Publications by authors named "Raleigh Kladney"

38 Publications

Correction to: Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer.

Oncogene 2021 Feb 9. Epub 2021 Feb 9.

Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, Saint Louis, MO, USA.

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February 2021

Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer.

Oncogene 2021 Jan 27;40(1):189-202. Epub 2020 Oct 27.

Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, Saint Louis, MO, USA.

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January 2021

Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.

Cancer Res 2020 10 30;80(19):4172-4184. Epub 2020 Jul 30.

Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

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October 2020

Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.

PLoS One 2019 26;14(12):e0226714. Epub 2019 Dec 26.

Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America.

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April 2020

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.

Cell Rep 2019 06 23;27(12):3547-3560.e5. Epub 2019 May 23.

Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address:

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June 2019

Endoreduplication of the mouse genome in the absence of ORC1.

Genes Dev 2018 07;32(13-14):978-990

Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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July 2018

Levels Serve as "Early Signature" Genes in the Development of High-Grade Serous Carcinoma from the Fallopian Tube.

Cancer Res 2018 04 16;78(7):1739-1750. Epub 2018 Jan 16.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Comprehensive Cancer Center, the Ohio State University Wexner Medical Center, Columbus, Ohio.

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April 2018

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.

Dev Cell 2017 05;41(4):392-407.e6

Solid Tumor Biology Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA; Department of Molecular Genetics, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA; Department of Cancer Biology and Genetics, McGill University, Montreal, QC H3A 1A1, Canada; Hollings Cancer Center, Medical University of South Carolina, Hollings Cancer Center 124J, 86 Jonathan Lucas Street, Charleston, SC 29425, USA. Electronic address:

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May 2017

Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.

Neoplasia 2017 Jun 11;19(6):496-508. Epub 2017 May 11.

The Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH 43210, USA. Electronic address:

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June 2017

Selective targeting of point-mutated KRAS through artificial microRNAs.

Proc Natl Acad Sci U S A 2017 05 8;114(21):E4203-E4212. Epub 2017 May 8.

Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210;

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May 2017

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.

Genes Dev 2015 Aug;29(16):1707-20

Solid Tumor Biology Program, James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA; Department of Molecular Genetics, College of Arts and Sciences, The Ohio State University, Columbus, Ohio 43210, USA; Department of Molecular Virology, Immunology, and Medical Genetics, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA;

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August 2015

Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.

Nat Cell Biol 2015 Aug 20;17(8):1036-48. Epub 2015 Jul 20.

1] Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA [2] Department of Molecular Genetics, College of Biological Sciences, The Ohio State University, Columbus, Ohio 43210, USA [3] Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.

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August 2015

Cathepsin K-Cre causes unexpected germline deletion of genes in mice.

PLoS One 2012 31;7(7):e42005. Epub 2012 Jul 31.

BRIGHT Institute and Department of Internal Medicine, Division of Molecular Oncology, Washington University School of Medicine, Saint Louis, Missouri, United States of America.

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January 2013

Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.

Mol Cancer Res 2011 Dec 4;9(12):1686-95. Epub 2011 Oct 4.

Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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December 2011

RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis.

Cancer Res 2011 Nov 21;71(21):6708-17. Epub 2011 Sep 21.

BRIGHT Institute and Department of Internal Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.

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November 2011

Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice.

Cancer Res 2010 Nov 12;70(21):8937-47. Epub 2010 Oct 12.

Division of Molecular Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA.

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November 2010