Rajarajan A Thandavarayan

Rajarajan A Thandavarayan

UNVERIFIED PROFILE

Are you Rajarajan A Thandavarayan?   Register this Author

Register author
Rajarajan A Thandavarayan

Rajarajan A Thandavarayan

Publications by authors named "Rajarajan A Thandavarayan"

Are you Rajarajan A Thandavarayan?   Register this Author

87Publications

991Reads

14Profile Views

3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice.

Cells 2020 Mar 3;9(3). Epub 2020 Mar 3.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1, Higashijima, Akiha ku, Niigata 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells9030597DOI Listing
March 2020

Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome.

Cell Cycle 2019 Oct 14;18(19):2495-2508. Epub 2019 Aug 14.

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute , Houston , TX , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15384101.2019.1651587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738911PMC
October 2019

Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming.

Antioxid Redox Signal 2018 07 26;29(2):205-218. Epub 2018 Apr 26.

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute , Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ars.2017.7364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003401PMC
July 2018

Transflammation: Innate immune signaling in nuclear reprogramming.

Adv Drug Deliv Rev 2017 10 13;120:133-141. Epub 2017 Sep 13.

Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute (HMRI), 6670 Bertner Ave, Houston, TX 77030, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.addr.2017.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705345PMC
October 2017

Lipid-polymer hybrid nanoparticle-mediated therapeutics delivery: advances and challenges.

Drug Discov Today 2017 08 8;22(8):1258-1265. Epub 2017 Jun 8.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2017.05.015DOI Listing
August 2017

Role of 14-3-3η protein on cardiac fatty acid metabolism and macrophage polarization after high fat diet induced type 2 diabetes mellitus.

Int J Biochem Cell Biol 2017 07 5;88:92-99. Epub 2017 May 5.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biocel.2017.05.009DOI Listing
July 2017

Cardiac Mitochondrial Respiratory Dysfunction and Tissue Damage in Chronic Hyperglycemia Correlate with Reduced Aldehyde Dehydrogenase-2 Activity.

PLoS One 2016 13;11(10):e0163158. Epub 2016 Oct 13.

Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163158PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063328PMC
May 2017

The senescence accelerated mouse prone 8 (SAMP8): A novel murine model for cardiac aging.

Ageing Res Rev 2017 May 5;35:291-296. Epub 2016 Nov 5.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX 77030, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arr.2016.10.006DOI Listing
May 2017

ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes.

J Diabetes Res 2016 2;2016:1390861. Epub 2016 Nov 2.

Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA; Department of Physiology, Wayne State University, Detroit, MI 48202, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/1390861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110883PMC
May 2017

Comparative effects of torasemide and furosemide on gap junction proteins and cardiac fibrosis in a rat model of dilated cardiomyopathy.

Biofactors 2017 Mar 24;43(2):187-194. Epub 2016 Sep 24.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/biof.1332DOI Listing
March 2017

Tiny molecule, big power: Multi-target approach for curcumin in diabetic cardiomyopathy.

Nutrition 2017 Feb 30;34:47-54. Epub 2016 Sep 30.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nut.2016.09.005DOI Listing
February 2017

MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes.

Sci Rep 2016 11 9;6:36207. Epub 2016 Nov 9.

Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep36207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101812PMC
November 2016

Curcumin alleviates renal dysfunction and suppresses inflammation by shifting from M1 to M2 macrophage polarization in daunorubicin induced nephrotoxicity in rats.

Cytokine 2016 08 17;84:1-9. Epub 2016 May 17.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2016.05.001DOI Listing
August 2016

Editorial Commentary: miRNA a tiny genetic tool: Key to the puzzle of cardiovascular disease.

Trends Cardiovasc Med 2016 07 15;26(5):420-2. Epub 2016 Mar 15.

Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcm.2016.03.007DOI Listing
July 2016

Role of MAPK-mediated endoplasmic reticulum stress signaling in the heart during aging in senescence-accelerated prone mice.

Biofactors 2016 Jul 18;42(4):368-75. Epub 2016 Apr 18.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/biof.1280DOI Listing
July 2016

Increased 4-hydroxy-2-nonenal-induced proteasome dysfunction is correlated with cardiac damage in streptozotocin-injected rats with isoproterenol infusion.

Cell Biochem Funct 2016 Jul 7;34(5):334-42. Epub 2016 Jun 7.

Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbf.3195DOI Listing
July 2016

Targeting fatty acid metabolism in heart failure: is it a suitable therapeutic approach?

Drug Discov Today 2016 06 22;21(6):1003-8. Epub 2016 Feb 22.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, 265-1, Higashijima, Akiha Ku, Niigata 956 8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2016.02.010DOI Listing
June 2016

Curcumin as a therapeutic agent in the chemoprevention of inflammatory bowel disease.

Drug Discov Today 2016 05 16;21(5):843-9. Epub 2016 Mar 16.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2016.03.007DOI Listing
May 2016

Angiotensin receptor blockers: Focus on cardiac and renal injury.

Trends Cardiovasc Med 2016 Apr 15;26(3):221-8. Epub 2015 Jun 15.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Higashijima, Akiha-Ku, Niigata, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcm.2015.06.004DOI Listing
April 2016

Molecular targets of quercetin with anti-inflammatory properties in atopic dermatitis.

Drug Discov Today 2016 Apr 22;21(4):632-9. Epub 2016 Feb 22.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2016.02.011DOI Listing
April 2016

Alcohol Toxicity in Diabetes and Its Complications: A Double Trouble?

Alcohol Clin Exp Res 2016 Apr 25;40(4):686-97. Epub 2016 Mar 25.

Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acer.13008DOI Listing
April 2016

MicroRNA-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes by targeting ELAVL1.

Biochem Biophys Res Commun 2016 Mar 17;471(4):423-9. Epub 2016 Feb 17.

Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA; Cell and Developmental Biology, Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2016.02.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818978PMC
March 2016

Impaired ALDH2 activity decreases the mitochondrial respiration in H9C2 cardiomyocytes.

Cell Signal 2016 Feb 11;28(2):1-6. Epub 2015 Nov 11.

Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202, USA; Department of Physiology, Wayne State University, Detroit, MI 48202, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08986568150031
Publisher Site
http://dx.doi.org/10.1016/j.cellsig.2015.11.006DOI Listing
February 2016

Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling.

PLoS One 2015 5;10(3):e0119214. Epub 2015 Mar 5.

Basic studies on second generation functional foods, NUPALS, NUPALS Liaison R/D promotion devision, Higashi-jima 265-1, Akiha-ku, Niigata, Japan, and Changchun University of Chinese Medicine, Bosuo Road #1035 Jingyue Economic Development District, Changchun, RP China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119214PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351084PMC
January 2016

Toki-shakuyaku-san, a Japanese kampo medicine, reduces colon inflammation in a mouse model of acute colitis.

Int Immunopharmacol 2015 Dec 4;29(2):869-875. Epub 2015 Sep 4.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2015.08.029DOI Listing
December 2015

Jumihaidokuto effectively inhibits colon inflammation and apoptosis in mice with acute colitis.

Int Immunopharmacol 2015 Dec 6;29(2):957-963. Epub 2015 Nov 6.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2015.10.009DOI Listing
December 2015

RNA-stabilizing proteins as molecular targets in cardiovascular pathologies.

Trends Cardiovasc Med 2015 Nov 20;25(8):676-83. Epub 2015 Feb 20.

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcm.2015.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545469PMC
November 2015

Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377.

J Am Coll Cardiol 2015 11;66(20):2214-2226

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, Texas; Department of Cell and Developmental Biology, Department of Cardiothoracic Surgery, Weill Cornell Medical College, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2015.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644493PMC
November 2015

Enhancer-associated long noncoding RNAs: A novel frontier with new perception in cardiac regeneration.

Trends Cardiovasc Med 2015 Oct 23;25(7):603-5. Epub 2015 Feb 23.

Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcm.2015.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546919PMC
October 2015

Sirtuin-6 deficiency exacerbates diabetes-induced impairment of wound healing.

Exp Dermatol 2015 Oct 18;24(10):773-8. Epub 2015 Aug 18.

Department of Cardiovascular Sciences, Center for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.12762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583793PMC
October 2015

Small interfering RNA therapy against carbohydrate sulfotransferase 15 inhibits cardiac remodeling in rats with dilated cardiomyopathy.

Cell Signal 2015 Jul 14;27(7):1517-24. Epub 2015 Mar 14.

Department of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2015.03.004DOI Listing
July 2015

Modulation of HMGB1 translocation and RAGE/NFκB cascade by quercetin treatment mitigates atopic dermatitis in NC/Nga transgenic mice.

Exp Dermatol 2015 Jun 25;24(6):418-23. Epub 2015 Mar 25.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/exd.12685DOI Listing
June 2015

Myocardial 14-3-3η protein protects against mitochondria mediated apoptosis.

Cell Signal 2015 Apr 16;27(4):770-6. Epub 2015 Jan 16.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellsig.2014.12.021DOI Listing
April 2015

Comparative evaluation of torasemide and furosemide on rats with streptozotocin-induced diabetic nephropathy.

Exp Mol Pathol 2014 Aug 21;97(1):137-43. Epub 2014 Jun 21.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexmp.2014.06.007DOI Listing
August 2014

Olmesartan protects against oxidative stress possibly through the Nrf2 signaling pathway and inhibits inflammation in daunorubicin-induced nephrotoxicity in rats.

Int Immunopharmacol 2014 Feb 28;18(2):282-9. Epub 2013 Nov 28.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.intimp.2013.11.018DOI Listing
February 2014

Involvement of AMPK and MAPK signaling during the progression of experimental autoimmune myocarditis in rats and its blockade using a novel antioxidant.

Exp Mol Pathol 2012 Oct 18;93(2):183-9. Epub 2012 Apr 18.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexmp.2012.04.012DOI Listing
October 2012

Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC-MAPK signaling pathway.

Eur J Pharm Sci 2012 Oct 28;47(3):604-14. Epub 2012 Apr 28.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2012.04.018DOI Listing
October 2012

Modulation of endoplasmic reticulum stress and cardiomyocyte apoptosis by mulberry leaf diet in experimental autoimmune myocarditis rats.

J Clin Biochem Nutr 2012 Mar 18;50(2):139-44. Epub 2011 Nov 18.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashizima, Akiha-ku, Niigata 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3164/jcbn.11-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303476PMC
March 2012

Sex differences play a role in cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis induced by pressure overload and thapsigargin.

Cardiovasc Pathol 2011 Sep-Oct;20(5):281-90. Epub 2010 Sep 17.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carpath.2010.07.006DOI Listing
January 2012

Modulation of AT-1R/MAPK cascade by an olmesartan treatment attenuates diabetic nephropathy in streptozotocin-induced diabetic mice.

Mol Cell Endocrinol 2012 Jan 30;348(1):104-11. Epub 2011 Jul 30.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03037207110045
Publisher Site
http://dx.doi.org/10.1016/j.mce.2011.07.041DOI Listing
January 2012

Schisandrin B, attenuates cisplatin-induced oxidative stress, genotoxicity and neurotoxicity through modulating NF-κB pathway in mice.

Free Radic Res 2012 Jan;46(1):50-60

Department of Functional and Analytical Food Sciences, Niigata University of Pharmacy & Applied Life Sciences (NUPALS), Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10715762.2011.638291DOI Listing
January 2012

Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats.

Mol Nutr Food Res 2011 Nov 30;55(11):1655-65. Epub 2011 Aug 30.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mnfr.201100080
Publisher Site
http://dx.doi.org/10.1002/mnfr.201100080DOI Listing
November 2011

Carvedilol-Afforded Protection against Daunorubicin-Induced Cardiomyopathic Rats In Vivo: Effects on Cardiac Fibrosis and Hypertrophy.

ISRN Pharmacol 2011 14;2011:430549. Epub 2011 Apr 14.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima Akiha-Ku, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5402/2011/430549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197008PMC
November 2011

Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice.

Cell Physiol Biochem 2011 15;27(5):487-96. Epub 2011 Jun 15.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Higashijima, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000329970DOI Listing
October 2011

Inhibition of cardiac oxidative and endoplasmic reticulum stress-mediated apoptosis by curcumin treatment contributes to protection against acute myocarditis.

Free Radic Res 2011 Oct 18;45(10):1223-31. Epub 2011 Aug 18.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10715762.2011.607252DOI Listing
October 2011

Diabetic cardiomyopathy and oxidative stress: role of antioxidants.

Cardiovasc Hematol Agents Med Chem 2011 Oct;9(4):225-30

Department of Functional and Analytical Food Sciences, Niigata University of Pharmacy and Applied Life Sciences NUPALS, Higashijima 265-1 Akiha-Ku, Niigata, 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/187152511798120877DOI Listing
October 2011

Prevention of scopolamine-induced memory deficits by schisandrin B, an antioxidant lignan from Schisandra chinensis in mice.

Free Radic Res 2011 Aug 26;45(8):950-8. Epub 2011 May 26.

Department of Functional and Analytical Food Sciences, Niigata University of Pharmacy & Applied Life Sciences (NUPALS), Niigata city 956 8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10715762.2011.571682DOI Listing
August 2011

Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat.

Free Radic Res 2011 Jul 9;45(7):788-95. Epub 2011 May 9.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10715762.2011.579121DOI Listing
July 2011

Regulation of inflammation and myocardial fibrosis in experimental autoimmune myocarditis.

Inflamm Allergy Drug Targets 2011 Jun;10(3):218-25

Department of Clinical, Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashizima, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/187152811795564091DOI Listing
June 2011

Effect of Shengmai-san on cognitive performance and cerebral oxidative damage in BALB/c mice.

J Med Food 2011 Jun 9;14(6):601-9. Epub 2011 May 9.

Department of Functional and Analytical Food Sciences, Niigata University of Pharmacy & Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jmf.2010.1362DOI Listing
June 2011

Telmisartan prevents the progression of renal injury in daunorubicin rats with the alteration of angiotensin II and endothelin-1 receptor expression associated with its PPAR-γ agonist actions.

Toxicology 2011 Jan 1;279(1-3):91-9. Epub 2010 Oct 1.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima Akiha-ku, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2010.09.013DOI Listing
January 2011

14-3-3 protein protects against cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis in experimental diabetes.

J Pharmacol Sci 2010 13;113(4):325-34. Epub 2010 Jul 13.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1254/jphs.10047fpDOI Listing
December 2010

Partial inactivation of cardiac 14-3-3 protein in vivo elicits endoplasmic reticulum stress (ERS) and activates ERS-initiated apoptosis in ERS-induced mice.

Cell Physiol Biochem 2010 24;26(2):167-78. Epub 2010 Aug 24.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000320548DOI Listing
December 2010

Effect of telmisartan in limiting the cardiotoxic effect of daunorubicin in rats.

J Pharm Pharmacol 2010 Dec 5;62(12):1776-83. Epub 2010 Oct 5.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.2042-7158.2010.01196.xDOI Listing
December 2010

Modulation of doxorubicin-induced cardiac dysfunction in dominant-negative p38α mitogen-activated protein kinase mice.

Free Radic Biol Med 2010 Nov 10;49(9):1422-31. Epub 2010 Aug 10.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2010.08.005DOI Listing
November 2010

Beneficial effects of angiotensin II receptor blocker, olmesartan, in limiting the cardiotoxic effect of daunorubicin in rats.

Free Radic Res 2010 Nov;44(11):1369-77

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10715762.2010.509399DOI Listing
November 2010

Beneficial effects of olmesartan, an angiotensin II receptor type 1 antagonist, in rats with dilated cardiomyopathy.

Exp Biol Med (Maywood) 2010 Nov 27;235(11):1338-46. Epub 2010 Sep 27.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City 956-8603.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1258/ebm.2010.010016DOI Listing
November 2010

Arginine vasopressin receptor antagonists (vaptans): pharmacological tools and potential therapeutic agents.

Drug Discov Today 2010 Oct 11;15(19-20):826-41. Epub 2010 Aug 11.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Higashijima Akiha-ku, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2010.08.001DOI Listing
October 2010

The antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis.

Free Radic Res 2010 Sep;44(9):1082-90

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10715762.2010.499904DOI Listing
September 2010

Protective effect of carvedilol on daunorubicin-induced cardiotoxicity and nephrotoxicity in rats.

Toxicology 2010 Jul-Aug;274(1-3):18-26. Epub 2010 May 7.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima Akiha-ku, Niigata City 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2010.05.003DOI Listing
July 2010

Telmisartan, an angiotensin-II receptor blocker ameliorates cardiac remodeling in rats with dilated cardiomyopathy.

Hypertens Res 2010 Jul 10;33(7):695-702. Epub 2010 Jun 10.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/hr.2010.67DOI Listing
July 2010

Dominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus.

Am J Physiol Heart Circ Physiol 2009 Sep 17;297(3):H911-9. Epub 2009 Jul 17.

Department of Clinical Pharmacology, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima Akiha-ku, Niigata 956-8603, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00124.2009DOI Listing
September 2009

14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy.

Biochem Pharmacol 2008 May 12;75(9):1797-806. Epub 2008 Feb 12.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Niigata City, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2008.02.003DOI Listing
May 2008

Comparative effects of torasemide and furosemide in rats with heart failure.

Biochem Pharmacol 2008 Feb 5;75(3):649-59. Epub 2007 Oct 5.

Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima Akiha-ku, Niigata City, Niigata, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2007.09.026DOI Listing
February 2008