Ralf Paus

Ralf Paus

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Ralf Paus

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PPAR-γ signalling as a key mediator of human hair follicle physiology and pathology.

Exp Dermatol 2020 Mar 17;29(3):312-321. Epub 2019 Dec 17.

Monasterium Laboratory, Skin and Hair Research Solutions GmbH, Muenster, Germany.

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http://dx.doi.org/10.1111/exd.14062DOI Listing
March 2020

Do hair follicles operate as primitive, multifocal kidney-like excretory (mini-) organs?

Exp Dermatol 2020 Mar;29(3):357-365

Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1111/exd.14076DOI Listing
March 2020

The Phytocannabinoid (-)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects.

J Invest Dermatol 2020 Feb 29;140(2):484-488.e5. Epub 2019 Jul 29.

Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Hungarian Center of Excellence for Molecular Medicine, Szeged, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.07.690DOI Listing
February 2020

Toward Predicting the Spatio-Temporal Dynamics of Alopecia Areata Lesions Using Partial Differential Equation Analysis.

Bull Math Biol 2020 Feb 24;82(3):34. Epub 2020 Feb 24.

Department of Mathematics, Florida State University, 208 Love Building, 1017 Academic Way, Tallahassee, FL, 32306, USA.

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http://dx.doi.org/10.1007/s11538-020-00707-0DOI Listing
February 2020

Schwann cells as underestimated, major players in human skin physiology and pathology.

Exp Dermatol 2020 Jan 2;29(1):93-101. Epub 2019 Dec 2.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1111/exd.14060DOI Listing
January 2020

Neuroendocrinology and neurobiology of sebaceous glands.

Biol Rev Camb Philos Soc 2020 Jan 22. Epub 2020 Jan 22.

Centre for Dermatology, School of Biological Sciences, University of Manchester, and NIHR Manchester Biomedical Research Centre, Stopford Building, Oxford Road, Manchester, M13 9PT, U.K.

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http://dx.doi.org/10.1111/brv.12579DOI Listing
January 2020

Itching for an answer: A review of potential mechanisms of scalp itch in psoriasis.

Exp Dermatol 2019 Dec 15;28(12):1397-1404. Epub 2019 May 15.

Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, Miami Itch Center Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1111/exd.13947DOI Listing
December 2019

Human Perifollicular Macrophages Undergo Apoptosis, Express Wnt Ligands, and Switch their Polarization during Catagen.

J Invest Dermatol 2019 Dec 22;139(12):2543-2546.e9. Epub 2019 Jun 22.

Centre for Dermatology Research, School of Biology, University of Manchester, and NIHR Biomedical Research Centre, Manchester, UK; Dr Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, FL. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.04.026DOI Listing
December 2019

Frontiers in alopecia areata pathobiology research.

J Allergy Clin Immunol 2019 Dec 9;144(6):1478-1489. Epub 2019 Oct 9.

Dr Philipp Frost Department of Dermatology & Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, Fla; Dermatology Research Centre, University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2019.08.035DOI Listing
December 2019

Thyroxine (T4) may promote re-epithelialisation and angiogenesis in wounded human skin ex vivo.

PLoS One 2019 29;14(3):e0212659. Epub 2019 Mar 29.

Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212659PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440638PMC
November 2019

Y-27632 preserves epidermal integrity in a human skin organ-culture (hSOC) system by regulating AKT and ERK signaling pathways.

J Dermatol Sci 2019 Nov 3;96(2):99-109. Epub 2019 Nov 3.

Department of Tissue Engineering and Regeneration, School and Hospital of Stomatology, Shandong University & Shandong Provincial Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Jinan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2019.10.006DOI Listing
November 2019

Adenosine Promotes Human Hair Growth and Inhibits Catagen Transition In Vitro: Role of the Outer Root Sheath Keratinocytes.

J Invest Dermatol 2019 Nov 12. Epub 2019 Nov 12.

DE-MTA 'Lendület' Cellular Physiology Research Group, Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Hungarian Center of Excellence for Molecular Medicine, Szeged, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.08.456DOI Listing
November 2019

Getting ready for the next decade of Experimental Dermatology.

Exp Dermatol 2019 Nov;28(11):1199-1200

Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1111/exd.14052DOI Listing
November 2019

CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane-induced alopecia.

EMBO Mol Med 2019 10 12;11(10):e11031. Epub 2019 Sep 12.

Centre for Dermatology Research, School of Biological Sciences, University of Manchester & NIHR Biomedical Research Centre, Manchester, UK.

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https://onlinelibrary.wiley.com/doi/abs/10.15252/emmm.201911
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http://dx.doi.org/10.15252/emmm.201911031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783643PMC
October 2019

Seborrheic dermatitis-Looking beyond Malassezia.

Exp Dermatol 2019 Sep 19;28(9):991-1001. Epub 2019 Aug 19.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1111/exd.14006DOI Listing
September 2019

Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo.

Skin Pharmacol Physiol 2019 13;32(6):344-348. Epub 2019 Sep 13.

Centre for Dermatology Research, University of Manchester, Manchester, United Kingdom, E-Mail

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https://www.karger.com/Article/FullText/501729
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http://dx.doi.org/10.1159/000501729DOI Listing
September 2019

Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo.

J Invest Dermatol 2019 Jul 17;139(7):1593-1596. Epub 2019 Jan 17.

Centre for Dermatology Research, University of Manchester, and National Institute for Health Research Manchester Biomedical Research Centre, Manchester, UK; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.12.022DOI Listing
July 2019

Inhibition of ATP binding cassette transporter B1 sensitizes human hair follicles to chemotherapy-induced damage.

J Dermatol Sci 2019 07 14;95(1):44-47. Epub 2019 Jun 14.

Centre for Dermatology Research, University of Manchester, and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom; Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2019.06.003DOI Listing
July 2019

The renaissance of human skin organ culture: A critical reappraisal.

Differentiation 2018 Nov - Dec;104:22-35. Epub 2018 Oct 16.

Department of Dermatology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03014681183005
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http://dx.doi.org/10.1016/j.diff.2018.10.002DOI Listing
June 2019

TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro.

J Invest Dermatol 2019 Jun 6;139(6):1385-1388. Epub 2018 Dec 6.

Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.11.020DOI Listing
June 2019

Fibrosis and stem cell epithelial-mesenchymal transition in primary cicatricial alopecias.

J Am Acad Dermatol 2019 06 11;80(6):e165-e166. Epub 2019 Jan 11.

Centre for Dermatology Research, University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Center, Manchester, United Kingdom; National Institute for Health Research Centre Manchester Biomedical Research Centre, Manchester, United Kingdom; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

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https://linkinghub.elsevier.com/retrieve/pii/S01909622193006
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http://dx.doi.org/10.1016/j.jaad.2018.12.055DOI Listing
June 2019

Hair disorders in patients with cancer.

J Am Acad Dermatol 2019 May 14;80(5):1179-1196. Epub 2018 Apr 14.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183052
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http://dx.doi.org/10.1016/j.jaad.2018.03.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186204PMC
May 2019

Hair disorders in cancer survivors.

J Am Acad Dermatol 2019 May 14;80(5):1199-1213. Epub 2018 Apr 14.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2018.03.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186205PMC
May 2019

How chemotherapy and radiotherapy damage the tissue: Comparative biology lessons from feather and hair models.

Exp Dermatol 2019 Apr 21;28(4):413-418. Epub 2018 Dec 21.

Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

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http://doi.wiley.com/10.1111/exd.13846
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http://dx.doi.org/10.1111/exd.13846DOI Listing
April 2019

Bridging the "Dead Hair"-"Live Follicle" Divide in Applied Hair Research.

J Cosmet Sci 2018 Sep/Oct;69(5):315-322

Monasterium Laboratory, Skin and Hair Research Solutions GmbH, Muenster, 48149, Germany (M.B., N.B., C.W.), Centre for Skin Sciences, University of Bradford, Bradford, BD7 1DP England (G.W.), Textile Research Institute, Princeton, New Jersey, 08540, (P.W.), University of Manchester, Manchester, M13 9PT United Kingdom (R.P.), University of Miami, Miami, 33125, Florida (R.P.).

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April 2019

Do human dermal adipocytes switch from lipogenesis in anagen to lipophagy and lipolysis during catagen in the human hair cycle?

Exp Dermatol 2019 Apr 19;28(4):432-435. Epub 2019 Mar 19.

Centre for Dermatology Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13904DOI Listing
April 2019

Hair growth control by innate immunocytes: Perifollicular macrophages revisited.

Exp Dermatol 2019 Apr;28(4):425-431

Centre for Dermatology Research, University of Manchester, and the NIHR Manchester Biomedical Research Centre, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13922DOI Listing
April 2019

Fluorescent cell tracer dye permits real-time assessment of re-epithelialization in a serum-free ex vivo human skin wound assay.

Wound Repair Regen 2019 01 21;27(1):126-133. Epub 2018 Dec 21.

Centre for Dermatology Research, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1111/wrr.12688DOI Listing
January 2019

JAK inhibitors and alopecia areata.

Lancet 2019 01;393(10169):318-319

Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA; Centre for Dermatology Research, University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183298
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http://dx.doi.org/10.1016/S0140-6736(18)32987-8DOI Listing
January 2019

Re-investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

J Histochem Cytochem 2018 12 15;66(12):847-862. Epub 2018 Jun 15.

Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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http://dx.doi.org/10.1369/0022155418782693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262504PMC
December 2018

Retinoic acid co-treatment aggravates severity of dioxin-induced skin lesions in hairless mice via induction of inflammatory response.

Biochem Biophys Res Commun 2018 12 31;506(4):854-861. Epub 2018 Oct 31.

NRC Kurchatov Institute, Moscow, Russian Federation. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.10.126DOI Listing
December 2018

Mechanisms of epithelial thickening due to IL-1 signalling blockade and TNF-α administration differ during wound repair and regeneration.

Differentiation 2018 Jan - Feb;99:10-20. Epub 2017 Dec 12.

Laboratory of Connective Tissue, Centro Nacional de Investigación y Atención de Quemados, Instituto Nacional de Rehabilitación Luís Guillermo Ibarra Ibarra, México-Xochimilco No. 289, Col. Arenal de Guadalupe, Del. Tlalpan, C.P. 14389 Mexico City, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.diff.2017.12.001DOI Listing
November 2018

Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P-induced human mast cell activation and degranulation in the hair follicle.

J Allergy Clin Immunol 2018 10 31;142(4):1331-1333.e8. Epub 2018 May 31.

Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom; Department of Dermatology, University of Miami, Miller School of Medicine, Miami, Fla. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.04.039DOI Listing
October 2018

Analysing the dynamics of a model for alopecia areata as an autoimmune disorder of hair follicle cycling.

Math Med Biol 2018 09;35(3):387-407

Department of Mathematics, Florida State University, Tallahassee, FL, USA.

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http://dx.doi.org/10.1093/imammb/dqx009DOI Listing
September 2018

A technique for more precise distinction between catagen and telogen human hair follicles ex vivo.

J Am Acad Dermatol 2018 Sep 10;79(3):558-559. Epub 2018 Feb 10.

Mediteknia Clinic and Hair Laboratory, Las Palmas, Spain; Universidad Fernando Pessoa Canarias, Las Palmas, Spain; Medical Pathology Group, IUIBS, Universidad de Las Palmas Gran Canaria, Las Palmas, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2018.02.009DOI Listing
September 2018

Olfactory receptor OR2AT4 regulates human hair growth.

Nat Commun 2018 09 18;9(1):3624. Epub 2018 Sep 18.

Centre for Dermatology Research, MAHSC and NIHR Biomedical Research Centre, University of Manchester, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1038/s41467-018-05973-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143528PMC
September 2018

Visualization of global RNA synthesis in a human (mini-) organ in situ by click chemistry.

Biotechniques 2018 08;65(2):97-100

Centre for Dermatology Research, School of Biological Sciences, Stopford Building, Oxford Road, University of Manchester, MAHSC & NIHR Biomedical Research Centre, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.2144/btn-2018-0025DOI Listing
August 2018

Peroxisome Proliferator-Activated Receptor-γ-Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium.

J Invest Dermatol 2018 07 13;138(7):1656-1659. Epub 2018 Feb 13.

Center for Dermatology Research, University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester, UK; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X183011
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http://dx.doi.org/10.1016/j.jid.2018.01.033DOI Listing
July 2018

Innate lymphoid cells 3 induce psoriasis in xenotransplanted healthy human skin.

J Allergy Clin Immunol 2018 07 2;142(1):305-308.e6. Epub 2018 Mar 2.

Skin Research Laboratory, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.02.015DOI Listing
July 2018

Prolactin as a candidate sebotrop(h)ic hormone?

Exp Dermatol 2018 07;27(7):729-736

Dermatology Research Centre, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13545DOI Listing
July 2018

iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata.

J Autoimmun 2018 07 18;91:61-72. Epub 2018 Apr 18.

Skin Research Laboratory, Rappaport Faculty of Medicine, Technion - Institute of Technology, Haifa, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.04.001DOI Listing
July 2018

Dermal white adipose tissue undergoes major morphological changes during the spontaneous and induced murine hair follicle cycling: a reappraisal.

Arch Dermatol Res 2018 Jul 27;310(5):453-462. Epub 2018 Apr 27.

Centre for Dermatology Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s00403-018-1831-yDOI Listing
July 2018

Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo.

J Invest Dermatol 2018 06 26;138(6):1420-1422. Epub 2017 Dec 26.

Centre for Dermatology Research, The University of Manchester, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.12.019DOI Listing
June 2018

An efficient method for eccrine gland isolation from human scalp.

Exp Dermatol 2018 06 3;27(6):678-681. Epub 2018 Apr 3.

The Centre for Dermatology Research, MAHSC, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13505DOI Listing
June 2018

A guide to studying human dermal adipocytes in situ.

Exp Dermatol 2018 06;27(6):589-602

Centre for Dermatology Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13549DOI Listing
June 2018

How UV Light Touches the Brain and Endocrine System Through Skin, and Why.

Endocrinology 2018 05;159(5):1992-2007

Centre for Dermatology Research, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1210/en.2017-03230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905393PMC
May 2018

Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases.

Trends Mol Med 2018 05 13;24(5):435-448. Epub 2018 Apr 13.

Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, UK; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2018.03.007DOI Listing
May 2018

Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles.

PLoS Biol 2018 05 8;16(5):e2003705. Epub 2018 May 8.

Centre for Dermatology Research, University of Manchester, Manchester Academic Health Science Centre and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.2003705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940179PMC
May 2018

Epithelial-to-Mesenchymal Stem Cell Transition in a Human Organ: Lessons from Lichen Planopilaris.

J Invest Dermatol 2018 03 26;138(3):511-519. Epub 2017 Oct 26.

Centre for Dermatology Research, University of Manchester, Manchester Academic Health Science Centre, National Institute for Health Research Biomedical Research Centre, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.09.047DOI Listing
March 2018

Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions.

J Invest Dermatol 2018 03 7;138(3):490-499. Epub 2018 Feb 7.

Centre for Dermatology Research, University of Manchester, and NIHR Manchester Biomedical Research Centre, Manchester, UK.

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http://dx.doi.org/10.1016/j.jid.2017.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828910PMC
March 2018

Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture.

PLoS Biol 2018 03 28;16(3):e2002864. Epub 2018 Mar 28.

Department of Drug Discovery and Development, Laboratory of Molecular Medicine, Fondazione Istituto Italiano di Tecnologia (IIT), Genoa, Italy.

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http://dx.doi.org/10.1371/journal.pbio.2002864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891029PMC
March 2018

NF-κB Participates in Mouse Hair Cycle Control and Plays Distinct Roles in the Various Pelage Hair Follicle Types.

J Invest Dermatol 2018 02 20;138(2):256-264. Epub 2017 Sep 20.

Signal Transduction in Tumor Cells, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.08.042DOI Listing
February 2018

Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management.

J Investig Dermatol Symp Proc 2018 01;19(1):S12-S17

Department of Dermatology, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1016/j.jisp.2017.10.014DOI Listing
January 2018

Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2.

Sci Rep 2017 11 9;7(1):15197. Epub 2017 Nov 9.

Centre for Dermatology Research, School of Biological Sciences, University of Manchester, MAHSC and NIHR Biomedical Research Centre, Manchester, UK.

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http://dx.doi.org/10.1038/s41598-017-15038-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680340PMC
November 2017

Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix.

Eur J Cell Biol 2017 Sep 2;96(6):632-641. Epub 2017 Apr 2.

Centre for Dermatology Research, School of Biological Sciences, University of Manchester, MAHSC and NIHR Biomedical Research Centre, Manchester, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01719335173001
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http://dx.doi.org/10.1016/j.ejcb.2017.03.011DOI Listing
September 2017

E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis.

J Invest Dermatol 2017 08 26;137(8):1731-1739. Epub 2017 Apr 26.

Institute of Life Sciences, Fuzhou University, Fuzhou, Fujian, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X173142
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http://dx.doi.org/10.1016/j.jid.2017.03.036DOI Listing
August 2017

Oxidative stress management in the hair follicle: Could targeting NRF2 counter age-related hair disorders and beyond?

Bioessays 2017 08 7;39(8). Epub 2017 Jul 7.

Centre for Dermatology Research, School of Biological Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/bies.201700029DOI Listing
August 2017

T-cell "induced-self" MHC class I/peptide complexes may enable "de novo" tolerance induction to neo-antigens occurring outside of the thymus: Lessons from the hair follicle.

Exp Dermatol 2017 06 14;26(6):529-531. Epub 2017 Feb 14.

Centre for Dermatology Research, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13238DOI Listing
June 2017

A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling.

Acta Derm Venereol 2017 Jun;97(6):675-684

Plastic and Reconstructive Surgery Research, Stopford Building, Manchester M13 9PT , United Kingdom.

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https://www.medicaljournals.se/acta/content/abstract/10.2340
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http://dx.doi.org/10.2340/00015555-2587DOI Listing
June 2017

Wound healing protects against chemotherapy-induced alopecia in young rats via up-regulating interleukin-1β-mediated signaling.

Heliyon 2017 May 30;3(5):e00309. Epub 2017 May 30.

Wound Healing and Regenerative Medicine Research Program, Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1016/j.heliyon.2017.e00309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454141PMC
May 2017

Enhanced Neurogenic Biomarker Expression and Reinnervation in Human Acute Skin Wounds Treated by Electrical Stimulation.

J Invest Dermatol 2017 03 14;137(3):737-747. Epub 2016 Nov 14.

Plastic Surgery Research Group, Dermatology Research Centre, Institute of Inflammation & Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X163264
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http://dx.doi.org/10.1016/j.jid.2016.09.038DOI Listing
March 2017

Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition.

J Invest Dermatol 2017 02 1;137(2):295-304. Epub 2016 Oct 1.

The Centre for Dermatology Research, School of Biological Sciences, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.08.035DOI Listing
February 2017

Identification of a Potential Molecular Diagnostic Biomarker in Keloid Disease: Syndecan-1 (CD138) Is Overexpressed in Keloid Scar Tissue.

J Invest Dermatol 2016 11 14;136(11):2319-2323. Epub 2016 Jul 14.

Plastic and Reconstructive Surgery Research, University of Manchester, Manchester, UK; The Dermatology Centre, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.06.623DOI Listing
November 2016

The gut-skin axis in health and disease: A paradigm with therapeutic implications.

Bioessays 2016 11 24;38(11):1167-1176. Epub 2016 Aug 24.

Dermatology Research Centre, Institute of Inflammation and Repair, University of Manchester and Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1002/bies.201600008DOI Listing
November 2016

Thyroid Hormones Enhance Mitochondrial Function in Human Epidermis.

J Invest Dermatol 2016 10 25;136(10):2003-2012. Epub 2016 Jun 25.

Department of Dermatology, University of Münster, Münster, Germany; Center for Dermatology Research, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.05.118DOI Listing
October 2016

A primer for studying cell cycle dynamics of the human hair follicle.

Exp Dermatol 2016 09 18;25(9):663-8. Epub 2016 Jul 18.

Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.13046DOI Listing
September 2016

The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo.

J Invest Dermatol 2016 08 8;136(8):1711-1714. Epub 2016 Apr 8.

Department of Dermatology, University of Münster, Münster, Germany; Dermatology Research Center, Institute of Inflammation and Repair, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.03.033DOI Listing
August 2016

Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies.

Autoimmun Rev 2016 Jul 10;15(7):726-35. Epub 2016 Mar 10.

Centre for Dermatology Research, Inst. of Inflammation and Repair, University of Manchester, Manchester, UK; Department of Dermatology, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1016/j.autrev.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365233PMC
July 2016

The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease.

J Invest Dermatol 2016 07 26;136(7):1500-1512. Epub 2016 Mar 26.

Plastic and Reconstructive Surgery Research, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK; Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.03.022DOI Listing
July 2016

Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization.

Stem Cells 2016 05 2;34(5):1377-85. Epub 2016 Feb 2.

The Healing Foundation Centre, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/stem.2289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985639PMC
May 2016

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.

Development 2016 05 7;143(9):1512-22. Epub 2016 Mar 7.

Department of Signal Transduction in Tumor Cells, Max-Delbrück-Center (MDC) for Molecular Medicine, Berlin 13092, Germany

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http://dx.doi.org/10.1242/dev.130898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514410PMC
May 2016

Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice.

Development 2016 05 17;143(10):1823-31. Epub 2016 Mar 17.

Institute of Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Munich 81377, Germany

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http://dx.doi.org/10.1242/dev.132753DOI Listing
May 2016

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle.

PLoS One 2015 30;10(3):e0121878. Epub 2015 Mar 30.

The Dermatology Centre, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom; Department of Dermatology, University of Muenster, Muenster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121878PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379003PMC
April 2016

Hunting the genes in male-pattern alopecia: how important are they, how close are we and what will they tell us?

Exp Dermatol 2016 Apr 26;25(4):251-7. Epub 2016 Feb 26.

Institute of Human Genetics, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1111/exd.12965DOI Listing
April 2016

p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis.

J Invest Dermatol 2016 Mar 30;136(3):680-689. Epub 2015 Dec 30.

Institute of Life Sciences, Fuzhou University, Fuzhou, Fujian, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.12.021DOI Listing
March 2016

Is the eccrine gland an integral, functionally important component of the human scalp pilosebaceous unit?

Exp Dermatol 2016 Feb 12;25(2):149-50. Epub 2016 Jan 12.

Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1111/exd.12889
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http://dx.doi.org/10.1111/exd.12889DOI Listing
February 2016

A Guide to Studying Human Hair Follicle Cycling In Vivo.

J Invest Dermatol 2016 Jan;136(1):34-44

Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California, USA; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA. Electronic address:

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http://dx.doi.org/10.1038/JID.2015.354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785090PMC
January 2016

Human hair follicle organ culture: theory, application and perspectives.

Exp Dermatol 2015 Dec;24(12):903-11

Dermatology Research Centre, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1111/exd.12836
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http://dx.doi.org/10.1111/exd.12836DOI Listing
December 2015

N(1)-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles.

Arch Dermatol Res 2015 Nov 28;307(9):841-7. Epub 2015 Jul 28.

Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s00403-015-1592-9DOI Listing
November 2015

Toward the Clonotype Analysis of Alopecia Areata-Specific, Intralesional Human CD8+ T Lymphocytes.

J Investig Dermatol Symp Proc 2015 Nov;17(2):9-12

Department of Dermatology, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1038/jidsymp.2015.31DOI Listing
November 2015

Mathematical model for alopecia areata.

J Theor Biol 2015 Sep 3;380:332-45. Epub 2015 Jun 3.

Department of Mathematics, 208 Love Building, 1017 Academic Way, Florida State University, Tallahassee, FL 32306, USA.

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http://dx.doi.org/10.1016/j.jtbi.2015.05.033DOI Listing
September 2015

Experimental Dermatology launches a new type of manuscript: 'BEDSIDE-TO-BENCH LETTER'.

Exp Dermatol 2015 Sep;24(9):643

Münster.

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http://dx.doi.org/10.1111/exd.12795DOI Listing
September 2015

Re-Evaluating Cyclosporine A as a Hair Growth-Promoting Agent in Human Scalp Hair Follicles.

J Invest Dermatol 2015 Aug 31;135(8):2129-2132. Epub 2015 Mar 31.

Centre for Dermatology Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK; Department of Dermatology, University of Muenster, Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.121DOI Listing
August 2015

The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle.

Cell Tissue Res 2015 Jun 24;360(3):761-71. Epub 2015 Feb 24.

Department of Dermatology, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv, 64239, Israel,

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http://dx.doi.org/10.1007/s00441-015-2114-yDOI Listing
June 2015

Mapping the expression of epithelial hair follicle stem cell-related transcription factors LHX2 and SOX9 in the human hair follicle.

Exp Dermatol 2015 Jun;24(6):462-7

Centre for Dermatology Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/exd.12700DOI Listing
June 2015