Raman Venkataramanan

Raman Venkataramanan

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Raman Venkataramanan

Publications by authors named "Raman Venkataramanan"

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Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis.

Biomaterials 2019 Jul 26;210:25-40. Epub 2019 Apr 26.

Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01429612193024
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http://dx.doi.org/10.1016/j.biomaterials.2019.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538300PMC
July 2019

Reply.

Am J Obstet Gynecol 2019 Jun 18;220(6):608-609. Epub 2019 Feb 18.

Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal-Fetal Medicine, Magee-Womens Hospital of the University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2019.02.031DOI Listing
June 2019

Defining the clinical response to 17-alpha hydroxyprogesterone caproate.

Am J Obstet Gynecol 2018 12 29;219(6):623-625. Epub 2018 Aug 29.

Department of Clinical Analytics, University of Pittsburgh Medical Center, Pittsburgh, PA 15213.

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https://linkinghub.elsevier.com/retrieve/pii/S00029378183071
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http://dx.doi.org/10.1016/j.ajog.2018.08.040DOI Listing
December 2018

Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients.

Antimicrob Agents Chemother 2018 12 26;62(12). Epub 2018 Nov 26.

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

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http://aac.asm.org/lookup/doi/10.1128/AAC.01643-18
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http://dx.doi.org/10.1128/AAC.01643-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256763PMC
December 2018

Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections.

J Virol 2018 10 12;92(19). Epub 2018 Sep 12.

Department of Microbiology and Immunology, Programs in Global Oncology and Virology, Lineberger Comprehensive Cancer Center and Center for AIDS Research, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1128/JVI.01138-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146794PMC
October 2018

Novel glucosylceramide synthase inhibitor based prodrug copolymer micelles for delivery of anticancer agents.

J Control Release 2018 Oct 14;288:212-226. Epub 2018 Sep 14.

Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2018.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177216PMC
October 2018

Gestational changes in buprenorphine exposure: A physiologically-based pharmacokinetic analysis.

Br J Clin Pharmacol 2018 09 21;84(9):2075-2087. Epub 2018 Jun 21.

University of Pittsburgh, Department of Pharmaceutical Sciences, School of Pharmacy, Pittsburgh, PA.

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http://doi.wiley.com/10.1111/bcp.13642
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http://dx.doi.org/10.1111/bcp.13642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089832PMC
September 2018

Impact of Obesity on the Rate of Recurrent Spontaneous Preterm Birth in Women Treated with 17-alpha Hydroxyprogesterone Caproate.

Am J Perinatol 2018 07 2;35(9):809-814. Epub 2018 Jan 2.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1617453
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http://dx.doi.org/10.1055/s-0037-1617453DOI Listing
July 2018

Increasing tacrolimus time-in-therapeutic range is associated with superior one-year outcomes in lung transplant recipients.

Am J Transplant 2018 Jun 6;18(6):1527-1533. Epub 2018 Apr 6.

Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/ajt.14723DOI Listing
June 2018

The Role of Preterm Birth in the Association Between Opioid Maintenance Therapy and Neonatal Abstinence Syndrome.

Paediatr Perinat Epidemiol 2018 03 26;32(2):213-222. Epub 2018 Jan 26.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1111/ppe.12443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902412PMC
March 2018

Newly Emerging Drugs of Abuse and Their Detection Methods: An ACLPS Critical Review.

Am J Clin Pathol 2018 Jan;149(2):105-116

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1093/ajcp/aqx138DOI Listing
January 2018

Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver.

Biochem Pharmacol 2017 12 6;145:218-225. Epub 2017 Sep 6.

Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681379PMC
December 2017

An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat.

EBioMedicine 2017 Dec 24;26:47-59. Epub 2017 Nov 24.

Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, United States; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832622PMC
December 2017

A physiologically based pharmacokinetic modelling approach to predict buprenorphine pharmacokinetics following intravenous and sublingual administration.

Br J Clin Pharmacol 2017 Nov 22;83(11):2458-2473. Epub 2017 Aug 22.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/bcp.13368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651326PMC
November 2017

Synergistic immunosuppression and unintended consequences.

Pediatr Transplant 2017 11 21;21(7). Epub 2017 Aug 21.

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/petr.13047DOI Listing
November 2017

An evidence-based recommendation to increase the dosing frequency of buprenorphine during pregnancy.

Am J Obstet Gynecol 2017 10 29;217(4):459.e1-459.e6. Epub 2017 Jun 29.

Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2017.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614874PMC
October 2017

Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy.

J Control Release 2017 07 12;258:43-55. Epub 2017 May 12.

Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525542PMC
July 2017

Effect of aerosolized antipseudomonals on Pseudomonas positivity and bronchiolitis obliterans syndrome after lung transplantation.

Transpl Infect Dis 2017 Jun 17;19(3). Epub 2017 Apr 17.

Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/tid.12688DOI Listing
June 2017

Low vitamin D exposure is associated with higher risk of infection in renal transplant recipients.

Clin Transplant 2017 05 4;31(5). Epub 2017 Apr 4.

Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/ctr.12955DOI Listing
May 2017

Delayed villous maturation in term placentas exposed to opioid maintenance therapy: a retrospective cohort study.

Am J Obstet Gynecol 2017 04 23;216(4):418.e1-418.e5. Epub 2016 Dec 23.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2016.12.016DOI Listing
April 2017

Drug Metabolism in the Liver.

Clin Liver Dis 2017 02 15;21(1):1-20. Epub 2016 Oct 15.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 718 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA; Department of Pathology, University of Pittsburgh Medical Center, Thomas Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2016.08.001DOI Listing
February 2017

Drug Metabolism, Drug Interactions, and Drug-Induced Liver Injury in Living Donor Liver Transplant Patients.

Clin Liver Dis 2017 02;21(1):181-196

Thomas Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 718 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10893261163007
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http://dx.doi.org/10.1016/j.cld.2016.08.011DOI Listing
February 2017

Mechanisms of Drug-Induced Hepatotoxicity.

Clin Liver Dis 2017 02;21(1):35-54

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 718 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2016.08.002DOI Listing
February 2017

Janus kinase inhibition for immunosuppression in solid organ transplantation: Is there a role in complex immunologic challenges?

Hum Immunol 2017 Feb 18;78(2):64-71. Epub 2016 Dec 18.

Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States; Division of Pulmonary, Allergy, and Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

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http://dx.doi.org/10.1016/j.humimm.2016.12.005DOI Listing
February 2017

Single Implantable FK506 Disk Prevents Rejection in Vascularized Composite Allotransplantation.

Plast Reconstr Surg 2017 Feb;139(2):403e-414e

Pittsburgh, Pa. From the Departments of Plastic Surgery, Bioengineering, and Pharmaceutical Science, School of Pharmacy, and the McGowan Institute for Regenerative Medicine, University of Pittsburgh Medical Center.

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http://dx.doi.org/10.1097/PRS.0000000000002951DOI Listing
February 2017

Nausea and vomiting of pregnancy - What's new?

Auton Neurosci 2017 01 13;202:62-72. Epub 2016 May 13.

Department of Obstetrics, Gynecology and Reproductive Sciences Magee Womens Hospital, 300 Halket St., Pittsburgh, PA 15213-3180, United States; School of Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, 300 Halket Street, Pittsburgh, PA 15213, United States. Electronic address:

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http://dx.doi.org/10.1016/j.autneu.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107351PMC
January 2017

Dose-adjusted plasma concentrations of sublingual buprenorphine are lower during than after pregnancy.

Am J Obstet Gynecol 2017 Jan 26;216(1):64.e1-64.e7. Epub 2016 Sep 26.

Divisions of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2016.09.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245872PMC
January 2017

Polymorphisms in CYP1A1 and CYP3A5 Genes Contribute to the Variability in Granisetron Clearance and Exposure in Pregnant Women with Nausea and Vomiting.

Pharmacotherapy 2016 12 5;36(12):1238-1244. Epub 2016 Dec 5.

Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/phar.1860DOI Listing
December 2016

Route of administration and formulation dependent pharmacokinetics of 17-hydroxyprogesterone caproate in rats.

Xenobiotica 2016 7;46(2):169-74. Epub 2015 Jul 7.

a Department of Pharmaceutical Sciences , School of Pharmacy, University of Pittsburgh , Pittsburgh , PA , USA .

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http://dx.doi.org/10.3109/00498254.2015.1057547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809632PMC
November 2016

An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy.

Nat Commun 2016 11 7;7:13443. Epub 2016 Nov 7.

Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1038/ncomms13443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103075PMC
November 2016

Pharmacokinetics of drugs in adult living donor liver transplant patients: regulatory factors and observations based on studies in animals and humans.

Expert Opin Drug Metab Toxicol 2016 6;12(3):231-43. Epub 2016 Feb 6.

a Department of Pharmaceutical Sciences, School of Pharmacy , University of Pittsburgh , Pittsburgh , PA , USA.

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http://dx.doi.org/10.1517/17425255.2016.1139575DOI Listing
October 2016

Population pharmacokinetics of 17α-hydroxyprogesterone caproate in singleton gestation.

Br J Clin Pharmacol 2016 10 13;82(4):1084-93. Epub 2016 Jul 13.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/bcp.12990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137834PMC
October 2016

A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel.

Acta Biomater 2016 10 12;43:282-291. Epub 2016 Jul 12.

Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2016.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012958PMC
October 2016

Ondansetron Exposure Changes in a Pregnant Woman.

Pharmacotherapy 2016 09 25;36(9):e139-41. Epub 2016 Jul 25.

Department of Pharmaceutical Science, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/phar.1796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738660PMC
September 2016

Pharmacodynamics of transdermal granisetron in women with nausea and vomiting of pregnancy.

Am J Obstet Gynecol 2016 07 23;215(1):93.e1-4. Epub 2016 Jan 23.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA; School of Pharmacy, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2016.01.163DOI Listing
July 2016

Pharmacokinetics of Posaconazole Suspension in Lung Transplant Patients with and without Cystic Fibrosis.

Antimicrob Agents Chemother 2016 06 23;60(6):3558-62. Epub 2016 May 23.

Department of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1128/AAC.00424-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879430PMC
June 2016

Ondansetron Use in Pregnancy.

Obstet Gynecol 2016 05;127(5):873-7

Department of Epidemiology, Graduate School of Public Health, the Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Magee Womens Hospital of the University of Pittsburgh Medical Center, the Department of Pharmaceutical Sciences, School of Pharmacy, and the Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/AOG.0000000000001375DOI Listing
May 2016

A Pilot Study of Continuous Infusion of Mycophenolate Mofetil for Prophylaxis of Graft-versus-Host-Disease in Pediatric Patients.

Biol Blood Marrow Transplant 2016 Apr 29;22(4):682-689. Epub 2015 Dec 29.

Department of Pharmaceutical Science, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Thomas Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2015.12.013DOI Listing
April 2016

Transition from brand to generic tacrolimus is associated with a decrease in trough blood concentration in pediatric heart transplant recipients.

Pediatr Transplant 2015 Dec 25;19(8):911-7. Epub 2015 Oct 25.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/petr.12608DOI Listing
December 2015

Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation.

Br J Clin Pharmacol 2015 Nov 19;80(5):1097-108. Epub 2015 Sep 19.

Department of Pharmaceutical Sciences, School of Pharmacy, Pittsburgh, PA.

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http://dx.doi.org/10.1111/bcp.12723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631182PMC
November 2015

Pharmacokinetics of drugs in pregnancy.

Semin Perinatol 2015 Nov;39(7):512-9

Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Magee Womens Hospital of UPMC, University of Pittsburgh, 300 Halket St, Pittsburgh, PA 15213.

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http://dx.doi.org/10.1053/j.semperi.2015.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809631PMC
November 2015

Pharmacokinetics of cefazolin prophylaxis in obese gravidae at time of cesarean delivery.

Am J Obstet Gynecol 2015 Oct 20;213(4):541.e1-7. Epub 2015 Jun 20.

Division of Maternal-Fetal Medicine, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA; Magee-Womens Research Institute, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2015.06.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586370PMC
October 2015

Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy.

Biomaterials 2015 Oct 15;67:104-14. Epub 2015 Jul 15.

Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.07.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550547PMC
October 2015

Rapid and sensitive assessment of human hepatocyte functions.

Cell Transplant 2014 4;23(12):1545-56. Epub 2014 Apr 4.

Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Stockholm, Sweden.

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http://journals.sagepub.com/doi/full/10.3727/096368914X68006
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http://dx.doi.org/10.3727/096368914X680064DOI Listing
September 2015

Prevention of preterm delivery with 17-hydroxyprogesterone caproate: pharmacologic considerations.

Semin Perinatol 2014 Dec 23;38(8):516-22. Epub 2014 Sep 23.

Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1053/j.semperi.2014.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253874PMC
December 2014

Basic obstetric pharmacology.

Semin Perinatol 2014 Dec 1;38(8):475-86. Epub 2014 Oct 1.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 718 Salk Hall, 3501 Terrace St, Pittsburgh, PA 15261; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA; Thomas Starzl Transplantation Institute, Pittsburgh, PA; McGovern Institute for Regenerative Medicine, Pittsburgh, PA; Magee Womens Research Institute, Pittsburgh, PA. Electronic address:

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http://dx.doi.org/10.1053/j.semperi.2014.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771662PMC
December 2014

Oseltamivir for influenza in pregnancy.

Semin Perinatol 2014 Dec 1;38(8):503-7. Epub 2014 Oct 1.

Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, 300 Halket St, Pittsburgh, PA 15213.

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http://dx.doi.org/10.1053/j.semperi.2014.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745365PMC
December 2014

An improved D-α-tocopherol-based nanocarrier for targeted delivery of doxorubicin with reversal of multidrug resistance.

J Control Release 2014 Dec 24;196:272-86. Epub 2014 Oct 24.

Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2014.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267990PMC
December 2014

Potential interactions between HIV drugs, ritonavir and efavirenz and anticancer drug, nilotinib--a study in primary cultures of human hepatocytes that is applicable to HIV patients with cancer.

J Clin Pharmacol 2014 Nov 27;54(11):1272-9. Epub 2014 May 27.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/jcph.333DOI Listing
November 2014

Fmoc-conjugated PEG-vitamin E2 micelles for tumor-targeted delivery of paclitaxel: enhanced drug-carrier interaction and loading capacity.

AAPS J 2014 Nov 6;16(6):1282-91. Epub 2014 Sep 6.

Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, 639 Salk Hall, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1208/s12248-014-9651-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389742PMC
November 2014

Targeted delivery of Doxorubicin by folic acid-decorated dual functional nanocarrier.

Mol Pharm 2014 Nov 29;11(11):4164-78. Epub 2014 Sep 29.

Center for Pharmacogenetics, ‡Department of Pharmaceutical Sciences, School of Pharmacy, and §University of Pittsburgh Cancer Institute, University of Pittsburgh , Pittsburgh, Pennsylvania 15261, United States.

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http://dx.doi.org/10.1021/mp500389vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224520PMC
November 2014

Targeted delivery of anticancer agents via a dual function nanocarrier with an interfacial drug-interactive motif.

Biomacromolecules 2014 Nov 28;15(11):4326-35. Epub 2014 Oct 28.

Center for Pharmacogenetics; ‡Department of Pharmaceutical Sciences, School of Pharmacy; and §University of Pittsburgh Cancer Institute, University of Pittsburgh , Pittsburgh, Pennsylvania 15261, United States.

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http://dx.doi.org/10.1021/bm501339jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229023PMC
November 2014

Impact of 17-alpha-hydroxyprogesterone caproate on cytochrome P450s in primary cultures of human hepatocytes.

Am J Obstet Gynecol 2014 Oct 26;211(4):412.e1-6. Epub 2014 Mar 26.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA; Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA; Magee Womens Research Institute, Pittsburgh, PA; Thomas Starzl Transplantation Institute, Pittsburgh, PA; McGovern Institute for Regenerative Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2014.03.048DOI Listing
October 2014

A microphysiological system model of therapy for liver micrometastases.

Exp Biol Med (Maywood) 2014 Sep 12;239(9):1170-9. Epub 2014 May 12.

Departments of Pathology, Cell Biology, Pharmaceutical Sciences, and Bioengineering, and the McGowan Institute for Regenerative Medicine, University of Pittsburgh and Pittsburgh VA Health System, Pittsburgh, PA 15213, USA

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http://dx.doi.org/10.1177/1535370214532596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574864PMC
September 2014

A PEG-Fmoc conjugate as a nanocarrier for paclitaxel.

Biomaterials 2014 Aug 22;35(25):7146-56. Epub 2014 May 22.

Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.04.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102141PMC
August 2014

PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel.

Mol Pharm 2014 Aug 11;11(8):2807-14. Epub 2014 Jul 11.

Center for Pharmacogenetics, ‡Department of Pharmaceutical Sciences, School of Pharmacy, and §University of Pittsburgh Cancer Institute, University of Pittsburgh , Pittsburgh, Pennsylvania 15261, United States.

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http://dx.doi.org/10.1021/mp500181xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123940PMC
August 2014

Phototoxic dermatoses in pediatric BMT patients receiving voriconazole.

Pediatr Blood Cancer 2014 Jul 11;61(7):1325-8. Epub 2014 Mar 11.

Division of Blood and Marrow Transplantation and Cellular Therapies, Children's Hospital of Pittsburgh of UPMC, Pennsylvania; Departments of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://doi.wiley.com/10.1002/pbc.24897
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http://dx.doi.org/10.1002/pbc.24897DOI Listing
July 2014

Stability of hydroxyprogesterone caproate alone and in a compounded pharmaceutical product.

Am J Health Syst Pharm 2014 Jul;71(13):1120-7

Yang Zhao, Ph.D., is Research Associate, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA. Joseph Bettinger, B.S.Pharm., is Compounding Specialist, Hiebers Pharmacy, Pittsburgh. Steve Caritis, M.D, is Professor, Department of Obstetrics and Gynecology, Magee-Womens Hospital, Pittsburgh. Raman Venkataramanan, Ph.D, is Professor, Department of Pharmaceutical Sciences, School of Pharmacy, and Professor, Department of Pathology, School of Medicine, University of Pittsburgh.

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http://dx.doi.org/10.2146/ajhp130466DOI Listing
July 2014

Pharmacokinetics of indomethacin in pregnancy.

Clin Pharmacokinet 2014 Jun;53(6):545-51

Department of Obstetrics and Gynecology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555-0587, USA,

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http://dx.doi.org/10.1007/s40262-014-0133-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164383PMC
June 2014

Nanoanesthesia: a novel, intravenous approach to ankle block in the rat by magnet-directed concentration of ropivacaine-associated nanoparticles.

Anesth Analg 2014 Jun;118(6):1355-62

From the *Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; †Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania; ‡Center for Macromolecular Engineering, Department of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania; §Data Center, Center for Research on Health Care, and ‖Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1213/ANE.0000000000000175DOI Listing
June 2014

Quality assessment of compounded 17-hydroxyprogesterone caproate.

Am J Obstet Gynecol 2014 Jan 4;210(1):47.e1-7. Epub 2013 Nov 4.

Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1016/j.ajog.2013.09.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939712PMC
January 2014

Design and evaluation of a PEGylated lipopeptide equipped with drug-interactive motifs as an improved drug carrier.

AAPS J 2014 Jan 27;16(1):114-24. Epub 2013 Nov 27.

Center for Pharmacogenetics, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, USA.

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http://dx.doi.org/10.1208/s12248-013-9536-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889538PMC
January 2014

Population pharmacokinetics of cyclosporine in transplant recipients.

AAPS J 2013 Oct 18;15(4):901-12. Epub 2013 Jun 18.

Department of Clinical Pharmacology, Genentech Inc, South San Francisco, California, USA.

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http://dx.doi.org/10.1208/s12248-013-9500-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787227PMC
October 2013

Ritonavir and efavirenz significantly alter the metabolism of erlotinib--an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer.

Drug Metab Dispos 2013 Oct 2;41(10):1843-51. Epub 2013 Aug 2.

Department of Pharmaceutical Sciences and Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (V.C.P., R.V.); Molecular Therapeutics Drug Discovery program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania (R.A.P., S.M.C., J.H.B.); Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet and Hospital, Stockholm, Sweden (R.G., S.C.S.); and The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland (M.A.R.).

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http://dx.doi.org/10.1124/dmd.113.052100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781374PMC
October 2013

PharmGKB summary: cyclosporine and tacrolimus pathways.

Pharmacogenet Genomics 2013 Oct;23(10):563-85

Departments of aGenetics bBioengineering, Stanford University, Stanford, California cDepartment of Pharmaceutical Sciences, School of Pharmacy dDepartment of Pathology, School of Medicine, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA eSchool of Pharmacy, University of Queensland, Brisbane, Australia.

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http://dx.doi.org/10.1097/FPC.0b013e328364db84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119065PMC
October 2013

Reply: To PMID 23453884.

Am J Obstet Gynecol 2013 Sep 30;209(3):285-6. Epub 2013 Apr 30.

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http://dx.doi.org/10.1016/j.ajog.2013.04.038DOI Listing
September 2013

Design and characterization of PEG-derivatized vitamin E as a nanomicellar formulation for delivery of paclitaxel.

Mol Pharm 2013 Aug 11;10(8):2880-90. Epub 2013 Jul 11.

Center for Pharmacogenetics, University of Pittsburgh , Pittsburgh, Pennsylvania 15261, United States.

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http://dx.doi.org/10.1021/mp300729yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778165PMC
August 2013

Site-specific immunosuppression in vascularized composite allotransplantation: prospects and potential.

Clin Dev Immunol 2013 13;2013:495212. Epub 2013 Feb 13.

Department of Plastic and Reconstructive Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1155/2013/495212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586464PMC
July 2013

Qualitative and quantitative measures of various compounded formulations of 17-alpha hydroxyprogesterone caproate.

Am J Obstet Gynecol 2013 Jun 20;208(6):470.e1-5. Epub 2013 Feb 20.

Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.ajog.2013.02.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672260PMC
June 2013

Sirolimus pharmacokinetics in early postmyeloablative pediatric blood and marrow transplantation.

Biol Blood Marrow Transplant 2013 Apr 21;19(4):569-75. Epub 2012 Dec 21.

Division of Blood and Marrow Transplantation and Cellular Therapies, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.bbmt.2012.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231793PMC
April 2013

PEG-farnesylthiosalicylate conjugate as a nanomicellar carrier for delivery of paclitaxel.

Bioconjug Chem 2013 Mar 1;24(3):464-72. Epub 2013 Mar 1.

Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1021/bc300608hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623935PMC
March 2013

PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers.

Biomaterials 2013 Feb 23;34(5):1591-600. Epub 2012 Nov 23.

Center for Pharmacogenetics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2012.10.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529003PMC
February 2013

Effect of endogenous steroid hormones on 17-alpha-hydroxyprogesterone caproate metabolism.

Am J Obstet Gynecol 2013 Jan 28;208(1):86.e1-6. Epub 2012 Sep 28.

Magee-Womens Hospital, Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Maternal-Fetal Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.ajog.2012.09.021DOI Listing
January 2013

Treprostinil Improves Hepatic Cytochrome P450 Activity during Rat Liver Transplantation.

J Clin Exp Hepatol 2012 Dec 12;2(4):323-32. Epub 2012 Oct 12.

University of Pittsburgh School of Pharmacy, Department of Pharmaceutical Sciences, Pittsburgh, PA, USA ; School of Medicine, Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.jceh.2012.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940493PMC
December 2012