Ralph Burkhardt

Ralph Burkhardt

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Ralph Burkhardt

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Hyperlipidemia and cardiovascular disease: new insights on lipoprotein(a).

Authors:
Ralph Burkhardt

Curr Opin Lipidol 2019 Jun;30(3):260-261

Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1097/MOL.0000000000000594DOI Listing
June 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
June 2019

Atherosclerosis, myocardial infarction and primary hemostasis: Impact of platelets, von Willebrand factor and soluble glycoprotein VI.

Thromb Res 2019 Jun 25;180:98-104. Epub 2019 Jun 25.

Institute for Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital of Leipzig, Leipzig, Germany; LIFE - Leipzig Research Center for Civilization Diseases, University Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.06.014DOI Listing
June 2019

Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma.

J Lipid Res 2019 Apr 5;60(4):900-908. Epub 2019 Feb 5.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany

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http://dx.doi.org/10.1194/jlr.D084301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446716PMC
April 2019

EGF (Epidermal Growth Factor) Receptor Ligands in Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2019 Apr;12(4):e007212

Department of Electrophysiology, Heart Center Leipzig at University of Leipzig, Germany. (P.S., A.B., D.H.-B., G.H., J.K.).

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http://dx.doi.org/10.1161/CIRCEP.119.007212DOI Listing
April 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 Apr 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

Quantification of Fecal Short Chain Fatty Acids by Liquid Chromatography Tandem Mass Spectrometry-Investigation of Pre-Analytic Stability.

Biomolecules 2019 03 28;9(4). Epub 2019 Mar 28.

Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.

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http://dx.doi.org/10.3390/biom9040121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523859PMC
March 2019

Early Lactate Dynamics in Critically Ill Non-Traumatic Patients in a Resuscitation Room of a German Emergency Department (OBSERvE-Lactate-Study).

J Emerg Med 2019 Feb 8;56(2):135-144. Epub 2018 Dec 8.

Emergency Department, University Hospital of Leipzig, Leipzig, Germany; Emergency Department, University Hospital of Düsseldorf, Düsseldorf, Germany; Working Group Trauma and Resuscitation Room Management, Task Force Emergency Medicine, German Society of Anaesthesiology and Intensive Care Medicine, Nümberg, Germany.

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http://dx.doi.org/10.1016/j.jemermed.2018.10.033DOI Listing
February 2019

Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease.

Atherosclerosis 2019 Feb 9;281:17-24. Epub 2018 Nov 9.

LIFE -Leipzig Research Center for Civilization Diseases, Leipzig University, Philipp-Rosenthal-Strasse 27, 04103 Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Paul-List-Strasse 13-15, 04103 Leipzig, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183146
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http://dx.doi.org/10.1016/j.atherosclerosis.2018.11.006DOI Listing
February 2019

Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction.

Int J Cardiol 2019 Jan 10;274:319-325. Epub 2018 Jul 10.

Cardiovascular Research Unit, Luxembourg Institute of Health, Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.07.042DOI Listing
January 2019

Leptin decreases circulating inflammatory IL-6 and MCP-1 in mice.

Biofactors 2019 Jan 29;45(1):43-48. Epub 2018 Nov 29.

Department of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1002/biof.1457DOI Listing
January 2019

Control of hepatic gluconeogenesis by Argonaute2.

Mol Metab 2018 12 9;18:15-24. Epub 2018 Oct 9.

Max Delbrück Center for Molecular Medicine, Robert Rössle Strasse 10, Berlin, Germany; John Hopkins University, All Children's Hospital, St. Petersburg, Florida, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778183079
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http://dx.doi.org/10.1016/j.molmet.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308973PMC
December 2018

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Authors:
Nora Franceschini Claudia Giambartolomei Paul S de Vries Chris Finan Joshua C Bis Rachael P Huntley Ruth C Lovering Salman M Tajuddin Thomas W Winkler Misa Graff Maryam Kavousi Caroline Dale Albert V Smith Edith Hofer Elisabeth M van Leeuwen Ilja M Nolte Lingyi Lu Markus Scholz Muralidharan Sargurupremraj Niina Pitkänen Oscar Franzén Peter K Joshi Raymond Noordam Riccardo E Marioni Shih-Jen Hwang Solomon K Musani Ulf Schminke Walter Palmas Aaron Isaacs Adolfo Correa Alan B Zonderman Albert Hofman Alexander Teumer Amanda J Cox André G Uitterlinden Andrew Wong Andries J Smit Anne B Newman Annie Britton Arno Ruusalepp Bengt Sennblad Bo Hedblad Bogdan Pasaniuc Brenda W Penninx Carl D Langefeld Christina L Wassel Christophe Tzourio Cristiano Fava Damiano Baldassarre Daniel H O'Leary Daniel Teupser Diana Kuh Elena Tremoli Elmo Mannarino Enzo Grossi Eric Boerwinkle Eric E Schadt Erik Ingelsson Fabrizio Veglia Fernando Rivadeneira Frank Beutner Ganesh Chauhan Gerardo Heiss Harold Snieder Harry Campbell Henry Völzke Hugh S Markus Ian J Deary J Wouter Jukema Jacqueline de Graaf Jacqueline Price Janne Pott Jemma C Hopewell Jingjing Liang Joachim Thiery Jorgen Engmann Karl Gertow Kenneth Rice Kent D Taylor Klodian Dhana Lambertus A L M Kiemeney Lars Lind Laura M Raffield Lenore J Launer Lesca M Holdt Marcus Dörr Martin Dichgans Matthew Traylor Matthias Sitzer Meena Kumari Mika Kivimaki Mike A Nalls Olle Melander Olli Raitakari Oscar H Franco Oscar L Rueda-Ochoa Panos Roussos Peter H Whincup Philippe Amouyel Philippe Giral Pramod Anugu Quenna Wong Rainer Malik Rainer Rauramaa Ralph Burkhardt Rebecca Hardy Reinhold Schmidt Renée de Mutsert Richard W Morris Rona J Strawbridge S Goya Wannamethee Sara Hägg Sonia Shah Stela McLachlan Stella Trompet Sudha Seshadri Sudhir Kurl Susan R Heckbert Susan Ring Tamara B Harris Terho Lehtimäki Tessel E Galesloot Tina Shah Ulf de Faire Vincent Plagnol Wayne D Rosamond Wendy Post Xiaofeng Zhu Xiaoling Zhang Xiuqing Guo Yasaman Saba Abbas Dehghan Adrie Seldenrijk Alanna C Morrison Anders Hamsten Bruce M Psaty Cornelia M van Duijn Deborah A Lawlor Dennis O Mook-Kanamori Donald W Bowden Helena Schmidt James F Wilson James G Wilson Jerome I Rotter Joanna M Wardlaw John Deanfield Julian Halcox Leo-Pekka Lyytikäinen Markus Loeffler Michele K Evans Stéphanie Debette Steve E Humphries Uwe Völker Vilmundur Gudnason Aroon D Hingorani Johan L M Björkegren Juan P Casas Christopher J O'Donnell

Nat Commun 2018 12 3;9(1):5141. Epub 2018 Dec 3.

Intramural Administration Management Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-07340-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277418PMC
December 2018

Genome-wide association study identifies inversion in the locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

Gut 2018 10 28;67(10):1855-1863. Epub 2017 Jul 28.

Department of Molecular and Cell Biology, Center for Exocrine Disorders, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, USA.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2017-314454
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http://dx.doi.org/10.1136/gutjnl-2017-314454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145291PMC
October 2018

Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow-derived macrophages.

J Biol Chem 2018 07 13;293(29):11527-11536. Epub 2018 Jun 13.

From the Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany and

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http://dx.doi.org/10.1074/jbc.RA117.000703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065162PMC
July 2018

Lipid metabolism: spotlight on modulators of lipoprotein lipase activity.

Curr Opin Lipidol 2018 04;29(2):164-165

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig.

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http://dx.doi.org/10.1097/MOL.0000000000000501DOI Listing
April 2018

Human brain arousal in the resting state: a genome-wide association study.

Mol Psychiatry 2018 Apr 27. Epub 2018 Apr 27.

LIFE - Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1038/s41380-018-0052-2DOI Listing
April 2018

Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep.

Chronobiol Int 2016 5;33(7):893-905. Epub 2016 May 5.

a LIFE - Leipzig Research Center for Civilization Diseases , University of Leipzig , Leipzig , Germany.

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http://dx.doi.org/10.1080/07420528.2016.1178275DOI Listing
January 2018

Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin.

Acta Diabetol 2017 Nov 2;54(11):1031-1038. Epub 2017 Sep 2.

Lipid Clinic at the Interdisciplinary Metabolism Center, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00592-017-1036-4DOI Listing
November 2017

Depletion of Jmjd1c impairs adipogenesis in murine 3T3-L1 cells.

Biochim Biophys Acta Mol Basis Dis 2017 07 10;1863(7):1709-1717. Epub 2017 May 10.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04103 Leipzig, Germany; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.05.011DOI Listing
July 2017

Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery.

Atherosclerosis 2017 04 24;259:32-40. Epub 2017 Feb 24.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.02.018DOI Listing
April 2017

Lipid metabolism: from genetic loci to functional understanding.

Curr Opin Lipidol 2017 02;28(1):81-82

aInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital bLIFE - Leipzig Research Center for Civilization Diseases, Leipzig University, Leipzig, Germany.

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http://dx.doi.org/10.1097/MOL.0000000000000380DOI Listing
February 2017

MicroRNAs as Salivary Markers for Periodontal Diseases: A New Diagnostic Approach?

Biomed Res Int 2016 27;2016:1027525. Epub 2016 Jun 27.

Department of Cariology, Endodontology and Periodontology, University of Leipzig, 04109 Leipzig, Germany.

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http://dx.doi.org/10.1155/2016/1027525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939343PMC
January 2017

Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.

J Sleep Res 2016 12 29;25(6):690-701. Epub 2016 Apr 29.

LIFE-Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1111/jsr.12421DOI Listing
December 2016

Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles.

Neuropsychobiology 2015 29;72(2):65-73. Epub 2015 Oct 29.

LIFE - Leipzig Research Centre for Civilization Diseases, Leipzig, Germany.

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http://dx.doi.org/10.1159/000437438DOI Listing
September 2016

Pediatric reference data of serum lipids and prevalence of dyslipidemia: Results from a population-based cohort in Germany.

Clin Biochem 2016 Jul 4;49(10-11):740-9. Epub 2016 Mar 4.

Leipzig University, LIFE-Child-Leipzig Research Center for Civilization Diseases, 04103 Leipzig, Germany; Hospital for Children and Adolescents, University of Leipzig, 04103 Leipzig, Germany; Centre of Paediatric Research (CPL), Leipzig University, 04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2016.02.010DOI Listing
July 2016

Cholesterol metabolism and breast cancer.

Curr Opin Lipidol 2016 Apr;27(2):200-1

aInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig bLIFE - Leipzig Research Center for Civilization Diseases, Leipzig University cUniversity Cancer Center Leipzig (UCCL), University Hospital Leipzig, Germany.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOL.0000000000000285DOI Listing
April 2016

Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin.

Biochim Biophys Acta 2016 01 28;1862(1):113-20. Epub 2015 Oct 28.

University of Leipzig, Department of Endocrinology and Nephrology, 04103 Leipzig, Germany; Leipzig University Medical Center, IFB AdiposityDiseases, 04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.10.022DOI Listing
January 2016

Hyperlipidemia and cardiovascular disease: reinforcement for 'lower is better'.

Authors:
Ralph Burkhardt

Curr Opin Lipidol 2015 Oct;26(5):468-9

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig LIFE - Leipzig Research Center for Civilization Diseases, Leipzig University, Leipzig, Germany.

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http://dx.doi.org/10.1097/MOL.0000000000000221DOI Listing
October 2015

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.

PLoS Genet 2015 Sep 24;11(9):e1005510. Epub 2015 Sep 24.

LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig Germany; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pgen.1005510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581711PMC
September 2015

Genetic association of objective sleep phenotypes with a functional polymorphism in the neuropeptide S receptor gene.

PLoS One 2014 4;9(6):e98789. Epub 2014 Jun 4.

LIFE - Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany; Department of Psychiatry and Psychotherapy, Universität Leipzig, Leipzig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098789PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045816PMC
August 2015

Association of the apolipoprotein E genotype with memory performance and executive functioning in cognitively intact elderly.

Neuropsychology 2015 May 3;29(3):382-387. Epub 2014 Nov 3.

Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig.

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http://dx.doi.org/10.1037/neu0000147DOI Listing
May 2015

SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet.

Atherosclerosis 2015 May 16;240(1):212-5. Epub 2015 Mar 16.

Department of Biomedical, Metabolic and Neural Sciences - Endocrinology Section, University of Modena and Reggio Emilia, Italy; Center for Laboratory Medicine, University Hospital Münster, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150150018
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http://dx.doi.org/10.1016/j.atherosclerosis.2015.03.020DOI Listing
May 2015

The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice.

J Biol Chem 2014 Aug 3;289(34):23353-66. Epub 2014 Jul 3.

From the Institute of Biochemistry, Integrated Research and Treatment Center for Adiposity Diseases.

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http://dx.doi.org/10.1074/jbc.M114.580803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156089PMC
August 2014

Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice.

Arterioscler Thromb Vasc Biol 2011 Apr 20;31(4):775-84. Epub 2011 Jan 20.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstrasse 27, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.110.213843DOI Listing
April 2011

Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice.

Arterioscler Thromb Vasc Biol 2008 Nov 11;28(11):2009-15. Epub 2008 Sep 11.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.108.175257DOI Listing
November 2008

Regulation of arginase-1 expression in macrophages by a protein kinase A type I and histone deacetylase dependent pathway.

J Cell Biochem 2008 Feb;103(2):520-7

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Liebigstrasse 27, 04103 Leipzig, Germany.

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http://doi.wiley.com/10.1002/jcb.21422
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http://dx.doi.org/10.1002/jcb.21422DOI Listing
February 2008

Identification of macrophage arginase I as a new candidate gene of atherosclerosis resistance.

Arterioscler Thromb Vasc Biol 2006 Feb 10;26(2):365-71. Epub 2005 Nov 10.

Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1161/01.ATV.0000195791.83380.4cDOI Listing
February 2006