Publications by authors named "Ramesh K Ganju"

64Publications

Cannabinoid Signaling in Cancer.

Adv Exp Med Biol 2019 ;1162:51-61

Department of Pathology, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1007/978-3-030-21737-2_4DOI Listing
September 2019

Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I.

J Mol Biol 2019 01 17;431(2):368-390. Epub 2018 Nov 17.

Biomedical Engineering Department, the Ohio State University Columbus, OH 43210, USA; Biophysics Program, the Ohio State University, Columbus, OH 43210, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222836183123
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http://dx.doi.org/10.1016/j.jmb.2018.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346271PMC
January 2019

Enhanced peripheral dopamine impairs post-ischemic healing by suppressing angiotensin receptor type 1 expression in endothelial cells and inhibiting angiogenesis.

Angiogenesis 2017 Feb 16;20(1):97-107. Epub 2016 Nov 16.

Department of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1007/s10456-016-9531-8DOI Listing
February 2017

TRPV2 is a novel biomarker and therapeutic target in triple negative breast cancer.

Oncotarget 2018 Sep 27;9(71):33459-33470. Epub 2016 May 27.

Department of Pathology, Wexner Medical Center, Ohio State University (OSU), Columbus, OH, USA.

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http://www.oncotarget.com/fulltext/9663
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http://dx.doi.org/10.18632/oncotarget.9663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173360PMC
September 2018

Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer.

Oncotarget 2017 May;8(18):29668-29678

Department of Pathology and The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, Columbus, OH, USA.

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http://dx.doi.org/10.18632/oncotarget.9408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444694PMC
May 2017

RAGE: A novel target for breast cancer growth and metastasis.

Oncoscience 2016 3;3(2):52-3. Epub 2016 Mar 3.

Department of Pathology, The Ohio State University, Columbus, OH, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789569PMC
http://dx.doi.org/10.18632/oncoscience.294DOI Listing
March 2016

Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis.

Mol Oncol 2016 Feb 28;10(2):272-81. Epub 2015 Oct 28.

Department of Pathology, The Ohio State University Wexner Medical Center, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739522PMC
February 2016

Cannabinoid receptor-2 agonist inhibits macrophage induced EMT in non-small cell lung cancer by downregulation of EGFR pathway.

Mol Carcinog 2016 12 6;55(12):2063-2076. Epub 2016 Jan 6.

Department of Pathology, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1002/mc.22451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063844PMC
December 2016

Erratum to: miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer.

Mol Cancer 2015 Nov 16;14(1):195. Epub 2015 Nov 16.

Department of Pathology, The Ohio State University Wexner Medical Center, 840 BRT, 460 W 12th Ave, Columbus, 43210, OH, USA.

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http://dx.doi.org/10.1186/s12943-015-0451-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647705PMC
November 2015

Non-contact method for directing electrotaxis.

Sci Rep 2015 Jun 9;5:11005. Epub 2015 Jun 9.

Department of Mechanical &Aerospace Engineering, The Ohio State University, Columbus, Ohio, U.S.A.

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http://dx.doi.org/10.1038/srep11005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460731PMC
June 2015

Conditioning solid tumor microenvironment through inflammatory chemokines and S100 family proteins.

Cancer Lett 2015 Aug 8;365(1):11-22. Epub 2015 May 8.

Department of Pathology, Comprehensive Cancer Center, The Ohio State Medical Center, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.canlet.2015.05.002DOI Listing
August 2015

Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: novel anti-tumor mechanisms of Cannabidiol in breast cancer.

Mol Oncol 2015 Apr 19;9(4):906-19. Epub 2015 Jan 19.

Department of Pathology, The Ohio State University, Wexner Medical Center, 43210, USA; The Comprehensive Cancer Center, The Ohio State University, Wexner Medical Center, 43210, USA. Electronic address:

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https://www.alchimiaweb.com/blogfr/wp-content/uploads/2015/0
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http://linkinghub.elsevier.com/retrieve/pii/S157478911400295
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http://dx.doi.org/10.1016/j.molonc.2014.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387115PMC
April 2015

miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer.

Mol Cancer 2015 Jan 27;14:11. Epub 2015 Jan 27.

Department of Pathology, The Ohio State University Wexner Medical Center, 840 BRT, 460W 12th Ave, Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1186/s12943-014-0275-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314775PMC
January 2015

Cannabinoids as therapeutic agents in cancer: current status and future implications.

Oncotarget 2014 Aug;5(15):5852-72

Department of Pathology, The Ohio State University, Columbus, Ohio, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171598PMC
http://dx.doi.org/10.18632/oncotarget.2233DOI Listing
August 2014

CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model.

Immunology 2014 Sep;143(1):109-19

Department of Pathology, The Ohio State University Medical Center, Columbus, OH, USA; Department of Oral Biology, The Ohio State University College of Dentistry, Columbus, OH, USA.

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http://dx.doi.org/10.1111/imm.12293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137960PMC
September 2014

Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.

J Immunol 2014 Jan 22;192(1):385-93. Epub 2013 Nov 22.

Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210.

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http://dx.doi.org/10.4049/jimmunol.1302021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908786PMC
January 2014

Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.

Hepatology 2014 Feb 20;59(2):555-66. Epub 2013 Dec 20.

Department of Molecular and Cellular Biochemistry, Ohio State University, Columbus, OH; Molecular, Cellular and Developmental Biology Program, Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1002/hep.26712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199239PMC
February 2014

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

Retrovirology 2013 Jan 7;10. Epub 2013 Jan 7.

Department of Pathology, Ohio State University Wexner Medical Center, 460 W 12th Avenue, 810 Biological Research Tower, Columbus, OH 43210, USA.

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http://retrovirology.biomedcentral.com/articles/10.1186/1742
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http://dx.doi.org/10.1186/1742-4690-10-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562244PMC
January 2013

The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells.

J Immunol 2012 Mar 8;188(6):2769-77. Epub 2012 Feb 8.

Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.4049/jimmunol.1102106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908818PMC
March 2012

Tumor-suppressive effects of psoriasin (S100A7) are mediated through the β-catenin/T cell factor 4 protein pathway in estrogen receptor-positive breast cancer cells.

J Biol Chem 2011 Dec 20;286(52):44845-54. Epub 2011 Oct 20.

Department of Pathology, The Ohio State University Medical and Comprehensive Cancer Center, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1074/jbc.M111.225466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248020PMC
December 2011

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.

PLoS One 2011 7;6(9):e23901. Epub 2011 Sep 7.

Department of Pathology and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023901PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168464PMC
February 2012

A novel role for Slit2/Robo1 axis in modulating HIV-1 replication in T cells.

AIDS 2011 Nov;25(17):2105-11

Department of Pathology, Ohio State University Medical Center, Columbus, 43210, USA.

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https://insights.ovid.com/crossref?an=00002030-201111130-000
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http://dx.doi.org/10.1097/QAD.0b013e32834bab86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123625PMC
November 2011

Cdc25A regulates matrix metalloprotease 1 through Foxo1 and mediates metastasis of breast cancer cells.

Mol Cell Biol 2011 Aug 13;31(16):3457-71. Epub 2011 Jun 13.

Department of Pathology, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1128/MCB.05523-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147788PMC
August 2011

Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition.

J Cell Biochem 2011 Mar;112(3):804-17

Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://doi.wiley.com/10.1002/jcb.22961
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http://dx.doi.org/10.1002/jcb.22961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110974PMC
March 2011

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis.

Cancer Prev Res (Phila) 2011 Jan 19;4(1):65-75. Epub 2010 Nov 19.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025486PMC
January 2011

LPS-induced MCP-1 expression in human microvascular endothelial cells is mediated by the tyrosine kinase, Pyk2 via the p38 MAPK/NF-kappaB-dependent pathway.

Mol Immunol 2009 Feb 26;46(5):962-8. Epub 2008 Oct 26.

Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.molimm.2008.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680789PMC
February 2009

Medicinal plants and cancer chemoprevention.

Curr Drug Metab 2008 Sep;9(7):581-91

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160808PMC
http://dx.doi.org/10.2174/138920008785821657DOI Listing
September 2008

Underlying pathophysiology of HCV infection in HIV-positive drug users.

J Addict Dis 2008 ;27(2):75-82

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720610PMC
http://dx.doi.org/10.1300/J069v27n02_09DOI Listing
September 2008

Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.

J Biol Chem 2008 Sep 8;283(39):26624-33. Epub 2008 Jul 8.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M800679200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546548PMC
September 2008

Phytoestrogens and breast cancer prevention: possible mechanisms of action.

Environ Health Perspect 2008 Apr;116(4):426-33

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1289/ehp.10538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291001PMC
April 2008

The tyrosine kinase Pyk2 mediates lipopolysaccharide-induced IL-8 expression in human endothelial cells.

J Immunol 2008 Apr;180(8):5636-44

Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117313PMC
http://dx.doi.org/10.4049/jimmunol.180.8.5636DOI Listing
April 2008

S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation.

PLoS One 2008 Mar 5;3(3):e1741. Epub 2008 Mar 5.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001741PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254193PMC
March 2008

Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells.

J Leukoc Biol 2007 Sep 12;82(3):465-76. Epub 2007 Jun 12.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1189/jlb.1106678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2286829PMC
September 2007

Signal transducer and activator of transcription factor 1 mediates apoptosis induced by hepatitis C virus and HIV envelope proteins in hepatocytes.

J Infect Dis 2006 Sep 18;194(5):670-81. Epub 2006 Jul 18.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, MA 02115, USA.

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http://dx.doi.org/10.1086/505708DOI Listing
September 2006

Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis.

Int Immunol 2006 Aug 23;18(8):1315-25. Epub 2006 Jun 23.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Room 343, Harvard Medical School, 4 Blackfan Circle, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/intimm/dxl064DOI Listing
August 2006

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

J Biol Chem 2006 May 7;281(18):12289-99. Epub 2006 Mar 7.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M511786200DOI Listing
May 2006

Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes.

Mol Immunol 2006 Jul 28;43(14):2169-79. Epub 2006 Feb 28.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016158900600016
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http://dx.doi.org/10.1016/j.molimm.2006.01.005DOI Listing
July 2006

Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells.

J Gen Virol 2005 Dec;86(Pt 12):3291-3301

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 4 Blackfan Circle, 3rd Floor, Boston, MA 02115, USA.

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http://dx.doi.org/10.1099/vir.0.81056-0DOI Listing
December 2005

Molecular mechanism of hepatic injury in coinfection with hepatitis C virus and HIV.

Clin Infect Dis 2005 Jul;41 Suppl 1:S32-7

Division of Experimental Medicine and Infectious Disease, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, MA 02115, USA.

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http://dx.doi.org/10.1086/429493DOI Listing
July 2005

Alpha-chemokine-mediated signal transduction in human Kaposi's sarcoma spindle cells.

Biochim Biophys Acta 2004 May;1691(2-3):129-39

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, 4 Blackfan Circle, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2004.01.002DOI Listing
May 2004

Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells.

J Biol Chem 2004 Mar 26;279(10):9115-24. Epub 2003 Nov 26.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M308083200DOI Listing
March 2004

Hepatitis C and human immunodeficiency virus envelope proteins cooperatively induce hepatocytic apoptosis via an innocent bystander mechanism.

J Infect Dis 2003 Oct 30;188(8):1192-204. Epub 2003 Sep 30.

Divisions of Experimental Medicine and Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1086/378643DOI Listing
October 2003

Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes.

J Biol Chem 2003 Sep 24;278(37):35755-66. Epub 2003 Jun 24.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M302889200DOI Listing
September 2003

Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.

J Biol Chem 2003 Mar 8;278(11):9536-43. Epub 2003 Jan 8.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M211803200DOI Listing
March 2003

Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor.

J Immunol 2002 Jun;168(11):5860-6

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4049/jimmunol.168.11.5860DOI Listing
June 2002

CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway.

J Biol Chem 2002 May 4;277(20):18111-7. Epub 2002 Mar 4.

Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M200750200DOI Listing
May 2002