Publications by authors named "Ramin Massoumi"

56Publications

Nemo-Like Kinase in Development and Diseases: Insights from Mouse Studies.

Int J Mol Sci 2020 Dec 2;21(23). Epub 2020 Dec 2.

Department of Laboratory Medicine, Translational Cancer Research, Faculty of Medicine, Lund University, 22381 Lund, Sweden.

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December 2020

High expression of CD34 and α6-integrin contributes to the cancer-initiating cell behaviour in ultraviolet-induced mouse skin squamous cell carcinoma.

J Cancer 2020 30;11(23):6760-6767. Epub 2020 Sep 30.

Department of Laboratory Medicine, Translational Cancer Research, Lund University, Medicon Village, Lund, Sweden.

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September 2020

Gene Expression Signature of Acquired Chemoresistance in Neuroblastoma Cells.

Int J Mol Sci 2020 Sep 16;21(18). Epub 2020 Sep 16.

Department of Laboratory Medicine, Translational Cancer Research, Lund University, Medicon Village, 22381 Lund, Sweden.

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September 2020

Deletion of Nemo-like Kinase in T Cells Reduces Single-Positive CD8 Thymocyte Population.

J Immunol 2020 Oct 24;205(7):1830-1841. Epub 2020 Aug 24.

Molecular Tumor Pathology, Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, 223 81 Lund, Sweden;

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October 2020

Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma.

Sci Rep 2020 07 20;10(1):11997. Epub 2020 Jul 20.

Department of Laboratory Medicine, Translational Cancer Research, Faculty of Medicine, Lund University, 22381, Lund, Sweden.

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July 2020

Preferential Killing of Tetraploid Colon Cancer Cells by Targeting the Mitotic Kinase PLK1.

Cell Physiol Biochem 2020 Apr;54(2):303-320

Department of Laboratory Medicine, Translational Cancer Research, Faculty of Medicine, Lund University, Lund, Sweden,

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April 2020

CYLD, a mechanosensitive deubiquitinase, regulates TGFβ signaling in load-induced bone formation.

Bone 2020 02 9;131:115148. Epub 2019 Nov 9.

Department of Orthopaedic Surgery, University of California San Francisco, 94143, USA; Graduate Program in Oral and Craniofacial Sciences, University of California San Francisco, 94143, USA. Electronic address:

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February 2020

Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis.

Front Pharmacol 2019 26;10:1129. Epub 2019 Sep 26.

Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, CA, United States.

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September 2019

Decreased expression of nemo-like kinase in melanoma is correlated with increased vascularity and metastasis.

Melanoma Res 2019 08;29(4):376-381

Training Center of AIDS prevention and Cure of Hubei Province, Zhongnan Hospital, Wuhan University, Wuhan.

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August 2019

Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1.

Sci Rep 2018 08 7;8(1):11821. Epub 2018 Aug 7.

Department of Laboratory Medicine, Translational Cancer Research, Lund University, Lund, 22381, Sweden.

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August 2018

BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma.

Cell Death Dis 2018 05 1;9(5):458. Epub 2018 May 1.

Department of Laboratory Medicine, Translational Cancer Research, Lund University, Medicon Village, Lund, Sweden.

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May 2018

UVB radiation represses CYLD expression in melanocytes.

Oncol Lett 2017 Dec 3;14(6):7262-7268. Epub 2017 Oct 3.

Emil-Fischer-Center, Institute of Biochemistry, Friedrich Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.

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December 2017

NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling.

Mol Biol Cell 2017 01 30;28(2):346-355. Epub 2016 Nov 30.

Department of Laboratory Medicine, Translational Cancer Research, Lund University, Lund 22381, Sweden

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January 2017

CYLD and SUMO in neuroblastoma therapy.

Oncoscience 2016 29;3(1):3-4. Epub 2016 Jan 29.

Department of Laboratory Medicine, Translational Cancer Research, Division of Molecular Tumour Pathology, Lund University, Sweden.

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March 2016

Putative role of SUMOylation in controlling the activity of deubiquitinating enzymes in cancer.

Future Oncol 2016 Feb 18;12(4):565-74. Epub 2016 Jan 18.

Department of Laboratory Medicine, Medicon Village, Lund University, 22381 Lund, Sweden.

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February 2016

Cylindromatosis--A Protective Molecule against Liver Diseases.

Med Res Rev 2016 Mar 13;36(2):342-59. Epub 2016 Jan 13.

Department of Laboratory Medicine, Medicon Village, Lund University, 22381, Lund, Sweden.

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March 2016

Early diagnostic value of Bcl-3 localization in colorectal cancer.

BMC Cancer 2015 May 1;15:341. Epub 2015 May 1.

Department of Laboratory Medicine, Translational Cancer Research, Division of Molecular Tumour Pathology, Lund University, Medicon Village, Building 404:A3, 223 83, Lund, Sweden.

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May 2015

Multifaceted role of the ubiquitin ligase Itch in immune regulation.

Immunol Cell Biol 2015 May-Jun;93(5):452-60. Epub 2015 Jan 13.

Department of Laboratory Medicine, Lund University, Medicon Village, Lund, Sweden.

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February 2016

Deubiquitination of γ-tubulin by BAP1 prevents chromosome instability in breast cancer cells.

Cancer Res 2014 Nov 16;74(22):6499-508. Epub 2014 Sep 16.

Department of Laboratory Medicine, Translational Cancer Research, Lund University, Medicon Village, Lund, Sweden.

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November 2014

Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells.

PLoS One 2014 9;9(5):e96506. Epub 2014 May 9.

Translational Cancer Research, Molecular Tumor Pathology, Department of Laboratory Medicine, Lund University, Lund, Sweden.

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October 2015

Cylindromatosis gene CYLD regulates hepatocyte growth factor expression in hepatic stellate cells through interaction with histone deacetylase 7.

Hepatology 2014 Sep 17;60(3):1066-81. Epub 2014 Jul 17.

Department of Laboratory Medicine, Medicon Village, Lund University, Lund, Sweden.

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September 2014

CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma.

Carcinogenesis 2014 Feb 8;35(2):461-8. Epub 2013 Oct 8.

Department of Laboratory Medicine, Skåne University Hospital, Lund University, Malmö SE-20502, Sweden.

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February 2014

CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production.

PLoS Pathog 2013 27;9(6):e1003455. Epub 2013 Jun 27.

Institute of Medical Microbiology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

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January 2014

Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer.

J Skin Cancer 2011 17;2011:614097. Epub 2011 Dec 17.

Molecular Tumor Pathology, Department of Laboratory Medicine, Lund University, Skåne University Hospital, 205 02 Malmö, Sweden.

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August 2012

The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.

Nat Immunol 2011 Nov 6;12(12):1176-83. Epub 2011 Nov 6.

Karmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA.

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November 2011

Caspase 8 inhibits programmed necrosis by processing CYLD.

Nat Cell Biol 2011 Oct 30;13(12):1437-42. Epub 2011 Oct 30.

Immunology Institute, Mount Sinai School of Medicine, New York, New York 10029, USA.

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October 2011

Serum response factor controls CYLD expression via MAPK signaling pathway.

PLoS One 2011 May 5;6(5):e19613. Epub 2011 May 5.

Department of Laboratory Medicine, Lund University, UMAS, Malmö, Sweden.

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May 2011

CYLD: a deubiquitination enzyme with multiple roles in cancer.

Authors:
Ramin Massoumi

Future Oncol 2011 Feb;7(2):285-97

Department of Laboratory Medicine, Molecular Tumor Pathology, Lund University, Malmö, Sweden.

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February 2011

Mutated cylindromatosis gene affects the functional state of dendritic cells.

Eur J Immunol 2010 Oct;40(10):2848-57

Clinical Research Unit Allergology, Department of Dermatology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

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October 2010

Ubiquitin chain cleavage: CYLD at work.

Authors:
Ramin Massoumi

Trends Biochem Sci 2010 Jul 26;35(7):392-9. Epub 2010 Mar 26.

Department of Laboratory Medicine, Clinical Research Center, Lund University, SE-205 Malmö, Sweden.

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July 2010

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.

EMBO J 2010 Jan 5;29(1):131-44. Epub 2009 Nov 5.

Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany.

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January 2010

The central role of Bcl-3 in atopic dermatitis.

Authors:
Ramin Massoumi

J Invest Dermatol 2009 Sep;129(9):2088-90

Department of Laboratory Medicine, Lund University, Malmö University Hospital, Malmö, Sweden.

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September 2009

CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration.

PLoS One 2009 Jul 28;4(7):e6371. Epub 2009 Jul 28.

Cell and Experimental Pathology, Department of Laboratory Medicine, Lund University, Clinical Research Centre, Malmö University Hospital (UMAS), Malmö, Sweden.

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July 2009

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma.

J Exp Med 2009 Jan 5;206(1):221-32. Epub 2009 Jan 5.

Department of Molecular Medicine, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

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January 2009

Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activation.

Cancer Cell 2008 Nov;14(5):394-407

Department of Medicine, VA Greater Los Angeles Healthcare System-West Los Angeles, Los Angeles, CA 90095, USA.

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November 2008

Leukotriene D(4) induces AP-1 but not NFkappaB signaling in intestinal epithelial cells.

Prostaglandins Other Lipid Mediat 2008 Mar 12;85(3-4):100-6. Epub 2007 Nov 12.

Cell and Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmö University Hospital, Malmö, Sweden.

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March 2008

Cylindromatosis and the CYLD gene: new lessons on the molecular principles of epithelial growth control.

Bioessays 2007 Dec;29(12):1203-14

Department of Laboratory Medicine, Clinical Research Center, Lund University, Malmö University Hospital, Malmö, Sweden.

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December 2007

The role of leukotriene receptor signaling in inflammation and cancer.

ScientificWorldJournal 2007 Sep 1;7:1413-21. Epub 2007 Sep 1.

Cell and Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmo University Hospital, Malmo, Sweden.

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September 2007

Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells.

J Cell Physiol 2006 Dec;209(3):950-8

Cell and Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmö University Hospital, SE-205 02 Malmö, Sweden.

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December 2006

Reduced expression of CYLD in human colon and hepatocellular carcinomas.

Carcinogenesis 2007 Jan 13;28(1):21-7. Epub 2006 Jun 13.

Department of Internal Medicine I, University Regensburg, 93053 Regensburg, Germany.

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January 2007

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.

Cell 2006 May;125(4):665-77

Department of Molecular Medicine, Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany.

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May 2006

Leukotriene D4 activates distinct G-proteins in intestinal epithelial cells to regulate stress fibre formation and to generate intracellular Ca2+ mobilisation and ERK1/2 activation.

Exp Cell Res 2005 Jan;302(1):31-9

Department of Laboratory Medicine, Experimental Pathology, Lund University, Malmö University Hospital, SE-205 02 Malmö, Sweden.

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January 2005

Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin.

Exp Cell Res 2003 Oct;289(2):342-51

Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmö University Hospital, SE-205 02 Malmö, Sweden.

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October 2003

The leukotriene receptor CysLT1 and 5-lipoxygenase are upregulated in colon cancer.

Adv Exp Med Biol 2003 ;525:201-4

Department of Laboratory Medicine, Lund University, Malmö University Hospital, Sweden.

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August 2003

Leukotriene D(4) induces stress-fibre formation in intestinal epithelial cells via activation of RhoA and PKCdelta.

J Cell Sci 2002 Sep;115(Pt 17):3509-15

Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmö University Hospital, SE-205 02 Malmö, Sweden.

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September 2002

Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells.

Biochem J 2002 Jul;365(Pt 1):157-63

Division of Experimental Pathology, Department of Laboratory Medicine, Lund University, University Hospital Malmö, SE-205 02 Malmö, Sweden.

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July 2002