Rajeev Vibhakar

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Rajeev Vibhakar

Publications by authors named "Rajeev Vibhakar"

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47Publications

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Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer.

Oncotarget 2018 Mar 17;9(17):13894-13910. Epub 2018 Feb 17.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

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March 2018

Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.

Oncol Rep 2018 Feb 29;39(2):455-464. Epub 2017 Nov 29.

Morgan Adams Foundation Pediatric Brain Tumor Research Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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February 2018

p16 Loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma.

Pediatr Blood Cancer 2017 Dec 26;64(12). Epub 2017 May 26.

Department of Pathology, The University of Colorado School of Medicine, Aurora, Colorado.

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December 2017

Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.

Oncotarget 2017 Nov 19;8(57):97290-97303. Epub 2017 Oct 19.

Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

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November 2017

NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.

Neuro Oncol 2017 Oct;19(10):1350-1360

Department of Pediatrics, University of Colorado Denver, Aurora, Colorado; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, Colorado; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado; Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.

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October 2017

Tumor treating fields in pediatric high-grade glioma.

Childs Nerv Syst 2017 Jul 3;33(7):1043-1045. Epub 2017 May 3.

Program in Neuro-Oncology, Center for Cancer and Blood Disorders, Children's Hospital Colorado, 12800 E. 19th Ave. RC1-N, Mail Stop 8302, Aurora, CO, 80045, USA.

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July 2017

Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood.

J Neuropathol Exp Neurol 2017 Jul;76(7):595-604

Morgan Adams Foundation Pediatric Brain Tumor Research Program; Department of Pathology; and Department of Neurosurgery, University of Colorado Anschutz Medical Campus; and Children's Hospital Colorado, Aurora, Colorado.

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July 2017

Vincristine and Vinblastine: Is checking bilirubin mandatory in children with Brain Tumors?

Pediatr Blood Cancer 2017 Jun 3;64(6). Epub 2016 Nov 3.

Children's Hospital Colorado, University of Colorado, School of Medicine, Aurora, Colorado.

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June 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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June 2017

Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma.

Cancer Cell Int 2017 29;17:41. Epub 2017 Mar 29.

Department of Radiation Oncology, University of Colorado Denver, Anschutz Medical Campus, 1665 Aurora Court Suite 1032, Aurora, CO 80045 USA.

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March 2017

MPS1 kinase as a potential therapeutic target in medulloblastoma.

Oncol Rep 2016 Nov 12;36(5):2633-2640. Epub 2016 Sep 12.

Department of Pediatrics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.

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November 2016

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.

Oncotarget 2016 Aug;7(33):53881-53894

Department of Pediatrics and Section of Pediatric Hematology/Oncology/BMT, Children's Hospital Colorado and University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States.

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August 2016

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.

BMC Cancer 2016 08 18;16:647. Epub 2016 Aug 18.

Department of Pediatrics, University of Colorado Denver, Anschutz Medical Campus, 12800 19th Ave, Aurora, CO, 80045, USA.

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August 2016

A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.

ACS Chem Biol 2016 Apr 8;11(4):921-30. Epub 2016 Jan 8.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , 12850 East Montview Boulevard, V20-2102, Aurora, Colorado 80045, United States.

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April 2016

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.

Authors:
Eric M Thompson Thomas Hielscher Eric Bouffet Marc Remke Betty Luu Sridharan Gururangan Roger E McLendon Darell D Bigner Eric S Lipp Sebastien Perreault Yoon-Jae Cho Gerald Grant Seung-Ki Kim Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Kay Ka Wai Li Ho-Keung Ng Yu Yao Toshihiro Kumabe Teiji Tominaga Wieslawa A Grajkowska Marta Perek-Polnik David C Y Low Wan Tew Seow Kenneth T E Chang Jaume Mora Ian F Pollack Ronald L Hamilton Sarah Leary Andrew S Moore Wendy J Ingram Andrew R Hallahan Anne Jouvet Michelle Fèvre-Montange Alexandre Vasiljevic Cecile Faure-Conter Tomoko Shofuda Naoki Kagawa Naoya Hashimoto Nada Jabado Alexander G Weil Tenzin Gayden Takafumi Wataya Tarek Shalaby Michael Grotzer Karel Zitterbart Jaroslav Sterba Leos Kren Tibor Hortobágyi Almos Klekner Bognár László Tímea Pócza Peter Hauser Ulrich Schüller Shin Jung Woo-Youl Jang Pim J French Johan M Kros Marie-Lise C van Veelen Luca Massimi Jeffrey R Leonard Joshua B Rubin Rajeev Vibhakar Lola B Chambless Michael K Cooper Reid C Thompson Claudia C Faria Alice Carvalho Sofia Nunes José Pimentel Xing Fan Karin M Muraszko Enrique López-Aguilar David Lyden Livia Garzia David J H Shih Noriyuki Kijima Christian Schneider Jennifer Adamski Paul A Northcott Marcel Kool David T W Jones Jennifer A Chan Ana Nikolic Maria Luisa Garre Erwin G Van Meir Satoru Osuka Jeffrey J Olson Arman Jahangiri Brandyn A Castro Nalin Gupta William A Weiss Iska Moxon-Emre Donald J Mabbott Alvaro Lassaletta Cynthia E Hawkins Uri Tabori James Drake Abhaya Kulkarni Peter Dirks James T Rutka Andrey Korshunov Stefan M Pfister Roger J Packer Vijay Ramaswamy Michael D Taylor

Lancet Oncol 2016 04 12;17(4):484-495. Epub 2016 Mar 12.

Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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April 2016

Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma.

Cancer Immunol Res 2015 Oct 12;3(10):1165-74. Epub 2015 May 12.

Department of Pediatrics, University of Colorado Denver, Aurora, Colorado. Children's Hospital Colorado, Aurora, Colorado. Department of Neurosurgery, University of Colorado Denver, Aurora, Colorado.

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October 2015

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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March 2014

Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.

Mol Cancer 2014 Mar 24;13:72. Epub 2014 Mar 24.

Department of Pediatrics and Section of Pediatric Hematology/Oncology/BMT, Children's Hospital Colorado and University of Colorado Denver, Anschutz Medical Campus, 12800 E 19th Ave, Mail Stop 8302, Aurora, CO, 80045, USA.

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March 2014

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

Acta Neuropathol 2013 Dec 31;126(6):917-29. Epub 2013 Oct 31.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.

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December 2013

Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.

Neuro Oncol 2013 Feb 28;15(2):149-60. Epub 2012 Nov 28.

Department of Pediatrics and Section of Pediatric Hematology/Oncology/BMT, Children’s Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA.

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February 2013

B7-H3, a potential therapeutic target, is expressed in diffuse intrinsic pontine glioma.

J Neurooncol 2013 Feb 12;111(3):257-64. Epub 2012 Dec 12.

Department of Neurological Surgery, Weill Medical College of Cornell University, 1300 York Ave, Box 99, New York, NY 10065, USA.

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February 2013

Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.

J Neurooncol 2013 Jan 9;111(2):113-21. Epub 2012 Nov 9.

Department of Pediatrics, Children's Hospital Colorado and University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.

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January 2013

MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.

J Biol Chem 2013 Jan 4;288(3):1918-28. Epub 2012 Dec 4.

Department of Pediatrics, Children’s Hospital Colorado, University of Colorado, Denver, Colorado 80045, USA.

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January 2013

Targeting the enhancer of zeste homologue 2 in medulloblastoma.

Int J Cancer 2012 Oct 30;131(8):1800-9. Epub 2012 Jul 30.

Department of Pediatrics, The Children's Hospital and University of Colorado, Anschutz Medical Campus, CO, USA.

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October 2012

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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August 2012

Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells.

J Neurooncol 2012 May 15;107(3):517-26. Epub 2012 Jan 15.

Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.

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May 2012

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.

BMC Cancer 2012 Mar 5;12:80. Epub 2012 Mar 5.

Department of Pediatrics and Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, USA.

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March 2012

Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.

Neuro Oncol 2012 Feb 8;14(2):175-83. Epub 2011 Dec 8.

Department of Pediatrics, Section of Pediatric Hematology/Oncology/BMT, University of Colorado Denver, Aurora, CO, USA.

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February 2012

Survey of MicroRNA expression in pediatric brain tumors.

Pediatr Blood Cancer 2011 Feb 3;56(2):211-6. Epub 2010 Nov 3.

Department of Neurosurgery, Anschutz Medical Campus, University of Colorado at Denver, Aurora, Colorado 80045, USA.

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February 2011

Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines.

Pediatr Blood Cancer 2010 Jul;55(1):35-41

Department of Pediatrics, University of Iowa, Iowa, USA.

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July 2010

Aurora kinase A as a rational target for therapy in glioblastoma.

J Neurosurg Pediatr 2010 Jul;6(1):98-105

Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Colorado 80045, USA.

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July 2010

Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma.

J Neurooncol 2008 Oct 8;90(1):1-7. Epub 2008 Jul 8.

Department of Pediatrics, University of Iowa Children's Hospital, University of Iowa, 5202 MERF, Iowa City, IA 52242, USA.

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October 2008

Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma.

Neuro Oncol 2007 Apr 28;9(2):135-44. Epub 2007 Feb 28.

Department of Pediatric, University of Iowa, Iowa City, IA 52242, USA.

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April 2007

Bilateral testicular masses: an unusual presentation of neuroblastoma.

Urology 2006 Sep 18;68(3):672.e15-7. Epub 2006 Sep 18.

Department of Urology, University of Iowa School of Medicine, Iowa City, Iowa 52242-1089, USA.

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September 2006

Aberrant T-cell antigen receptor-mediated responses in autoimmune lymphoproliferative syndrome.

Clin Immunol 2002 Jul;104(1):31-9

Department of Pediatrics, University of Iowa Hospitals and Clinics and Veterans Affairs Medical Center, Iowa City, 52242, USA.

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July 2002