Raj N Kalaria

Raj N Kalaria

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Raj N Kalaria

Publications by authors named "Raj N Kalaria"

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Brain-derived and circulating vesicle profiles indicate neurovascular unit dysfunction in early Alzheimer's disease.

Brain Pathol 2019 Sep 31;29(5):593-605. Epub 2019 Jan 31.

School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.

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http://dx.doi.org/10.1111/bpa.12699DOI Listing
September 2019

Degenerative protein modifications in the aging vasculature and central nervous system: A problem shared is not always halved.

Ageing Res Rev 2019 Aug 19;53:100909. Epub 2019 May 19.

School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2019.100909DOI Listing
August 2019

Platelets: Peripheral Biomarkers of Dementia?

J Alzheimers Dis 2018 ;63(4):1235-1259

Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.3233/JAD-180181DOI Listing
June 2019

Neurovascular Ageing and Age-Related Diseases.

Subcell Biochem 2019;91:477-499

Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1007/978-981-13-3681-2_17DOI Listing
June 2019

Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa.

Brain Res Bull 2019 02 25;145:97-108. Epub 2018 May 25.

Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle upon Tyne NE4 5PL, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.brainresbull.2018.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252289PMC
February 2019

White matter capillaries in vascular and neurodegenerative dementias.

Acta Neuropathol Commun 2019 Feb 7;7(1):16. Epub 2019 Feb 7.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1186/s40478-019-0666-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366070PMC
February 2019

Severe white matter astrocytopathy in CADASIL.

Brain Pathol 2018 11;28(6):832-843

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/bpa.12621DOI Listing
November 2018

Montreal Cognitive Assessment score correlates with regional cerebral blood flow in post-stroke patients.

Clin Neurol Neurosurg 2018 11 5;174:68-74. Epub 2018 Sep 5.

Department of Neurology, Kyoto University Graduate School of Medicine, 606-8507 Kyoto, Japan.

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http://dx.doi.org/10.1016/j.clineuro.2018.09.004DOI Listing
November 2018

The pathology and pathophysiology of vascular dementia.

Authors:
Raj N Kalaria

Neuropharmacology 2018 05 19;134(Pt B):226-239. Epub 2017 Dec 19.

Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle Upon Tyne NE4 5PL, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.12.030DOI Listing
May 2018

White matter degeneration in vascular and other ageing-related dementias.

J Neurochem 2018 03 9;144(5):617-633. Epub 2018 Jan 9.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1111/jnc.14271DOI Listing
March 2018

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion.

J Cereb Blood Flow Metab 2018 01 3;38(1):151-165. Epub 2017 Mar 3.

1 Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1177/0271678X17694904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757440PMC
January 2018

Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy.

Acta Neuropathol Commun 2017 04 4;5(1):26. Epub 2017 Apr 4.

Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.

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http://dx.doi.org/10.1186/s40478-017-0429-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379578PMC
April 2017

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.

J Neuroinflammation 2017 04 11;14(1):81. Epub 2017 Apr 11.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1186/s12974-017-0850-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387261PMC
April 2017

STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease.

Alzheimers Dement (Amst) 2017 18;7:11-23. Epub 2016 Nov 18.

Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, Sydney, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S23528729163005
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http://dx.doi.org/10.1016/j.dadm.2016.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257024PMC
November 2016

Muscarinic M1 Receptor Coupling to G-protein is Intact in Parkinson's Disease Dementia.

J Parkinsons Dis 2016 10;6(4):733-739

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore.

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http://dx.doi.org/10.3233/JPD-160932DOI Listing
October 2016

Update on Vascular Dementia.

J Geriatr Psychiatry Neurol 2016 09;29(5):281-301

Wolfson Centre for Age Related Diseases, Guys Campus, London, United Kingdom of Great Britain and Northern Ireland

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http://dx.doi.org/10.1177/0891988716654987DOI Listing
September 2016

Age-dependent expression of VEGFR2 in deep brain arteries in small vessel disease, CADASIL, and healthy brains.

Neurobiol Aging 2016 06 10;42:110-5. Epub 2016 Mar 10.

Stroke and Dementia Research Centre, Cardiac and Cellular Sciences Research Institute, St Georges University of London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.002DOI Listing
June 2016

Stroke injury, cognitive impairment and vascular dementia.

Biochim Biophys Acta 2016 05 22;1862(5):915-25. Epub 2016 Jan 22.

Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle upon Tyne, NE4 5PL, United Kingdom; Neuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Nigeria; Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1016/j.bbadis.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827373PMC
May 2016

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease.

Authors:
Raj N Kalaria

Acta Neuropathol 2016 May 9;131(5):659-85. Epub 2016 Apr 9.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1007/s00401-016-1571-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835512PMC
May 2016

Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease.

Mol Brain 2016 Mar 17;9:27. Epub 2016 Mar 17.

Division of Chemical Biology & BioTechnology, School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore.

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http://dx.doi.org/10.1186/s13041-016-0205-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794845PMC
March 2016

Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias.

Neurobiol Aging 2016 Feb 30;38:56-67. Epub 2015 Oct 30.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle Upon Tyne, UK; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759608PMC
February 2016

Brain and other nervous system disorders across the lifespan - global challenges and opportunities.

Nature 2015 Nov;527(7578):S151-4

Institute of Neuroscience, Newcastle University, Newcastle-upon-Tyne NE4 5PL, UK.

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http://dx.doi.org/10.1038/nature16028DOI Listing
November 2015

Immunolocalization of platelet-derived growth factor receptor-β (PDGFR-β) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Neuropathol Appl Neurobiol 2015 Jun 23;41(4):557-70. Epub 2015 Apr 23.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Campus for Ageing & Vitality, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1111/nan.12188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098250PMC
June 2015

Plasma and platelet clusterin ratio is altered in Alzheimer's disease patients with distinct neuropsychiatric symptoms: findings from a pilot study.

Int J Geriatr Psychiatry 2015 Apr 12;30(4):368-75. Epub 2014 Jun 12.

Institute for Ageing and Health, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1002/gps.4145DOI Listing
April 2015

Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease.

Neurobiol Dis 2015 Feb 19;74:392-405. Epub 2014 Dec 19.

Centre for Neuroinflammation & Neurodegeneration, Division of Brain Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1016/j.nbd.2014.12.006DOI Listing
February 2015

Tau proteins in the temporal and frontal cortices in patients with vascular dementia.

J Neuropathol Exp Neurol 2015 Feb;74(2):148-57

From the Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom (EBM-L, ZA-A, ESM, ML, LJLC, AEO, RNK); and Institute of Mental Health, University of British Columbia, Vancouver, British Columbia, Canada (WGH).

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http://dx.doi.org/10.1097/NEN.0000000000000157DOI Listing
February 2015

Temporal lobe proteins implicated in synaptic failure exhibit differential expression and deamidation in vascular dementia.

Neurochem Int 2015 Jan 8;80:87-98. Epub 2014 Dec 8.

School of Biological Sciences, Nanyang Technological University, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2014.12.002DOI Listing
January 2015

White matter changes in dementia: role of impaired drainage of interstitial fluid.

Brain Pathol 2015 Jan;25(1):63-78

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://doi.wiley.com/10.1111/bpa.12218
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http://dx.doi.org/10.1111/bpa.12218DOI Listing
January 2015

iTRAQ quantitative clinical proteomics revealed role of Na(+)K(+)-ATPase and its correlation with deamidation in vascular dementia.

J Proteome Res 2014 Nov 2;13(11):4635-46. Epub 2014 Sep 2.

School of Biological Sciences, Nanyang Technological University , 60 Nanyang Drive, Singapore 637551, Singapore.

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http://pubs.acs.org/doi/10.1021/pr500754j
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http://dx.doi.org/10.1021/pr500754jDOI Listing
November 2014

Silent information regulator 2 homolog 1 counters cerebral hypoperfusion injury by deacetylating endothelial nitric oxide synthase.

Stroke 2014 Nov 11;45(11):3403-11. Epub 2014 Sep 11.

From the Department of Neurology (Y.H., R.T.) and Human Brain Research Center (N.O., H.F.), Kyoto University Graduate School of Medicine, Kyoto, Japan; Departments of Regenerative Medicine and Tissue Engineering (Y.H., Y.Y., K.Y., M.I.), Pathology (Y.O.), and Stroke and Cerebrovascular Diseases (K.N., M.I.), National Cerebral and Cardiovascular Center, Osaka, Japan; Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston (T.M.); CREST, Japan Science Technology Corporation, Saitama, Japan (R.T., M.K.); Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle Upon Tyne, United Kingdom (R.N.K.); and Division of Biological Science, Nagoya University Graduate School of Science, Nagoya, Japan (M.K.).

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http://stroke.ahajournals.org/content/45/11/3403.full.pdf
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http://stroke.ahajournals.org/lookup/doi/10.1161/STROKEAHA.1
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http://dx.doi.org/10.1161/STROKEAHA.114.006265DOI Listing
November 2014

Profile and determinants of vascular cognitive impairment in African stroke survivors: the CogFAST Nigeria Study.

J Neurol Sci 2014 Nov 1;346(1-2):241-9. Epub 2014 Sep 1.

Institute for Ageing and Health, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2014.08.042DOI Listing
November 2014

Brain lipidomes of subcortical ischemic vascular dementia and mixed dementia.

Neurobiol Aging 2014 Oct 1;35(10):2369-81. Epub 2014 Mar 1.

State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580140023
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http://dx.doi.org/10.1016/j.neurobiolaging.2014.02.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099521PMC
October 2014

Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias.

Brain 2014 Sep 28;137(Pt 9):2509-21. Epub 2014 Jun 28.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK

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http://dx.doi.org/10.1093/brain/awu172DOI Listing
September 2014

Understanding and preventing the development of post-stroke dementia.

Expert Rev Neurother 2014 Sep 8;14(9):1067-77. Epub 2014 Aug 8.

Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1586/14737175.2014.947276DOI Listing
September 2014

Microvascular pathology and morphometrics of sporadic and hereditary small vessel diseases of the brain.

Brain Pathol 2014 Sep;24(5):495-509

Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/bpa.12177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228759PMC
September 2014

Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid.

Ann Clin Transl Neurol 2014 Aug 8;1(8):519-33. Epub 2014 Jul 8.

Department of Neurology, Graduate School of Medicine, Kyoto University Kyoto, Japan ; Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center Osaka, Japan.

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http://dx.doi.org/10.1002/acn3.79DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184555PMC
August 2014

Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias.

J Neuropathol Exp Neurol 2014 Apr;73(4):305-11

From the Centre for Brain Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1097/NEN.0000000000000054DOI Listing
April 2014

Long-term incidence of depression and predictors of depressive symptoms in older stroke survivors.

Br J Psychiatry 2013 Dec 24;203(6):453-60. Epub 2013 Oct 24.

Louise M. Allan, PhD, MRCP, Elise N. Rowan, PhD, Alan J. Thomas, PhD, FRCPsych, Tuomo M. Polvikoski, MD, John T. O'Brien, DM, Raj N. Kalaria, PhD, FRCPsych, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1192/bjp.bp.113.128355DOI Listing
December 2013

Dementia: Vascular and neurodegenerative pathways-will they meet?

Nat Rev Neurol 2013 Sep 13;9(9):487-8. Epub 2013 Aug 13.

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http://dx.doi.org/10.1038/nrneurol.2013.164DOI Listing
September 2013

Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia.

Curr Alzheimer Res 2013 Jul;10(6):642-53

Institute for Ageing and Health, Campus for Ageing & Vitality, Newcastle upon Tyne, NE4 5PL, United Kingdom.

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July 2013

Brain microvascular accumulation and distribution of the NOTCH3 ectodomain and granular osmiophilic material in CADASIL.

J Neuropathol Exp Neurol 2013 May;72(5):416-31

Centre for Brain Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Campus for Ageing & Vitality, Newcastle upon Tyne, United Kingdom.

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http://jnen.oxfordjournals.org/content/jnen/72/5/416.full.pd
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http://jnen.oxfordjournals.org/cgi/doi/10.1097/NEN.0b013e318
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http://dx.doi.org/10.1097/NEN.0b013e31829020b5DOI Listing
May 2013

Increase in platelet immunoglobulin in Alzheimer's disease is normalised following cholinesterase inhibitor treatment: preliminary results.

J Alzheimers Dis 2012 ;32(2):431-6

Institute for Ageing and Health, Campus for Ageing and Vitality, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.3233/JAD-2012-120481DOI Listing
April 2013

Can healthy lifestyle modify risk factors for dementia? Findings from a pilot community-based survey in Chennai (India) and Newcastle (UK).

Neuroepidemiology 2012 30;39(3-4):163-70. Epub 2012 Aug 30.

Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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https://www.karger.com/Article/FullText/338674
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http://dx.doi.org/10.1159/000338674DOI Listing
February 2013

Synaptic proteins and choline acetyltransferase loss in visual cortex in dementia with Lewy bodies.

J Neuropathol Exp Neurol 2013 Jan;72(1):53-60

Institute for Ageing and Health, Wolfson Research Centre, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1097/NEN.0b013e31827c5710DOI Listing
January 2013

Does vascular pathology contribute to Alzheimer changes?

J Neurol Sci 2012 Nov 11;322(1-2):141-7. Epub 2012 Aug 11.

Centre for Brain Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Campus for Ageing & Vitality, Newcastle Upon Tyne NE4 5PL, United Kingdom.

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http://dx.doi.org/10.1016/j.jns.2012.07.032DOI Listing
November 2012

Cerebrovascular disease and mechanisms of cognitive impairment: evidence from clinicopathological studies in humans.

Authors:
Raj N Kalaria

Stroke 2012 Sep 9;43(9):2526-34. Epub 2012 Aug 9.

Institute for Ageing and Health, Campus for Ageing & Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1161/STROKEAHA.112.655803DOI Listing
September 2012

Delirium, dementia and senility.

Brain 2012 Sep;135(Pt 9):2582-4

Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/aws235DOI Listing
September 2012

Microangiopathy in the cerebellum of patients with mitochondrial DNA disease.

Brain 2012 Jun 9;135(Pt 6):1736-50. Epub 2012 May 9.

The Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1093/brain/aws110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359757PMC
June 2012

Platelet immunoglobulin and amyloid precursor protein as potential peripheral biomarkers for Alzheimer's disease: findings from a pilot study.

Age Ageing 2012 May 17;41(3):408-12. Epub 2012 Jan 17.

Institute for Ageing and Health, Campus for Ageing and Vitality, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1093/ageing/afr171DOI Listing
May 2012

Post-stroke dementia: the contribution of thalamus and basal ganglia changes.

Int Psychogeriatr 2012 Apr 12;24(4):568-76. Epub 2011 Dec 12.

Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1017/S1041610211002195DOI Listing
April 2012

Neuroimaging predictors of death and dementia in a cohort of older stroke survivors.

J Neurol Neurosurg Psychiatry 2012 Mar 23;83(3):263-7. Epub 2011 Nov 23.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1136/jnnp-2011-300873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289833PMC
March 2012

Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts.

Acta Neuropathol 2012 Mar 15;123(3):381-94. Epub 2011 Dec 15.

Department of Neurology, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1007/s00401-011-0925-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282897PMC
March 2012

Hippocampal neuronal atrophy and cognitive function in delayed poststroke and aging-related dementias.

Stroke 2012 Mar 29;43(3):808-14. Epub 2011 Dec 29.

Centre for Brain Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Campus for Ageing & Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1161/STROKEAHA.111.636498DOI Listing
March 2012

Increased neural progenitors in vascular dementia.

Neurobiol Aging 2011 Dec 5;32(12):2152-61. Epub 2010 Feb 5.

Stem Cell Biology Laboratory, Wolfson Centre for Age-Related Diseases, King's College London, London SE1 IUL, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S019745801000037
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http://dx.doi.org/10.1016/j.neurobiolaging.2010.01.007DOI Listing
December 2011

Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors.

Brain 2011 Dec;134(Pt 12):3716-27

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1093/brain/awr273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235558PMC
December 2011

NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors.

Neurobiol Aging 2011 Mar 5;32(3):554.e1-6. Epub 2010 Aug 5.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.06.012DOI Listing
March 2011

Revisiting dietary antioxidants, neurodegeneration and dementia.

Neuroreport 2011 Jan;22(1):1-3

Institute for Ageing and Health, Newcastle University, Newcastle Upon Tyne, UK.

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https://insights.ovid.com/crossref?an=00001756-201101050-000
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http://dx.doi.org/10.1097/WNR.0b013e328342741cDOI Listing
January 2011

Vascular basis for brain degeneration: faltering controls and risk factors for dementia.

Authors:
Raj N Kalaria

Nutr Rev 2010 Dec;68 Suppl 2:S74-87

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle Upon Tyne NE4 5PL, UK.

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https://academic.oup.com/nutritionreviews/article-lookup/doi
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http://dx.doi.org/10.1111/j.1753-4887.2010.00352.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058404PMC
December 2010

A mouse model characterizing features of vascular dementia with hippocampal atrophy.

Stroke 2010 Jun 6;41(6):1278-84. Epub 2010 May 6.

Department of Neurology, Faculty of Medicine, Kyoto University, Sakyo-Ku, Kyoto 606-8507 Japan.

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June 2010

A comparative study to screen dementia and APOE genotypes in an ageing East African population.

Neurobiol Aging 2010 May 13;31(5):732-40. Epub 2008 Aug 13.

Laboratory of Neurogeriatrics, Department of Neurology and Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2008.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857314PMC
May 2010

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies.

Acta Neuropathol 2010 May 21;119(5):579-89. Epub 2010 Jan 21.

Institute for Ageing and Health, Wolfson Research Centre, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1007/s00401-009-0635-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849937PMC
May 2010

Roll on genetics of PARK and Parkinsonism in the developing world.

J Neurol Neurosurg Psychiatry 2010 Feb;81(2):128

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http://dx.doi.org/10.1136/jnnp.2008.162834DOI Listing
February 2010

Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation.

Hum Mol Genet 2010 Jan;19(1):79-89

Department of Vascular Dementia Research, National Institute for Longevity Science, National Center for Geriatrics and Gerontology, Obu city, Aichi, Japan.

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January 2010

Linking cerebrovascular defense mechanisms in brain ageing and Alzheimer's disease.

Authors:
Raj N Kalaria

Neurobiol Aging 2009 Sep 10;30(9):1512-4. Epub 2008 Jan 10.

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September 2009

Neuropathological correlates of temporal pole white matter hyperintensities in CADASIL.

Stroke 2009 Jun 9;40(6):2004-11. Epub 2009 Apr 9.

Institute for Ageing and Health, WRC, Campus for Ageing &Vitality, Newcastle General Hospital, Westgate Road, Newcastle-upon-Tyne, NE4 6BE, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.108.528299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724668PMC
June 2009

Neurodegenerative disease: Diabetes, microvascular pathology and Alzheimer disease.

Authors:
Raj N Kalaria

Nat Rev Neurol 2009 Jun;5(6):305-6

Institute for Ageing and Health, Wolfson Research Center (Neuropathology),Newcastle General Hospital, Westgate Road,Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1038/nrneurol.2009.72DOI Listing
June 2009

Medial temporal atrophy rather than white matter hyperintensities predict cognitive decline in stroke survivors.

Neurobiol Aging 2007 Nov 24;28(11):1664-9. Epub 2006 Aug 24.

Institute for Ageing and Health, University of Newcastle, Wolfson Research Centre, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2006.07.009DOI Listing
November 2007

Cholinergic neuronal deficits in CADASIL.

Stroke 2007 Jan 22;38(1):188-91. Epub 2006 Nov 22.

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, United Kingdom.

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January 2007

Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia.

Neurobiol Aging 2006 Dec 21;27(12):1769-85. Epub 2005 Nov 21.

University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.

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December 2006

CADASIL-causing mutations do not alter Notch3 receptor processing and activation.

Neuroreport 2006 Jul;17(10):945-9

Institute for Ageing and Health, University of Newcastle, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1097/01.wnr.0000223394.66951.48DOI Listing
July 2006

Small vessel disease and subcortical vascular dementia.

J Clin Neurol 2006 Mar 20;2(1):1-11. Epub 2006 Mar 20.

Wolfson Research Centre, Institute for Ageing and Health, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, United Kingdom.

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http://dx.doi.org/10.3988/jcn.2006.2.1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854938PMC
March 2006

Vascular factors in Alzheimer's disease.

Authors:
Raj N Kalaria

Int Psychogeriatr 2003 ;15 Suppl 1:47-52

Institute for Ageing and Health, Newcastle General Hospital, and Department of Psychiatry, University of Newcastle, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1017/S1041610203008950DOI Listing
November 2005

Towards defining the neuropathological substrates of vascular dementia.

J Neurol Sci 2004 Nov;226(1-2):75-80

Institute for Ageing and Health, Newcastle General Hospital, Westgate Road, Newcastle-upon-Tyne NE4 6BE, UK.

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November 2004

Novel aspects of accumulation dynamics and A beta composition in transgenic models of AD.

Neurobiol Aging 2004 Oct;25(9):1175-85

Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Harlow, Essex CM20 2QR, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2003.12.009DOI Listing
October 2004

Hypoxia of sleep apnoea: cardiopulmonary and cerebral changes after intermittent hypoxia in rats.

Respir Physiol Neurobiol 2004 Apr;140(1):53-62

Wolfson Centre, Institute for Ageing and Health, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.resp.2004.01.003DOI Listing
April 2004