Dr. Ramiro Ramirez-Solis, PhD - The Wellcome Trust Sanger Institute - Head of Mouse Pipelines

Dr. Ramiro Ramirez-Solis

PhD

The Wellcome Trust Sanger Institute

Head of Mouse Pipelines

United Kingdom

Dr. Ramiro Ramirez-Solis, PhD - The Wellcome Trust Sanger Institute - Head of Mouse Pipelines

Dr. Ramiro Ramirez-Solis

PhD

Introduction

Primary Affiliation: The Wellcome Trust Sanger Institute - United Kingdom

Publications

27Publications

987Reads

-Profile Views

1097PubMed Central Citations

Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia.

Exp Hematol 2014 Dec 12;42(12):1053-8.e1. Epub 2014 Aug 12.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2014.07.269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271779PMC
December 2014
36 Reads
2 Citations
2.480 Impact Factor

Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.

PLoS Genet 2014 Oct 23;10(10):e1004705. Epub 2014 Oct 23.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia; Department of Anatomy and Developmental Biology, Monash University, Clayton, Melbourne, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1004705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207618PMC
October 2014
18 Reads
8 Citations

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.

Nat Commun 2014 Apr 11;5:3540. Epub 2014 Apr 11.

Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms4540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996542PMC
April 2014
19 Reads
14 Citations
10.742 Impact Factor

Genomic analysis of a novel spontaneous albino C57BL/6N mouse strain.

Genesis 2013 Jul 25;51(7):523-8. Epub 2013 May 25.

The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, United Kingdom.

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http://dx.doi.org/10.1002/dvg.22398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799019PMC
July 2013
22 Reads
2 Citations

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice.

Mamm Genome 2013 Jun 28;24(5-6):240-51. Epub 2013 May 28.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, UK.

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http://dx.doi.org/10.1007/s00335-013-9456-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685703PMC
June 2013
7 Reads
11 Citations
3.070 Impact Factor

Large-scale mouse knockouts and phenotypes.

Wiley Interdiscip Rev Syst Biol Med 2012 Nov-Dec;4(6):547-63. Epub 2012 Aug 15.

Mouse Pipelines, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1002/wsbm.1183DOI Listing
February 2013
5 Reads
4 Citations

Seventy-five genetic loci influencing the human red blood cell.

Authors:
Pim van der Harst Weihua Zhang Irene Mateo Leach Augusto Rendon Niek Verweij Joban Sehmi Dirk S Paul Ulrich Elling Hooman Allayee Xinzhong Li Aparna Radhakrishnan Sian-Tsung Tan Katrin Voss Christian X Weichenberger Cornelis A Albers Abtehale Al-Hussani Folkert W Asselbergs Marina Ciullo Fabrice Danjou Christian Dina Tõnu Esko David M Evans Lude Franke Martin Gögele Jaana Hartiala Micha Hersch Hilma Holm Jouke-Jan Hottenga Stavroula Kanoni Marcus E Kleber Vasiliki Lagou Claudia Langenberg Lorna M Lopez Leo-Pekka Lyytikäinen Olle Melander Federico Murgia Ilja M Nolte Paul F O'Reilly Sandosh Padmanabhan Afshin Parsa Nicola Pirastu Eleonora Porcu Laura Portas Inga Prokopenko Janina S Ried So-Youn Shin Clara S Tang Alexander Teumer Michela Traglia Sheila Ulivi Harm-Jan Westra Jian Yang Jing Hua Zhao Franco Anni Abdel Abdellaoui Antony Attwood Beverley Balkau Stefania Bandinelli François Bastardot Beben Benyamin Bernhard O Boehm William O Cookson Debashish Das Paul I W de Bakker Rudolf A de Boer Eco J C de Geus Marleen H de Moor Maria Dimitriou Francisco S Domingues Angela Döring Gunnar Engström Gudmundur Ingi Eyjolfsson Luigi Ferrucci Krista Fischer Renzo Galanello Stephen F Garner Bernd Genser Quince D Gibson Giorgia Girotto Daniel Fannar Gudbjartsson Sarah E Harris Anna-Liisa Hartikainen Claire E Hastie Bo Hedblad Thomas Illig Jennifer Jolley Mika Kähönen Ido P Kema John P Kemp Liming Liang Heather Lloyd-Jones Ruth J F Loos Stuart Meacham Sarah E Medland Christa Meisinger Yasin Memari Evelin Mihailov Kathy Miller Miriam F Moffatt Matthias Nauck Maria Novatchkova Teresa Nutile Isleifur Olafsson Pall T Onundarson Debora Parracciani Brenda W Penninx Lucia Perseu Antonio Piga Giorgio Pistis Anneli Pouta Ursula Puc Olli Raitakari Susan M Ring Antonietta Robino Daniela Ruggiero Aimo Ruokonen Aude Saint-Pierre Cinzia Sala Andres Salumets Jennifer Sambrook Hein Schepers Carsten Oliver Schmidt Herman H W Silljé Rob Sladek Johannes H Smit John M Starr Jonathan Stephens Patrick Sulem Toshiko Tanaka Unnur Thorsteinsdottir Vinicius Tragante Wiek H van Gilst L Joost van Pelt Dirk J van Veldhuisen Uwe Völker John B Whitfield Gonneke Willemsen Bernhard R Winkelmann Gerald Wirnsberger Ale Algra Francesco Cucca Adamo Pio d'Adamo John Danesh Ian J Deary Anna F Dominiczak Paul Elliott Paolo Fortina Philippe Froguel Paolo Gasparini Andreas Greinacher Stanley L Hazen Marjo-Riitta Jarvelin Kay Tee Khaw Terho Lehtimäki Winfried Maerz Nicholas G Martin Andres Metspalu Braxton D Mitchell Grant W Montgomery Carmel Moore Gerjan Navis Mario Pirastu Peter P Pramstaller Ramiro Ramirez-Solis Eric Schadt James Scott Alan R Shuldiner George Davey Smith J Gustav Smith Harold Snieder Rossella Sorice Tim D Spector Kari Stefansson Michael Stumvoll W H Wilson Tang Daniela Toniolo Anke Tönjes Peter M Visscher Peter Vollenweider Nicholas J Wareham Bruce H R Wolffenbuttel Dorret I Boomsma Jacques S Beckmann George V Dedoussis Panos Deloukas Manuel A Ferreira Serena Sanna Manuela Uda Andrew A Hicks Josef Martin Penninger Christian Gieger Jaspal S Kooner Willem H Ouwehand Nicole Soranzo John C Chambers

Nature 2012 Dec 5;492(7429):369-75. Epub 2012 Dec 5.

Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1038/nature11677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623669PMC
December 2012
131 Reads
132 Citations
42.351 Impact Factor

The fallacy of ratio correction to address confounding factors.

Lab Anim 2012 Jul;46(3):245-52

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1258/la.2012.012003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152922PMC
July 2012
21 Reads
5 Citations
1.120 Impact Factor

Experimental and husbandry procedures as potential modifiers of the results of phenotyping tests.

Physiol Behav 2012 Jul;106(5):602-11

Mouse Genetics Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

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http://dx.doi.org/10.1016/j.physbeh.2012.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391687PMC
July 2012
39 Reads
3 Citations
2.980 Impact Factor

New gene functions in megakaryopoiesis and platelet formation.

Authors:
Christian Gieger Aparna Radhakrishnan Ana Cvejic Weihong Tang Eleonora Porcu Giorgio Pistis Jovana Serbanovic-Canic Ulrich Elling Alison H Goodall Yann Labrune Lorna M Lopez Reedik Mägi Stuart Meacham Yukinori Okada Nicola Pirastu Rossella Sorice Alexander Teumer Katrin Voss Weihua Zhang Ramiro Ramirez-Solis Joshua C Bis David Ellinghaus Martin Gögele Jouke-Jan Hottenga Claudia Langenberg Peter Kovacs Paul F O'Reilly So-Youn Shin Tõnu Esko Jaana Hartiala Stavroula Kanoni Federico Murgia Afshin Parsa Jonathan Stephens Pim van der Harst C Ellen van der Schoot Hooman Allayee Antony Attwood Beverley Balkau François Bastardot Saonli Basu Sebastian E Baumeister Ginevra Biino Lorenzo Bomba Amélie Bonnefond François Cambien John C Chambers Francesco Cucca Pio D'Adamo Gail Davies Rudolf A de Boer Eco J C de Geus Angela Döring Paul Elliott Jeanette Erdmann David M Evans Mario Falchi Wei Feng Aaron R Folsom Ian H Frazer Quince D Gibson Nicole L Glazer Chris Hammond Anna-Liisa Hartikainen Susan R Heckbert Christian Hengstenberg Micha Hersch Thomas Illig Ruth J F Loos Jennifer Jolley Kay Tee Khaw Brigitte Kühnel Marie-Christine Kyrtsonis Vasiliki Lagou Heather Lloyd-Jones Thomas Lumley Massimo Mangino Andrea Maschio Irene Mateo Leach Barbara McKnight Yasin Memari Braxton D Mitchell Grant W Montgomery Yusuke Nakamura Matthias Nauck Gerjan Navis Ute Nöthlings Ilja M Nolte David J Porteous Anneli Pouta Peter P Pramstaller Janne Pullat Susan M Ring Jerome I Rotter Daniela Ruggiero Aimo Ruokonen Cinzia Sala Nilesh J Samani Jennifer Sambrook David Schlessinger Stefan Schreiber Heribert Schunkert James Scott Nicholas L Smith Harold Snieder John M Starr Michael Stumvoll Atsushi Takahashi W H Wilson Tang Kent Taylor Albert Tenesa Swee Lay Thein Anke Tönjes Manuela Uda Sheila Ulivi Dirk J van Veldhuisen Peter M Visscher Uwe Völker H-Erich Wichmann Kerri L Wiggins Gonneke Willemsen Tsun-Po Yang Jing Hua Zhao Paavo Zitting John R Bradley George V Dedoussis Paolo Gasparini Stanley L Hazen Andres Metspalu Mario Pirastu Alan R Shuldiner L Joost van Pelt Jaap-Jan Zwaginga Dorret I Boomsma Ian J Deary Andre Franke Philippe Froguel Santhi K Ganesh Marjo-Riitta Jarvelin Nicholas G Martin Christa Meisinger Bruce M Psaty Timothy D Spector Nicholas J Wareham Jan-Willem N Akkerman Marina Ciullo Panos Deloukas Andreas Greinacher Steve Jupe Naoyuki Kamatani Jyoti Khadake Jaspal S Kooner Josef Penninger Inga Prokopenko Derek Stemple Daniela Toniolo Lorenz Wernisch Serena Sanna Andrew A Hicks Augusto Rendon Manuel A Ferreira Willem H Ouwehand Nicole Soranzo

Nature 2011 Nov 30;480(7376):201-8. Epub 2011 Nov 30.

Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nature10659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335296PMC
November 2011
72 Reads
143 Citations
42.351 Impact Factor

Optimising experimental design for high-throughput phenotyping in mice: a case study.

Mamm Genome 2010 Oct 27;21(9-10):467-76. Epub 2010 Aug 27.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

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http://dx.doi.org/10.1007/s00335-010-9279-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974211PMC
October 2010
16 Reads
4 Citations
3.070 Impact Factor

Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells.

Blood 2006 Jul 8;108(1):116-22. Epub 2005 Dec 8.

Laboratory of Molecular Genetics of Stem cells, Institute for Research in Lmmunology and Cancer (IRIC), Montréal, QC, Canada.

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http://www.bloodjournal.org/content/108/1/116.full.pdf
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2005-06-22
Publisher Site
http://dx.doi.org/10.1182/blood-2005-06-2245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895826PMC
July 2006
8 Reads
17 Citations
10.452 Impact Factor

In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster.

Dev Biol 2003 Dec;264(1):77-90

Center for Extracellular Matrix, Institute of Biosciences and Technology, Texas A&M University, Houston, TX 77030,

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http://dx.doi.org/10.1016/j.ydbio.2003.07.020DOI Listing
December 2003
4 Reads
10 Citations
3.550 Impact Factor

mdmx is a negative regulator of p53 activity in vivo.

Cancer Res 2002 Jun;62(11):3221-5

Lexicon Genetics, Inc., 4000 Research Forest Drive, The Woodlands, TX 77381, USA.

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http://cancerres.aacrjournals.org/content/62/11/3221.full.pd
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June 2002
9 Reads
76 Citations
9.330 Impact Factor