Publications by authors named "Rama S Singh"

41Publications

Genes and genomes and unnecessary complexity in precision medicine.

NPJ Genom Med 2020 4;5:21. Epub 2020 May 4.

Department of Biology, Origins Institute, McMaster University, 1280 Main Street West, Hamilton, ON Canada.

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May 2020

Mate Choice and the Persistence of Maternal Mortality.

Reprod Sci 2019 04 13;26(4):450-458. Epub 2018 Dec 13.

1 Department of Biology, McMaster University, Hamilton, Canada.

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April 2019

A Theory for the Origin of Human Menopause.

Front Genet 2016 6;7:222. Epub 2017 Jan 6.

Department of Biology, Origins Institute, McMaster University, Hamilton ON, Canada.

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January 2017

Science beyond boundary: are premature discoveries things of the past?

Authors:
Rama S Singh

Genome 2016 Jun 3;59(6):433-7. Epub 2016 May 3.

Department of Biology, McMaster University, 1280 Main St. West, Hamilton, ON L8S 4K1, Canada.

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June 2016

Female Choice or Male Sex Drive? The Advantages of Male Body Size during Mating in Drosophila Melanogaster.

PLoS One 2015 11;10(12):e0144672. Epub 2015 Dec 11.

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada.

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June 2016

Maternal effect and speciation: maternal effect contributes to the evolution of hybrid inviability between Drosophila simulans and Drosophila mauritiana.

Genome 2015 Sep 19;58(9):405-13. Epub 2015 Aug 19.

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.

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September 2015

Limits of imagination: the 150th Anniversary of Mendel's Laws, and why Mendel failed to see the importance of his discovery for Darwin's theory of evolution.

Authors:
Rama S Singh

Genome 2015 Sep 15;58(9):415-21. Epub 2015 Aug 15.

Department of Biology, McMaster University, 1280 Main St. West, Hamilton, ON L8S 4K1, Canada.

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September 2015

Darwin's legacy II: why biology is not physics, or why it has taken a century to see the dependence of genes on the environment.

Authors:
Rama S Singh

Genome 2015 Jan 15;58(1):55-62. Epub 2015 Apr 15.

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.

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January 2015

Evolution of Drosophila sex comb length illustrates the inextricable interplay between selection and variation.

Proc Natl Acad Sci U S A 2014 Sep 2;111(39):E4103-9. Epub 2014 Sep 2.

Department of Cell and System Biology, University of Toronto, Toronto, ON, Canada M5S 3G5;

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September 2014

Mate choice and the origin of menopause.

PLoS Comput Biol 2013 13;9(6):e1003092. Epub 2013 Jun 13.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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January 2014

Darwin's legacy: why biology is not physics, or why evolution has not become a common sense.

Authors:
Rama S Singh

Genome 2011 Oct 23;54(10):868-73. Epub 2011 Sep 23.

Department of Biology, McMaster University, Hamilton, ON, Canada.

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October 2011

Is speciation accompanied by rapid evolution? Insights from comparing reproductive and nonreproductive transcriptomes in Drosophila.

Int J Evol Biol 2011 22;2011:595121. Epub 2011 Aug 22.

Department of Biology, McMaster University, Hamilton, ON, Canada L8S 4KI.

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November 2011

Condition dependence and the nature of genetic variation for male sex comb bristle number in Drosophila melanogaster.

Genetica 2011 Apr 5;139(4):505-10. Epub 2011 Apr 5.

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada.

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April 2011

Molecular evidence for increased regulatory conservation during metamorphosis, and against deleterious cascading effects of hybrid breakdown in Drosophila.

BMC Biol 2010 Mar 31;8:26. Epub 2010 Mar 31.

Department of Biology, McMaster University, Hamilton, Ontario, L8S4K1, Canada.

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March 2010

Male sex drive and the maintenance of sex: evidence from Drosophila.

J Hered 2010 Mar-Apr;101 Suppl 1:S100-6. Epub 2010 Mar 8.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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September 2010

Demystifying phenotypes: The comparative genomics of evo-devo.

Fly (Austin) 2010 Jan-Mar;4(1):18-20. Epub 2010 Jan 2.

Department of Biology, McMaster University, Hamilton, ON, Canada.

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August 2010

Ontogeny and phylogeny: molecular signatures of selection, constraint, and temporal pleiotropy in the development of Drosophila.

BMC Biol 2009 Jul 21;7:42. Epub 2009 Jul 21.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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July 2009

The molecular basis of speciation: from patterns to processes, rules to mechanisms.

J Genet 2008 Dec;87(4):327-38

Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

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December 2008

Variation and evolution of male sex combs in Drosophila: nature of selection response and theories of genetic variation for sexual traits.

Genetics 2008 May;179(1):503-9

Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada.

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May 2008

Association between levels of coding sequence divergence and gene misregulation in Drosophila male hybrids.

J Mol Evol 2007 Dec 20;65(6):697-704. Epub 2007 Nov 20.

Department of Biology, McMaster University, Life Science Building 540, 1280 Main Street West, L8S 4K1 Hamilton, Ontario, Canada.

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December 2007

Evolution of genes and genomes on the Drosophila phylogeny.

Authors:
Andrew G Clark Michael B Eisen Douglas R Smith Casey M Bergman Brian Oliver Therese A Markow Thomas C Kaufman Manolis Kellis William Gelbart Venky N Iyer Daniel A Pollard Timothy B Sackton Amanda M Larracuente Nadia D Singh Jose P Abad Dawn N Abt Boris Adryan Montserrat Aguade Hiroshi Akashi Wyatt W Anderson Charles F Aquadro David H Ardell Roman Arguello Carlo G Artieri Daniel A Barbash Daniel Barker Paolo Barsanti Phil Batterham Serafim Batzoglou Dave Begun Arjun Bhutkar Enrico Blanco Stephanie A Bosak Robert K Bradley Adrianne D Brand Michael R Brent Angela N Brooks Randall H Brown Roger K Butlin Corrado Caggese Brian R Calvi A Bernardo de Carvalho Anat Caspi Sergio Castrezana Susan E Celniker Jean L Chang Charles Chapple Sourav Chatterji Asif Chinwalla Alberto Civetta Sandra W Clifton Josep M Comeron James C Costello Jerry A Coyne Jennifer Daub Robert G David Arthur L Delcher Kim Delehaunty Chuong B Do Heather Ebling Kevin Edwards Thomas Eickbush Jay D Evans Alan Filipski Sven Findeiss Eva Freyhult Lucinda Fulton Robert Fulton Ana C L Garcia Anastasia Gardiner David A Garfield Barry E Garvin Greg Gibson Don Gilbert Sante Gnerre Jennifer Godfrey Robert Good Valer Gotea Brenton Gravely Anthony J Greenberg Sam Griffiths-Jones Samuel Gross Roderic Guigo Erik A Gustafson Wilfried Haerty Matthew W Hahn Daniel L Halligan Aaron L Halpern Gillian M Halter Mira V Han Andreas Heger LaDeana Hillier Angie S Hinrichs Ian Holmes Roger A Hoskins Melissa J Hubisz Dan Hultmark Melanie A Huntley David B Jaffe Santosh Jagadeeshan William R Jeck Justin Johnson Corbin D Jones William C Jordan Gary H Karpen Eiko Kataoka Peter D Keightley Pouya Kheradpour Ewen F Kirkness Leonardo B Koerich Karsten Kristiansen Dave Kudrna Rob J Kulathinal Sudhir Kumar Roberta Kwok Eric Lander Charles H Langley Richard Lapoint Brian P Lazzaro So-Jeong Lee Lisa Levesque Ruiqiang Li Chiao-Feng Lin Michael F Lin Kerstin Lindblad-Toh Ana Llopart Manyuan Long Lloyd Low Elena Lozovsky Jian Lu Meizhong Luo Carlos A Machado Wojciech Makalowski Mar Marzo Muneo Matsuda Luciano Matzkin Bryant McAllister Carolyn S McBride Brendan McKernan Kevin McKernan Maria Mendez-Lago Patrick Minx Michael U Mollenhauer Kristi Montooth Stephen M Mount Xu Mu Eugene Myers Barbara Negre Stuart Newfeld Rasmus Nielsen Mohamed A F Noor Patrick O'Grady Lior Pachter Montserrat Papaceit Matthew J Parisi Michael Parisi Leopold Parts Jakob S Pedersen Graziano Pesole Adam M Phillippy Chris P Ponting Mihai Pop Damiano Porcelli Jeffrey R Powell Sonja Prohaska Kim Pruitt Marta Puig Hadi Quesneville Kristipati Ravi Ram David Rand Matthew D Rasmussen Laura K Reed Robert Reenan Amy Reily Karin A Remington Tania T Rieger Michael G Ritchie Charles Robin Yu-Hui Rogers Claudia Rohde Julio Rozas Marc J Rubenfield Alfredo Ruiz Susan Russo Steven L Salzberg Alejandro Sanchez-Gracia David J Saranga Hajime Sato Stephen W Schaeffer Michael C Schatz Todd Schlenke Russell Schwartz Carmen Segarra Rama S Singh Laura Sirot Marina Sirota Nicholas B Sisneros Chris D Smith Temple F Smith John Spieth Deborah E Stage Alexander Stark Wolfgang Stephan Robert L Strausberg Sebastian Strempel David Sturgill Granger Sutton Granger G Sutton Wei Tao Sarah Teichmann Yoshiko N Tobari Yoshihiko Tomimura Jason M Tsolas Vera L S Valente Eli Venter J Craig Venter Saverio Vicario Filipe G Vieira Albert J Vilella Alfredo Villasante Brian Walenz Jun Wang Marvin Wasserman Thomas Watts Derek Wilson Richard K Wilson Rod A Wing Mariana F Wolfner Alex Wong Gane Ka-Shu Wong Chung-I Wu Gabriel Wu Daisuke Yamamoto Hsiao-Pei Yang Shiaw-Pyng Yang James A Yorke Kiyohito Yoshida Evgeny Zdobnov Peili Zhang Yu Zhang Aleksey V Zimin Jennifer Baldwin Amr Abdouelleil Jamal Abdulkadir Adal Abebe Brikti Abera Justin Abreu St Christophe Acer Lynne Aftuck Allen Alexander Peter An Erica Anderson Scott Anderson Harindra Arachi Marc Azer Pasang Bachantsang Andrew Barry Tashi Bayul Aaron Berlin Daniel Bessette Toby Bloom Jason Blye Leonid Boguslavskiy Claude Bonnet Boris Boukhgalter Imane Bourzgui Adam Brown Patrick Cahill Sheridon Channer Yama Cheshatsang Lisa Chuda Mieke Citroen Alville Collymore Patrick Cooke Maura Costello Katie D'Aco Riza Daza Georgius De Haan Stuart DeGray Christina DeMaso Norbu Dhargay Kimberly Dooley Erin Dooley Missole Doricent Passang Dorje Kunsang Dorjee Alan Dupes Richard Elong Jill Falk Abderrahim Farina Susan Faro Diallo Ferguson Sheila Fisher Chelsea D Foley Alicia Franke Dennis Friedrich Loryn Gadbois Gary Gearin Christina R Gearin Georgia Giannoukos Tina Goode Joseph Graham Edward Grandbois Sharleen Grewal Kunsang Gyaltsen Nabil Hafez Birhane Hagos Jennifer Hall Charlotte Henson Andrew Hollinger Tracey Honan Monika D Huard Leanne Hughes Brian Hurhula M Erii Husby Asha Kamat Ben Kanga Seva Kashin Dmitry Khazanovich Peter Kisner Krista Lance Marcia Lara William Lee Niall Lennon Frances Letendre Rosie LeVine Alex Lipovsky Xiaohong Liu Jinlei Liu Shangtao Liu Tashi Lokyitsang Yeshi Lokyitsang Rakela Lubonja Annie Lui Pen MacDonald Vasilia Magnisalis Kebede Maru Charles Matthews William McCusker Susan McDonough Teena Mehta James Meldrim Louis Meneus Oana Mihai Atanas Mihalev Tanya Mihova Rachel Mittelman Valentine Mlenga Anna Montmayeur Leonidas Mulrain Adam Navidi Jerome Naylor Tamrat Negash Thu Nguyen Nga Nguyen Robert Nicol Choe Norbu Nyima Norbu Nathaniel Novod Barry O'Neill Sahal Osman Eva Markiewicz Otero L Oyono Christopher Patti Pema Phunkhang Fritz Pierre Margaret Priest Sujaa Raghuraman Filip Rege Rebecca Reyes Cecil Rise Peter Rogov Keenan Ross Elizabeth Ryan Sampath Settipalli Terry Shea Ngawang Sherpa Lu Shi Diana Shih Todd Sparrow Jessica Spaulding John Stalker Nicole Stange-Thomann Sharon Stavropoulos Catherine Stone Christopher Strader Senait Tesfaye Talene Thomson Yama Thoulutsang Dawa Thoulutsang Kerri Topham Ira Topping Tsamla Tsamla Helen Vassiliev Andy Vo Tsering Wangchuk Tsering Wangdi Michael Weiand Jane Wilkinson Adam Wilson Shailendra Yadav Geneva Young Qing Yu Lisa Zembek Danni Zhong Andrew Zimmer Zac Zwirko David B Jaffe Pablo Alvarez Will Brockman Jonathan Butler CheeWhye Chin Sante Gnerre Manfred Grabherr Michael Kleber Evan Mauceli Iain MacCallum

Nature 2007 Nov;450(7167):203-18

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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November 2007

Rapid evolution of outer egg membrane proteins in the Drosophila melanogaster subgroup: a case of ecologically driven evolution of female reproductive traits.

Mol Biol Evol 2007 Apr 22;24(4):929-38. Epub 2007 Jan 22.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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April 2007

Gene regulation divergence is a major contributor to the evolution of Dobzhansky-Muller incompatibilities between species of Drosophila.

Mol Biol Evol 2006 Sep 6;23(9):1707-14. Epub 2006 Jun 6.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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September 2006

A genomic comparison of faster-sex, faster-X, and faster-male evolution between Drosophila melanogaster and Drosophila pseudoobscura.

J Mol Evol 2006 Jun 11;62(6):693-700. Epub 2006 Apr 11.

Department of Biology, McMaster University, 1280 Main Street W, Hamilton, Ontario, L8S 4K1, Canada.

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June 2006

Sex-specific functional specialization and the evolutionary rates of essential fertility genes.

J Mol Evol 2005 Nov 20;61(5):650-8. Epub 2005 Oct 20.

Department of Biology, McMaster University, Hamilton, Ontario L8S 1J4, Canada.

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November 2005

Rapidly evolving genes of Drosophila: differing levels of selective pressure in testis, ovary, and head tissues between sibling species.

Mol Biol Evol 2005 Sep 25;22(9):1793-801. Epub 2005 May 25.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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September 2005

Male sex drive and the masculinization of the genome.

Bioessays 2005 May;27(5):518-25

Department of Biology, McMaster University, Hamilton, ON, Canada.

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May 2005

Rapid evolution through gene duplication and subfunctionalization of the testes-specific alpha4 proteasome subunits in Drosophila.

Genetics 2004 Nov;168(3):1421-32

Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada.

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November 2004

The nature of genetic variation in sex and reproduction-related genes among sibling species of the Drosophila melanogaster complex.

Genetica 2004 Mar;120(1-3):245-52

Department of Biology, McMaster University, Hamilton, Ont., Canada L8S 4K1.

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March 2004

Darwin to DNA, molecules to morphology: the end of classical population genetics and the road ahead.

Authors:
Rama S Singh

Genome 2003 Dec;46(6):938-42

Department of Biology, McMaster University, Hamilton, ON, Canada.

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December 2003

Sex-linked mammalian sperm proteins evolve faster than autosomal ones.

Mol Biol Evol 2003 Oct 27;20(10):1705-9. Epub 2003 Jun 27.

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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October 2003

Mammalian sperm proteins are rapidly evolving: evidence of positive selection in functionally diverse genes.

Mol Biol Evol 2002 Nov;19(11):1973-80

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

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November 2002

SEX AND SPECIATION: GENETIC ARCHITECTURE AND EVOLUTIONARY POTENTIAL OF SEXUAL VERSUS NONSEXUAL TRAITS IN THE SIBLING SPECIES OF THE DROSOPHILA MELANOGASTER COMPLEX.

Evolution 1998 Aug;52(4):1080-1092

Department of Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada.

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August 1998

THE NATURE OF GENETIC VARIATION FOR SPECIES FORMATION.

Evolution 1984 May;38(3):689-692

Department of Biology, McMaster University, Hamilton, Ontario, Canada, L8S 4K1.

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May 1984