Rajiv Dhir

Rajiv Dhir

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Rajiv Dhir

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Ultrasonic-assisted extraction and digestion of proteins from solid biopsies followed by peptide sequential extraction hyphenated to MALDI-based profiling holds the promise of distinguishing renal oncocytoma from chromophobe renal cell carcinoma.

Talanta 2020 Jan 27;206:120180. Epub 2019 Jul 27.

LAQV, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal; PROTEOMASS Scientific Society, Madan Park, Rua dos Inventores, 2825-152, Caparica, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2019.120180DOI Listing
January 2020

Multifocal Extraprostatic Extension of Prostate Cancer.

Am J Clin Pathol 2019 Dec 11. Epub 2019 Dec 11.

Departments of Pathology Pittsburgh, PA.

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http://dx.doi.org/10.1093/ajcp/aqz193DOI Listing
December 2019

The Biospecimen Preanalytical Variables Program: A Multiassay Comparison of Effects of Delay to Fixation and Fixation Duration on Nucleic Acid Quality.

Arch Pathol Lab Med 2019 Sep 20;143(9):1106-1118. Epub 2019 Feb 20.

From Biorepositories and Biospecimen Research Branch, Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland (Drs Carithers, Guan, Odeh, Sachs, Branton, and Moore); Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland (Drs Agarwal, Barcus, Lih, Williams, Sobin, Roche, and Mr Soria); Preferred Solutions Group, Preferred Scientific Group, Washington, District of Columbia (Dr Engel); Kelly Government Solutions, Kelly Services, Rockville, Maryland (Dr Greytak and Mr Fombonne); the Department of Pathology, University of New Mexico, Albuquerque (Dr Bocklage); the Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston, Massachusetts (Dr Andry and Ms Duffy); the Department of Pathology and Laboratory Medicine, Emory University, Winship Cancer Institute, Atlanta, Georgia (Dr Sica); the Department of Pathology, University of Pittsburg, Pittsburgh, Pennsylvania (Dr Dhir); and Van Andel Research Institute, Pathology and Biorepository Core, VARI Core Technologies and Services, Grand Rapids, Michigan (Dr Jewell).

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http://dx.doi.org/10.5858/arpa.2018-0172-OADOI Listing
September 2019

Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice.

Neoplasia 2019 08 21;21(8):752-764. Epub 2019 Jun 21.

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.neo.2019.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593215PMC
August 2019

Development of a Robust Ultrasonic-Based Sample Treatment To Unravel the Proteome of OCT-Embedded Solid Tumor Biopsies.

J Proteome Res 2019 Jul 19;18(7):2979-2986. Epub 2019 Jun 19.

BIOSCOPE Research Group, LAQV, REQUIMTE, Department of Chemistry, Faculdade de Ciências e Tecnologia , Universidade NOVA de Lisboa , 2829-516 Caparica , Portugal.

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http://dx.doi.org/10.1021/acs.jproteome.9b00248DOI Listing
July 2019

A prolonged response to platinum-based therapy in a patient with metastatic urothelial carcinoma harboring a single rearranged and truncated NF2 gene.

Genes Chromosomes Cancer 2018 08 30;57(8):430-433. Epub 2018 Mar 30.

Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/gcc.22537DOI Listing
August 2018

Utility of the laminin immunohistochemical stain in distinguishing invasive from noninvasive urothelial carcinoma.

J Cancer Res Ther 2017 Oct-Dec;13(6):947-950

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.4103/0973-1482.179523DOI Listing
July 2018

Epidermoid cyst of the renal pelvis masquerading as malignancy.

Indian J Pathol Microbiol 2017 Oct-Dec;60(4):571-573

Department of Pathology, Ohio State University Wexner Medical Center, Columbus, OH, USA.

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http://dx.doi.org/10.4103/IJPM.IJPM_618_16DOI Listing
July 2018

Clinical trial cytology: Use of on-site evaluation of small biopsy and FNA samples for clinical trials and biomarker research studies.

Cancer Cytopathol 2018 07 2;126(7). Epub 2018 May 2.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/cncy.22001DOI Listing
July 2018

BCL-2 and BCL-XL expression are down-regulated in benign prostate hyperplasia nodules and not affected by finasteride and/or celecoxib.

Am J Clin Exp Urol 2018 5;6(1):1-10. Epub 2018 Feb 5.

Department of Urology, University of Pittsburgh School of MedicinePittsburgh 15232, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840285PMC
February 2018

Next-generation sequencing-based molecular characterization of primary urinary bladder adenocarcinoma.

Mod Pathol 2017 08 26;30(8):1133-1143. Epub 2017 May 26.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/modpathol.2017.33DOI Listing
August 2017

Methods to Improve Sustainability of a Large Academic Biorepository.

Biopreserv Biobank 2017 Feb 18;15(1):31-36. Epub 2016 Nov 18.

2 Department of Pathology, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania.

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http://www.liebertpub.com/doi/10.1089/bio.2016.0076
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http://dx.doi.org/10.1089/bio.2016.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326922PMC
February 2017

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells.

Mol Endocrinol 2015 Dec 15;29(12):1731-42. Epub 2015 Sep 15.

Departments of Urology (D.W., M.M.N., K.Z.M., P.S., Y.J., K.O., J.A.D., Z.W.), Pharmacology and Chemical Biology (Z.W.), and Pathology (R.D., Z.W.) and University of Pittsburgh Cancer Institute (R.D., Z.W.), University of Pittsburgh, Pittsburgh, Pennsylvania 15232; and Department of Urology (Y.J.), The First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China.

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https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
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http://dx.doi.org/10.1210/me.2015-1112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664230PMC
December 2015

Argument for prostate cancer screening in populations of African-Caribbean origin.

BJU Int 2015 Oct 11;116(4):507-8. Epub 2015 Jun 11.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/bju.12869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406859PMC
October 2015

Data Representation, Coding, and Communication Standards.

Surg Pathol Clin 2015 Jun;8(2):109-21

Department of Pathology, University of Pittsburgh Medical Center Shadyside Hospital, 5230 Centre Avenue, Room WG 02.6, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.path.2015.02.001DOI Listing
June 2015

Amylase α-1A (AMY1A): a novel immunohistochemical marker to differentiate chromophobe renal cell carcinoma from benign oncocytoma.

Am J Surg Pathol 2013 Dec;37(12):1824-30

*Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA †Department of Pathology, East Carolina University, Greenville, NC.

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http://dx.doi.org/10.1097/PAS.0000000000000108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557609PMC
December 2013

Frozen section diagnosis: is there discordance between what pathologists say and what surgeons hear?

Am J Clin Pathol 2013 Sep;140(3):363-9

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1309/AJCPHUE5ENZDU4DJDOI Listing
September 2013

Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors.

Cancer Epidemiol 2013 Aug 23;37(4):518-22. Epub 2013 Apr 23.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.canep.2013.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684046PMC
August 2013

Partial mesenchymal to epithelial reverting transition in breast and prostate cancer metastases.

Cancer Microenviron 2012 Apr 3;5(1):19-28. Epub 2011 Sep 3.

Department of Pathology, Pittsburgh VAMC and University of Pittsburgh, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1007/s12307-011-0085-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343195PMC
April 2012

Relative quantitation of proteins in expressed prostatic secretion with a stable isotope labeled secretome standard.

J Proteome Res 2012 Feb 1;11(2):1089-99. Epub 2011 Dec 1.

Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, United States.

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http://pubs.acs.org/doi/10.1021/pr200829f
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http://dx.doi.org/10.1021/pr200829fDOI Listing
February 2012

Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion.

Mol Cancer 2012 Jan 11;11. Epub 2012 Jan 11.

Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-11-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320557PMC
January 2012

Immunohistochemical profile of paratesticular serous papillary adenocarcinoma and tunica vaginalis facilitates distinction from malignant mesothelioma.

Int J Surg Pathol 2011 Oct 3;19(5):692-8. Epub 2009 Jun 3.

Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1177/1066896909337504DOI Listing
October 2011

Increased cancer cell proliferation in prostate cancer patients with high levels of serum folate.

Prostate 2011 Sep 9;71(12):1287-93. Epub 2011 Feb 9.

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/pros.21346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120927PMC
September 2011

Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8+ T-cell-defined human tumor antigen of human carcinomas.

Cancer Immunol Immunother 2011 Jul 16;60(7):919-29. Epub 2011 Mar 16.

Division of Basic Research, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1007/s00262-011-1001-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408891PMC
July 2011

Differential proteomic analysis of renal cell carcinoma tissue interstitial fluid.

J Proteome Res 2011 Mar 12;10(3):1333-42. Epub 2011 Jan 12.

Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://pubs.acs.org/doi/abs/10.1021/pr101074p
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http://dx.doi.org/10.1021/pr101074pDOI Listing
March 2011

Hypoexpression and epigenetic regulation of candidate tumor suppressor gene CADM-2 in human prostate cancer.

Clin Cancer Res 2010 Nov 9;16(22):5390-401. Epub 2010 Nov 9.

Department of Urology, University of Pittsburgh, 5200 Centre Avenue, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541035PMC
November 2010

Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion.

Cancer Res 2010 Jun 25;70(11):4327-34. Epub 2010 May 25.

Departments of Urology and Pathology, University of Pittsburgh School of Medicine, Shadyside Medical Center, Prostate Cancer Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880218PMC
June 2010

Magnetic activated cell sorting allows isolation of spermatogonia from adult primate testes and reveals distinct GFRa1-positive subpopulations in men.

J Med Primatol 2010 Apr 15;39(2):83-91. Epub 2009 Dec 15.

Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://doi.wiley.com/10.1111/j.1600-0684.2009.00397.x
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http://dx.doi.org/10.1111/j.1600-0684.2009.00397.xDOI Listing
April 2010

Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance.

Cancer Res 2010 Mar 16;70(5):1885-95. Epub 2010 Feb 16.

Department of Surgery/Urology, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836205PMC
March 2010

Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue.

Cancer Res 2009 Sep;69(17):6831-8

Department of Human Genetics, University of Pittsburgh School of Public Health, PA, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739111PMC
September 2009

Suppressive roles of calreticulin in prostate cancer growth and metastasis.

Am J Pathol 2009 Aug 16;175(2):882-90. Epub 2009 Jul 16.

Department of Urology, University of Pittsburgh, 5200 Centre Ave., Shadyside Medical Center, Suite G40, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.2353/ajpath.2009.080417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716982PMC
August 2009

Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis.

Am J Respir Crit Care Med 2009 Jul 10;180(2):167-75. Epub 2009 Apr 10.

Division of Pulmonary, Allergy and Critical Care Medicine, Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1164/rccm.200810-1596OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714820PMC
July 2009

A multidisciplinary approach to honest broker services for tissue banks and clinical data: a pragmatic and practical model.

Cancer 2008 Oct;113(7):1705-15

Department of Pathology, University of Pittsburgh, UPMC Shadyside-Presbyterian Hospital, Pittsburgh, Pennsylvania 15232, USA.

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http://doi.wiley.com/10.1002/cncr.23768
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http://dx.doi.org/10.1002/cncr.23768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745185PMC
October 2008

Polymeric immunoglobulin receptor-negative tumors represent a more aggressive type of adenocarcinomas of distal esophagus and gastroesophageal junction.

Arch Pathol Lab Med 2008 Aug;132(8):1295-301

Department of Pathology, McGill University, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1043/1543-2165(2008)132[1295:PIRTRA]2.0.CO;2DOI Listing
August 2008

Tissue microarrays: an overview.

Authors:
Rajiv Dhir

Methods Mol Biol 2008 ;441:91-103

Department of Pathology, UPMC Shadyside-Presbyterian Hospital, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/978-1-60327-047-2_6DOI Listing
May 2008

Prostate cancer biobanking.

Authors:
Rajiv Dhir

Curr Opin Urol 2008 May;18(3):309-14

Health Sciences Tissue Bank, University of Pittsburgh UPMC Shadyside-Presbyterian Hospital, Pittsburgh, Pennsylvania 15232, USA.

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http://dx.doi.org/10.1097/MOU.0b013e3282fb7cbeDOI Listing
May 2008

p16ink4 immunoreactivity is a reliable marker for urothelial carcinoma in situ.

Hum Pathol 2008 Apr 30;39(4):527-35. Epub 2008 Jan 30.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.humpath.2007.08.005DOI Listing
April 2008

Prevalence of incidental prostate cancer in the general population: a study of healthy organ donors.

J Urol 2008 Mar 22;179(3):892-5; discussion 895. Epub 2008 Jan 22.

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.juro.2007.10.057DOI Listing
March 2008

Polyunsaturated fatty acid metabolizing 15-Lipoxygenase-1 (15-LO-1) expression in normal and tumorigenic human bladder tissues.

Appl Immunohistochem Mol Morphol 2008 Mar;16(2):159-64

Department of Urology, University of Pittsburgh , Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/PAI.0b013e31805baa41DOI Listing
March 2008

Optimization of the Affymetrix GeneChip Mapping 10K 2.0 Assay for routine clinical use on formalin-fixed paraffin-embedded tissues.

Diagn Mol Pathol 2008 Mar;17(1):3-13

Clinical Genomics Facility, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/PDM.0b013e31815aca30DOI Listing
March 2008

Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells.

Pulm Pharmacol Ther 2007 18;20(6):629-41. Epub 2006 Aug 18.

Department of Pharmacology, University of Pittsburgh, E1340 Biomedical Science Tower, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.pupt.2006.07.001DOI Listing
January 2008

Diagnostic utility of p501s (prostein) in comparison to prostate specific antigen (PSA) for the detection of metastatic prostatic adenocarcinoma.

Diagn Pathol 2007 Oct 27;2:41. Epub 2007 Oct 27.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1186/1746-1596-2-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174437PMC
October 2007

Polymorphisms of catechol-O-methyltransferase in men with renal cell cancer.

Cancer Epidemiol Biomarkers Prev 2007 Jan;16(1):92-7

Department of Urology, Veterans Affairs Medical Center and University of California at San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0605DOI Listing
January 2007

Stromal-epithelial cell interactions and androgen receptor-coregulator recruitment is altered in the tissue microenvironment of prostate cancer.

Cancer Res 2007 Jan;67(2):511-9

Department of Urologic Oncology, Roswell Park Cancer Institute, Buffalo, New York 14213, and Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1478DOI Listing
January 2007

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.

Carcinogenesis 2006 Nov 13;27(11):2223-34. Epub 2006 Jun 13.

Department of Pharmacology and University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine Pittsburgh, PA, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgl087DOI Listing
November 2006

Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma.

Am J Pathol 2006 Nov;169(5):1812-20

Department of Pathology, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, C920.1, 200 Lothrop St., Pittsburgh, PA 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780192PMC
http://dx.doi.org/10.2353/ajpath.2006.060480DOI Listing
November 2006

Diallyl trisulfide suppresses growth of PC-3 human prostate cancer xenograft in vivo in association with Bax and Bak induction.

Clin Cancer Res 2006 Nov;12(22):6836-43

Department of Pharmacology and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-06-1273DOI Listing
November 2006

Hepatic gene expression response to acute indomethacin exposure.

Mol Diagn Ther 2006 ;10(3):187-96

Department of Pathology, University of Pittsburgh School of Medicine, Shadyside Hospital, Pittsburgh, Pennsylvania 15232, USA.

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http://dx.doi.org/10.1007/BF03256457DOI Listing
October 2006

Orthotopic expression of human 15-lipoxygenase (LO)-1 in the dorsolateral prostate of normal wild-type C57BL/6 mouse causes PIN-like lesions.

Prostaglandins Other Lipid Mediat 2006 Oct 25;81(1-2):1-13. Epub 2006 Jul 25.

Department of Urology, University of Pittsburgh and Cancer Institute, PA 15232, USA.

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http://dx.doi.org/10.1016/j.prostaglandins.2006.05.024DOI Listing
October 2006

Protein kinase Cdelta signaling downstream of the EGF receptor mediates migration and invasiveness of prostate cancer cells.

Biochem Biophys Res Commun 2006 May 20;343(3):848-56. Epub 2006 Mar 20.

Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh VAMC, Pittsburgh, PA 15261, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0600548
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http://dx.doi.org/10.1016/j.bbrc.2006.03.044DOI Listing
May 2006

Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma.

Hum Pathol 2006 Apr 7;37(4):401-9. Epub 2006 Feb 7.

Department of Urology, University of Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.humpath.2005.11.022DOI Listing
April 2006

The yin and yang of 15-lipoxygenase-1 and delta-desaturases: dietary omega-6 linoleic acid metabolic pathway in prostate.

J Carcinog 2006 Mar 27;5. Epub 2006 Mar 27.

Department of Urology and University of Pittsburgh Cancer Institute, 5200 Center Ave, SHMC-Suite G-37, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1186/1477-3163-5-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440856PMC
March 2006

Contribution of the prostate limits the usefulness of survivin for the detection of bladder cancer.

J Urol 2005 Nov;174(5):1767-70

Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania 15232, USA.

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http://dx.doi.org/10.1097/01.ju.0000177070.13987.ceDOI Listing
November 2005

Age-associated changes in alpha-methyl CoA racemase (AMACR) expression in nonneoplastic prostatic tissues.

Am J Surg Pathol 2005 Nov;29(11):1435-41

Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/01.pas.0000180855.66948.5eDOI Listing
November 2005

Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak.

Mol Cancer Ther 2005 Nov;4(11):1747-54

Department of Pharmacology and University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, 2.32A Hillman Cancer Center Research Pavilion, 5117 Centre Avenue, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0223DOI Listing
November 2005

Perineural invasion in prostate cancer biopsies is not associated with higher rates of positive surgical margins.

Prostate 2005 Jun;63(4):336-40

Department of Urology, The University of Pittsburgh, Pittsburgh, Pennsylvania 15213-3232, USA.

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http://doi.wiley.com/10.1002/pros.20197
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http://dx.doi.org/10.1002/pros.20197DOI Listing
June 2005

Detection of prostate cancer with a blood-based assay for early prostate cancer antigen.

Cancer Res 2005 May;65(10):4097-100

Department of Urology, University of Pittsburgh and the University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-04-4523DOI Listing
May 2005

Prostate cancer with low PSA levels.

N Engl J Med 2004 Oct;351(17):1802-3

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October 2004

Increased apoptosis of periprostatic adipose tissue in VDR null mice.

J Cell Biochem 2004 Sep;93(1):133-41

Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1002/jcb.20172DOI Listing
September 2004