Publications by authors named "Ralf Paschke"

100Publications

Sensitive Sequencing Analysis Suggests Thyrotropin Receptor and Guanine Nucleotide-Binding Protein G Subunit Alpha as Sole Driver Mutations in Hot Thyroid Nodules.

Thyroid 2020 Oct 12;30(10):1482-1489. Epub 2020 May 12.

Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1089/thy.2019.0648DOI Listing
October 2020

The Thyrotropin Receptor Mutation Database Update.

Thyroid 2020 06 1;30(6):931-935. Epub 2020 Apr 1.

Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1089/thy.2019.0807DOI Listing
June 2020

Anti VEGF-TKI Treatment and New Renal Adverse Events Not Reported in Phase III Trials.

Eur Thyroid J 2018 Nov 16;7(6):308-312. Epub 2018 Aug 16.

Division of Endocrinology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1159/000491387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276742PMC
November 2018

Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice.

Thyroid 2018 10;28(10):1372-1386

1 Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku , Turku, Finland .

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https://www.liebertpub.com/doi/10.1089/thy.2018.0041
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http://dx.doi.org/10.1089/thy.2018.0041DOI Listing
October 2018

Thyroid nodule ultrasound reports in routine clinical practice provide insufficient information to estimate risk of malignancy.

Endocrine 2018 08 25;61(2):303-307. Epub 2018 May 25.

Section of Endocrinology and Metabolism, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1007/s12020-018-1634-0DOI Listing
August 2018

Inheritable and sporadic non-autoimmune hyperthyroidism.

Best Pract Res Clin Endocrinol Metab 2017 03 22;31(2):265-275. Epub 2017 Apr 22.

Division of Endocrinology and Metabolism, Chair Provincial Endocrine Tumour Team, Departments of Medicine, Oncology, Pathology and Biochemistry and Molecular Biology & Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, HMRB, Room 382B, 3330 Hospital Dr NW, Calgary, Alberta, T2N 4N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2017.04.005DOI Listing
March 2017

Molecular profiling of thyroid nodule fine-needle aspiration cytology.

Nat Rev Endocrinol 2017 07 31;13(7):415-424. Epub 2017 Mar 31.

Department of Oncology, Cumming School of Medicine, University of Calgary, Tom Baker Cancer Centre, 1331 - 29th Street NW, Calgary, Alberta T2N 4N2, Canada.

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http://dx.doi.org/10.1038/nrendo.2017.24DOI Listing
July 2017

Exploratory analysis of biomarkers associated with clinical outcomes from the study of lenvatinib in differentiated cancer of the thyroid.

Eur J Cancer 2017 04 24;75:213-221. Epub 2017 Feb 24.

Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.ejca.2017.01.013DOI Listing
April 2017

Molecular Diagnosis Using Residual Liquid-Based Cytology Materials for Patients with Nondiagnostic or Indeterminate Thyroid Nodules.

Endocrinol Metab (Seoul) 2016 Dec 4;31(4):586-591. Epub 2016 Nov 4.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.3803/EnM.2016.31.4.586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5195836PMC
December 2016

Two-miRNA classifiers differentiate mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas in fine needle aspirations with high specificity.

Endocrine 2016 Nov 29;54(2):440-447. Epub 2016 Jul 29.

Department of Oncology and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/s12020-016-1021-7DOI Listing
November 2016

[Reasonable use of imaging tests for follow-up care of thyroid cancer].

Authors:
Ralf Paschke

Dtsch Med Wochenschr 2016 Oct 17;141(21):1521. Epub 2016 Oct 17.

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http://dx.doi.org/10.1055/s-0042-117086DOI Listing
October 2016

Rearrangement of the Extracellular Domain/Extracellular Loop 1 Interface Is Critical for Thyrotropin Receptor Activation.

J Biol Chem 2016 Jul 26;291(27):14095-108. Epub 2016 Apr 26.

Division of Endocrinology and Metabolism and Arnie Charbonneau Cancer Institute University of Calgary, Calgary, Alberta T2N 1N4, Canada.

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http://dx.doi.org/10.1074/jbc.M115.709659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933169PMC
July 2016

Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma.

Am J Clin Pathol 2015 Dec;144(6):850-7

From the Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, and

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http://dx.doi.org/10.1309/AJCPEIE12POICULIDOI Listing
December 2015

In Reply.

Dtsch Arztebl Int 2015 Oct;112(42):722

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http://dx.doi.org/10.3238/arztebl.2015.0722bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644937PMC
October 2015

The Treatment of Well-Differentiated Thyroid Carcinoma.

Dtsch Arztebl Int 2015 Jun;112(26):452-8

Endocrinology and Nephrology Clinic, Leipzig University Hospital, Nuclear Medicine Clinic, Leipzig University Hospital, Clinic for Nuclear Medicine, University of Duisburg-Essen, Department of Nuclear Medicine, University Hospital of Würzburg and Klinik für Nuklearmedizin, Klinikum Augsburg, Department of General, Visceral and Vascular Surgery, University Hospital of Halle (Saale), Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital of Würzburg.

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http://dx.doi.org/10.3238/arztebl.2015.0452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515787PMC
June 2015

Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity.

Cancer Cytopathol 2015 Jun 29;123(6):356-61. Epub 2015 Apr 29.

Division of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1002/cncy.21546DOI Listing
June 2015

Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor.

PLoS One 2014 23;9(10):e111570. Epub 2014 Oct 23.

Department of Internal Medicine, Neurology and Dermatology, Division of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111570PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207802PMC
January 2016

A two miRNA classifier differentiates follicular thyroid carcinomas from follicular thyroid adenomas.

Mol Cell Endocrinol 2015 Jan 26;399:43-9. Epub 2014 Sep 26.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstr. 21, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.mce.2014.09.017DOI Listing
January 2015

Ruling in or ruling out thyroid malignancy by molecular diagnostics of thyroid nodules.

Best Pract Res Clin Endocrinol Metab 2014 Aug 2;28(4):545-57. Epub 2014 Feb 2.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstr. 20, D-04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2014.01.011DOI Listing
August 2014

A newly discovered TSHR variant (L665F) associated with nonautoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 and TM7.

J Clin Endocrinol Metab 2014 Oct 20;99(10):E2051-9. Epub 2014 Jun 20.

Department of Internal Medicine, Endocrinology, and Nephrology (H.J., J.S., M.E., S.H., R.Pa.), University of Leipzig, 04103 Leipzig, Germany; Department of Pediatrics (R.Pu., O.R.), University Hospital Salzburg, 5020 Salzburg, Austria; and Center for Structural Biology (J.M.), Vanderbilt University, Nashville, Tennessee 37232.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-1436DOI Listing
October 2014

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents.

Mol Cell Endocrinol 2014 Aug 8;393(1-2):39-45. Epub 2014 Jun 8.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstr. 20, D-04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.05.023DOI Listing
August 2014

In reply.

Authors:
Ralf Paschke

Dtsch Arztebl Int 2014 Apr;111(16):289-90

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http://dx.doi.org/10.3238/arztebl.2014.0289bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010868PMC
April 2014

[New ultrasound and molecular aspects of thyroid nodule diagnostics].

Authors:
Ralf Paschke

MMW Fortschr Med 2013 Dec;155(21-22):50-3; quiz 54

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http://dx.doi.org/10.1007/s15006-013-2404-9DOI Listing
December 2013

Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas.

Mol Cell Endocrinol 2014 May 12;388(1-2):1-9. Epub 2014 Mar 12.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstr. 21, D-04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.02.011DOI Listing
May 2014

Analysis options for high-throughput sequencing in miRNA expression profiling.

BMC Res Notes 2014 Mar 13;7:144. Epub 2014 Mar 13.

Interdisciplinary Center for Clinical Research (IZKF), University of Leipzig, Liebigstr, 21, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/1756-0500-7-144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007773PMC
March 2014

The management of thyroid nodules: a retrospective analysis of health insurance data.

Dtsch Arztebl Int 2013 Dec;110(49):827-34

Division of Nephrology-Department of Internal Medicine, Neurology and Dermatology, Universitäts - medizin Leipzig, Wissenschaftliches Institut der AOK (WIdO, AOK's Scientific Institute), Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig.

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http://dx.doi.org/10.3238/arztebl.2013.0827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884534PMC
December 2013

Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules.

Thyroid 2014 Feb 29;24(2):305-13. Epub 2013 Oct 29.

1 Division of Endocrinology and Nephrology, Statistics and Epidemiology (IMISE), Leipzig Research Center for Civilization Diseases (LIFE); University of Leipzig , Leipzig, Germany .

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http://dx.doi.org/10.1089/thy.2013.0278DOI Listing
February 2014

Inverse correlation of miRNA and cell cycle-associated genes suggests influence of miRNA on benign thyroid nodule tumorigenesis.

J Clin Endocrinol Metab 2013 Jan 8;98(1):E8-16. Epub 2012 Nov 8.

Department for Endocrinology and Nephrology, University of Leipzig, Liebigstrasse. 20, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/jc.2012-2564DOI Listing
January 2013

A patient with a large recurrent pheochromocytoma demonstrating the pitfalls of diagnosis.

Nat Rev Endocrinol 2011 Sep 6;7(12):749-55. Epub 2011 Sep 6.

Department of Endocrinology and Nephrology, University of Leipzig, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1038/nrendo.2011.132DOI Listing
September 2011

Identification of novel TSH interaction sites by systematic binding analysis of the TSHR hinge region.

Endocrinology 2011 Aug 31;152(8):3268-78. Epub 2011 May 31.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstraße 20, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/en.2011-0153DOI Listing
August 2011

Current state and future perspective of molecular diagnosis of fine-needle aspiration biopsy of thyroid nodules.

J Clin Endocrinol Metab 2011 Jul 18;96(7):2016-26. Epub 2011 May 18.

Department for Endocrinology and Nephrology, University of Leipzig, D-04103 Leipzig, Germany.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2010-2567DOI Listing
July 2011

Defining structural and functional dimensions of the extracellular thyrotropin receptor region.

J Biol Chem 2011 Jun 27;286(25):22622-31. Epub 2011 Apr 27.

Department for Structural Biology, Leibniz-Institut für Molekulare Pharmakologie, D-13125 Berlin, Germany.

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http://dx.doi.org/10.1074/jbc.M110.211193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121406PMC
June 2011

Molecular pathogenesis of nodular goiter.

Authors:
Ralf Paschke

Langenbecks Arch Surg 2011 Dec 14;396(8):1127-36. Epub 2011 Apr 14.

Department for Endocrinology and Nephrology, University of Leipzig, Liebigstrasse 20, D-04103, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00423-011-0788-5DOI Listing
December 2011

Thyroid nodule guidelines: agreement, disagreement and need for future research.

Nat Rev Endocrinol 2011 Jun 1;7(6):354-61. Epub 2011 Mar 1.

Klinik für Endokrinologie und Nephrologie, Universität Leipzig, Liebigstraße 20, D-04103 Leipzig, Germany. ralf.paschke@ medizin.uni-leipzig.de

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http://dx.doi.org/10.1038/nrendo.2011.1DOI Listing
June 2011

Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.

Thyroid 2011 Mar 29;21(3):221-9. Epub 2010 Dec 29.

Division for Endocrinology and Nephrology, Department of Medicine, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1089/thy.2010.0312DOI Listing
March 2011

[Comparison of risk factors and guideline oriented prevention and therapy of diabetic retinopathy between type 2 diabetes patients undergoing laser therapy and type 2 diabetes outpatients].

Med Klin (Munich) 2010 Nov 7;105(11):772-8. Epub 2010 Dec 7.

Medizinische Klinik und Poliklinik III in Klinik für Endokrinologie und Nephrologie, Universität Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00063-010-1131-6DOI Listing
November 2010

Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro.

Methods Enzymol 2010 ;485:421-36

Department for Internal Medicine, Neurology and Dermatology, Clinic for Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1016/B978-0-12-381296-4.00023-3DOI Listing
March 2011

Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas.

Clin Endocrinol (Oxf) 2010 Dec;73(6):815-20

Department for Internal Medicine, Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1111/j.1365-2265.2010.03872.xDOI Listing
December 2010

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study.

J Clin Endocrinol Metab 2010 Nov 4;95(11):E373-83. Epub 2010 Aug 4.

Department of Endocrinology, Centre Hospitalier Universitaire de Liège, University of Liège, Liège, Belgium.

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http://dx.doi.org/10.1210/jc.2009-2556DOI Listing
November 2010

[Drowning in a sea of thyroid nodules? Prevention and selection which nodules should undergo fine needle aspiration biopsy].

Authors:
Ralf Paschke

MMW Fortschr Med 2010 Apr;152(13):41-4

Medizinische Klinik und Poliklinik III, Universitätsklinikum Leipzig.

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http://dx.doi.org/10.1007/BF03366323DOI Listing
April 2010

Clinical implications of molecular studies for the diagnosis of thyroid cancer.

Hormones (Athens) 2010 Jan-Mar;9(1):51-6

3rd Medical Department, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.14310/horm.2002.1253DOI Listing
April 2010

Clinical application and consequences of molecular genetics of thyroid diseases.

Mol Cell Endocrinol 2010 Jun 18;322(1-2). Epub 2010 Mar 18.

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http://dx.doi.org/10.1016/j.mce.2010.03.015DOI Listing
June 2010

[Epidemiology, pathophysiology, guideline-adjusted diagnostics, and treatment of thyroid nodules].

Med Klin (Munich) 2010 Feb 20;105(2):80-7. Epub 2010 Feb 20.

Medizinische Klinik und Poliklinik III, Universitätsklinikum Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00063-010-1011-9DOI Listing
February 2010

Genetics and phenomics of inherited and sporadic non-autoimmune hyperthyroidism.

Mol Cell Endocrinol 2010 Jun 6;322(1-2):125-34. Epub 2010 Feb 6.

Section of Endocrinology and Metabolism, Vakif Gureba Education and Research Hospital, Istanbul, Turkey.

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http://dx.doi.org/10.1016/j.mce.2010.02.001DOI Listing
June 2010

Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns.

Mol Cell Endocrinol 2010 Jun 18;322(1-2):29-37. Epub 2010 Jan 18.

3rd Medical Department, University of Leipzig, Ph.-Rosenthal-Str. 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.mce.2010.01.010DOI Listing
June 2010

Calcium signaling of thyrocytes is modulated by TSH through calcium binding protein expression.

Biochim Biophys Acta 2010 Mar 18;1803(3):352-60. Epub 2010 Jan 18.

III. Medical Department, Faculty of Medicine, University of Leipzig, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2010.01.007DOI Listing
March 2010

The hinge region: an important receptor component for GPHR function.

Trends Endocrinol Metab 2010 Feb 12;21(2):111-22. Epub 2009 Oct 12.

Third Medical Department, University of Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.tem.2009.09.001DOI Listing
February 2010

Relative quantification of indium-111 pentetreotide and gallium-68 DOTATOC uptake in the thyroid gland and association with thyroid pathologies.

Thyroid 2009 Apr;19(4):381-9

Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1089/thy.2008.0389DOI Listing
April 2009

Etiology of simple goiter.

Thyroid 2009 Mar;19(3):209-11

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http://dx.doi.org/10.1089/thy.2009.0047DOI Listing
March 2009

Large genomic deletions in AIP in pituitary adenoma predisposition.

J Clin Endocrinol Metab 2008 Oct 15;93(10):4146-51. Epub 2008 Jul 15.

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2008-1003DOI Listing
October 2008

Perspectives for improved and more accurate classification of thyroid epithelial tumors.

J Clin Endocrinol Metab 2008 Sep 1;93(9):3286-94. Epub 2008 Jul 1.

Third Medical Department, University of Leipzig, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/jc.2008-0201DOI Listing
September 2008

Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor.

FASEB J 2008 Aug 1;22(8):2798-808. Epub 2008 Apr 1.

Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Str.10, D-13125 Berlin, Germany.

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http://dx.doi.org/10.1096/fj.07-104711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493456PMC
August 2008

Hypercalcemia as a result of sarcoidosis with normal serum concentrations of vitamin D.

Med Sci Monit 2007 Nov;13(11):CS133-136

Division of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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November 2007

Insights from molecular pathways: potential pharmacologic targets of benign thyroid nodules.

Curr Opin Endocrinol Diabetes Obes 2007 Oct;14(5):393-7

III Medical Department, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1097/MED.0b013e3282ef5f96DOI Listing
October 2007

Mechanisms of disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors.

Nat Clin Pract Endocrinol Metab 2007 Oct;3(10):713-20

Interdisciplinary Center for Clinical Research, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1038/ncpendmet0621DOI Listing
October 2007

[Thyroid nodules].

Authors:
Ralf Paschke

MMW Fortschr Med 2007 Mar;149(13):39-43; quiz 44

Medizinische Klinik und Poliklinik III, Universität Leipzig.

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http://dx.doi.org/10.1007/BF03364986DOI Listing
March 2007

Thyroid hormone resistance without mutations in thyroid hormone receptor beta.

Med Sci Monit 2007 Jun;13(6):CS67-70

Division of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.12659/msm.484143DOI Listing
June 2007

Modulation of TSHR signaling by posttranslational modifications.

Trends Endocrinol Metab 2007 Jul 23;18(5):199-207. Epub 2007 May 23.

Medical Department III, University of Leipzig, Ph.-Rosenthal-Str. 27, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.tem.2007.05.002DOI Listing
July 2007

Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors.

Endocr Rev 2007 May 12;28(3):322-38. Epub 2007 Mar 12.

III. Medical Department, University of Leipzig, Ph.-Rosenthal-Str. 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/er.2006-0047DOI Listing
May 2007

Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans.

Eur J Endocrinol 2007 Feb;156(2):257-61

Department of Internal Medicine III, University of Leipzig, Ph.-Rosenthal-Str. 27, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1530/eje.1.02328DOI Listing
February 2007

Selenium and goiter prevalence in borderline iodine sufficiency.

Eur J Endocrinol 2006 Dec;155(6):807-12

Third Department of Medicine, University of Leipzig, Ph-Rosenthal-Street, 27, 04103 Leipzig, Germany.

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https://eje.bioscientifica.com/view/journals/eje/155/6/15508
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http://dx.doi.org/10.1530/eje.1.02302DOI Listing
December 2006

Growth hormone induces apelin mRNA expression and secretion in mouse 3T3-L1 adipocytes.

Regul Pept 2007 Mar 28;139(1-3):84-9. Epub 2006 Nov 28.

University of Leipzig, Department of Internal Medicine III, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.regpep.2006.10.009DOI Listing
March 2007

Toward the application of proteomics to human thyroid tissue.

Thyroid 2006 Nov;16(11):1131-43

III. Medical Department, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1089/thy.2006.16.1131DOI Listing
November 2006

Contacts between extracellular loop two and transmembrane helix six determine basal activity of the thyroid-stimulating hormone receptor.

J Biol Chem 2007 Jan 1;282(1):518-25. Epub 2006 Nov 1.

Leibniz-Institut für molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, D-13125 Berlin, Germany.

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http://dx.doi.org/10.1074/jbc.M606176200DOI Listing
January 2007

Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor.

J Mol Med (Berl) 2006 Nov 6;84(11):943-54. Epub 2006 Sep 6.

III. Medical Department, University of Leipzig, Philipp-Rosenthal-Str. 27, 04103, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00109-006-0087-8DOI Listing
November 2006

Significance of ectodomain cysteine boxes 2 and 3 for the activation mechanism of the thyroid-stimulating hormone receptor.

J Biol Chem 2006 Oct 9;281(42):31638-46. Epub 2006 Aug 9.

III Medical Department, University of Leipzig, Philipp-Rosenthal-Strasse 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1074/jbc.M604770200DOI Listing
October 2006

Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.

J Med Chem 2006 Jun;49(13):3888-96

Chemical Biology Core Facility, Clinical Endocrinology Branch, and Computational Chemistry Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://pubs.acs.org/doi/abs/10.1021/jm060247s
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http://dx.doi.org/10.1021/jm060247sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543117PMC
June 2006