Publications by authors named "Ralf J Ludwig"

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The Anti-C1s Antibody TNT003 Prevents Complement Activation in the Skin Induced by Bullous Pemphigoid Autoantibodies.
J Invest Dermatol 2018 Feb 9;138(2):458-461. Epub 2017 Sep 9.
Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany; Department of Dermatology University of Lübeck, Lübeck, Germany.


Increased TREM-1 expression in inflamed skin has no functional impact on the pathogenesis of cutaneous disorders.
J Dermatol Sci 2017 Oct 30;88(1):152-155. Epub 2017 May 30.
Lübeck Institute of Experimental Dermatology, University of Lübeck, Germany; Institute of Anatomy, University of Lübeck, Germany; Lübeck Institute of Experimental Dermatology, University of Lübeck, Germany.




PDE4 Inhibition as Potential Treatment of Epidermolysis Bullosa Acquisita.
J Invest Dermatol 2016 Nov 5;136(11):2211-2220. Epub 2016 Jul 5.
Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany; Department of Dermatology, University of Lübeck, Lübeck, Germany.



Myeloid-related proteins-8 and -14 are expressed but dispensable in the pathogenesis of experimental epidermolysis bullosa acquisita and bullous pemphigoid.
J Dermatol Sci 2016 Mar 2;81(3):165-72. Epub 2015 Dec 2.
Priority Area Asthma & Allergy, Research Center Borstel, 23845 Borstel, Germany; Airway Research Center North (ARCN), Members of the German Center for Lung Research (DZL), Germany. Electronic address:



Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita.
J Immunol 2015 Sep 22;195(5):1945-54. Epub 2015 Jul 22.
Department of Dermatology, University of Lübeck, D-23538 Lübeck, Germany; Lübeck Institute of Experimental Dermatology, University of Lübeck, D-23538 Lübeck, Germany;



Caspase-1-independent IL-1 release mediates blister formation in autoantibody-induced tissue injury through modulation of endothelial adhesion molecules.
J Immunol 2015 Apr 20;194(8):3656-63. Epub 2015 Mar 20.
Department of Dermatology, University of Lübeck, 23538 Lübeck, Germany; Lübeck Institute of Experimental Dermatology, University of Lübeck, 23538 Lübeck, Germany;

Recombinant soluble CD32 suppresses disease progression in experimental epidermolysis bullosa acquisita.
J Invest Dermatol 2015 Mar 20;135(3):916-919. Epub 2014 Oct 20.
Department of Dermatology, University of Lübeck, Lübeck, Germany; Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany. Electronic address:


Flightless I over-expression impairs skin barrier development, function and recovery following skin blistering.
J Pathol 2014 Apr 5;232(5):541-52. Epub 2014 Feb 5.
Centre for Regenerative Medicine, Mawson Institute, University of South Australia, Adelaide, Australia; Women's and Children's Health Research Institute, Adelaide, Australia.




High incidence of heparin-induced allergic delayed-type hypersensitivity reactions in pregnancy.
J Allergy Clin Immunol 2013 Jul 30;132(1):131-9. Epub 2013 May 30.
Department of Internal Medicine, Division of Vascular Medicine and Hemostaseology, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany.

Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction.
J Autoimmun 2013 Feb 11;40:74-85. Epub 2012 Sep 11.
Excellence Cluster Inflammation at Interfaces, Schleswig-Holstein, Germany; Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.



Application, tolerance and safety of fondaparinux therapy in a German hospital: a prospective single-centre experience.
Thromb Res 2012 Jan 7;129(1):17-21. Epub 2011 Jul 7.
Department of Internal Medicine, Division of Vascular Medicine and Haemostaseology, J.W. Goethe University Hospital Frankfurt am Main, Germany.


The risk for cross-reactions after a cutaneous delayed-type hypersensitivity reaction to heparin preparations is independent of their molecular weight: a systematic review.
Contact Dermatitis 2011 Oct 1;65(4):187-94. Epub 2011 Jun 1.
Department of Dermatology, Venereology and Allergology, Hospital of the Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.


Low allergenic potential with fondaparinux: results of a prospective investigation.
Mayo Clin Proc 2010 Oct 15;85(10):913-9. Epub 2010 Sep 15.
Department of Internal Medicine, J. W. Goethe University Hospital, Theodor-Stern-Kai 7, Bldg. 13A, 60590 Frankfurt am Main, Germany.



T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita.
Sci Rep 2016 12 5;6:38357. Epub 2016 Dec 5.
Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.



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