-0377, USA.

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http://dx.doi.org/10.1038/ki.2008.687DOI Listing
April 2009

Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis.

Nature 2008 Dec 9;456(7223):814-8. Epub 2008 Nov 9.

Molecular Biology Section, Division of Biological Sciences, Moores Cancer Center, University of California, San Diego, San Diego, California 92093, USA.

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http://www.nature.com/doifinder/10.1038/nature07445
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http://dx.doi.org/10.1038/nature07445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103772PMC
December 2008

HIF-1: an age-dependent regulator of lens cell proliferation.

Invest Ophthalmol Vis Sci 2008 Nov 27;49(11):4961-70. Epub 2008 Jun 27.

Department of Ophthalmology and Visual Sciences, Washington University, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1167/iovs.08-2118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585414PMC
November 2008

Putting the tissue and environmental 'context' into differentiation and gene regulation.

Curr Opin Genet Dev 2008 Oct 4;18(5):395-6. Epub 2008 Nov 4.

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http://dx.doi.org/10.1016/j.gde.2008.10.003DOI Listing
October 2008

Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice.

Oncogene 2008 Sep 19;27(40):5354-8. Epub 2008 May 19.

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6144, USA.

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http://dx.doi.org/10.1038/onc.2008.160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575082PMC
September 2008

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis.

Development 2008 Sep 24;135(17):2939-48. Epub 2008 Jul 24.

Department of Biochemistry and Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1242/dev.021097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654719PMC
September 2008

Critical role of HIF-1alpha in keratinocyte defense against bacterial infection.

J Invest Dermatol 2008 Aug 6;128(8):1964-8. Epub 2008 Mar 6.

Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093-0377, USA.

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http://dx.doi.org/10.1038/jid.2008.27DOI Listing
August 2008

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.

Nature 2008 Jun 23;453(7196):807-11. Epub 2008 Apr 23.

Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0723, USA.

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http://dx.doi.org/10.1038/nature06905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669289PMC
June 2008

The role of HIF-1 in hypoxic response in the skeletal muscle.

Adv Exp Med Biol 2007 ;618:229-44

Molecular Biology Section, Division of Biological Sciences, UC San Diego, San Diego, California, USA.

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March 2008

Transgenic models to understand hypoxia-inducible factor function.

Methods Enzymol 2007 ;435:87-105

Molecular Biology Section, Division of Biological Sciences, University of California San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1016/S0076-6879(07)35005-2DOI Listing
February 2008

Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes.

J Infect Dis 2008 Jan;197(2):214-7

1Division of Pediatric Pharmacology and Drug Discovery, School of Medicine, University of California, San Diego, La Jolla 92093-0687, USA.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5248
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http://dx.doi.org/10.1086/524843DOI Listing
January 2008

Role of the hypoxia inducible factors HIF in iron metabolism.

Cell Cycle 2008 Jan;7(1):28-32

Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France.

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http://dx.doi.org/10.4161/cc.7.1.5145DOI Listing
January 2008

Hypoxia inducible factor (HIF) function in innate immunity and infection.

J Mol Med (Berl) 2007 Dec 21;85(12):1339-46. Epub 2007 Nov 21.

Division of Pediatric Pharmacology & Drug Discovery, University of California, San Diego School of Medicine, Cellular and Molecular Medicine East, Room 1066, 9500 Gilman Drive, MC 0687, La Jolla, CA 92093-0687, USA.

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http://dx.doi.org/10.1007/s00109-007-0282-2DOI Listing
December 2007

HIF-1alpha in endurance training: suppression of oxidative metabolism.

Am J Physiol Regul Integr Comp Physiol 2007 Nov 12;293(5):R2059-69. Epub 2007 Sep 12.

Div. of Biologicay, University of California, San Diego, La Jolla, CA 92093-0377, USA.

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http://dx.doi.org/10.1152/ajpregu.00335.2007DOI Listing
November 2007

HIF1alpha regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis.

Development 2007 Nov 3;134(21):3917-28. Epub 2007 Oct 3.

Department of Molecular Genetics, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel.

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http://dev.biologists.org/cgi/doi/10.1242/dev.008441
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http://dx.doi.org/10.1242/dev.008441DOI Listing
November 2007