Ramon Salazar

Ramon Salazar

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Ramon Salazar

Ramon Salazar

Publications by authors named "Ramon Salazar"

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A Phase 1 Trial of Oncolytic Adenovirus ICOVIR-5 Administered Intravenously to Cutaneous and Uveal Melanoma Patients.

Hum Gene Ther 2019 Mar 13;30(3):352-364. Epub 2018 Nov 13.

3 Department of Medical Oncology, Oncobell Program, Institut Català d'Oncologia-IDIBELL, L'Hospitalet, Barcelona, Spain.

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https://www.liebertpub.com/doi/10.1089/hum.2018.107
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http://dx.doi.org/10.1089/hum.2018.107DOI Listing
March 2019

Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms.

Neuroendocrinology 2019 28;108(1):18-25. Epub 2018 Aug 28.

Friedrich-Alexander Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1159/000493319DOI Listing
August 2018

Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer.

Am Soc Clin Oncol Educ Book 2018 May;38:231-238

From the Oncology Data Science Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain; Sage Bionetworks, Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Medical Oncology, Catalan Institute of Oncology, Oncobell Program, L'Hospitalet de Llobregat, CIBERONC, Barcelona, Spain; Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.

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http://ascopubs.org/doi/10.1200/EDBK_200929
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http://dx.doi.org/10.1200/EDBK_200929DOI Listing
May 2018

Factors Predicting Adherence to a Tailored-Dose Adjuvant Treatment on the Basis of Geriatric Assessment in Elderly People With Colorectal Cancer: A Prospective Study.

Clin Colorectal Cancer 2018 03 28;17(1):e59-e68. Epub 2017 Sep 28.

Department of Clinical Sciences, University of Barcelona and Institut d'Investigació Biomèdica de Bellvitge, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.clcc.2017.09.003DOI Listing
March 2018

Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component.

Br J Cancer 2017 Jul 6;117(3):421-431. Epub 2017 Jul 6.

Unit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO), CIBERESP, Gran Via 199, Hospitalet Llobregat, 08908 Barcelona, Spain.

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http://dx.doi.org/10.1038/bjc.2017.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537504PMC
July 2017

Gastrointestinal cancer: Light and shade of intrahepatic arterial radiotherapy in mCRC.

Nat Rev Clin Oncol 2016 08 14;13(8):467-8. Epub 2016 Jun 14.

Department of Medical Oncology, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Universitat de Barcelona, L'Hospitalet de Llobregat, Avinguda Granvia, 199-203, 08908 Barcelona, Spain.

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http://dx.doi.org/10.1038/nrclinonc.2016.92DOI Listing
August 2016

Multi-target angiokinase inhibitors to fight resistance.

Cell Cycle 2014 ;13(17):2649-50

a Tumor Angiogenesis Group ; Catalan Institute of Oncology (ICO)-Bellvitge Biomedical Research Institute ; Barcelona , Spain.

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http://dx.doi.org/10.4161/15384101.2014.954216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613648PMC
June 2016

Nanofluidic Digital PCR and Extended Genotyping of RAS and BRAF for Improved Selection of Metastatic Colorectal Cancer Patients for Anti-EGFR Therapies.

Mol Cancer Ther 2016 05 1;15(5):1106-12. Epub 2016 Apr 1.

Translational Research Laboratory, Catalan Insitute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain. Department of Medical Oncology, Catalan Insitute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0820DOI Listing
May 2016

Mutanome and expression of immune response genes in microsatellite stable colon cancer.

Oncotarget 2016 Apr;7(14):17711-25

Unit of Biomarkers and Susceptibility, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.7293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951244PMC
April 2016

Overcoming Resistance to Anti-EGFR Therapy in Colorectal Cancer.

Am Soc Clin Oncol Educ Book 2015 :e149-56

From the Sage Bionetworks, Fred Hutchinson Cancer Research Center, Seattle, WA; Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Medical Oncology, Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.14694/EdBook_AM.2015.35.e149DOI Listing
February 2016

Optimizing Anti-EGFR Therapy in Colorectal Cancer.

Clin Cancer Res 2015 Dec 13;21(24):5415-6. Epub 2015 Oct 13.

Dipartimento Medico-Chirurgico di internistica Clinica e Sperimentale "F. Magrassi e A. Lanzara", Seconda Università degli Studi di Napoli, Napoli, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1768DOI Listing
December 2015

The evolution of our molecular understanding of colorectal cancer: what we are doing now, what the future holds, and how tumor profiling is just the beginning.

Am Soc Clin Oncol Educ Book 2014 :91-9

From the Sage Bionetworks, Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Medical Oncology, Translational Research Laboratory, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain; Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.91DOI Listing
November 2015

Analysing black phosphorus transistors using an analytic Schottky barrier MOSFET model.

Nat Commun 2015 Nov 13;6:8948. Epub 2015 Nov 13.

Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907, USA.

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http://dx.doi.org/10.1038/ncomms9948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660372PMC
November 2015

Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer.

Clin Cancer Res 2015 Oct 12;21(20):4709-18. Epub 2015 Jun 12.

Unit of Biomarkers and Susceptibility, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, L'Hospitalet de Llobregat, Barcelona, Spain. Department of Clinical Sciences, Faculty of Medicine, University of Barcelona (UB), Barcelona, Spain.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-15-0159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609254PMC
October 2015

Personalizing colon cancer adjuvant therapy: selecting optimal treatments for individual patients.

J Clin Oncol 2015 Jun 27;33(16):1787-96. Epub 2015 Apr 27.

Rodrigo Dienstmann, Sage Bionetworks, Fred Hutchinson Cancer Research Center, Seattle, WA; Rodrigo Dienstmann and Josep Tabernero, Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona; and Ramon Salazar, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2014.60.0213DOI Listing
June 2015

Discovery and validation of new potential biomarkers for early detection of colon cancer.

PLoS One 2014 12;9(9):e106748. Epub 2014 Sep 12.

Unit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO) and CIBERESP, Hospitalet de Llobregat, Barcelona, Spain; Colorectal Cancer Group, Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona (UB), Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106748PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162553PMC
May 2015

BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.

Sci Signal 2015 Apr 21;8(373):ra38. Epub 2015 Apr 21.

Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Parc de Recerca Biomèdica de Barcelona, Barcelona 08003, Spain.

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http://dx.doi.org/10.1126/scisignal.2005886DOI Listing
April 2015

Genomic testing in colorectal cancer: how much is enough?

Oncology (Williston Park) 2015 Mar;29(3):186-8

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March 2015

Genomic classifier ColoPrint predicts recurrence in stage II colorectal cancer patients more accurately than clinical factors.

Oncologist 2015 Feb 5;20(2):127-33. Epub 2015 Jan 5.

Departments of Gastrointestinal Medical Oncology and Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Surgery, Klinikum Rechts der Isar, Technische University, Munich, Germany; Institut Català d'Oncologia, IDIBELL L'Hospitalet de Llobregat, Barcelona, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain; Department of Surgery, Medical University of Vienna, Vienna, Austria; Department of Surgery, University of Ferrara, Ferrara, Italy; Agendia NV, Amsterdam, The Netherlands; Agendia Inc., Irvine, California, USA.

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http://dx.doi.org/10.1634/theoncologist.2014-0325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319631PMC
February 2015

Intrinsic cancer subtypes--next steps into personalized medicine.

Cell Oncol (Dordr) 2015 Feb 14;38(1):3-16. Epub 2015 Jan 14.

Department of Medical Oncology, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Av. Gran Via 199-203, 08907, Barcelona, Spain.

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http://dx.doi.org/10.1007/s13402-014-0203-7DOI Listing
February 2015

Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.

PLoS One 2013 25;8(11):e80158. Epub 2013 Nov 25.

Cancer Prevention and Control Program, Catalan Institute of Oncology, Barcelona, Spain ; Colorectal Cancer Group, Bellvitge Biomedical Research Institute and Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080158PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839967PMC
January 2015

Paracrine network: another step in the complexity of resistance to EGFR blockade?

Clin Cancer Res 2014 Dec 19;20(24):6227-9. Epub 2014 Aug 19.

Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1615DOI Listing
December 2014

Identification of candidate susceptibility genes for colorectal cancer through eQTL analysis.

Carcinogenesis 2014 Sep 23;35(9):2039-46. Epub 2014 Apr 23.

Cancer Prevention and Control Program, Catalan Institute of Oncology, and Consortium for Biomedical Research on Epidemiology and Public Health (CIBERESP), Barcelona E08907, Spain, Colorectal Cancer Group, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona E08907, Spain, Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona E08907, Spain,

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http://dx.doi.org/10.1093/carcin/bgu092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146415PMC
September 2014

Large differences in global transcriptional regulatory programs of normal and tumor colon cells.

BMC Cancer 2014 Sep 24;14:708. Epub 2014 Sep 24.

Unit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO), Av Gran Via 199-203, E-08907 L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1186/1471-2407-14-708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182786PMC
September 2014

Phase 1 dose escalation and pharmacokinetic evaluation of oral gemcitabine prodrug (LY2334737) in combination with docetaxel in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2014 Jun 18;73(6):1205-15. Epub 2014 Apr 18.

Clinical Research Unit, Institut Català d'Oncologia-IDIBELL, L'Hospitalet de Llobregat, Ctra. Gran Vía, 08907 s/n., Barcelona, Spain,

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http://dx.doi.org/10.1007/s00280-014-2457-1DOI Listing
June 2014

New approaches but the same flaws in the search for prognostic signatures.

Clin Cancer Res 2014 Apr 28;20(8):2019-22. Epub 2014 Feb 28.

Authors' Affiliations: Department of Medical Oncology and Translational Research Laboratory, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat; and Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0219DOI Listing
April 2014

Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer.

Mol Cancer 2014 Mar 5;13:46. Epub 2014 Mar 5.

Unit of Biomarkers and Susceptibility, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1186/1476-4598-13-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023701PMC
March 2014

Toward low-power electronics: tunneling phenomena in transition metal dichalcogenides.

ACS Nano 2014 Feb 14;8(2):1681-9. Epub 2014 Jan 14.

Center for Nanoscale Material, Argonne National Laboratory , Lemont, Illinois 60439, United States.

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http://dx.doi.org/10.1021/nn406603hDOI Listing
February 2014

Tenth anniversary of bevacizumab in colorectal cancer: has it fulfilled its promise?

Future Oncol 2014 Feb;10(2):149-52

Medical Oncology Department, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.2217/fon.14.6DOI Listing
February 2014

Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer.

J Natl Cancer Inst 2014 Jan 22;106(1):djt322. Epub 2013 Nov 22.

Affiliations of authors: Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, Barcelona, Spain (CM, AM-C, FJC, ME); Medical Oncology Service, Catalan Institute of Oncology, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Barcelona, Spain (AM-C, EM-B, AA); Department of Medical Oncology (CS, RS) and Clinical Informatics Unit (VN-P), Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain; Department of Pathology, Germans Trias i Pujol Foundation, Barcelona, Spain (EM); Department of Hematology and Oncology, Ospedale Niguarda Ca' Granda, Milan, Italy (AS-B, AC, SS); Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain (EE, JT); Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Barcelona, Spain (ME); Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain (ME).

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http://dx.doi.org/10.1093/jnci/djt322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906989PMC
January 2014

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer.

Cancer Prev Res (Phila) 2013 Jul 21;6(7):656-65. Epub 2013 May 21.

Cancer Epigenetics and Biology Program (PEBC), Catalan Institute of Oncology (ICO-IDIBELL), Barcelona 08908, Spain.

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http://dx.doi.org/10.1158/1940-6207.CAPR-12-0501DOI Listing
July 2013

Association between habitual dietary flavonoid and lignan intake and colorectal cancer in a Spanish case-control study (the Bellvitge Colorectal Cancer Study).

Cancer Causes Control 2013 Mar 16;24(3):549-57. Epub 2012 May 16.

Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, Avda Gran Via 199-203, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1007/s10552-012-9992-zDOI Listing
March 2013

Gastroenteropancreatic neuroendocrine tumors: diagnosis and treatment.

Ann Gastroenterol 2013 ;26(1):29-36

Medical Oncology Department, Institut Català d'Oncologia, L'Hospitalet del Llobregat, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959515PMC
January 2013

Observation of 1D behavior in Si nanowires: toward high-performance TFETs.

Nano Lett 2012 Nov 8;12(11):5571-5. Epub 2012 Oct 8.

Birck Nanotechnology Center, Purdue University, 1205 W. State Street, West Lafayette, Indiana 47907, USA.

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http://dx.doi.org/10.1021/nl3025664DOI Listing
November 2012

Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.

Mol Carcinog 2012 Sep 30;51(9):746-53. Epub 2011 Aug 30.

Translational Research Laboratory, Institut Català d'Oncologia-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1002/mc.20843DOI Listing
September 2012

Phase II study of preoperative radiotherapy and concomitant weekly intravenous oxaliplatin combined with oral capecitabine for stages II-III rectal cancer.

Clin Transl Oncol 2012 Aug 11;14(8):592-8. Epub 2012 Jul 11.

Department of Medical Oncology, Institut Català d'Oncologia/IDIBELL, L'Hospitalet de Llobregat, Barcelona, Autovía Castelldefels, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12094-012-0846-7DOI Listing
August 2012

ENETS 2011 Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Tumors: an update.

Neuroendocrinology 2012 15;95(2):71-3. Epub 2012 Feb 15.

Institut Català D'Oncologia (IDIBELL), Barcelona, Spain.

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http://dx.doi.org/10.1159/000335600DOI Listing
June 2012

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

Nature 2012 Jan 26;483(7387):100-3. Epub 2012 Jan 26.

Division of Molecular Carcinogenesis, Center for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nature10868DOI Listing
January 2012

Phase I study of weekly plitidepsin as 1-hour infusion combined with carboplatin in patients with advanced solid tumors or lymphomas.

Invest New Drugs 2011 Dec 10;29(6):1406-13. Epub 2010 Jul 10.

Instituto Catalán de Oncología, Ctra. Gran Vía, s/n, L'Hospitalet de Llobregat, 08907, Barcelona, Spain.

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http://dx.doi.org/10.1007/s10637-010-9488-1DOI Listing
December 2011

SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours (GEP NETS).

Clin Transl Oncol 2011 Aug;13(8):545-51

Medical Oncology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.

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http://dx.doi.org/10.1007/s12094-011-0695-9DOI Listing
August 2011

Potential synergies for combined targeted therapy in the treatment of neuroendocrine cancer.

Drugs 2011 May;71(7):841-52

Institut Catal DOncologiaIDIBELL, LHospitalet-Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.2165/11585500-000000000-00000DOI Listing
May 2011

Innovations therapy: mammalian target of rapamycin (mTOR) inhibitors for the treatment of neuroendocrine tumors.

Cancer Metastasis Rev 2011 Mar;30 Suppl 1:27-34

Medical Oncology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s10555-011-9290-3DOI Listing
March 2011

Future perspectives on neuroendocrine tumors.

Cancer Metastasis Rev 2011 Mar;30 Suppl 1:35-40

Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain.

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http://dx.doi.org/10.1007/s10555-011-9294-zDOI Listing
March 2011

Molecular targeted therapies in the treatment of gastroenteropancreatic neuroendocrine tumors.

Target Oncol 2009 Dec 7;4(4):287-96. Epub 2009 Nov 7.

Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1007/s11523-009-0128-7DOI Listing
December 2009