Rajesh R Singh

Rajesh R Singh

Rajesh R Singh

Rajesh R Singh

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57Publications

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Challenges in next generation sequencing analysis of somatic mutations in transplant patients.

Cancer Genet 2018 10 10;226-227:17-22. Epub 2018 May 10.

Division of Pathology and Laboratory Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Pathology, University of Alabama at Birmingham, NP 3538, 619 19th Street S, Birmingham, AL 35249-7331, United States . Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22107762173039
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http://dx.doi.org/10.1016/j.cancergen.2018.04.119DOI Listing
October 2018

Validation of quantitative PCR-based assays for detection of gene copy number aberrations in formalin-fixed, paraffin embedded solid tumor samples.

Cancer Genet 2017 04 20;212-213:24-31. Epub 2017 Mar 20.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.03.002DOI Listing
April 2017

A Targeted High-Throughput Next-Generation Sequencing Panel for Clinical Screening of Mutations, Gene Amplifications, and Fusions in Solid Tumors.

J Mol Diagn 2017 03 23;19(2):255-264. Epub 2016 Dec 23.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.09.011DOI Listing
March 2017

Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma.

Thyroid 2017 01 29;27(1):81-87. Epub 2016 Nov 29.

5 Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center , Houston, Texas.

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http://dx.doi.org/10.1089/thy.2016.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704769PMC
January 2017

Principles of analytical validation of next-generation sequencing based mutational analysis for hematologic neoplasms in a CLIA-certified laboratory.

Expert Rev Mol Diagn 2016 15;16(4):461-72. Epub 2016 Feb 15.

a Department of Hematopathology , The University of Texas at M.D. Anderson Cancer Center , Houston , TX , USA.

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http://dx.doi.org/10.1586/14737159.2016.1142374DOI Listing
December 2016

Advances in clinical next-generation sequencing: target enrichment and sequencing technologies.

Expert Rev Mol Diagn 2016 18;16(3):357-72. Epub 2016 Jan 18.

b Department of Hematopathology , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.

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http://dx.doi.org/10.1586/14737159.2016.1133298DOI Listing
November 2016

Genotyping of Frequent Mutations in Solid Tumors by PCR-Based Single-Base Extension and MassARRAY Analysis.

Methods Mol Biol 2016 ;1392:83-101

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 8515 Fannin Street, Houston, TX, 77054, USA.

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http://link.springer.com/10.1007/978-1-4939-3360-0_9
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http://dx.doi.org/10.1007/978-1-4939-3360-0_9DOI Listing
November 2016

Single-Cell Quantitative PCR: Advances and Potential in Cancer Diagnostics.

Methods Mol Biol 2016 ;1392:153-9

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 8515 Fannin Street, Houston, TX, 77054, USA.

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http://dx.doi.org/10.1007/978-1-4939-3360-0_14DOI Listing
November 2016

Factors affecting the success of next-generation sequencing in cytology specimens.

Cancer Cytopathol 2015 Nov 31;123(11):659-68. Epub 2015 Jul 31.

Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncy.21597DOI Listing
November 2015

Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies.

Cancers (Basel) 2015 Aug 28;7(3):1699-715. Epub 2015 Aug 28.

Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers7030859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586792PMC
August 2015

Comparison of next-generation sequencing mutation profiling with BRAF and IDH1 mutation-specific immunohistochemistry.

Am J Surg Pathol 2015 Apr;39(4):454-61

Departments of *Hematopathology †Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1097/PAS.0000000000000325DOI Listing
April 2015

TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow.

Am J Hematol 2013 Dec 30;88(12):1055-61. Epub 2013 Sep 30.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Pathology, King Saud University, Riyadh, Saudi Arabia.

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http://doi.wiley.com/10.1002/ajh.23567
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http://dx.doi.org/10.1002/ajh.23567DOI Listing
December 2013

Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.

J Mol Diagn 2013 Sep 26;15(5):607-22. Epub 2013 Jun 26.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2013.05.003DOI Listing
September 2013

Functional inhibition of BCL2 is needed to increase the susceptibility to apoptosis to SMO inhibitors in diffuse large B-cell lymphoma of germinal center subtype.

Ann Hematol 2013 Jun 1;92(6):777-87. Epub 2013 Feb 1.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Unit 72, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s00277-013-1684-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648611PMC
June 2013

Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma.

Leuk Res 2012 Oct 17;36(10):1267-73. Epub 2012 Jul 17.

Molecular Genetic Technology Program, School of Health Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.leukres.2012.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422406PMC
October 2012

N-terminal PAX8 polyclonal antibody shows cross-reactivity with N-terminal region of PAX5 and is responsible for reports of PAX8 positivity in malignant lymphomas.

Mod Pathol 2012 Feb 28;25(2):231-6. Epub 2011 Oct 28.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.nature.com/articles/modpathol2011162
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http://dx.doi.org/10.1038/modpathol.2011.162DOI Listing
February 2012

Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.

Mod Pathol 2009 Oct 10;22(10):1312-20. Epub 2009 Jul 10.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/modpathol.2009.98DOI Listing
October 2009

Sorptive removal of nickel onto weathered basaltic andesite products: kinetics and isotherms.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2009 Jul;44(9):880-95

Department of Chemistry, Veer Narmad South Gujarat University, Surat, India.

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July 2009

Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.

Cancer Res 2009 Mar 24;69(6):2550-8. Epub 2009 Feb 24.

Department of Hematopathology and School of Health Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1808DOI Listing
March 2009

MTA family of transcriptional metaregulators in mammary gland morphogenesis and breast cancer.

J Mammary Gland Biol Neoplasia 2007 Sep;12(2-3):115-25

Molecular and Cellular Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://link.springer.com/10.1007/s10911-007-9043-7
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http://dx.doi.org/10.1007/s10911-007-9043-7DOI Listing
September 2007

Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase.

Proc Natl Acad Sci U S A 2007 Apr 9;104(16):6782-7. Epub 2007 Apr 9.

Department of Molecular and Cellular Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1073/pnas.0701999104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871862PMC
April 2007

Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway.

Genes Dev 2006 Nov 18;20(21):2943-8. Epub 2006 Oct 18.

Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1101/gad.1461706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1620027PMC
November 2006

Solution structure and antiestrogenic activity of the unique C-terminal, NR-box motif-containing region of MTA1s.

J Biol Chem 2006 Sep 27;281(35):25612-21. Epub 2006 Jun 27.

Department of Molecular and Cellular Oncology and Experimental Therapeutics, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M604444200DOI Listing
September 2006

9-cis-retinoic acid up-regulates expression of transcriptional coregulator PELP1, a novel coactivator of the retinoid X receptor alpha pathway.

J Biol Chem 2006 Jun 30;281(22):15394-404. Epub 2006 Mar 30.

Department of Molecular and Cellular Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M601593200DOI Listing
June 2006

MTA1, a transcriptional activator of breast cancer amplified sequence 3.

Proc Natl Acad Sci U S A 2006 Apr 14;103(17):6670-5. Epub 2006 Apr 14.

Department of Molecular and Cellular Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1073/pnas.0601989103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458939PMC
April 2006

Negative regulation of estrogen receptor alpha transactivation functions by LIM domain only 4 protein.

Cancer Res 2005 Nov;65(22):10594-601

Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-2268DOI Listing
November 2005

Steroid hormone receptor signaling in tumorigenesis.

J Cell Biochem 2005 Oct;96(3):490-505

The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/jcb.20566DOI Listing
October 2005

An essential role of Pak1 phosphorylation of SHARP in Notch signaling.

Oncogene 2005 Jun;24(28):4591-6

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/sj.onc.1208672DOI Listing
June 2005

Nuclear localization and chromatin targets of p21-activated kinase 1.

J Biol Chem 2005 May 3;280(18):18130-7. Epub 2005 Mar 3.

Department of Molecular and Cellular Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M412607200DOI Listing
May 2005

Upstream determinants of estrogen receptor-alpha regulation of metastatic tumor antigen 3 pathway.

J Biol Chem 2004 Jul 28;279(31):32709-15. Epub 2004 May 28.

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M402942200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262658PMC
July 2004