Ralf Reilmann

Ralf Reilmann

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Ralf Reilmann

Publications by authors named "Ralf Reilmann"

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Movement Disorder Society Task Force Viewpoint: Huntington's Disease Diagnostic Categories.

Mov Disord Clin Pract 2019 Sep 23;6(7):541-546. Epub 2019 Aug 23.

Huntington's Disease Centre, University College London Queen Square Institute of Neurology London United Kingdom.

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http://dx.doi.org/10.1002/mdc3.12808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749806PMC
September 2019

Impaired Isometric Force Matching in Upper and Lower Limbs Revealed by Quantitative Motor Assessments in Huntington's Disease.

J Huntingtons Dis 2019 Aug 21. Epub 2019 Aug 21.

George-Huntington-Institute, Deilmann-Building IV, Technology-Park, Muenster, Germany.

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http://dx.doi.org/10.3233/JHD-190354DOI Listing
August 2019

Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy.

BMC Neurol 2019 Jun 8;19(1):118. Epub 2019 Jun 8.

NeuroCure Clinical Research Center, Charité - University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s12883-019-1339-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556046PMC
June 2019

Defining pediatric huntington disease: Time to abandon the term Juvenile Huntington Disease?

Mov Disord 2019 04 20;34(4):584-585. Epub 2019 Feb 20.

Swiss HD Center, Neurozentrum Siloah and Department of Neurology, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/mds.27640DOI Listing
April 2019

Minipigs as a Large-Brained Animal Model for Huntington's Disease: From Behavior and Imaging to Gene Therapy.

Methods Mol Biol 2018 ;1780:241-266

George-Huntington-Institute, Muenster, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7825-0_13DOI Listing
February 2019

Quantitative Measurements of Motor Function in Alzheimer's Disease, Frontotemporal Dementia, and Dementia with Lewy Bodies: A Proof-of-Concept Study.

Dement Geriatr Cogn Disord 2018 26;46(3-4):168-179. Epub 2018 Sep 26.

Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen,

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http://dx.doi.org/10.1159/000492860DOI Listing
January 2019

Activity Behaviour of Minipigs Transgenic for the Huntington Gene.

J Huntingtons Dis 2019 ;8(1):23-31

George-Huntington-Institute, Technology Park Muenster, Muenster, Germany.

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/JHD-180325DOI Listing
January 2019

Biological Motion Perception in Huntington's Disease.

J Huntingtons Dis 2019 ;8(3):311-321

George-Huntington-Institute, Technology-Park, Muenster, Germany.

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http://dx.doi.org/10.3233/JHD-180337DOI Listing
January 2019

A Feasibility Study of Quantitative Motor Assessments in Children Using the Q-Motor Suite.

J Huntingtons Dis 2019 ;8(3):333-338

Department of Psychiatry, University of Iowa Hospital and Clinics, Iowa City, IA, USA.

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http://dx.doi.org/10.3233/JHD-190353DOI Listing
January 2019

On the rise: Quantitative measures in Huntington's disease.

Mov Disord 2018 08;33(8):1370-1371

George-Huntington-Institute, Technology Park, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.27469DOI Listing
August 2018

Huntington's disease: Current and future therapeutic prospects.

Mov Disord 2018 07 8;33(7):1033-1041. Epub 2018 May 8.

Mount Sinai School of Medicine and Clintrex LLC.

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http://dx.doi.org/10.1002/mds.27363DOI Listing
July 2018

Objective assessment of gait and posture in premanifest and manifest Huntington disease - A multi-center study.

Gait Posture 2018 05 7;62:451-457. Epub 2018 Apr 7.

Department of Neurology, University of Münster, Albert-Schweitzer Campus 1, 48149 Münster, Germany; George-Huntington-Institute, Deilmann-Building IV, Technology-Park, Johann-Krane Weg 27, 48149 Münster, Germany; Institute for Clinical Radiology, University of Münster, Albert-Schweitzer Campus 1, 48149 Münster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain, Research, University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.gaitpost.2018.03.039DOI Listing
May 2018

Motor outcome measures in Huntington disease clinical trials.

Handb Clin Neurol 2017 ;144:209-225

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1016/B978-0-12-801893-4.00018-3DOI Listing
March 2018

Stimulating neural plasticity with real-time fMRI neurofeedback in Huntington's disease: A proof of concept study.

Hum Brain Mapp 2018 03 13;39(3):1339-1353. Epub 2017 Dec 13.

UCL Huntington's Disease Centre, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/hbm.23921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838530PMC
March 2018

Survival End Points for Huntington Disease Trials Prior to a Motor Diagnosis.

JAMA Neurol 2017 11;74(11):1352-1360

Huntington's Disease Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, Queen Square, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2017.2107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710578PMC
November 2017

Deutetrabenazine-Not a Revolution but Welcome Evolution for Treating Chorea in Huntington Disease.

Authors:
Ralf Reilmann

JAMA Neurol 2016 12;73(12):1404-1406

George-Huntington-Institute, Muenster, Germany2Department of Radiology, University of Muenster, Muenster, Germany3Department of Neurodegenerative Diseases, University of Tuebingen, Tuebingen, Germany4Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1001/jamaneurol.2016.3916DOI Listing
December 2016

A randomized, controlled trial of a multi-modal exercise intervention in Huntington's disease.

Parkinsonism Relat Disord 2016 10 1;31:46-52. Epub 2016 Jul 1.

School of Healthcare Sciences, Cardiff University, UK; South East Wales Trials Unit, Centre for Trials Research, Cardiff University, UK.

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http://dx.doi.org/10.1016/j.parkreldis.2016.06.023DOI Listing
October 2016

Wearable Sensors in Huntington Disease: A Pilot Study.

J Huntingtons Dis 2016 06;5(2):199-206

Department of Neurology, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.3233/JHD-160197DOI Listing
June 2016

Neuroimaging of a minipig model of Huntington's disease: Feasibility of volumetric, diffusion-weighted and spectroscopic assessments.

J Neurosci Methods 2016 05 1;265:46-55. Epub 2015 Dec 1.

George-Huntington-Institute, Technology Park, Johann-Krane-Weg 27, 48149 Muenster, Germany; Dept of Radiology, University of Muenster, Albert-Schweitzer Campus 1, 48149 Muenster, Germany; Department of Neurology, University of Munster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Hoppe-Seyler Str. 3, 72076 Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2015.11.017DOI Listing
May 2016

Behavioral phenotyping of minipigs transgenic for the Huntington gene.

J Neurosci Methods 2016 05 11;265:34-45. Epub 2015 Dec 11.

George-Huntington-Institute, Technology Park Muenster, Johann-Krane Weg 27 48149, Muenster, Germany; Department of Radiology, Universitaetsklinikum Muenster, Albert-Schweitzer Campus 1 48149, Muenster, Germany; Dept of Neurology Muenster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Hoppe-Seyler Str. 3 72076 Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2015.11.013DOI Listing
May 2016

Digitomotography in Parkinson's disease: a cross-sectional and longitudinal study.

PLoS One 2015 22;10(4):e0123914. Epub 2015 Apr 22.

Hertie Institute for Clinical Brain Research, Department of Neurodegeneration, Center of Neurology, University of Tuebingen, Tuebingen, Germany; George-Huntington-Institute, Technology-Park Muenster, Muenster, Germany; Department of Radiology, University of Muenster, Muenster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123914PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406446PMC
April 2016

Quantitative motor assessment of muscular weakness in myasthenia gravis: a pilot study.

BMC Neurol 2015 Dec 23;15:265. Epub 2015 Dec 23.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s12883-015-0517-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690227PMC
December 2015

Deficits in tongue motor control are linked to microstructural brain damage in multiple sclerosis: a pilot study.

BMC Neurol 2015 Oct 8;15:190. Epub 2015 Oct 8.

George-Huntington-Institute, Technology Park Muenster, Johann-Krane-Weg 27, 48149, Muenster, Germany.

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http://dx.doi.org/10.1186/s12883-015-0451-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599335PMC
October 2015

Quantitative motor assessment of dyskinesias in Parkinson's disease.

J Neural Transm (Vienna) 2015 Sep 25;122(9):1271-8. Epub 2015 Feb 25.

Department of Neurodegeneration, Hertie Institute of Clinical Brain Research, University of Tuebingen, Hoppe Seyler-Strasse 3 , Tuebingen, 72076, Germany,

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http://dx.doi.org/10.1007/s00702-015-1383-7DOI Listing
September 2015

A randomized, placebo-controlled trial of AFQ056 for the treatment of chorea in Huntington's disease.

Mov Disord 2015 Mar 17;30(3):427-31. Epub 2015 Feb 17.

George-Huntington-Institute, Münster, Germany; Institute for Clinical Radiology, University of Münster, Münster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.26174DOI Listing
March 2015

A longitudinal study of magnetic resonance spectroscopy Huntington's disease biomarkers.

Mov Disord 2015 Mar 18;30(3):393-401. Epub 2015 Feb 18.

Centre for Molecular Medicine & Therapeutics, Vancouver, Canada; Centre for Huntington Disease, University of British Columbia (UBC) Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1002/mds.26118DOI Listing
March 2015

Diagnostic criteria for Huntington's disease based on natural history.

Mov Disord 2014 Sep 27;29(11):1335-41. Epub 2014 Aug 27.

George-Huntington-Institute, Technology-Park, Muenster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.26011DOI Listing
September 2014

Huntington's disease: a field on the move. Introduction.

Mov Disord 2014 Sep 27;29(11):1333-4. Epub 2014 Aug 27.

George Huntington Institute, Technology Park, Muenster, Germany; Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.26017DOI Listing
September 2014

Clinical trials in Huntington's disease: Interventions in early clinical development and newer methodological approaches.

Mov Disord 2014 Sep;29(11):1419-28

CHDI Management/CHDI Foundation, Princeton, New Jersey, USA.

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http://dx.doi.org/10.1002/mds.26021DOI Listing
September 2014

The structural correlates of functional deficits in early huntington's disease.

Hum Brain Mapp 2013 Sep 22;34(9):2141-53. Epub 2012 Mar 22.

Center for NeuroImaging Research, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevardde l’Hôpital, Paris Cedex 13, France.

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http://dx.doi.org/10.1002/hbm.22055DOI Listing
September 2013

The pridopidine paradox in Huntington's disease.

Authors:
Ralf Reilmann

Mov Disord 2013 Sep 11;28(10):1321-4. Epub 2013 Jul 11.

Huntington Center, Department of Neurology, University Clinic Muenster (UKM), Westfaelische Wilhelms University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.25559DOI Listing
September 2013

Better global and cognitive functioning in choreatic versus hypokinetic-rigid Huntington's disease.

Mov Disord 2013 Jul 14;28(8):1142-5. Epub 2013 Mar 14.

Leiden University Medical Centre, Department of Neurology, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/mds.25422DOI Listing
July 2013

Pharmacological treatment of chorea in Huntington's disease-good clinical practice versus evidence-based guideline.

Authors:
Ralf Reilmann

Mov Disord 2013 Jul 14;28(8):1030-3. Epub 2013 May 14.

Huntington Group, Department of Neurology, University Clinic Muenster, Westfaelische Wilhelms University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.25500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842832PMC
July 2013

One-year safety and tolerability profile of pridopidine in patients with Huntington disease.

Neurology 2013 Mar 27;80(12):1086-94. Epub 2013 Feb 27.

Centre for Neurogenetics and Rare Diseases, IRCCS Neuromed, Pozzilli, Italy.

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http://dx.doi.org/10.1212/WNL.0b013e3182886965DOI Listing
March 2013

An important step towards translation of stem cell therapies in clinical applications for neurodegenerative diseases and beyond?

Authors:
Ralf Reilmann

Mov Disord 2012 Sep;27(11):1355-6

EHDN Huntington Center Münster & EHDN Neuroprotective Therapy Working Group, Department of Neurology, University Clinic Muenster, Westfaelische-Wilhelms University of Muenster, Muenster, Germany.

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September 2012

Huntington's disease: objective assessment of posture--a link between motor and functional deficits.

Mov Disord 2012 Apr 12;27(4):555-9. Epub 2012 Jan 12.

Department of Neurology, UKM, University of Muenster, Albert-Schweitzer-Campus 1, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.24908DOI Listing
April 2012

Does chromatin modulation provide the first wet biomarker for Huntington's disease?

Authors:
Ralf Reilmann

Mov Disord 2012 Apr;27(4):473

EHDN Huntington Center Münster & EHDN Neuroprotective Therapy Working Group, Department of Neurology, University Clinic Muenster, Westfaelische-Wilhelms University of Muenster, Albert-Schweitzer Campus 1, Muenster, Germany.

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April 2012

Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease.

Neurol Res Int 2011 19;2011:124256. Epub 2011 May 19.

Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria.

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http://dx.doi.org/10.1155/2011/124256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134994PMC
November 2011

Assessment of involuntary choreatic movements in Huntington's disease--toward objective and quantitative measures.

Mov Disord 2011 Oct 9;26(12):2267-73. Epub 2011 Jun 9.

Department of Neurology, University Clinic Muenster, Westfaelische Wilhelms University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.23816DOI Listing
October 2011

Self-awareness of motor dysfunction in patients with Huntington's disease in comparison to Parkinson's disease and cervical dystonia.

J Int Neuropsychol Soc 2011 Sep 8;17(5):788-95. Epub 2011 Jun 8.

Department of Neurological and Psychiatric Nursing, Medical University of Gdansk, Poland.

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http://dx.doi.org/10.1017/S1355617711000725DOI Listing
September 2011

Progression of premanifest and early Huntington's disease detectable after 1 year—does TRACK-HD open the door to disease-modifying trials in HD and beyond?

Authors:
Ralf Reilmann

Mov Disord 2011 Mar;26(4):605

Department of Neurology, University Clinic Muenster, Westfaelische-Wilhelms University of Muenster, Muenster, Germany.

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March 2011

Grasping premanifest Huntington's disease - shaping new endpoints for new trials.

Mov Disord 2010 Dec;25(16):2858-62

Department of Neurology, University Clinic Muenster (UKM), Westfaelische Wilhelms University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.23300DOI Listing
December 2010

Tongue force analysis assesses motor phenotype in premanifest and symptomatic Huntington's disease.

Mov Disord 2010 Oct;25(13):2195-202

Department of Neurology, University Clinic Muenster, Westfaelische Wilhelms University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/mds.23243DOI Listing
October 2010

The role of complex I genes in MELAS: a novel heteroplasmic mutation 3380G>A in ND1 of mtDNA.

Neuromuscul Disord 2008 Jul 30;18(7):553-6. Epub 2008 Jun 30.

Friedrich-Baur-Institute, Department of Neurology, Ludwig-Maximilians-University, Munich, Ziemssenstr. 1, 80336 Munich, Germany.

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http://dx.doi.org/10.1016/j.nmd.2008.05.002DOI Listing
July 2008

FLAIR imaging for multiple sclerosis: a comparative MR study at 1.5 and 3.0 Tesla.

Eur Radiol 2006 Apr 20;16(4):915-21. Epub 2005 Dec 20.

Department of Clinical Radiology, University of Muenster, Germany.

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http://dx.doi.org/10.1007/s00330-005-0070-8DOI Listing
April 2006

Creatine supplementation lowers brain glutamate levels in Huntington's disease.

J Neurol 2005 Jan;252(1):36-41

Department of Neurology, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1007/s00415-005-0595-4DOI Listing
January 2005

Fracture of the odontoid process complicating tardive dystonia.

Mov Disord 2004 Aug;19(8):983-5

Department of Neurology, Department of Psychiatry, University of Muenster, Germany.

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http://dx.doi.org/10.1002/mds.20122DOI Listing
August 2004

Coordination of fingertip forces during precision grasping in multiple system atrophy.

Neuropsychologia 2003 ;41(11):1498-508

Department of Biobehavioral Science, Teachers College, Columbia University, 525 West 120th Street, New York, NY 10027, USA.

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http://dx.doi.org/10.1016/s0028-3932(03)00092-7DOI Listing
September 2003

Selective use of visual information signaling objects' center of mass for anticipatory control of manipulative fingertip forces.

Exp Brain Res 2003 May 21;150(1):9-18. Epub 2003 Mar 21.

Department of Biobehavioral Sciences, Box 199, Teachers College, Columbia University, 525 West 120th Street, NY 10027, New York, USA.

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http://dx.doi.org/10.1007/s00221-003-1394-8DOI Listing
May 2003