Raju Kucherlapati

Raju Kucherlapati

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Raju Kucherlapati

Publications by authors named "Raju Kucherlapati"

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An enhanced genetic model of colorectal cancer progression history.

Genome Biol 2019 08 15;20(1):168. Epub 2019 Aug 15.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s13059-019-1782-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694562PMC
August 2019

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Cell Rep 2018 07;24(2):515-527

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092947PMC
July 2018

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502825PMC
June 2017

Oliver Smithies (1925-2017).

Nature 2017 02;542(7640):166

Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA. He collaborated with Oliver Smithies on homologous recombination and other work in the 1970s and 1980s.

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http://dx.doi.org/10.1038/542166aDOI Listing
February 2017

Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.

Am J Hum Genet 2016 05;98(5):843-856

Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA; Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA; Ludwig Center, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863662PMC
May 2016

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.

Cell Rep 2016 Mar 3;14(10):2476-89. Epub 2016 Mar 3.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794376PMC
March 2016

MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas.

Cancer Prev Res (Phila) 2015 Nov 4;8(11):1112-9. Epub 2015 Sep 4.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633385PMC
November 2015

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Authors:
Daniel J Brat Roel G W Verhaak Kenneth D Aldape W K Alfred Yung Sofie R Salama Lee A D Cooper Esther Rheinbay C Ryan Miller Mark Vitucci Olena Morozova A Gordon Robertson Houtan Noushmehr Peter W Laird Andrew D Cherniack Rehan Akbani Jason T Huse Giovanni Ciriello Laila M Poisson Jill S Barnholtz-Sloan Mitchel S Berger Cameron Brennan Rivka R Colen Howard Colman Adam E Flanders Caterina Giannini Mia Grifford Antonio Iavarone Rajan Jain Isaac Joseph Jaegil Kim Katayoon Kasaian Tom Mikkelsen Bradley A Murray Brian Patrick O'Neill Lior Pachter Donald W Parsons Carrie Sougnez Erik P Sulman Scott R Vandenberg Erwin G Van Meir Andreas von Deimling Hailei Zhang Daniel Crain Kevin Lau David Mallery Scott Morris Joseph Paulauskis Robert Penny Troy Shelton Mark Sherman Peggy Yena Aaron Black Jay Bowen Katie Dicostanzo Julie Gastier-Foster Kristen M Leraas Tara M Lichtenberg Christopher R Pierson Nilsa C Ramirez Cynthia Taylor Stephanie Weaver Lisa Wise Erik Zmuda Tanja Davidsen John A Demchok Greg Eley Martin L Ferguson Carolyn M Hutter Kenna R Mills Shaw Bradley A Ozenberger Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean Claude Zenklusen Brenda Ayala Julien Baboud Sudha Chudamani Mark A Jensen Jia Liu Todd Pihl Rohini Raman Yunhu Wan Ye Wu Adrian Ally J Todd Auman Miruna Balasundaram Saianand Balu Stephen B Baylin Rameen Beroukhim Moiz S Bootwalla Reanne Bowlby Christopher A Bristow Denise Brooks Yaron Butterfield Rebecca Carlsen Scott Carter Lynda Chin Andy Chu Eric Chuah Kristian Cibulskis Amanda Clarke Simon G Coetzee Noreen Dhalla Tim Fennell Sheila Fisher Stacey Gabriel Gad Getz Richard Gibbs Ranabir Guin Angela Hadjipanayis D Neil Hayes Toshinori Hinoue Katherine Hoadley Robert A Holt Alan P Hoyle Stuart R Jefferys Steven Jones Corbin D Jones Raju Kucherlapati Phillip H Lai Eric Lander Semin Lee Lee Lichtenstein Yussanne Ma Dennis T Maglinte Harshad S Mahadeshwar Marco A Marra Michael Mayo Shaowu Meng Matthew L Meyerson Piotr A Mieczkowski Richard A Moore Lisle E Mose Andrew J Mungall Angeliki Pantazi Michael Parfenov Peter J Park Joel S Parker Charles M Perou Alexei Protopopov Xiaojia Ren Jeffrey Roach Thaís S Sabedot Jacqueline Schein Steven E Schumacher Jonathan G Seidman Sahil Seth Hui Shen Janae V Simons Payal Sipahimalani Matthew G Soloway Xingzhi Song Huandong Sun Barbara Tabak Angela Tam Donghui Tan Jiabin Tang Nina Thiessen Timothy Triche David J Van Den Berg Umadevi Veluvolu Scot Waring Daniel J Weisenberger Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Andrew W Xu Lixing Yang Travis I Zack Jianhua Zhang B Arman Aksoy Harindra Arachchi Chris Benz Brady Bernard Daniel Carlin Juok Cho Daniel DiCara Scott Frazer Gregory N Fuller JianJiong Gao Nils Gehlenborg David Haussler David I Heiman Lisa Iype Anders Jacobsen Zhenlin Ju Sol Katzman Hoon Kim Theo Knijnenburg Richard Bailey Kreisberg Michael S Lawrence William Lee Kalle Leinonen Pei Lin Shiyun Ling Wenbin Liu Yingchun Liu Yuexin Liu Yiling Lu Gordon Mills Sam Ng Michael S Noble Evan Paull Arvind Rao Sheila Reynolds Gordon Saksena Zack Sanborn Chris Sander Nikolaus Schultz Yasin Senbabaoglu Ronglai Shen Ilya Shmulevich Rileen Sinha Josh Stuart S Onur Sumer Yichao Sun Natalie Tasman Barry S Taylor Doug Voet Nils Weinhold John N Weinstein Da Yang Kosuke Yoshihara Siyuan Zheng Wei Zhang Lihua Zou Ty Abel Sara Sadeghi Mark L Cohen Jenny Eschbacher Eyas M Hattab Aditya Raghunathan Matthew J Schniederjan Dina Aziz Gene Barnett Wendi Barrett Darell D Bigner Lori Boice Cathy Brewer Chiara Calatozzolo Benito Campos Carlos Gilberto Carlotti Timothy A Chan Lucia Cuppini Erin Curley Stefania Cuzzubbo Karen Devine Francesco DiMeco Rebecca Duell J Bradley Elder Ashley Fehrenbach Gaetano Finocchiaro William Friedman Jordonna Fulop Johanna Gardner Beth Hermes Christel Herold-Mende Christine Jungk Ady Kendler Norman L Lehman Eric Lipp Ouida Liu Randy Mandt Mary McGraw Roger Mclendon Christopher McPherson Luciano Neder Phuong Nguyen Ardene Noss Raffaele Nunziata Quinn T Ostrom Cheryl Palmer Alessandro Perin Bianca Pollo Alexander Potapov Olga Potapova W Kimryn Rathmell Daniil Rotin Lisa Scarpace Cathy Schilero Kelly Senecal Kristen Shimmel Vsevolod Shurkhay Suzanne Sifri Rosy Singh Andrew E Sloan Kathy Smolenski Susan M Staugaitis Ruth Steele Leigh Thorne Daniela P C Tirapelli Andreas Unterberg Mahitha Vallurupalli Yun Wang Ronald Warnick Felicia Williams Yingli Wolinsky Sue Bell Mara Rosenberg Chip Stewart Franklin Huang Jonna L Grimsby Amie J Radenbaugh Jianan Zhang
June 2015

An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis.

Theranostics 2014 1;4(9):893-903. Epub 2014 Jul 1.

1. Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA;

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http://dx.doi.org/10.7150/thno.9425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107290PMC
April 2015

The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration.

PLoS One 2013 30;8(10):e77787. Epub 2013 Oct 30.

The G.W. Hooper Foundation, Departments of Bioengineering and Therapeutic Sciences, Pharmaceutical Chemistry, and Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America ; Department of Neurology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077787PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813726PMC
September 2014

Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma.

J Natl Cancer Inst 2014 Sep 10;106(9). Epub 2014 Sep 10.

Department of Pathology (YL, LP, RRB, WZ) and Department of Systems Biology (GBM) and Departments of Gynecologic Oncology and Reproductive Medicine and Cancer Biology (KHL, AKS), The University of Texas MD Anderson Cancer Center, Houston, TX; The Genome Institute, Washington University, St. Louis, MO (LD, ERM); Department of Genetics, Harvard Medical School, Boston, MA (RK); Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York City, NY (DAL); The Institute for Systems Biology, Seattle, WA (IS).

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http://jnci.oxfordjournals.org/content/106/9/dju245.full.pdf
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http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/dju245
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http://dx.doi.org/10.1093/jnci/dju245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200060PMC
September 2014

Next-generation sequencing identifies rare variants associated with Noonan syndrome.

Proc Natl Acad Sci U S A 2014 Aug 21;111(31):11473-8. Epub 2014 Jul 21.

Department of Genetics, Harvard Medical School, Boston, MA 02115;Department of Medicine, Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1324128111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128129PMC
August 2014

The somatic genomic landscape of glioblastoma.

Cell 2013 Oct;155(2):462-77

Human Oncology and Pathogenesis Program, Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, Department of Neurological Surgery, Weill Cornell Medical Center, New York, NY 10065, USA. Electronic address:

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https://www.genome.gov/Multimedia/Slides/TCGA2/27_Verhaak.pd
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http://linkinghub.elsevier.com/retrieve/pii/S009286741301208
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http://dx.doi.org/10.1016/j.cell.2013.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910500PMC
October 2013

In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer.

Mol Imaging 2012 Sep-Oct;11(5):417-25

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683544PMC
September 2013

Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.

Dev Biol 2013 Jun 3;378(1):13-24. Epub 2013 Apr 3.

Department of Pediatrics, USC Keck School of Medicine & Childrens Hospital Los Angeles, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/j.ydbio.2013.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838671PMC
June 2013

Francis H. Ruddle (1929-2013): a pioneer in human gene mapping.

Proc Natl Acad Sci U S A 2013 Jun 28;110(24):9619-20. Epub 2013 May 28.

Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1308094110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683742PMC
June 2013

Frank Ruddle (1929-2013).

Am J Hum Genet 2013 Jun;92(6):839-40

Department of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2013.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675234PMC
June 2013

Medical complications, clinical findings, and educational outcomes in adults with Noonan syndrome.

Am J Med Genet A 2012 Dec 19;158A(12):3106-11. Epub 2012 Nov 19.

Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/ajmg.a.35639DOI Listing
December 2012

Spectrum of somatic mitochondrial mutations in five cancers.

Proc Natl Acad Sci U S A 2012 Aug 13;109(35):14087-91. Epub 2012 Aug 13.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1211502109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435197PMC
August 2012

Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women.

Cancer Prev Res (Phila) 2012 Apr 25;5(4):655-64. Epub 2012 Jan 25.

Molecular Diagnostics Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419141PMC
April 2012

Genetically modified mouse models for biomarker discovery and preclinical drug testing.

Clin Cancer Res 2012 Feb;18(3):625-30

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-11-2021DOI Listing
February 2012

The Creating an Optimal Warfarin Nomogram (CROWN) Study.

Thromb Haemost 2012 Jan 24;107(1):59-68. Epub 2011 Nov 24.

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1160/TH11-08-0568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133142PMC
January 2012

Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model.

Hum Mol Genet 2011 Dec 9;20(24):4775-85. Epub 2011 Sep 9.

Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1093/hmg/ddr404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221538PMC
December 2011

Impaired lymphatic contraction associated with immunosuppression.

Proc Natl Acad Sci U S A 2011 Nov 7;108(46):18784-9. Epub 2011 Nov 7.

EL Steele Laboratory, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1073/pnas.1116152108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219138PMC
November 2011

Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model.

Cancer Prev Res (Phila) 2011 May 24;4(5):684-93. Epub 2011 Mar 24.

Department of Molecular Virology, Immunology & Medical Genetics, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991477PMC
May 2011

In vivo wide-area cellular imaging by side-view endomicroscopy.

Nat Methods 2010 Apr 14;7(4):303-5. Epub 2010 Mar 14.

Wellman Center for Photomedicine, Department of Dermatology, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/nmeth.1440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849759PMC
April 2010

Personalized medicine for non-small-cell lung cancer.

Oncology (Williston Park) 2010 Apr;24(5):399-400

Departments of Genetics and Medicine, Harvard Medical School, Boston, Massachusetts, USA.

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April 2010

An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.

Gastroenterology 2010 Mar 18;138(3):993-1002.e1. Epub 2009 Nov 18.

Department of Medicine/Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862591PMC
March 2010

Cis lethal genetic interactions attenuate and alter p53 tumorigenesis.

Proc Natl Acad Sci U S A 2010 Mar 8;107(12):5511-5. Epub 2010 Mar 8.

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://www.pnas.org/content/107/12/5511.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.1001223107
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http://dx.doi.org/10.1073/pnas.1001223107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851751PMC
March 2010

A suggested role for mitochondria in Noonan syndrome.

Biochim Biophys Acta 2010 Feb 14;1802(2):275-83. Epub 2009 Oct 14.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 3214 Scott Hall, 540 E. Canfield, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1016/j.bbadis.2009.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878584PMC
February 2010

DTNBP1 is associated with imaging phenotypes in schizophrenia.

Hum Brain Mapp 2009 Nov;30(11):3783-94

Laboratory of Neuro Imaging and Ahmanson-Lovelace Brain Mapping Center, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1002/hbm.20806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176807PMC
November 2009

Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.

Carcinogenesis 2009 Nov 15;30(11):1923-6. Epub 2009 Sep 15.

Strang Cancer Research Laboratory, Division of Gastroenterology and Hepatology, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1093/carcin/bgp200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783002PMC
November 2009

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection.

Nat Methods 2009 Jul 21;6(7):507-10. Epub 2009 Jun 21.

Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nmeth.1343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773433PMC
July 2009

Platform evaluation for rapid genotyping of CYP2C9 and VKORC1 alleles.

Per Med 2009 Jul;6(4):449-457

The Partners HealthCare Center for Personalized Genetic Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.2217/pme.09.8DOI Listing
July 2009

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.

J Cell Physiol 2009 May;219(2):430-7

Department of Radiation Oncology, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1002/jcp.21686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665001PMC
May 2009

A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism.

Science 2009 May;324(5931):1192-6

Department of Bioengineering and Therapeutic Sciences, University of California, School of Pharmacy, San Francisco (UCSF), San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/science.1171529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975026PMC
May 2009

Genetic mechanisms in Apc-mediated mammary tumorigenesis.

PLoS Genet 2009 Feb 6;5(2):e1000367. Epub 2009 Feb 6.

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.pgen.1000367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629572PMC
February 2009

PolyPhred analysis software for mutation detection from fluorescence-based sequence data.

Curr Protoc Hum Genet 2008 Oct;Chapter 7:Unit 7.16

Harvard Medical School - Partners Healthcare Center for Genetics and Genomics, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/0471142905.hg0716s59DOI Listing
October 2008

Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.

Mutat Res 2008 Jul 30;642(1-2):74-9. Epub 2008 Apr 30.

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2476210PMC
July 2008

Shared genetic causes of cardiac hypertrophy in children and adults.

N Engl J Med 2008 May 9;358(18):1899-908. Epub 2008 Apr 9.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1056/NEJMoa075463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752150PMC
May 2008

Genetics and genomics in the practice of medicine.

Gastroenterology 2008 May;134(5):1284-8

Harvard Medical School, Partners HealthCare Center for Genetics and Genomics, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.03.046DOI Listing
May 2008

Mutation frequencies and spectra in DNA polymerase eta-deficient mice.

Cancer Res 2008 Apr;68(7):2081-4

Buck Institute for Age Research, Novato, CA 94945, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6274DOI Listing
April 2008

Mutation detection using automated fluorescence-based sequencing.

Curr Protoc Hum Genet 2008 Apr;Chapter 7:Unit7.9

Harvard Medical School - Partners Healthcare Center for Genetics and Genomics, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/0471142905.hg0709s57DOI Listing
April 2008

SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients.

Genes Chromosomes Cancer 2008 Mar;47(3):253-9

Cancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/gcc.20527DOI Listing
March 2008

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.

Proc Natl Acad Sci U S A 2008 Mar 12;105(11):4247-52. Epub 2008 Mar 12.

Department of Cell Biology and Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.0800276105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2393764PMC
March 2008

Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia.

Proc Natl Acad Sci U S A 2007 Dec 5;104(50):19942-7. Epub 2007 Dec 5.

Department of Psychiatry Research, Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, 75-59 263rd Street, Glen Oaks, NY 11004, USA.

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http://dx.doi.org/10.1073/pnas.0710021104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148402PMC
December 2007

Pharmacogenomics of lung cancer: with a view to address EGFR-targeted therapies.

Pharmacogenomics 2007 Sep;8(9):1211-20

Harvard Medical School-Partners Healthcare Center for Genetics and Genomics, Department of Pathology, Massachusetts General Hospital, MA, USA.

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https://www.futuremedicine.com/doi/10.2217/14622416.8.9.1211
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http://dx.doi.org/10.2217/14622416.8.9.1211DOI Listing
September 2007

COMT genotype increases risk for bipolar I disorder and influences neurocognitive performance.

Bipolar Disord 2007 Jun;9(4):370-6

Department of Psychiatry Research, Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, NY 11004, USA.

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http://doi.wiley.com/10.1111/j.1399-5618.2007.00384.x
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http://dx.doi.org/10.1111/j.1399-5618.2007.00384.xDOI Listing
June 2007

A novel, single nucleotide polymorphism-based assay to detect 22q11 deletions.

Genet Test 2007 ;11(1):91-100

Harvard Medical School-Partners Healthcare Center for Genetics and Genomics, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1089/gte.2006.0507DOI Listing
May 2007

DTNBP1 genotype influences cognitive decline in schizophrenia.

Schizophr Res 2007 Jan 30;89(1-3):169-72. Epub 2006 Oct 30.

Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, NY 11004, United States.

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http://dx.doi.org/10.1016/j.schres.2006.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828039PMC
January 2007

Germline gain-of-function mutations in SOS1 cause Noonan syndrome.

Nat Genet 2007 Jan 3;39(1):70-4. Epub 2006 Dec 3.

Harvard Partners Center for Genetics and Genomics and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ng1926DOI Listing
January 2007

Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing.

Oncologist 2007 Jan;12(1):90-8

Massachusetts General Hospital Cancer Center, Harvard Medical School/Partners HealthCare Center for Genetics and Genomics, MGH Department of Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1634/theoncologist.12-1-90DOI Listing
January 2007

Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome.

Neurogenetics 2006 Nov 10;7(4):247-57. Epub 2006 Aug 10.

Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093-0627, USA.

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http://dx.doi.org/10.1007/s10048-006-0054-0DOI Listing
November 2006

Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.

Proc Natl Acad Sci U S A 2006 Nov 17;103(48):18083-8. Epub 2006 Nov 17.

Department of Pharmacology and Toxicology and James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202-1786, USA.

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http://dx.doi.org/10.1073/pnas.0605247103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838710PMC
November 2006

COMT genotype and manic symptoms in schizophrenia.

Schizophr Res 2006 Oct 7;87(1-3):28-31. Epub 2006 Jul 7.

Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, 75-59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.schres.2006.06.008DOI Listing
October 2006

Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.

PLoS Genet 2006 Sep 28;2(9):e146. Epub 2006 Jul 28.

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0020146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564426PMC
September 2006

Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model.

J Proteome Res 2006 Aug;5(8):1866-78

Gastrointestinal Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, USA.

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http://dx.doi.org/10.1021/pr060120rDOI Listing
August 2006

Epidermal growth factor receptor mutation testing in the care of lung cancer patients.

Clin Cancer Res 2006 Jul;12(14 Pt 2):4403s-4408s

Cancer Center and Department of Medicine, Massachusetts General Hospital, and Laboratory for Molecular Medicine, Harvard Medical School, Boston 02114, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0099DOI Listing
July 2006

Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis.

Cancer Res 2006 Apr;66(7):3360-4

Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2655DOI Listing
April 2006

Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.

Cancer Res 2006 Apr;66(7):3576-83

Harvard-Partners Center for Genetics and Genomics, Harvard Medical School, New Research Building 160B, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-2699DOI Listing
April 2006

Dysbindin genotype and negative symptoms in schizophrenia.

Am J Psychiatry 2006 Mar;163(3):532-4

Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, NY 11004, USA.

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http://dx.doi.org/10.1176/appi.ajp.163.3.532DOI Listing
March 2006

The finished DNA sequence of human chromosome 12.

Authors:
Steven E Scherer Donna M Muzny Christian J Buhay Rui Chen Andrew Cree Yan Ding Shannon Dugan-Rocha Rachel Gill Preethi Gunaratne R Alan Harris Alicia C Hawes Judith Hernandez Anne V Hodgson Jennifer Hume Andrew Jackson Ziad Mohid Khan Christie Kovar-Smith Lora R Lewis Ryan J Lozado Michael L Metzker Aleksandar Milosavljevic George R Miner Kate T Montgomery Margaret B Morgan Lynne V Nazareth Graham Scott Erica Sodergren Xing-Zhi Song David Steffen Ruth C Lovering David A Wheeler Kim C Worley Yi Yuan Zhengdong Zhang Charles Q Adams M Ali Ansari-Lari Mulu Ayele Mary J Brown Guan Chen Zhijian Chen Kerstin P Clerc-Blankenburg Clay Davis Oliver Delgado Huyen H Dinh Heather Draper Manuel L Gonzalez-Garay Paul Havlak Laronda R Jackson Leni S Jacob Susan H Kelly Li Li Zhangwan Li Jing Liu Wen Liu Jing Lu Manjula Maheshwari Bao-Viet Nguyen Geoffrey O Okwuonu Shiran Pasternak Lesette M Perez Farah J H Plopper Jireh Santibanez Hua Shen Paul E Tabor Daniel Verduzco Lenee Waldron Qiaoyan Wang Gabrielle A Williams Jingkun Zhang Jianling Zhou Carlana C Allen Anita G Amin Vivian Anyalebechi Michael Bailey Joseph A Barbaria Kesha E Bimage Nathaniel P Bryant Paula E Burch Carrie E Burkett Kevin L Burrell Eliana Calderon Veronica Cardenas Kelvin Carter Kristal Casias Iracema Cavazos Sandra R Cavazos Heather Ceasar Joseph Chacko Sheryl N Chan Dean Chavez Constantine Christopoulos Joseph Chu Raynard Cockrell Caroline D Cox Michelle Dang Stephanie R Dathorne Robert David Candi Mon'Et Davis Latarsha Davy-Carroll Denise R Deshazo Jeremy E Donlin Lisa D'Souza Kristy A Eaves Amy Egan Alexandra J Emery-Cohen Michael Escotto Nicole Flagg Lisa D Forbes Abdul M Gabisi Melissa Garza Cerissa Hamilton Nicholas Henderson Omar Hernandez Sandra Hines Marilyn E Hogues Mei Huang DeVincent G Idlebird Rudy Johnson Angela Jolivet Sally Jones Ryan Kagan Laquisha M King Belita Leal Heather Lebow Sandra Lee Jaclyn M LeVan Lakeshia C Lewis Pamela London Lorna M Lorensuhewa Hermela Loulseged Demetria A Lovett Alice Lucier Raymond L Lucier Jie Ma Renita C Madu Patricia Mapua Ashley D Martindale Evangelina Martinez Elizabeth Massey Samantha Mawhiney Michael G Meador Sylvia Mendez Christian Mercado Iracema C Mercado Christina E Merritt Zachary L Miner Emmanuel Minja Teresa Mitchell Farida Mohabbat Khatera Mohabbat Baize Montgomery Niki Moore Sidney Morris Mala Munidasa Robin N Ngo Ngoc B Nguyen Elizabeth Nickerson Ogechi O Nwaokelemeh Stanley Nwokenkwo Melissa Obregon Maryann Oguh Njideka Oragunye Rodolfo J Oviedo Bridgette J Parish David N Parker Julia Parrish Kenya L Parks Heidie A Paul Brett A Payton Agapito Perez William Perrin Adam Pickens Eltrick L Primus Ling-Ling Pu Maria Puazo Miyo M Quiles Juana B Quiroz Dina Rabata Kacy Reeves San Juana Ruiz Hongmei Shao Ida Sisson Titilola Sonaike Richard P Sorelle Angelica E Sutton Amanda F Svatek Leah Anne Svetz Kavitha S Tamerisa Tineace R Taylor Brian Teague Nicole Thomas Rachel D Thorn Zulma Y Trejos Brenda K Trevino Ogechi N Ukegbu Jeremy B Urban Lydia I Vasquez Virginia A Vera Donna M Villasana Ling Wang Stephanie Ward-Moore James T Warren Xuehong Wei Flower White Angela L Williamson Regina Wleczyk Hailey S Wooden Steven H Wooden Jennifer Yen Lillienne Yoon Vivienne Yoon Sara E Zorrilla David Nelson Raju Kucherlapati George Weinstock Richard A Gibbs

Nature 2006 Mar;440(7082):346-51

Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature04569DOI Listing
March 2006