Ralph R Weichselbaum

Ralph R Weichselbaum

UNVERIFIED PROFILE

Are you Ralph R Weichselbaum?   Register this Author

Register author
Ralph R Weichselbaum

Ralph R Weichselbaum

Publications by authors named "Ralph R Weichselbaum"

Are you Ralph R Weichselbaum?   Register this Author

100Publications

2882Reads

23Profile Views

Repurposing Drugs for Cancer Radiotherapy: Early Successes and Emerging Opportunities.

Cancer J 2019 Mar/Apr;25(2):106-115

From the Winship Cancer Institute, Emory University, Atlanta, GA; and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PPO.0000000000000369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518392PMC
March 2020

Integrated molecular and clinical staging defines the spectrum of metastatic cancer.

Nat Rev Clin Oncol 2019 Sep;16(9):581-588

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41571-019-0220-6DOI Listing
September 2019

Beyond Palliation: The Rationale for Metastasis-Directed Therapy for Metastatic Non-Small Cell Lung Cancer.

J Thorac Oncol 2019 Sep 2;14(9):1510-1512. Epub 2019 Jul 2.

Department of Radiation and Cellular Oncology, The University of Chicago Medicine, Chicago, Illinois. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2019.05.025DOI Listing
September 2019

Tumor-reprogrammed resident T cells resist radiation to control tumors.

Nat Commun 2019 Sep 2;10(1):3959. Epub 2019 Sep 2.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-11906-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718618PMC
September 2019

Integration of radiotherapy and immunotherapy for treatment of oligometastases.

Lancet Oncol 2019 Aug 29;20(8):e434-e442. Epub 2019 Jul 29.

Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, USA; Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(19)30157-3DOI Listing
August 2019

STING (or SRC) Like an ICB: Priming the Immune Response in Pancreatic Cancer.

Cancer Res 2019 Aug;79(15):3815-3817

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-19-1700DOI Listing
August 2019

Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer.

Biomaterials 2019 Jul 28;210:94-104. Epub 2019 Apr 28.

Department of Chemistry, The University of Chicago, Chicago, IL, 60637, USA; Department of Radiation and Cellular Oncology and the Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL, 60637, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biomaterials.2019.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579118PMC
July 2019

Staging the Metastatic Spectrum Through Integration of Clinical and Molecular Features.

J Clin Oncol 2019 May 2;37(15):1270-1276. Epub 2019 Apr 2.

1 University of Chicago Medicine, Chicago, IL.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.18.02021
Publisher Site
http://dx.doi.org/10.1200/JCO.18.02021DOI Listing
May 2019

Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors.

Nat Commun 2019 04 23;10(1):1899. Epub 2019 Apr 23.

Department of Chemistry, The University of Chicago, 929 E 57th St, Chicago, IL, 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09221-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478897PMC
April 2019

Oxygen-Guided Radiation Therapy.

Int J Radiat Oncol Biol Phys 2019 03 8;103(4):977-984. Epub 2018 Nov 8.

National Institutes of Health Center for EPR Imaging In Vivo Physiology, University of Chicago, Chicago, Illinois; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03603016183394
Publisher Site
http://dx.doi.org/10.1016/j.ijrobp.2018.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478443PMC
March 2019

Oligometastatic prostate cancer: Reality or figment of imagination?

Cancer 2019 Feb 6;125(3):340-352. Epub 2018 Dec 6.

Department of Radiation and Cellular Oncology, The University of Chicago Medicine, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cncr.31860
Publisher Site
http://dx.doi.org/10.1002/cncr.31860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587458PMC
February 2019

DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.

Cancer Res 2019 02 11;79(3):650-662. Epub 2018 Dec 11.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-18-0692DOI Listing
February 2019

Overall survival according to immunotherapy and radiation treatment for metastatic non-small-cell lung cancer: a National Cancer Database analysis.

Radiat Oncol 2019 Jan 28;14(1):18. Epub 2019 Jan 28.

Department of Radiation and Cellular Oncology, The University of Chicago Medicine, 5758 S. Maryland Avenue, MC 9006, Chicago, IL, 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13014-019-1222-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348608PMC
January 2019

Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.

Immunity 2018 09 28;49(3):490-503.e4. Epub 2018 Aug 28.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75235-9072, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2018.07.008DOI Listing
September 2018

The 46th David A. Karnofsky Memorial Award Lecture: Oligometastasis-From Conception to Treatment.

J Clin Oncol 2018 Sep 27:JCO1800847. Epub 2018 Sep 27.

Ralph R. Weichselbaum, The University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.18.00847DOI Listing
September 2018

ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response.

Free Radic Biol Med 2018 08 13;123:39-52. Epub 2018 Apr 13.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2018.04.547DOI Listing
August 2018

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

J Clin Oncol 2018 06 13;36(16):1611-1618. Epub 2018 Feb 13.

Jason J. Luke, Jeffrey M. Lemons, Theodore G. Karrison, Sean P. Pitroda, James M. Melotek, Yuanyuan Zha, Hania A. Al-Hallaq, Ainhoa Arina, Nikolai N. Khodarev, Linda Janisch, Paul Chang, Jyoti D. Patel, Gini F. Fleming, John Moroney, Manish R. Sharma, Mark J. Ratain, Thomas F. Gajewski, Ralph R. Weichselbaum, and Steven J. Chmura, The University of Chicago, Chicago, IL; Julia R. White, The Ohio State University, Columbus, OH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.76.2229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978468PMC
June 2018

Retuning the Radio in Radiobiology.

J Natl Cancer Inst 2018 04;110(4):325-326

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djx234DOI Listing
April 2018

JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers.

Mol Cancer Ther 2018 04 21;17(4):732-739. Epub 2018 Feb 21.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-17-0667DOI Listing
April 2018

HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.

Mol Cancer Ther 2018 02 13;17(2):407-418. Epub 2017 Oct 13.

Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-17-0288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805623PMC
February 2018

Association between hospital volume and receipt of treatment and survival in patients with glioblastoma.

J Neurooncol 2017 Dec 23;135(3):529-534. Epub 2017 Aug 23.

Department of Radiation Oncology, University of Colorado, Aurora, CO, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-017-2598-2DOI Listing
December 2017

Survival outcomes for postoperative chemoradiation in intermediate-risk oral tongue cancers.

Head Neck 2017 12 27;39(12):2537-2548. Epub 2017 Sep 27.

Department of Radiation and Cellular Oncology, University of Chicago Medical Center, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hed.24932DOI Listing
December 2017

TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response.

Radiat Res 2017 11 16;188(5):579-590. Epub 2017 Aug 16.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, Illinois 60637.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1667/RR14831.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705057PMC
November 2017

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance.

Nat Commun 2017 11 23;8(1):1736. Epub 2017 Nov 23.

Ludwig Center for Metastasis Research, Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-017-01566-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701019PMC
November 2017

Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer.

Clin Cancer Res 2017 Aug 24;23(15):4493-4500. Epub 2017 Mar 24.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-16-2845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540755PMC
August 2017

Rhythmic radiotherapy beats down TGF-β.

Cell Cycle 2017 08 19;16(15):1391. Epub 2017 Jul 19.

a University of Chicago Department of Radiation and Cellular Oncology Ludwig Center for Metastases , Chicago , IL , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384101.2017.1337970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553403PMC
August 2017

Differences in Survival With Surgery and Postoperative Radiotherapy Compared With Definitive Chemoradiotherapy for Oral Cavity Cancer: A National Cancer Database Analysis.

JAMA Otolaryngol Head Neck Surg 2017 07;143(7):691-699

Department of Radiation and Cellular Oncology, University of Chicago Medical Center, Chicago, Illinois2Department of Radiation Oncology, University of Illinois Hospital and Health Sciences System, Chicago.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoto.2017.0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547927PMC
July 2017

In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.

Mol Ther 2017 07 28;25(7):1588-1595. Epub 2017 Apr 28.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA; Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymthe.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498809PMC
July 2017

Radiotherapy and immunotherapy: a beneficial liaison?

Nat Rev Clin Oncol 2017 Jun 17;14(6):365-379. Epub 2017 Jan 17.

Department of Pathology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, Texas 75235-9072, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2016.211DOI Listing
June 2017

CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.

Cell Rep 2017 03;18(10):2373-2386

Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2017.02.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474321PMC
March 2017

Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer.

J Am Chem Soc 2016 12 15;138(51):16686-16695. Epub 2016 Dec 15.

Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.6b09538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667903PMC
December 2016

Image-Guided Radiotherapy Targets Macromolecules through Altering the Tumor Microenvironment.

Mol Pharm 2016 10 1;13(10):3457-3467. Epub 2016 Sep 1.

Ludwig Center for Metastasis Research, The University of Chicago , 5758 South Maryland Avenue, MC 9006, Chicago, Illinois 60637, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.molpharmaceut.6b00465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103304PMC
October 2016

Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity.

Free Radic Biol Med 2016 10 15;99:110-119. Epub 2016 Jul 15.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2016.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764831PMC
October 2016

Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy.

J Am Chem Soc 2016 09 14;138(38):12502-10. Epub 2016 Sep 14.

Department of Chemistry, The University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.6b06663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673483PMC
September 2016

The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications.

Sci Immunol 2016 Sep 30;1(3). Epub 2016 Sep 30.

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL; Ludwig Center for Metastases Research, The University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciimmunol.aag1266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171206PMC
September 2016

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy.

Nat Commun 2016 08 17;7:12499. Epub 2016 Aug 17.

Department of Chemistry, The University of Chicago, 929 E 57th Street, Chicago, Illinois 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms12499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992065PMC
August 2016

Tumor-associated fibroblasts predominantly come from local and not circulating precursors.

Proc Natl Acad Sci U S A 2016 07 17;113(27):7551-6. Epub 2016 Jun 17.

Department of Pathology, The University of Chicago, Chicago, IL 60637; Committee on Immunology, The University of Chicago, Chicago, IL 60637; Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1600363113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941507PMC
July 2016

Stereotactic body radiotherapy for oligometastatic breast cancer: a new standard of care, or a medical reversal in waiting?

Expert Rev Anticancer Ther 2016 Jun 10;16(6):625-32. Epub 2016 May 10.

c Department of Radiation and Cellular Oncology , The University of Chicago , Chicago , IL , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737140.2016.1178577DOI Listing
June 2016

Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers.

Oncotarget 2016 Jun;7(23):33919-33

Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.8984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085128PMC
June 2016

In Reply to Zaghloul.

Int J Radiat Oncol Biol Phys 2016 06;95(2):855

University of Chicago Pritzker School of Medicine, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2016.01.050DOI Listing
June 2016

Patterns of Failure After Radical Cystectomy for pT3-4 Bladder Cancer: Implications for Adjuvant Radiation Therapy.

Int J Radiat Oncol Biol Phys 2016 Apr 5;94(5):1031-9. Epub 2015 Nov 5.

Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, Illinois. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2015.10.051DOI Listing
April 2016

Response.

J Natl Cancer Inst 2016 Mar 7;108(3). Epub 2016 Jan 7.

Department of Radiation Oncology, University of Illinois at Chicago, Chicago, IL (MK, RRW); Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL (MK, RM, RRW); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX (UM); Department of Radiation Oncology, Yale University, New Haven, CT (ZH); Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX (DJS).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv413DOI Listing
March 2016

Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.

Mol Cancer Res 2016 Feb 4;14(2):173-84. Epub 2015 Nov 4.

Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois. Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-15-0263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755886PMC
February 2016

From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy.

Clin Cancer Res 2016 Jan 11;22(1):20-5. Epub 2015 Sep 11.

The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois. Department of Pathology, The University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-3110DOI Listing
January 2016

Prevalence and Predictors of Inappropriate Delivery of Palliative Thoracic Radiotherapy for Metastatic Lung Cancer.

J Natl Cancer Inst 2015 Dec 30;107(12):djv278. Epub 2015 Sep 30.

Department of Radiation Oncology, University of Illinois at Chicago, Chicago, IL (MK, RRW); Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL (MK, RM, RRW); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX (UM); Department of Radiation Oncology, Yale University, New Haven, CT (ZH); Department of Radiation Oncology, Rush University Medical Center, Chicago, IL (DJS).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862415PMC
December 2015

Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury.

Am J Physiol Lung Cell Mol Physiol 2015 Dec 23;309(12):L1420-9. Epub 2015 Oct 23.

Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, Illinois;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00146.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683317PMC
December 2015

DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.

PLoS One 2014 14;9(7):e102112. Epub 2014 Jul 14.

Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, Illinois, United States of America; The University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102112PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096922PMC
November 2015

Radiotherapy and immune checkpoint blockade: potential interactions and future directions.

Trends Mol Med 2015 Aug 16;21(8):463-5. Epub 2015 Jun 16.

The Ludwig Center for Metastasis Research, University of Chicago, Chicago, IL 60637, USA; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://www.cell.com/trends/molecular-medicine/pdf/S1471-4914
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S147149141500116
Publisher Site
http://dx.doi.org/10.1016/j.molmed.2015.05.007DOI Listing
August 2015

Defining the Benefit of Adjuvant Therapy Following Resection for Intrahepatic Cholangiocarcinoma.

Ann Surg Oncol 2015 Jul 5;22(7):2209-17. Epub 2014 Dec 5.

Department of Surgery, The University of Chicago, Chicago, IL, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1245/s10434-014-4275-4DOI Listing
July 2015

Imaging of tumor clones with differential liver colonization.

Sci Rep 2015 Jun 22;5:10946. Epub 2015 Jun 22.

Department of Radiation and Cellular Oncology, Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL 60637.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep10946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476146PMC
June 2015

Nanomedicine for Combination Therapy of Cancer.

EBioMedicine 2015 May 13;2(5):366-7. Epub 2015 May 13.

Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2015.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486458PMC
May 2015

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.

Nucleic Acids Res 2015 Mar 12;43(6):3180-96. Epub 2015 Mar 12.

Department of Radiation and Cellular Oncology, University of Chicago, Cummings Life Science Center, Box 13, 920 East 58th St., Chicago, IL 60637, USA Department of Microbiology and Molecular Genetics, University of California, Davis, Davis CA 95616, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkv175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381078PMC
March 2015

microRNAs and oligometastasis.

Aging (Albany NY) 2015 Mar;7(3):146-7

The University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394724PMC
http://dx.doi.org/10.18632/aging.100731DOI Listing
March 2015

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.

Clin Cancer Res 2015 Feb 9;21(4):870-81. Epub 2014 Dec 9.

Department of Medicine, The University of Chicago, Chicago, Illinois. The University of Chicago Comprehensive Cancer Center, Chicago, Illinois. Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-2481DOI Listing
February 2015

Increasing radiation therapy dose is associated with improved survival in patients undergoing stereotactic body radiation therapy for stage I non-small-cell lung cancer.

Int J Radiat Oncol Biol Phys 2015 Feb;91(2):344-50

Department of Radiation Oncology, Rush University Medical Center, Chicago, Illinois.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2014.10.002DOI Listing
February 2015

The immunology of ablative radiation.

Semin Radiat Oncol 2015 Jan;25(1):40-5

Department of Radiation and Cellular Oncology, The Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semradonc.2014.07.009DOI Listing
January 2015

Comparison of 3D confromal radiotherapy and intensity modulated radiotherapy with or without simultaneous integrated boost during concurrent chemoradiation for locally advanced head and neck cancers.

PLoS One 2014 8;9(4):e94456. Epub 2014 Apr 8.

Department of Radiation and Cellular Oncology, University of Chicago Medical Center, Chicago, Illinois, United States of America; Department of Radiation Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094456PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979891PMC
December 2014

Combination of linear accelerator-based intensity-modulated total marrow irradiation and myeloablative fludarabine/busulfan: a phase I study.

Biol Blood Marrow Transplant 2014 Dec 16;20(12):2034-41. Epub 2014 Sep 16.

Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois; University of Illinois Cancer Center, Chicago, Illinois. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2014.09.005DOI Listing
December 2014

Loss of Nfkb1 leads to early onset aging.

Aging (Albany NY) 2014 Nov;6(11):931-43

Department of Surgery, Section of Neurosurgery, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276787PMC
http://dx.doi.org/10.18632/aging.100702DOI Listing
November 2014

The effect of radiotherapy dose on survival in stage III non-small-cell lung cancer patients undergoing definitive chemoradiotherapy.

Clin Lung Cancer 2014 Sep 2;15(5):365-71. Epub 2014 Jun 2.

Department of Radiation Oncology, University of Illinois at Chicago, Chicago, IL; Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cllc.2014.05.004DOI Listing
September 2014

Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer.

Oral Oncol 2014 Sep 10;50(9):825-31. Epub 2014 Jul 10.

Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA; The University of Chicago Comprehensive Cancer Center, Chicago, IL 60627, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2014.06.004DOI Listing
September 2014

Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs.

Clin Exp Metastasis 2014 Aug 27;31(6):735-48. Epub 2014 Jun 27.

Department of Surgery, The University of Chicago, MC 5029, 5841 S. Maryland Ave, Chicago, IL, 60637, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10585-014-9664-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138440PMC
August 2014

A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses.

Mol Ther 2014 May 27;22(5):1048-55. Epub 2014 Feb 27.

1] Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama, USA [2] Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA [3] Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mt.2014.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015243PMC
May 2014

An analysis of radiation necrosis of the central nervous system treated with bevacizumab.

J Neurooncol 2014 Apr 7;117(2):321-7. Epub 2014 Feb 7.

Department of Radiation Oncology, University of Illinois at Chicago, 1801 West Taylor Street, Chicago, IL, 60612, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-014-1391-8DOI Listing
April 2014

Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model.

Theor Biol Med Model 2014 Apr 12;11:17. Epub 2014 Apr 12.

Department of Surgery, The University of Chicago Medicine, 5841 S, Maryland Avenue, MC 5094 S-032, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1742-4682-11-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022382PMC
April 2014

Feasibility and toxicity of hypofractionated image guided radiation therapy for large volume limited metastatic disease.

Pract Radiat Oncol 2013 Oct-Dec;3(4):316-22. Epub 2012 Oct 3.

Department of Radiation Oncology, Duke University, Durham, North Carolina. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prro.2012.08.006DOI Listing
March 2014

Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses.

Cancer Cell 2014 Jan;25(1):37-48

IBP-UC Group for Immunotherapy, Chinese Academy of Sciences Key Laboratory for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing 100101, China; Department of Pathology and Committee on Immunology, University of Chicago, Chicago, IL 60637, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2013.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927846PMC
January 2014

RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.

Proc Natl Acad Sci U S A 2014 Jan 13;111(4):E484-91. Epub 2014 Jan 13.

Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, Center for Research Informatics, and The Marjorie B. Kovler Viral Oncology Laboratories, University of Chicago, Chicago, IL 60637.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1323253111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910628PMC
January 2014

Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells.

Oncoimmunology 2013 Sep 9;2(9):e25668. Epub 2013 Jul 9.

Department of Radiation and Cellular Oncology; The Ludwig Center for Metastasis Research; University of Chicago; Chicago, IL USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/onci.25668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850275PMC
September 2013