Ralf R Schumann

Ralf R Schumann

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Ralf R Schumann

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RNA Sensing of and Its Impact on TB Vaccination Strategies.

Vaccines (Basel) 2020 Feb 4;8(1). Epub 2020 Feb 4.

Department of Microbiology, Infectious Diseases and Immunology, Charité - University Medical Center Berlin, 12203 Berlin, Germany.

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http://dx.doi.org/10.3390/vaccines8010067DOI Listing
February 2020

A SNP upstream of the cyclic GMP-AMP synthase (cGAS) gene protects from relapse and extra-pulmonary TB and relates to BCG vaccination status in an Indian cohort.

Genes Immun 2020 Jan 23;21(1):13-26. Epub 2019 May 23.

Institute for Microbiology and Hygiene, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1038/s41435-019-0080-1DOI Listing
January 2020

STING SNP R293Q Is Associated with a Decreased Risk of Aging-Related Diseases.

Gerontology 2019 26;65(2):145-154. Epub 2018 Oct 26.

Department of Human Epigenetics, Mossakowski Medical Research Center, Polish Academy of Sciences, Warsaw, Poland.

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https://www.karger.com/Article/FullText/492972
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http://dx.doi.org/10.1159/000492972DOI Listing
August 2019

Propionibacterium acnes Abundance Correlates Inversely with Staphylococcus aureus: Data from Atopic Dermatitis Skin Microbiome.

Acta Derm Venereol 2018 Apr;98(5):490-495

Department of Dermatology, Venerology and Allergology, Charité Universitätsmedizin Berlin, DE-10117 Berlin, Germany.

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http://dx.doi.org/10.2340/00015555-2896DOI Listing
April 2018

The cGAS/STING Pathway Detects Streptococcus pneumoniae but Appears Dispensable for Antipneumococcal Defense in Mice and Humans.

Infect Immun 2018 03 20;86(3). Epub 2018 Feb 20.

Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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http://dx.doi.org/10.1128/IAI.00849-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820968PMC
March 2018

The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.

PLoS Pathog 2018 01 3;14(1):e1006829. Epub 2018 Jan 3.

Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1006829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770077PMC
January 2018

Response to Comment on "The Common R71H-G230A-R293Q Human Is a Null Allele".

J Immunol 2017 06;198(11):4185-4188

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610;

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http://dx.doi.org/10.4049/jimmunol.1700322DOI Listing
June 2017

The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele.

J Immunol 2017 01 7;198(2):776-787. Epub 2016 Dec 7.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610;

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http://dx.doi.org/10.4049/jimmunol.1601585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225030PMC
January 2017

Polymorphisms of IFN-γ (+874A/T) and IL-12 (+1188A/C) in tuberculosis patients and their household contacts in Hyderabad, India.

Hum Immunol 2016 Jul 22;77(7):559-65. Epub 2016 Apr 22.

Bhagwan Mahavir Medical Research Centre, Hyderabad, Andhra Pradesh, India; Department of Genetics, Osmania University Hyderabad, Telangana, India. Electronic address:

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http://dx.doi.org/10.1016/j.humimm.2016.04.016DOI Listing
July 2016

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.

Proc Natl Acad Sci U S A 2016 Mar 16;113(9):E1266-75. Epub 2016 Feb 16.

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, United Kingdom; Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom; Novartis Institutes of Biomedical Research, 4058 Basel, Switzerland

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http://www.pnas.org/content/early/2016/02/11/1519246113.full
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http://www.pnas.org/lookup/doi/10.1073/pnas.1519246113
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http://dx.doi.org/10.1073/pnas.1519246113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780616PMC
March 2016

TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study.

Immun Ageing 2016 17;13. Epub 2016 Mar 17.

Department of Human Epigenetics, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland ; Department of Geriatrics and Gerontology, Medical Centre of Postgraduate Education, Warsaw, Poland.

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http://dx.doi.org/10.1186/s12979-016-0062-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797164PMC
March 2016

A Promoter Polymorphism of the Vitamin D Metabolism Gene Cyp24a1 is Associated with Severe Atopic Dermatitis in Adults.

Acta Derm Venereol 2016 Feb;96(2):169-72

Klinik für Dermatologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.2340/00015555-2226DOI Listing
February 2016

Erratum: Less functional variants of TLR-1/-6/-10 genes are associated with age.

Immun Ageing 2015 11;12:10. Epub 2015 Aug 11.

Institute of Microbiology and Hygiene, Charité University Medical Center Berlin, Charitéplatz 1, Berlin, 10117 Germany.

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http://dx.doi.org/10.1186/s12979-015-0037-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531438PMC
August 2015

Less functional variants of TLR-1/-6/-10 genes are associated with age.

Immun Ageing 2015 8;12. Epub 2015 Jul 8.

Institute of Microbiology and Hygiene, Charité University Medical Center Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1186/s12979-015-0034-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495943PMC
July 2015

Toll-like receptor 1 variations influence susceptibility and immune response to Mycobacterium tuberculosis.

Tuberculosis (Edinb) 2015 May 28;95(3):328-35. Epub 2015 Feb 28.

Institute for Microbiology and Hygiene, Charité-Universitätsmedizin, Berlin, Germany; Department of Psychosomatic Medicine, Charité-Universitätsmedizin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2015.02.045DOI Listing
May 2015

The course of gastric cancer following surgery is associated with genetic variations of the interleukin-1 receptor antagonist and interleukin-1β.

Gastric Cancer 2015 Jan 21;18(1):77-83. Epub 2014 Feb 21.

Institute for Microbiology and Hygiene, Charité University Medicine Berlin, Hindenburgdamm 27, 12203, Berlin, Germany.

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http://dx.doi.org/10.1007/s10120-014-0349-zDOI Listing
January 2015

Attenuation of myocardial injury by HMGB1 blockade during ischemia/reperfusion is toll-like receptor 2-dependent.

Mediators Inflamm 2013 24;2013:174168. Epub 2013 Nov 24.

Department of Anaesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1155/2013/174168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859028PMC
October 2014

Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control.

J Virol 2014 Jul 16;88(13):7357-66. Epub 2014 Apr 16.

U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachussetts, USA

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http://dx.doi.org/10.1128/JVI.00728-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054446PMC
July 2014

Association of a common TLR-6 polymorphism with coronary artery disease - implications for healthy ageing?

Immun Ageing 2013 Oct 30;10(1):43. Epub 2013 Oct 30.

Institute for Microbiology and Hygiene, Charité University Medical Center, Hindenburgdamm 27, 12003 Berlin, Germany.

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http://dx.doi.org/10.1186/1742-4933-10-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028875PMC
October 2013

Nocardia farcinica activates human dendritic cells and induces secretion of interleukin-23 (IL-23) rather than IL-12p70.

Infect Immun 2012 Dec 17;80(12):4195-202. Epub 2012 Sep 17.

Institute of Microbiology and Hygiene, Department of Infection Immunology, Charité-University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1128/IAI.00741-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497403PMC
December 2012

Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis.

Hum Immunol 2012 Aug 23;73(8):844-51. Epub 2012 Apr 23.

Institute of Medical Immunology, Charite-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1016/j.humimm.2012.04.008DOI Listing
August 2012

Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile.

Am J Trop Med Hyg 2012 Feb;86(2):229-32

Laboratorio Clinico, Clinica Alemana/Universidad de Desarrollo, Santiago, Chile.

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http://dx.doi.org/10.4269/ajtmh.2012.11-0539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269271PMC
February 2012

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients.

Crit Care 2011 5;15(2):R109. Epub 2011 Apr 5.

Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, JW-Goethe-University Hospital, Theodor-Stern-Kai 7, Frankfurt am Main 60590, Germany.

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http://dx.doi.org/10.1186/cc10130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219387PMC
December 2011

Acylated cholesteryl galactosides are ubiquitous glycolipid antigens among Borrelia burgdorferi sensu lato.

FEMS Immunol Med Microbiol 2011 Oct 27;63(1):140-3. Epub 2011 Jun 27.

Institute of Microbiology and Hygiene, Charité - Universitätsmedizin Berlin, Berlin.

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http://dx.doi.org/10.1111/j.1574-695X.2011.00827.xDOI Listing
October 2011

Old and new findings on lipopolysaccharide-binding protein: a soluble pattern-recognition molecule.

Authors:
Ralf R Schumann

Biochem Soc Trans 2011 Aug;39(4):989-93

Institute for Microbiology, Charité University Medical School, Berlin, Germany.

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http://dx.doi.org/10.1042/BST0390989DOI Listing
August 2011

Genetic variation in innate immunity pathways and their potential contribution to the SIRS/CARS debate: evidence from human studies and animal models.

J Innate Immun 2010 30;2(5):381-94. Epub 2010 Apr 30.

Hanse-Klinikum Stralsund, Department of Anaesthesiology, Intensive Care Medicine and Pain Management, Stralsund, Germany.

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http://dx.doi.org/10.1159/000314269DOI Listing
January 2011

The toll-like receptor 1 variant S248N influences placental malaria.

Infect Genet Evol 2010 Aug 15;10(6):785-9. Epub 2010 May 15.

Institute for Microbiology and Hygiene, Charité - University Medical Center, Dorotheenstrasse 96, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.meegid.2010.05.005DOI Listing
August 2010

Chemoenzymatic synthesis of a glycolipid library and elucidation of the antigenic epitope for construction of a vaccine against Lyme disease.

Chemistry 2010 Mar;16(11):3536-44

Institute of Microbiology and Hygiene, Charité-Universitätsmedizin Berlin, Dorotheenstrasse 96, 10117 Berlin, Germany.

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http://dx.doi.org/10.1002/chem.200902205DOI Listing
March 2010

Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions.

J Infect Dis 2009 Jun;199(12):1816-9

Royal Tropical Institute (KIT) Biomedical Research, Department of Dermatology, Academic Medical Center, Amsterdam, The Netherlands.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5991
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http://dx.doi.org/10.1086/599121DOI Listing
June 2009

Genetic influence on bloodstream infections and sepsis.

Int J Antimicrob Agents 2008 Nov 11;32 Suppl 1:S44-50. Epub 2008 Oct 11.

Department for Surgery and Surgical Oncology, Charité University Medical Center, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijantimicag.2008.08.002DOI Listing
November 2008

Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids.

Immunobiology 2008 2;213(3-4):329-40. Epub 2008 Jan 2.

Department for Dermatology and Allergology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S017129850700140
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http://dx.doi.org/10.1016/j.imbio.2007.11.003DOI Listing
July 2008

Genomic variants of TLR1--it takes (TLR-)two to tango.

Eur J Immunol 2007 Aug;37(8):2059-62

Institute for Microbiology and Hygiene, Charité University Medical Center, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200737604DOI Listing
August 2007

Malarial fever: hemozoin is involved but Toll-free.

Authors:
Ralf R Schumann

Proc Natl Acad Sci U S A 2007 Feb 1;104(6):1743-4. Epub 2007 Feb 1.

Institute of Microbiology and Hygiene, Charité-University Medical Center, 10117 Berlin, Germany.

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http://dx.doi.org/10.1073/pnas.0610874104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794284PMC
February 2007

Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii.

J Immunol 2006 Dec;177(12):8785-95

Institut für Mikrobiologie und Hygiene, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin and Campus Mitte, Hindenburgdamm 27, D-12203 Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.177.12.8785DOI Listing
December 2006

Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy.

J Infect Dis 2006 Jul 13;194(2):184-8. Epub 2006 Jun 13.

Institute of Tropical Medicine and International Health, Berlin, Germany.

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http://dx.doi.org/10.1086/505152DOI Listing
July 2006

Streptococcal M protein: a multipotent and powerful inducer of inflammation.

J Immunol 2006 Jul;177(2):1221-8

Department of Clinical Sciences, Section for Clinical and Experimental Infection Medicine, Biomedicinskt Centrum B14, Lund University, Tornavägen 10, SE-221 84 Lund, Sweden.

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http://dx.doi.org/10.4049/jimmunol.177.2.1221DOI Listing
July 2006

The role of lipopolysaccharide-binding protein in modulating the innate immune response.

Microbes Infect 2006 Mar 13;8(3):946-52. Epub 2006 Jan 13.

Institut für Mikrobiologie und Hygiene, Charité-Universitaetsmedizin Berlin, Schumannstrasse 21/22, D-10117 Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S128645790500374
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http://dx.doi.org/10.1016/j.micinf.2005.10.006DOI Listing
March 2006

Toll-like receptor (TLR)-9 promotor polymorphisms and atherosclerosis.

Clin Chim Acta 2006 Feb 24;364(1-2):303-7. Epub 2005 Aug 24.

Institute for Microbiology and Hygiene, Charité University Medical Center, Medicine, Dorotheenstrasse 96, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.cca.2005.07.017DOI Listing
February 2006

Pre- and postoperative cytokine release after in vitro whole blood lipopolysaccharide stimulation and frequent toll-like receptor 4 polymorphisms.

Shock 2006 Feb;25(2):123-8

Robert-Rössle-Klinik, Klinik für Chirurgie und chirurgische Onkologie, Charité-Universitätsmedizin Berlin, Campus Berlin Buch, Kindenberger Weg 80, 13125 Berlin, Germany.

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http://dx.doi.org/10.1097/01.shk.0000190823.44030.e6DOI Listing
February 2006

Non-LPS targets and actions of LPS binding protein (LBP).

J Endotoxin Res 2005 ;11(4):237-42

Pediatrics Infectious Diseases, Cedars Sinai Medical Center, Davis Research Institute, Los Angeles, California, USA.

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http://dx.doi.org/10.1179/096805105X37420DOI Listing
November 2005

A new Toll-road from environment to genes for rheumatic fever?

J Mol Med (Berl) 2005 Jul 24;83(7):500-3. Epub 2005 Jun 24.

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http://dx.doi.org/10.1007/s00109-005-0687-8DOI Listing
July 2005

A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis.

J Mol Med (Berl) 2005 Jun 4;83(6):478-85. Epub 2005 May 4.

Institute for Microbiology and Hygiene, Charité University Medical Center, Humboldt University, Dorotheenstrasse 96, 10117 Berlin, Germany.

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http://dx.doi.org/10.1007/s00109-005-0643-7DOI Listing
June 2005

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease.

Lancet Infect Dis 2005 Mar;5(3):156-64

Division of Pediatrics Infectious Diseases, Cedars Sinai Medical Center, Davis Research Institute, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/S1473-3099(05)01308-3DOI Listing
March 2005

Acute-phase concentrations of lipopolysaccharide (LPS)-binding protein inhibit innate immune cell activation by different LPS chemotypes via different mechanisms.

Infect Immun 2005 Jan;73(1):193-200

Institute for Microbiology and Hygiene, Charité University Medical Center, Humboldt University Berlin, Dorotheenstrasse 96, 10117 Berlin, Germany.

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http://dx.doi.org/10.1128/IAI.73.1.193-200.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC538978PMC
January 2005

Use of locked nucleic acid oligonucleotides as hybridization/FRET probes for quantification of 16S rDNA by real-time PCR.

Biotechniques 2005 Jan;38(1):29-30, 32

Charité University Medical Center, Berlin, Germany.

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http://dx.doi.org/10.2144/05381BM01DOI Listing
January 2005

Host cell-pathogen interface: molecular mechanisms and genetics.

Authors:
Ralf R Schumann

Vaccine 2004 Dec;22 Suppl 1:S21-4

Institute for Microbiology and Hygiene, Charité University Medical Center, Humboldt-University and Free University Berlin, Dorotheenstr. 96, Berlin, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2004.08.012DOI Listing
December 2004

Impaired adrenal stress response in Toll-like receptor 2-deficient mice.

Proc Natl Acad Sci U S A 2004 Nov 16;101(47):16695-700. Epub 2004 Nov 16.

Department of Medicine, Carl Gustav Carus University Hospital, University of Dresden, 01307 Dresden, Germany.

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http://dx.doi.org/10.1073/pnas.0407550101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534518PMC
November 2004

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae.

J Biol Chem 2004 Aug 23;279(35):36426-32. Epub 2004 Jun 23.

Department of Internal Medicine/Infectious Diseases, Charité University Medicine Berlin, 1 Augustenburger Platz, 13353 Berlin, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M403861200
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http://dx.doi.org/10.1074/jbc.M403861200DOI Listing
August 2004

Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses.

J Immunol 2004 Aug;173(4):2683-91

Institut für Mikrobiologie und Hygiene, Charité University Medical Center, Humboldt University, Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.173.4.2683DOI Listing
August 2004

Inhibition of hepatic transcriptional induction of lipopolysaccharide-binding protein by transforming-growth-factor beta 1.

Eur J Immunol 2004 May;34(5):1441-50

Institut für Mikrobiologie und Hygiene, Charité Medical Center, Humboldt-University, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200324874DOI Listing
May 2004

Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes.

J Immunol Methods 2004 Feb;285(2):281-91

Institute for Microbiology and Hygiene, Charite Medical Center, Humboldt University, Dorotheenstrasse, Berlin 96 10117, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00221759030045
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http://dx.doi.org/10.1016/j.jim.2003.12.005DOI Listing
February 2004

Impaired CD14-dependent and independent response of polymorphonuclear leukocytes in preterm infants.

J Perinat Med 2003 ;31(2):176-83

Department of Pediatrics, Benjamin Franklin Medical Center, FU Medical School, Berlin, Germany.

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http://dx.doi.org/10.1515/JPM.2003.024DOI Listing
September 2003

Acylated cholesteryl galactoside as a novel immunogenic motif in Borrelia burgdorferi sensu stricto.

J Biol Chem 2003 Sep 16;278(36):33645-53. Epub 2003 Jun 16.

Institut für Mikrobiologie und Hygiene, Universitätsklinikum Charité, Medizinische Fakultät der Humboldt-Universität zu Berlin, Dorotheenstrasse 96, D-10117 Berlin, Germany.

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http://dx.doi.org/10.1074/jbc.M305799200DOI Listing
September 2003

Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein.

Immunity 2003 Aug;19(2):269-79

Department of Neurology, Universitaetsklinikum Charité, Humboldt University, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/s1074-7613(03)00205-xDOI Listing
August 2003

High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR.

J Mol Med (Berl) 2003 Jun 13;81(6):368-72. Epub 2003 May 13.

Institut für Mikrobiologie und Hygiene, Universitätsklinikum Charité, Medizinische Fakultät, Humboldt-Universität zu Berlin, Dorotheenstrasse 96, 10098, Berlin, Germany.

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http://dx.doi.org/10.1007/s00109-003-0443-xDOI Listing
June 2003

Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.

J Biol Chem 2003 May 19;278(18):15587-94. Epub 2003 Feb 19.

Institut für Mikrobiologie und Hygiene, Universitätsklinikum Charité, Medizinische Fakultät der Humboldt-Universität zu Berlin, Dorotheenstrasse 96, D-10117 Berlin, Germany.

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http://dx.doi.org/10.1074/jbc.M212829200DOI Listing
May 2003

Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages.

Eur J Neurosci 2002 Dec;16(11):2113-22

Max Delbrück Center for Molecular Medicine, Cellular Neurosciences, Robert-Rössle-Strasse 10, D-13092 Berlin, Germany.

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http://dx.doi.org/10.1046/j.1460-9568.2002.02287.xDOI Listing
December 2002

Triptans reduce the inflammatory response in bacterial meningitis.

J Cereb Blood Flow Metab 2002 Aug;22(8):988-96

Department of Neurology, University Hospital Charité, Humboldt University, Berlin, Germany.

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http://journals.sagepub.com/doi/10.1097/00004647-200208000-0
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http://dx.doi.org/10.1097/00004647-200208000-00010DOI Listing
August 2002

Inhibition of LPS-induced activation of alveolar macrophages by high concentrations of LPS-binding protein.

Biochem Biophys Res Commun 2002 Jul;295(2):553-60

Department of Immunology and Cell Biology, Center for Medicine and Bioscience, Borstel, Germany.

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http://dx.doi.org/10.1016/s0006-291x(02)00710-6DOI Listing
July 2002