Publications by authors named "Ralph K Lindemann"

21Publications

Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1.

Mol Biol Cell 2017 Dec 26;28(26):3756-3772. Epub 2017 Oct 26.

BioMed X Innovation Center, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1091/mbc.E17-03-0176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739293PMC
December 2017

Secretory stressors induce intracellular death receptor accumulation to control apoptosis.

Cell Death Dis 2017 10 5;8(10):e3069. Epub 2017 Oct 5.

Metabolism and Signaling in Cancer, BioMed X Innovation Center, Im Neuenheimer Feld 583, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/cddis.2017.466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680588PMC
October 2017

TRAPPC13 modulates autophagy and the response to Golgi stress.

J Cell Sci 2017 Jul 23;130(14):2251-2265. Epub 2017 May 23.

Metabolism and Signaling in Cancer, BioMed X Innovation Center, Im Neuenheimer Feld 583, Heidelberg 69120, Germany

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http://dx.doi.org/10.1242/jcs.199521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518214PMC
July 2017

Cell survival and protein secretion associated with Golgi integrity in response to Golgi stress-inducing agents.

Traffic 2017 08 30;18(8):530-544. Epub 2017 Jun 30.

Metabolism and Signaling in Cancer, BioMed X Innovation Center, Heidelberg, Germany.

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http://dx.doi.org/10.1111/tra.12493DOI Listing
August 2017

Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors.

Blood 2009 Feb 5;113(9):1982-91. Epub 2008 Dec 5.

Cancer Immunology Program, The Peter MacCallum Cancer Centre, Trescowthick Research Laboratories, East Melbourne, Australia.

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http://dx.doi.org/10.1182/blood-2008-05-156851DOI Listing
February 2009

Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist.

Proc Natl Acad Sci U S A 2008 Aug 6;105(32):11317-22. Epub 2008 Aug 6.

Cancer Immunology Program, The Peter MacCallum Cancer Centre, Trescowthick Research Laboratories, St. Andrews Place, East Melbourne 3002, Victoria, Australia.

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http://dx.doi.org/10.1073/pnas.0801868105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516269PMC
August 2008

Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin.

Mol Cancer Ther 2008 May;7(5):1066-79

Cancer Immunology Program, Peter MacCallum Cancer Centre, Trescowthick Research Laboratories, St. Andrews Place, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2256DOI Listing
May 2008

Stroma-initiated hedgehog signaling takes center stage in B-cell lymphoma.

Cancer Res 2008 Feb;68(4):961-4

National Center for Tumor Diseases, Department of Translational Oncology G100, Heidelberg, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5500DOI Listing
February 2008

A central role for Bid in granzyme B-induced apoptosis.

J Biol Chem 2005 Feb 1;280(6):4476-82. Epub 2004 Dec 1.

Cancer Cell Death, Gene Regulation, and Immune Signaling Laboratories, Cancer Immunology Program, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne, Victoria 8006.

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http://dx.doi.org/10.1074/jbc.M410985200DOI Listing
February 2005

Ets1 is an effector of protein kinase Calpha in cancer cells.

Oncogene 2005 Jan;24(4):650-61

Universität Halle-Wittenberg, Universitätsklinik und Poliklinik für Gynäkologie, Ernst-Grube-Str. 40, 06097 Halle (Saale), Germany.

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http://dx.doi.org/10.1038/sj.onc.1208234DOI Listing
January 2005

Histone-deacetylase inhibitors for the treatment of cancer.

Cell Cycle 2004 Jun 14;3(6):779-88. Epub 2004 Jun 14.

Gene Regulation Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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June 2004

Interfering with TGFbeta-induced Smad3 nuclear accumulation differentially affects TGFbeta-dependent gene expression.

Mol Cancer 2003 Mar 19;2:20. Epub 2003 Mar 19.

Institut für Zellbiologie, Abteilung Molekularbiologie, Universität Tübingen, Auf der Morgenstelle 15, 72076 Tübingen, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153548PMC
http://dx.doi.org/10.1186/1476-4598-2-20DOI Listing
March 2003

Splicing variant DeltaVII-Ets1 is downregulated in invasive Ets1-expressing breast cancer cells.

Int J Oncol 2003 Apr;22(4):849-53

Friedrich Miescher Institut, 4058 Basel, Switzerland.

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April 2003

Protein kinase Calpha regulates Ets1 transcriptional activity in invasive breast cancer cells.

Int J Oncol 2003 Apr;22(4):799-805

u Institut für Zellbiologie, Abteilung Molekularbiologie, Universität Tübingen, D-72076 Tübingen, Germany.

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April 2003

Ets2 and protein kinase C epsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells.

Biochem J 2003 Jun;372(Pt 3):787-97

Institut für Zellbiologie, Abteilung Molekularbiologie, Universität Tübingen, Auf der Morgenstelle 15, Germany.

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http://dx.doi.org/10.1042/BJ20030046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223436PMC
June 2003